Neuron, ISSN 0896-6273, 11/2013, Volume 80, Issue 4, pp. 1090 - 1100
Serotonin and dopamine are speculated to subserve motivationally opponent functions, but this hypothesis has not been directly tested. We studied the role of...
TRANSPORTER AVAILABILITY | COGNITIVE FLEXIBILITY | INHIBITION | REINFORCEMENT | SYSTEMS | DEPLETION | REWARD | NEUROSCIENCES | MODULATION | NUCLEUS-ACCUMBENS | PARKINSONS-DISEASE | Adaptation, Psychological - physiology | Reversal Learning - physiology | Serotonin - physiology | Humans | Male | Psychomotor Performance - physiology | Young Adult | Serotonin Plasma Membrane Transport Proteins - genetics | Polymorphism, Genetic - physiology | Dopamine - physiology | Computer Simulation | Adult | Female | Dopamine Plasma Membrane Transport Proteins - physiology | Data Interpretation, Statistical | Serotonin Plasma Membrane Transport Proteins - physiology | Gambling - psychology | Reinforcement (Psychology) | Genotype | Dopamine Plasma Membrane Transport Proteins - genetics | DNA - genetics | Algorithms | Alleles | Polymorphism, Genetic - genetics | Models, Neurological | Phenols | Neurosciences | Dopamine | Serotonin | Analysis | Genes | Studies | Decision making | Feedback | Parkinsons disease | Research | Behavior | Grants | Flexibility
TRANSPORTER AVAILABILITY | COGNITIVE FLEXIBILITY | INHIBITION | REINFORCEMENT | SYSTEMS | DEPLETION | REWARD | NEUROSCIENCES | MODULATION | NUCLEUS-ACCUMBENS | PARKINSONS-DISEASE | Adaptation, Psychological - physiology | Reversal Learning - physiology | Serotonin - physiology | Humans | Male | Psychomotor Performance - physiology | Young Adult | Serotonin Plasma Membrane Transport Proteins - genetics | Polymorphism, Genetic - physiology | Dopamine - physiology | Computer Simulation | Adult | Female | Dopamine Plasma Membrane Transport Proteins - physiology | Data Interpretation, Statistical | Serotonin Plasma Membrane Transport Proteins - physiology | Gambling - psychology | Reinforcement (Psychology) | Genotype | Dopamine Plasma Membrane Transport Proteins - genetics | DNA - genetics | Algorithms | Alleles | Polymorphism, Genetic - genetics | Models, Neurological | Phenols | Neurosciences | Dopamine | Serotonin | Analysis | Genes | Studies | Decision making | Feedback | Parkinsons disease | Research | Behavior | Grants | Flexibility
Journal Article
Pharmacology and Therapeutics, ISSN 0163-7258, 2009, Volume 121, Issue 1, pp. 89 - 99
Biogenic amine transporters for serotonin, norepinephrine and dopamine (SERT, NET and DAT respectively), are the key players terminating transmission of these...
Dopamine transporter | Organic cation transporter | Norepinephrine transporter | Serotonin transporter | Antidepressants | Plasma membrane monoamine transporters | IN-VIVO MICRODIALYSIS | EXTRACELLULAR DOPAMINE | ORGANIC CATION TRANSPORTER-3 | STRIATAL DOPAMINE TERMINALS | PRELIMBIC PREFRONTAL CORTEX | MEMBRANE MONOAMINE TRANSPORTER | DEPRESSION-LIKE BEHAVIOR | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | Depression - physiopathology | Serotonin Plasma Membrane Transport Proteins - physiology | Equilibrative Nucleoside Transport Proteins - metabolism | Neurotransmitter Transport Proteins - metabolism | Organic Cation Transport Proteins - metabolism | Humans | Organic Cation Transport Proteins - physiology | Drug Discovery | Equilibrative Nucleoside Transport Proteins - physiology | Mice, Knockout - metabolism | Neurotransmitter Transport Proteins - physiology | Antidepressive Agents - therapeutic use | Serotonin Plasma Membrane Transport Proteins - metabolism | Depression - drug therapy | Serotonin Plasma Membrane Transport Proteins - genetics | Animals | Serotonin - metabolism | Neurotransmitter Transport Proteins - drug effects | Antidepressive Agents - pharmacology | Mice | Serotonin Uptake Inhibitors - pharmacology | Neurotransmitter Transport Proteins - genetics | plasma membrane monoamine transporters | antidepressants | dopamine transporter | norepinephrine transporter | serotonin transporter | organic cation transporter
Dopamine transporter | Organic cation transporter | Norepinephrine transporter | Serotonin transporter | Antidepressants | Plasma membrane monoamine transporters | IN-VIVO MICRODIALYSIS | EXTRACELLULAR DOPAMINE | ORGANIC CATION TRANSPORTER-3 | STRIATAL DOPAMINE TERMINALS | PRELIMBIC PREFRONTAL CORTEX | MEMBRANE MONOAMINE TRANSPORTER | DEPRESSION-LIKE BEHAVIOR | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | RAT-BRAIN | Depression - physiopathology | Serotonin Plasma Membrane Transport Proteins - physiology | Equilibrative Nucleoside Transport Proteins - metabolism | Neurotransmitter Transport Proteins - metabolism | Organic Cation Transport Proteins - metabolism | Humans | Organic Cation Transport Proteins - physiology | Drug Discovery | Equilibrative Nucleoside Transport Proteins - physiology | Mice, Knockout - metabolism | Neurotransmitter Transport Proteins - physiology | Antidepressive Agents - therapeutic use | Serotonin Plasma Membrane Transport Proteins - metabolism | Depression - drug therapy | Serotonin Plasma Membrane Transport Proteins - genetics | Animals | Serotonin - metabolism | Neurotransmitter Transport Proteins - drug effects | Antidepressive Agents - pharmacology | Mice | Serotonin Uptake Inhibitors - pharmacology | Neurotransmitter Transport Proteins - genetics | plasma membrane monoamine transporters | antidepressants | dopamine transporter | norepinephrine transporter | serotonin transporter | organic cation transporter
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2014, Volume 17, Issue 9, pp. 1153 - 1155
We examined epigenetic regulation in regards to behaviorally and clinically relevant human brain function. Specifically, we found that increased promoter...
NEUROSCIENCES | AMYGDALA REACTIVITY | Predictive Value of Tests | Serotonin Plasma Membrane Transport Proteins - physiology | Humans | Genotype | Linear Models | Male | Epigenesis, Genetic - physiology | Young Adult | Magnetic Resonance Imaging | Serotonin Plasma Membrane Transport Proteins - genetics | Promoter Regions, Genetic - physiology | Adolescent | Female | Models, Neurological | DNA Methylation - physiology | Amygdala - physiology | Child | Brain | Carrier proteins | Localization of functions | Genetic research | Genetic aspects | Research | Genetic regulation | Properties
NEUROSCIENCES | AMYGDALA REACTIVITY | Predictive Value of Tests | Serotonin Plasma Membrane Transport Proteins - physiology | Humans | Genotype | Linear Models | Male | Epigenesis, Genetic - physiology | Young Adult | Magnetic Resonance Imaging | Serotonin Plasma Membrane Transport Proteins - genetics | Promoter Regions, Genetic - physiology | Adolescent | Female | Models, Neurological | DNA Methylation - physiology | Amygdala - physiology | Child | Brain | Carrier proteins | Localization of functions | Genetic research | Genetic aspects | Research | Genetic regulation | Properties
Journal Article
American Journal of Psychiatry, ISSN 0002-953X, 5/2010, Volume 167, Issue 5, pp. 509 - 527
AbstractEvidence of marked variability in response among people exposed to the same environmental risk implies that individual differences in genetic...
BIASED ATTENTION | 5-HT1A RECEPTOR-BINDING | STRESSFUL LIFE EVENTS | FTO GENE | PSYCHIATRY | BODY-MASS INDEX | LINKED PROMOTER REGION | PHYSICAL-ACTIVITY | NEGATIVE AFFECTIVITY | MAJOR DEPRESSION | REGION 5-HTTLPR POLYMORPHISM | Depressive Disorder - genetics | Primates - psychology | Genetic Predisposition to Disease - genetics | Serotonin Plasma Membrane Transport Proteins - physiology | Mood Disorders - genetics | Brain - physiopathology | Humans | Models, Psychological | Genotype | Stress, Psychological - genetics | Primates - genetics | Serotonin Plasma Membrane Transport Proteins - genetics | Animals | Brain - pathology | Environment | Genome-Wide Association Study - methods | Stress, Psychological - complications | Phenols | Physiological aspects | Genetic aspects | Serotonin | Depressive Disorders | Survivors | Neurobiology | Genetic Markers | Effects | Neurotransmitters | Literature Review | Genetics | Adults | Children | Adolescents | Stressors | Animal Models
BIASED ATTENTION | 5-HT1A RECEPTOR-BINDING | STRESSFUL LIFE EVENTS | FTO GENE | PSYCHIATRY | BODY-MASS INDEX | LINKED PROMOTER REGION | PHYSICAL-ACTIVITY | NEGATIVE AFFECTIVITY | MAJOR DEPRESSION | REGION 5-HTTLPR POLYMORPHISM | Depressive Disorder - genetics | Primates - psychology | Genetic Predisposition to Disease - genetics | Serotonin Plasma Membrane Transport Proteins - physiology | Mood Disorders - genetics | Brain - physiopathology | Humans | Models, Psychological | Genotype | Stress, Psychological - genetics | Primates - genetics | Serotonin Plasma Membrane Transport Proteins - genetics | Animals | Brain - pathology | Environment | Genome-Wide Association Study - methods | Stress, Psychological - complications | Phenols | Physiological aspects | Genetic aspects | Serotonin | Depressive Disorders | Survivors | Neurobiology | Genetic Markers | Effects | Neurotransmitters | Literature Review | Genetics | Adults | Children | Adolescents | Stressors | Animal Models
Journal Article