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index medicus (306) 306
animals (302) 302
humans (264) 264
mice (231) 231
male (151) 151
serpin e2 (145) 145
serpin e2 - metabolism (120) 120
female (119) 119
serpin e2 - genetics (112) 112
mice, inbred c57bl (102) 102
expression (99) 99
protease nexins (90) 90
biochemistry & molecular biology (84) 84
mice, knockout (79) 79
serpins - metabolism (75) 75
cell biology (70) 70
serpins - genetics (62) 62
cells, cultured (60) 60
gene expression (58) 58
amyloid beta-protein precursor (57) 57
plasminogen-activator inhibitor-1 (57) 57
receptors, cell surface (52) 52
thrombin (49) 49
middle aged (47) 47
rats (47) 47
rna, messenger - metabolism (47) 47
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analysis (46) 46
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hematology (45) 45
research (45) 45
inflammation (44) 44
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cells (40) 40
genetic aspects (39) 39
pai-1 (39) 39
research article (39) 39
article (37) 37
cell line, tumor (37) 37
abridged index medicus (36) 36
peripheral vascular disease (36) 36
physiological aspects (36) 36
proteins (36) 36
adult (33) 33
gene expression regulation (33) 33
physiology (33) 33
multidisciplinary sciences (32) 32
cell line (31) 31
apoptosis (30) 30
carrier proteins - metabolism (30) 30
fibrosis (30) 30
receptors, cell surface - metabolism (30) 30
endocrinology & metabolism (29) 29
plasminogen activator inhibitor 1 - metabolism (29) 29
plasminogen-activator (29) 29
angiogenesis (28) 28
neurosciences (28) 28
protease nexin-1 (28) 28
fibroblasts - metabolism (27) 27
glia-derived nexin (27) 27
rna, messenger - genetics (27) 27
serpins (27) 27
cancer (26) 26
genes (26) 26
oxidative stress (26) 26
phenotype (26) 26
proteases (26) 26
receptors, cell surface - genetics (26) 26
respiratory system (26) 26
biology (25) 25
carrier proteins - genetics (25) 25
in-vivo (25) 25
medicine (25) 25
gene-expression (24) 24
health aspects (24) 24
immunohistochemistry (24) 24
obesity (24) 24
oncology (24) 24
plasminogen activator inhibitor-1 (24) 24
risk factors (24) 24
rodents (24) 24
amyloid beta-protein precursor - genetics (23) 23
cell proliferation (23) 23
development and progression (23) 23
fibrinolysis (23) 23
genetics & heredity (23) 23
plasminogen activator inhibitor 1 - genetics (23) 23
amyloid beta-protein precursor - metabolism (22) 22
blotting, western (22) 22
pulmonary disease, chronic obstructive - genetics (22) 22
serpin e2 - biosynthesis (22) 22
serpins - physiology (22) 22
thrombin - metabolism (22) 22
medicine, research & experimental (21) 21
metastasis (21) 21
molecular sequence data (21) 21
nerve growth factors - metabolism (21) 21
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Oncotarget, ISSN 1949-2553, 2016, Volume 7, Issue 50, pp. 82289 - 82304
The extracellular serine protease inhibitor serpinE2 is overexpressed in breast cancer and has been shown to foster metastatic spread. Here, we investigated... 
Serine protease inhibitors | Collagen I | Tumor associated macrophages | Breast cancer | Metastasis | MIGRATION | tumor associated macrophages | PROTECTION | breast cancer | CELL BIOLOGY | INVASION | metastasis | collagen I | GROWTH | BINDING-SITE | DEGRADATION | serine protease inhibitors | PROTEASE NEXIN-1 | INHIBITOR | RECEPTOR-RELATED PROTEIN-1 | GLIA-DERIVED NEXIN | Serpin E2 - antagonists & inhibitors | Humans | Lung Neoplasms - metabolism | Extracellular Matrix - metabolism | Tumor Microenvironment | Extracellular Signal-Regulated MAP Kinases - metabolism | Breast Neoplasms - metabolism | Tissue Inhibitor of Metalloproteinase-1 - metabolism | Transfection | Lung Neoplasms - secondary | RNA Interference | Female | Antineoplastic Agents - pharmacology | Chemokine CCL2 - metabolism | Lung Neoplasms - genetics | Collagen Type I - metabolism | Macrophages - pathology | Signal Transduction | Neoplasm Invasiveness | Mice, SCID | Breast Neoplasms - drug therapy | Xenograft Model Antitumor Assays | Cell Movement - drug effects | Macrophages - metabolism | Phenotype | Serpin E2 - genetics | Animals | Breast Neoplasms - genetics | Lung Neoplasms - prevention & control | Breast Neoplasms - pathology | Cell Line, Tumor | Macrophages - drug effects | Mice, Inbred BALB C | Extracellular Matrix - pathology | Serpin E2 - metabolism
Journal Article
Biogerontology, ISSN 1389-5729, 2013, Volume 14, Issue 3, pp. 303 - 323
During ageing skeletal muscles undergo a process of structural and functional remodelling that leads to sarcopenia, a syndrome characterized by loss of muscle... 
Life Sciences | Sarcopenia | FoxO | Geriatrics/Gerontology | Ageing | mTOR | IGF1 | Akt | Developmental Biology | Cell Biology | LIFE-SPAN | IGF-I | ALPHA-V-BETA-3 INTEGRIN | PLASMINOGEN-ACTIVATOR INHIBITOR-1 | GERIATRICS & GERONTOLOGY | GROWTH-HORMONE | MESSENGER-RNA | GENETIC-DETERMINANTS | FAST-TWITCH | CELL-CYCLE | S6 KINASE | Microtubule-Associated Proteins - genetics | SKP Cullin F-Box Protein Ligases - genetics | Humans | SKP Cullin F-Box Protein Ligases - physiology | Male | Forkhead Transcription Factors - physiology | Ubiquitin-Protein Ligases - physiology | Tripartite Motif Proteins | Young Adult | Aged, 80 and over | Adult | Female | Mice, Inbred DBA | Models, Animal | TOR Serine-Threonine Kinases - physiology | Muscle Proteins - physiology | Serpin E2 - physiology | Mice, Inbred C57BL | Mice, Transgenic | Proto-Oncogene Proteins c-akt - physiology | Muscle, Skeletal - physiology | Mice, Knockout | Microtubule-Associated Proteins - physiology | Muscle Proteins - genetics | Autophagy-Related Protein 7 | Sarcopenia - physiopathology | Serpin E2 - genetics | Animals | Aging - physiology | Insulin-Like Growth Factor I - physiology | Adolescent | Signal Transduction - physiology | Aged | Forkhead Box Protein O1 | Mice | Ubiquitin-Protein Ligases - genetics | Ubiquitin | Muscles | Ligases | Proteolysis | Analysis | SKP Cullin F-Box Protein Ligases | Muscle Proteins | Aging | Serpin E2 | Signal Transduction | Biochemistry, Molecular Biology | Microtubule-Associated Proteins | Insulin-Like Growth Factor I | Proto-Oncogene Proteins c-akt | Ubiquitin-Protein Ligases | TOR Serine-Threonine Kinases | Muscle, Skeletal | Forkhead Transcription Factors | Clinical Medicine | Neurology | Neurologi | Medical and Health Sciences | Medicin och hälsovetenskap | Clinical Neurophysiology | Klinisk neurofysiologi | Klinisk medicin
Journal Article
Circulation, ISSN 0009-7322, 03/2011, Volume 123, Issue 12, pp. 1326 - 1334
Journal Article
Blood, ISSN 0006-4971, 08/2011, Volume 118, Issue 8, pp. 2313 - 2321
Journal Article
American Journal of Physiology - Lung Cellular and Molecular Physiology, ISSN 1040-0605, 2015, Volume 308, Issue 4, pp. L344 - L357
Pathological fibrosis is driven by a feedback loop in which the fibrotic extracellular matrix is both a cause and consequence of fibroblast activation.... 
Plasminogen activator inhibitor 1 | Extracellular matrix | Mechanotransduction | Hippo | Idiopathic pulmonary fibrosis | LUNG | DOMAIN | PHYSIOLOGY | mechanotransduction | HIPPO PATHWAY | idiopathic pulmonary fibrosis | TRANSCRIPTIONAL COACTIVATOR | plasminogen activator inhibitor 1 | GROWTH-FACTOR-BETA | MECHANICAL MEMORY | MATRIX STIFFNESS | INHIBITION | RESPIRATORY SYSTEM | DIFFERENTIATION | IDIOPATHIC PULMONARY-FIBROSIS | extracellular matrix | NIH 3T3 Cells | Humans | Male | Intracellular Signaling Peptides and Proteins - metabolism | Pulmonary Fibrosis - genetics | Phosphoproteins - metabolism | Serpin E2 - biosynthesis | Gene Knockdown Techniques | Female | Lung - metabolism | Pulmonary Fibrosis - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Intracellular Signaling Peptides and Proteins - genetics | Mechanotransduction, Cellular - genetics | Fibroblasts - metabolism | Lung - pathology | Pulmonary Fibrosis - pathology | Phosphoproteins - genetics | Fibroblasts - pathology | Plasminogen Activator Inhibitor 1 - biosynthesis | Serpin E2 - genetics | Animals | Transforming Growth Factor beta - genetics | Adaptor Proteins, Signal Transducing - genetics | Mice, Inbred NOD | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Transforming Growth Factor beta - metabolism | Transcriptional coactivators | Fibroblasts | Genetic aspects | Pulmonary fibrosis | Health aspects | Oncogenes | Call for Papers
Journal Article
Biology of Reproduction, ISSN 0006-3363, 03/2011, Volume 84, Issue 3, pp. 514 - 525
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2013, Volume 33, Issue 7, pp. 1647 - 1654
Journal Article
FASEB Journal, ISSN 0892-6638, 06/2017, Volume 31, Issue 6, pp. 2625 - 2637
Adhesive small bowel obstruction remains a common problem for surgeons. After surgery, platelet aggregation contributes to coagulation cascade and fibrin clot... 
PAI-1 | Plasminogen activator | Small bowel obstruction | Epidermal growth factor | Mesothelial cell | MIGRATION | FIBROSIS | MATRIX | MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | plasminogen activator | PREVENTION | RELEASE | small bowel obstruction | mesothelial cell | MESOTHELIAL CELLS | CELL BIOLOGY | PAI-1 EXPRESSION | BIOLOGY | epidermal growth factor | Macrophages - physiology | Receptor, Epidermal Growth Factor - genetics | Serpin E2 - antagonists & inhibitors | Signal Transduction | Tissue Plasminogen Activator - metabolism | Mice, Inbred C57BL | Postoperative Complications - prevention & control | Gene Expression Regulation - physiology | Cetuximab - pharmacology | CD11b Antigen | Piperazines - therapeutic use | Tissue Plasminogen Activator - genetics | Epidermal Growth Factor | Cell Movement - drug effects | Receptor, Epidermal Growth Factor - metabolism | Serpin E2 - genetics | Tissue Adhesions - pathology | Animals | Tissue Adhesions - metabolism | para-Aminobenzoates - therapeutic use | RAW 264.7 Cells | Mice | Cell Migration Assays | Serpin E2 - metabolism | Macrophages | Bisphosphonates | Plasmin | Clotting | t-Plasminogen activator | Bleeding | Recruitment | Cell activation | Proteolysis | Intestine | Surgery | Inhibition | Refueling | Medical personnel | Secretion | Polyamide-imides | Pharmacology | Platelet aggregation | Fibrinolysis | Adhesion | Clodronic acid | Gauze | Fibrin | Signaling | Adhesives | Inhibitors | Plasminogen activator inhibitors | Peritoneum
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