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Journal Article
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 2012, Volume 219, Issue 2, pp. 313 - 326
High levels of impulsivity are a core symptom of psychiatric disorders such as ADHD, mania, personality disorders and drug addiction. The effectiveness of... 
Neurosciences | Impulsivity | Biomedicine | Dopamine | Serotonin | Delayed reward | Pharmacology/Toxicology | Psychiatry | Noradrenaline | Five-choice serial reaction time task | PSYCHIATRY | GLOBAL 5-HT DEPLETION | DEFICIT-HYPERACTIVITY DISORDER | TERM ATOMOXETINE TREATMENT | NEUROSCIENCES | REACTION-TIME-TASK | PREFRONTAL CORTEX | ATTENTION-DEFICIT/HYPERACTIVITY DISORDER | RESPONSE-INHIBITION | NUCLEUS-ACCUMBENS CORE | NOREPINEPHRINE TRANSPORTER | PHARMACOLOGY & PHARMACY | D-AMPHETAMINE | Citalopram - pharmacology | Dopamine Uptake Inhibitors - therapeutic use | Male | Dose-Response Relationship, Drug | Time Factors | Reaction Time - drug effects | Atomoxetine Hydrochloride | Serial Learning - drug effects | Animals, Outbred Strains | Choice Behavior - drug effects | Adrenergic Uptake Inhibitors - therapeutic use | Dopamine Uptake Inhibitors - pharmacology | Amphetamine - therapeutic use | Amphetamine - pharmacology | Serotonin Uptake Inhibitors - therapeutic use | Rats | Piperazines - therapeutic use | Piperazines - pharmacology | Animals | Propylamines - therapeutic use | Adrenergic Uptake Inhibitors - pharmacology | Citalopram - therapeutic use | Impulsive Behavior - drug therapy | Propylamines - pharmacology | Serotonin Uptake Inhibitors - pharmacology | Antidepressants | Mental illness | Neurotransmitters | Inhibitor drugs | Response time | Animal behavior | Rodents | Psychopharmacology | Drug abuse | Drug addiction | Mental disorders | Attention deficit hyperactivity disorder | impulsive behavior | Drug delivery | Personality | Reaction time task | Intertrial interval | Amphetamine | Affective disorders | Reinforcement | Norepinephrine | citalopram | Neurotransmission | monoamines | Original Investigation
Journal Article
Science, ISSN 0036-8075, 9/2010, Volume 329, Issue 5998, pp. 1537 - 1541
The serotonin transporter (SERT) ensures the recapture of serotonin and is the pharmacological target of selective serotonin reuptake inhibitor (SSRI)... 
Receptors | MicroRNA | Serotonin agents | Neurons | Antidepressants | Serotonin receptors | REPORTS | Cell lines | Serotonin plasma membrane transport proteins | Adrenergic neurons | Locus coeruleus | LOCUS-COERULEUS | CELLS | RECEPTOR | RECOGNITION | RAT | MULTIDISCIPLINARY SCIENCES | Up-Regulation | Protein Biosynthesis | Humans | MicroRNAs - metabolism | Nerve Growth Factors - metabolism | Antidepressive Agents, Second-Generation - administration & dosage | Raphe Nuclei - metabolism | Serotonin Plasma Membrane Transport Proteins - genetics | Neurons - metabolism | 3' Untranslated Regions | Neurons - drug effects | Serotonin Uptake Inhibitors - metabolism | Cell Line | Fluoxetine - pharmacology | S100 Calcium Binding Protein beta Subunit | MicroRNAs - administration & dosage | Depression | S100 Proteins - metabolism | Antidepressive Agents, Second-Generation - pharmacology | Serotonin Plasma Membrane Transport Proteins - metabolism | Animals | Norepinephrine - metabolism | Raphe Nuclei - drug effects | Serotonin Uptake Inhibitors - administration & dosage | Serotonin - metabolism | Fluoxetine - administration & dosage | Fluoxetine - metabolism | Mice | MicroRNAs - genetics | HeLa Cells | Antidepressive Agents, Second-Generation - metabolism | Serotonin Uptake Inhibitors - pharmacology | Locus Coeruleus - metabolism | Pharmacogenetics | Serotonin | Physiological aspects | Serotonin uptake inhibitors | Dosage and administration | Research | Health aspects | Pharmacology
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2011, Volume 54, Issue 9, pp. 3206 - 3221
The synthesis and structure-activity relationship of a novel series of compounds with combined effects on 5-HT3A and 5-HT1A receptors and on the serotonin... 
FREELY MOVING RATS | ARYL BROMIDES | SEROTONIN REUPTAKE INHIBITORS | IN-VIVO MICRODIALYSIS | CHEMISTRY, MEDICINAL | PALLADIUM-CATALYZED SYNTHESIS | 5-HT1A RECEPTORS | MOOD DISORDERS | DRUG DISCOVERY | FRONTAL-CORTEX | ANTIDEPRESSANT-LIKE BEHAVIOR | Xenopus | Humans | Microsomes, Liver - metabolism | Receptor, Serotonin, 5-HT2C - metabolism | Sulfides - chemistry | Serotonin 5-HT1 Receptor Agonists - pharmacology | Sulfides - chemical synthesis | Piperazines - chemistry | Structure-Activity Relationship | Hippocampus - drug effects | Serotonin Uptake Inhibitors - chemical synthesis | Receptors, Serotonin, 5-HT1 - metabolism | Serotonin 5-HT1 Receptor Agonists - chemistry | Antidepressive Agents - chemistry | Oocytes - drug effects | Antidepressive Agents - pharmacology | Radioligand Assay | Serotonin 5-HT3 Receptor Antagonists - chemistry | Receptor, Serotonin, 5-HT1A - metabolism | Depressive Disorder, Major - drug therapy | Sulfides - pharmacology | Cell Line | Recombinant Proteins - antagonists & inhibitors | Drug Partial Agonism | Drug Stability | Rats | Serotonin Uptake Inhibitors - chemistry | Serotonin 5-HT1 Receptor Agonists - chemical synthesis | Recombinant Proteins - agonists | Piperazines - pharmacology | Receptors, Serotonin - metabolism | Serotonin 5-HT3 Receptor Antagonists - chemical synthesis | Serotonin Plasma Membrane Transport Proteins - metabolism | Hippocampus - metabolism | Animals | Oocytes - physiology | Receptors, Serotonin, 5-HT3 - metabolism | Serotonin - metabolism | Antidepressive Agents - chemical synthesis | Piperazines - chemical synthesis | Serotonin 5-HT3 Receptor Antagonists - pharmacology | In Vitro Techniques | Serotonin Uptake Inhibitors - pharmacology
Journal Article
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 11/2009, Volume 52, Issue 21, pp. 6768 - 6781
Journal Article
Journal Article