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Tetrahedron, ISSN 0040-4020, 04/2015, Volume 71, Issue 16, pp. 2382 - 2386
The first total synthesis of (−)-5,6- -germacrane lactone has been achieved. The synthetic highlight of our approach includes sp –sp Suzuki–Miyaura cross... 
Suzuki–Miyaura coupling | Natural product | Germacranes | One-pot regioselective bromination | Total synthesis | Suzuki-Miyaura coupling | LINEAR SESQUITERPENE LACTONES | DBU CONDITIONS | REVISION | ETHERS | BIOSYNTHESIS | CHEMISTRY, ORGANIC | ALPHA-METHYLENATION | Zirconium | Synthesis | Organic compounds
Journal Article
FEBS Letters, ISSN 0014-5793, 2006, Volume 580, Issue 5, pp. 1411 - 1416
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 08/2012, Volume 134, Issue 32, pp. 13348 - 13356
Dyotropic rearrangements of fused, tricyclic β-lactones are described that proceed via unprecedented stereospecific, 1,2-acyl migrations delivering bridged,... 
ISOSTERE | SYMMETRY CONTROLLED REACTIONS | CURCUMANOLIDE-A | REAGENTS | ENANTIOSELECTIVE SYNTHESIS | ABSOLUTE-CONFIGURATION | KETO ACIDS | CARBONYL-COMPOUNDS | CHEMISTRY, MULTIDISCIPLINARY | DISCOVERY | BUTYROLACTONES | Molecular Structure | Sesquiterpenes - chemistry | Cyclization | Lactones - chemistry
Journal Article
06/2018, ISBN 3319782738, 379
This book addresses chemical and biological aspects related to sesquiterpene lactones (STLs). Experts in different fields have been invited to contribute on... 
Sesquiterpene lactones | Pharmaceutical chemistry | Chemistry, Organic
eBook
Cell Biology and Toxicology, ISSN 0742-2091, 12/2015, Volume 31, Issue 6, pp. 295 - 305
Medicinal plant extracts have been widely used for cancer treatment. Gaillardin is a natural sesquiterpene lactone that has recently been reported to have... 
Life Sciences | Biochemistry, general | Gaillardin | Sesquiterpene lactone | Breast cancer | Mitochondrial pathway | Pharmacology/Toxicology | Cell Biology | Apoptosis | Caspase 6 - metabolism | Sesquiterpenes - isolation & purification | Caspase 9 - genetics | Caspase 9 - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Membrane Potential, Mitochondrial - drug effects | Lactones - pharmacology | Reactive Oxygen Species - agonists | Proto-Oncogene Proteins c-bcl-2 - metabolism | Iran | MCF-7 Cells | Caspase 3 - genetics | Female | Gene Expression Regulation, Neoplastic - drug effects | bcl-2-Associated X Protein - genetics | Fibroblasts - metabolism | Inula - chemistry | Cell Line | Cell Survival - drug effects | Lactones - isolation & purification | Signal Transduction | bcl-2-Associated X Protein - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Caspase 6 - genetics | Fibroblasts - drug effects | Cell Line, Tumor | Cell Proliferation - drug effects | Fibroblasts - cytology | Sesquiterpenes - pharmacology | Antineoplastic Agents, Phytogenic - pharmacology | Proto-Oncogene Proteins c-bcl-2 - genetics | Plants, Medicinal | Antineoplastic Agents, Phytogenic - isolation & purification | Complications and side effects | Care and treatment | Development and progression | Genetic aspects | Research | Herbal medicine | Proteins | Mitochondria
Journal Article
Journal Article
Journal Article
PEST MANAGEMENT SCIENCE, ISSN 1526-498X, 03/2016, Volume 72, Issue 3, pp. 489 - 496
BACKGROUNDLactones are well known for their biological activity. Grosheimin and repin are potent deterrents against storage pests. The unsaturated lactones... 
SYSTEM | POTENT | AGRONOMY | HALOLACTONES | anisaldehyde derivatives | antifeedant activity | INULA | dehalogenation | DERIVATIVES | ENTOMOLOGY | antibacterial lactones | SESQUITERPENE LACTONES | Antibacterial agents
Journal Article
PLANT PHYSIOLOGY, ISSN 0032-0889, 11/2019, Volume 181, Issue 3, pp. 945 - 960
Adaptive evolution of enzymes benefits from catalytic promiscuity. Sesquiterpene lactones (STLs) have diverged extensively in the Asteraceae, and studies of... 
SYNTHASE | ANTIMALARIAL-DRUG PRECURSOR | ISOPRENOID-BIOSYNTHESIS | EVOLUTIONARY | PROTEIN STABILITY | ACID | ARTEMISIA-ANNUA | CLONING | REVEAL | EXPRESSION | PLANT SCIENCES | Oxidases | Physiological aspects | Amino acids | Sesquiterpenes | Lactones | Promiscuity
Journal Article
Anti-Cancer Drugs, ISSN 0959-4973, 10/2012, Volume 23, Issue 9, pp. 883 - 896
Journal Article