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The New England Journal of Medicine, ISSN 0028-4793, 09/2015, Volume 373, Issue 12, pp. 1106 - 1114
A two-step process, in which circulating levels of amyloid P are reduced and then anti–serum amyloid P antibody is given to activate macrophage clearance... 
MEDICINE, GENERAL & INTERNAL | CARDIOVASCULAR MAGNETIC-RESONANCE | QUANTIFICATION | VOLUME | SCINTIGRAPHY | TISSUE | LIVER | SYSTEMIC AMYLOIDOSIS | AL AMYLOIDOSIS | PHARMACOLOGICAL DEPLETION | Liver - pathology | Serum Amyloid P-Component - immunology | Humans | Immunoglobulin G | Middle Aged | Antibodies, Monoclonal - adverse effects | Carboxylic Acids - pharmacokinetics | Pyrrolidines - administration & dosage | Pyrrolidines - adverse effects | Amyloidosis - diagnostic imaging | Dose-Response Relationship, Drug | Carboxylic Acids - adverse effects | Liver - drug effects | Liver - diagnostic imaging | Adult | Carboxylic Acids - administration & dosage | Serum Amyloid P-Component - antagonists & inhibitors | Immunoglobulin Light-chain Amyloidosis | Pyrrolidines - pharmacokinetics | Antibodies, Monoclonal - pharmacokinetics | Amyloidosis - drug therapy | Serum Amyloid P-Component - analysis | Antibodies, Monoclonal - administration & dosage | Radionuclide Imaging | Aged | Infusions, Intravenous | Monoclonal antibodies | Care and treatment | Amyloidosis | Dosage and administration | Immunoglobulins | Kidneys | Mortality | Liver | Inflammation | Scintigraphy | Macrophages | SAP protein | Patients | Lymph nodes | Atrophy | Proteins | Magnetic resonance imaging | Rodents | Giant cells | Drug therapy | Drug dosages | Amyloid P component
Journal Article
Journal Article
Nature Immunology, ISSN 1529-2908, 04/2010, Volume 11, Issue 4, pp. 328 - 334
Journal Article
Nature, ISSN 0028-0836, 07/1999, Volume 400, Issue 6740, pp. 173 - 177
Journal Article
Journal of Clinical Immunology, ISSN 0271-9142, 1/2008, Volume 28, Issue 1, pp. 1 - 13
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2015, Volume 112, Issue 27, pp. 8385 - 8390
Fibrosis is caused by scar tissue formation in internal organs and is associated with 45% of deaths in the United States. Two closely related human serum... 
DC-SIGN | IL-10 | Pentraxin | Fibrosis | Serum amyloid P | SERUM AMYLOID-P | CELLS | FC-GAMMA RECEPTORS | MECHANISM | HUMAN MACROPHAGES | MULTIDISCIPLINARY SCIENCES | MOUSE | pentraxin | serum amyloid P | INDUCED PULMONARY-FIBROSIS | GENE-EXPRESSION | fibrosis | Serum Amyloid P-Component - immunology | Humans | Lectins, C-Type - immunology | Cell Adhesion Molecules - immunology | Receptors, IgG - metabolism | Lectins, C-Type - metabolism | Receptors, IgG - genetics | C-Reactive Protein - metabolism | HEK293 Cells | Interleukin-10 - metabolism | Lung - metabolism | Pulmonary Fibrosis - metabolism | Neutrophils - metabolism | Macrophages - immunology | Lung - pathology | Mice, Inbred C57BL | Neutrophils - drug effects | Cells, Cultured | Neutrophils - immunology | Pulmonary Fibrosis - immunology | Receptors, Cell Surface - metabolism | Receptors, IgG - immunology | Protein Binding - immunology | Cell Adhesion Molecules - metabolism | Receptors, Cell Surface - immunology | Blotting, Western | Mice, Knockout | Immunity, Innate - immunology | Microscopy, Confocal | Macrophages - metabolism | Animals | Pulmonary Fibrosis - prevention & control | Serum Amyloid P-Component - metabolism | Thiazoles - pharmacology | Interleukin-10 - immunology | C-Reactive Protein - immunology | Lung - immunology | Measurement | C-reactive protein | Diagnosis | Drug therapy | Health aspects | Risk factors | Biological Sciences
Journal Article