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1. Full Text Defining the blanks – Pharmacochaperoning of SLC6 transporters and ABC transporters
by Chiba, Peter and Freissmuth, Michael and Stockner, Thomas
Pharmacological research, ISSN 1043-6618, 05/2014, Volume 83, Issue 100, pp. 63 - 73
SLC6 transporters | ABC transporters | Folding-deficient mutants | Chaperones | Pharmacochaperoning | ER export | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | ATP-Binding Cassette Transporters - chemistry | Animals | ATP-Binding Cassette Transporters - genetics | Membrane Transport Proteins - genetics | Protein Folding - drug effects | Humans | Protein Conformation - drug effects | Models, Molecular | Ligands | Mutation | Drug Discovery | Membrane Transport Proteins - chemistry | Index Medicus | DAT, dopamine transporter | GAT, GABA transporter with 4 isoforms (GAT-1, GAT-2, GAT-3, GAT-4) | NET, norepinephrine transporter | SLC6, solute carrier-6 | SERT, serotonin transporter | ABC transporters, ATP-binding cassette containing transporters | ER, endoplasmic reticulum | NBD, nucleotide binding domains
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2. Full Text Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotype
by Reimold, M and Smolka, M. N and Schumann, G and Zimmer, A and Wrase, J and Mann, K and Hu, X.-Z and Goldman, D and Reischl, G and Solbach, C and Machulla, H.-J and Bares, R and Heinz, A
Journal of Neural Transmission, ISSN 0300-9564, 5/2007, Volume 114, Issue 5, pp. 635 - 639
Neurology | 5-HTT, SCL6A4, PET, DASB | Medicine & Public Health | Pharmacology/Toxicology | Psychiatry | 5-HTT | SCL6A4 | DASB | PET | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Amygdala - diagnostic imaging | Thalamus - metabolism | Mesencephalon - metabolism | Thalamus - diagnostic imaging | Gene Frequency | Humans | Middle Aged | Amygdala - metabolism | Genotype | Male | Positron-Emission Tomography | Serotonin Plasma Membrane Transport Proteins - metabolism | Homozygote | Mesencephalon - diagnostic imaging | Serotonin Plasma Membrane Transport Proteins - genetics | Neural Pathways - diagnostic imaging | Serotonin - metabolism | Neural Pathways - metabolism | Adult | Binding, Competitive - genetics | Female | Heterozygote | Benzylamines - pharmacokinetics | Carbon Radioisotopes | Index Medicus
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3. Full Text Effect of a Triallelic Functional Polymorphism of the Serotonin-Transporter-Linked Promoter Region on Expression of Serotonin Transporter in the Human Brain
by Parsey, Ramin V and Hastings, Ramin S and Oquendo, Maria A and Hu, Xianzhang and Goldman, David and Huang, Yung-yu and Simpson, Norman and Arcement, Julie and Huang, Yiyun and Ogden, R. Todd and Van Heertum, Ronald L and Arango, Victoria and Mann, J. John
The American journal of psychiatry, ISSN 0002-953X, 01/2006, Volume 163, Issue 1, pp. 48 - 51
Life Sciences & Biomedicine | Psychiatry | Science & Technology | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | Depression | Medical sciences | Brain - diagnostic imaging | Gene Expression | Age Factors | Isoquinolines | Depressive Disorder, Major - metabolism | Gene Frequency | Humans | Genotype | Male | Positron-Emission Tomography | Depressive Disorder, Major - diagnostic imaging | Promoter Regions, Genetic - genetics | Polymorphism, Genetic | Brain - metabolism | Serotonin Plasma Membrane Transport Proteins - metabolism | Phenotype | Serotonin Plasma Membrane Transport Proteins - genetics | Depressive Disorder, Major - genetics | Alleles | Adult | Female | Carbon Radioisotopes | Research | Serotonin | Neurological research | Depression, Mental | Psychiatric research | Brain | Physical examinations | Neurotransmitters | Effects | Mental depression | Gene expression | Binding sites | Polymorphism | Index Medicus | Abridged Index Medicus
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4. Full Text Central Serotonin Transporter Availability Measured with [ 123I]β-CIT SPECT in Relation to Serotonin Transporter Genotype
by Van Dyck, Christopher H and Malison, Robert T and Staley, Julie K and Jacobsen, Leslie K and Seibyl, John P and Laruelle, Marc and Baldwin, Ronald M and Innis, Robert B and Gelernter, Joel
The American journal of psychiatry, ISSN 0002-953X, 03/2004, Volume 161, Issue 3, pp. 525 - 531
Life Sciences & Biomedicine | Psychiatry | Science & Technology | Biological and medical sciences | Medical sciences | Neuropharmacology | Serotoninergic system | Neurotransmitters. Neurotransmission. Receptors | Pharmacology. Drug treatments | Membrane Glycoproteins - analysis | Brain - diagnostic imaging | Iodine Radioisotopes | Humans | Middle Aged | Tomography, Emission-Computed, Single-Photon | Male | Reference Values | Serotonin Plasma Membrane Transport Proteins | Promoter Regions, Genetic - genetics | Aged, 80 and over | Adult | Female | Carrier Proteins - analysis | Tandem Repeat Sequences - genetics | Gene Frequency | Genotype | Nerve Tissue Proteins | Cocaine - analogs & derivatives | Membrane Glycoproteins - genetics | Carrier Proteins - genetics | Membrane Transport Proteins | Adolescent | Alleles | Brain Mapping | Polymorphism, Genetic - genetics | Aged | Index Medicus | Abridged Index Medicus
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5. Full Text Integrating the monoamine, neurotrophin and cytokine hypotheses of depression - A central role for the serotonin transporter?
by Haase, Jana and Brown, Eric
Pharmacology & therapeutics (Oxford), ISSN 0163-7258, 2015, Volume 147, pp. 1 - 11
Neuroplasticity | Pro-inflammatory cytokines | Depression | Brain-derived neurotrophic factor | Serotonin transporter | Antidepressants | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Antidepressive Agents - therapeutic use | Serotonin Plasma Membrane Transport Proteins - metabolism | Serotonin Uptake Inhibitors - metabolism | Depression - drug therapy | Depression - metabolism | Animals | Cytokines - metabolism | Humans | Serotonin Uptake Inhibitors - therapeutic use | Nerve Growth Factors - metabolism | Biogenic Monoamines - metabolism | Antidepressive Agents - metabolism | Phenols | Serotonin uptake inhibitors | Serotonin | Cytokines | Depression, Mental | Index Medicus
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6. Full Text Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression: A Meta-analysis
by Risch, Neil and Herrell, Richard and Lehner, Thomas and Liang, Kung-Yee and Eaves, Lindon and Hoh, Josephine and Griem, Andrea and Kovacs, Maria and Ott, Jurg and Merikangas, Kathleen Ries
JAMA : the journal of the American Medical Association, ISSN 0098-7484, 06/2009, Volume 301, Issue 23, pp. 2462 - 2471
Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | General aspects | Miscellaneous | Psychology. Psychoanalysis. Psychiatry | Adult and adolescent clinical studies | Psychopathology. Psychiatry | Mood disorders | Biological and medical sciences | Depression | Medical sciences | Stress, Psychological - genetics | Serotonin Plasma Membrane Transport Proteins - genetics | Depressive Disorder, Major - genetics | Humans | Life Change Events | Risk Factors | Female | Genotype | Male | Studies | Genotype & phenotype | Mental depression | Stress | Meta-analysis | Depressive Disorders | Neurotransmitters | Multiple Traumatic Events | Predisposition | Survivors | Genetic Markers | Meta Analysis | Females | Males | Stressors | Index Medicus | Abridged Index Medicus
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7. Full Text Antidepressant specificity of serotonin transporter suggested by three LeuT-SSRI structures
by Karpowich, Nathan K and Wang, Da-Neng and Reith, Maarten E A and Zhen, Juan and Law, Christopher J and Zhou, Zheng
Nature structural & molecular biology, ISSN 1545-9993, 06/2009, Volume 16, Issue 6, pp. 652 - 657
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amino Acid Transport Systems, Neutral - chemistry | Cell Line | Fluoxetine - pharmacology | Sertraline - pharmacology | Models, Chemical | Humans | Serotonin Uptake Inhibitors - chemistry | Amino Acid Transport Systems, Neutral - metabolism | Crystallography, X-Ray - methods | Serotonin Plasma Membrane Transport Proteins - chemistry | Serotonin Plasma Membrane Transport Proteins - genetics | Norepinephrine - metabolism | Antidepressive Agents, Tricyclic - pharmacology | Protein Binding | Mutation | Drug Evaluation, Preclinical | Serotonin Uptake Inhibitors - pharmacology | Binding Sites | Dopamine - metabolism | Physiological aspects | Serotonin uptake inhibitors | Research | Carrier proteins | Properties | Drug synergism | Neurotransmitters | Molecular biology | Antidepressants | Binding sites | Crystal structure | Index Medicus
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8. Full Text X-ray structures and mechanism of the human serotonin transporter
by Coleman, Jonathan A and Green, Evan M and Gouaux, Eric and Argonne National Lab. (ANL), Argonne, IL (United States)
Nature (London), ISSN 0028-0836, 04/2016, Volume 532, Issue 7599, pp. 334 - 339
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Citalopram - pharmacology | Humans | Protein Conformation - drug effects | Crystallography, X-Ray | Dopamine Plasma Membrane Transport Proteins - chemistry | Structure-Activity Relationship | Antidepressive Agents - metabolism | Citalopram - metabolism | Serotonin Plasma Membrane Transport Proteins - chemistry | Extracellular Space - metabolism | Antidepressive Agents - chemistry | Protein Binding - drug effects | Drug Design | Antidepressive Agents - pharmacology | Protein Stability | Allosteric Regulation - drug effects | Ions - chemistry | Serotonin Plasma Membrane Transport Proteins - immunology | Allosteric Site - drug effects | Models, Molecular | Ions - metabolism | Paroxetine - metabolism | Serotonin Plasma Membrane Transport Proteins - metabolism | Citalopram - chemistry | Intracellular Space - metabolism | Serotonin - metabolism | Ligands | Immunoglobulin Fab Fragments - immunology | Paroxetine - pharmacology | Paroxetine - chemistry | Drug metabolism | Paroxetine | Physiological research | Research | Serotonin | Binding sites (Biochemistry) | X rays | Mutation | Antidepressants | Binding sites | Index Medicus | X-ray crystallography | Transporters in the nervous system | BASIC BIOLOGICAL SCIENCES | Membrane proteins
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