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Nature (London), ISSN 1476-4687, 2016, Volume 537, Issue 7622, pp. 694 - 697
Journal Article
The Plant cell, ISSN 1532-298X, 2012, Volume 24, Issue 6, pp. 2635 - 2648
Arabidopsis thaliana flowers emit volatile terpenes, which may function in plant—insect interactions. Here, we report that Arabidopsis MYC2, a basic... 
Transcriptional regulatory elements | Transcription factors | Inflorescences | Sesquiterpenes | Genes | Biosynthesis | Gene expression regulation | Plants | Terpenes | Plant cells | TRANSCRIPTION FACTORS | SEED-GERMINATION | PLANT VOLATILES | BIOCHEMISTRY & MOLECULAR BIOLOGY | GIBBERELLIN | FUNCTIONAL-CHARACTERIZATION | PLANT SCIENCES | CELL BIOLOGY | ARTEMISIA-ANNUA | TERPENE SYNTHASES | ABSCISIC-ACID | JASMONATE | (E)-BETA-OCIMENE SYNTHASE | Sesquiterpenes - metabolism | Alkyl and Aryl Transferases - metabolism | Arabidopsis Proteins - metabolism | Alkyl and Aryl Transferases - genetics | Gibberellins - metabolism | Light | Gene Expression Regulation, Plant | Repressor Proteins - metabolism | Promoter Regions, Genetic | Arabidopsis Proteins - genetics | Arabidopsis - drug effects | Inflorescence - genetics | Plants, Genetically Modified - genetics | Signal Transduction | Repressor Proteins - genetics | Cyclopentanes - pharmacology | Arabidopsis - metabolism | Arabidopsis - genetics | Oxylipins - metabolism | Two-Hybrid System Techniques | Plants, Genetically Modified - metabolism | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - genetics | Inflorescence - metabolism | Oxylipins - pharmacology | Gibberellins - pharmacology | Basic Helix-Loop-Helix Leucine Zipper Transcription Factors - metabolism | Cyclopentanes - metabolism | Mutation | Proteins | Arabidopsis | Plant genetics | Physiological aspects | Genetic aspects | Research | Gene expression
Journal Article
Scientific reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, p. 23240
Sepsis is the principal cause of fatality in the intensive care units worldwide. It involves uncontrolled inflammatory response resulting in multi-organ... 
CELLS | SHOCK | ACTIVATION | RECOGNITION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | IL-10 PRODUCTION | PROINFLAMMATORY CYTOKINES | INTERVENTION | SESQUITERPENE LACTONES | SEVERE SEPSIS | Tumor Necrosis Factor-alpha - metabolism | Sepsis - etiology | Sepsis - prevention & control | Apoptosis - drug effects | Monocytes - cytology | Humans | Monocytes - metabolism | NF-kappa B - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Interleukin-1beta - metabolism | Interleukin-10 - metabolism | Female | Chemokine CCL2 - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Interleukin-6 - metabolism | Cell Line | Sesquiterpenes, Guaiane - pharmacology | Lung - pathology | Lipopolysaccharides - toxicity | Anti-Inflammatory Agents - pharmacology | Liver - metabolism | Mice, Inbred C57BL | Macrophages - cytology | Toll-Like Receptor 4 - metabolism | Monocytes - drug effects | Macrophages - metabolism | Animals | Signal Transduction - drug effects | Macrophages - drug effects | RAW 264.7 Cells | Cell Proliferation - drug effects | Mice | Mitogen-Activated Protein Kinases - metabolism | Liver | AKT protein | Arthritis | Kinases | Macrophages | Immunosuppressive agents | Lipopolysaccharides | Interleukin 6 | Intensive care units | Cell activation | Intestine | Rodents | Gram-negative bacteria | Peritonitis | Dendritic cells | Cell walls | MAP kinase | 1-Phosphatidylinositol 3-kinase | Dextran | Monocytes | Protein kinase | Interleukin 10 | Sepsis | Interferon | Colitis | Monocyte chemoattractant protein 1 | Cancer
Journal Article
Nature Chemical Biology, ISSN 1552-4450, 11/2015, Volume 11, Issue 11, pp. 837 - 839
Phytoalexins are abundant in edible crucifers and have important biological activities, yet no dedicated gene for their biosynthesis is known. Here, we report... 
ARABIDOPSIS-THALIANA | INHIBITION | PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENES | STRESS METABOLITES | BRASSICACEAE | YEAST EXPRESSION | BRASSININ | GLUCOSINOLATE METABOLISM | CAMALEXIN | Microsomes - metabolism | Thiazoles - metabolism | Sesquiterpenes - metabolism | Thiocarbamates - metabolism | Brassica rapa - enzymology | Cytochrome P-450 Enzyme System - metabolism | Molecular Sequence Data | Isoenzymes - chemistry | Brassica rapa - genetics | RNA, Messenger - metabolism | Indoles - metabolism | Vegetables - chemistry | Isoenzymes - metabolism | Plant Proteins - chemistry | Base Sequence | Escherichia coli - metabolism | Vegetables - metabolism | Plant Proteins - metabolism | Spiro Compounds - chemistry | Plant Leaves - chemistry | Recombinant Proteins - metabolism | Gene Expression | Biocatalysis | Sesquiterpenes - chemistry | Isoenzymes - genetics | RNA, Messenger - genetics | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Thiocarbamates - chemistry | Brassicaceae - genetics | Microsomes - chemistry | Plant Proteins - genetics | Cytochrome P-450 Enzyme System - chemistry | Cyclization | Plant Leaves - metabolism | Escherichia coli - genetics | Cytochrome P-450 Enzyme System - genetics | Thiazoles - chemistry | High-Throughput Nucleotide Sequencing | Kinetics | Indoles - chemistry | Brassicaceae - enzymology | Spiro Compounds - metabolism | Genetics | Biosynthesis | Biochemistry | Metabolites
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2009, Volume 106, Issue 26, pp. 10865 - 10870
We identified a cis-prenyltransferase gene, neryl diphosphate synthase 1 (NDPS1). that is expressed in cultivated tomato (Solanum lycopersicum) cultivar M82... 
Enzymes | Sesquiterpenes | Genes | Monoterpenes | Trichomes | Biosynthesis | Diphosphates | Plants | Terpenes | Chromosomes | Terpene synthases | Specialized metabolism | Plant biochemistry | Cis-prenyltransferases | Biochemical diversity | ARABIDOPSIS-THALIANA | plant biochemistry | SAGE SALVIA-OFFICINALIS | MULTIDISCIPLINARY SCIENCES | DOLICHOL BIOSYNTHESIS | specialized metabolism | cis-prenyltransferases | terpene synthases | PYROPHOSPHATE SYNTHETASE | biochemical diversity | LYCOPERSICON-ESCULENTUM | CIS-PRENYLTRANSFERASE | CDNA ISOLATION | SESQUITERPENE BIOSYNTHESIS | KEY ENZYME | BACTERIAL EXPRESSION | Diphosphates - metabolism | Polyisoprenyl Phosphates - chemistry | Gas Chromatography-Mass Spectrometry | Alkyl and Aryl Transferases - metabolism | DNA, Complementary - genetics | Molecular Sequence Data | Substrate Specificity | Lycopersicon esculentum - enzymology | Organophosphorus Compounds - metabolism | Plant Epidermis - metabolism | Hemiterpenes - metabolism | Dimethylallyltranstransferase - genetics | Alkyl and Aryl Transferases - genetics | Cloning, Molecular | Gene Expression Regulation, Plant | Lycopersicon esculentum - genetics | Molecular Structure | Plant Proteins - metabolism | Diterpenes - metabolism | Plant Epidermis - enzymology | Diterpenes - chemistry | Hemiterpenes - chemistry | Lycopersicon esculentum - metabolism | Gene Library | Organophosphorus Compounds - chemistry | Biosynthetic Pathways | Reverse Transcriptase Polymerase Chain Reaction | Polyisoprenyl Phosphates - metabolism | Sequence Analysis, DNA | Diphosphates - chemistry | Plant Proteins - genetics | Monoterpenes - metabolism | Dimethylallyltranstransferase - metabolism | Monoterpenes - analysis | Monoterpenes - chemistry | DNA, Complementary - chemistry | Kinetics | Tomatoes | Chemical properties | Research | Pyrophosphates | Biological Sciences
Journal Article
The Plant cell, ISSN 1040-4651, 12/2003, Volume 15, Issue 12, pp. 2866 - 2884
.... The active terpenoid metabolism in wild-type Arabidopsis provoked us to conduct an additional set of experiments in which transgenic Arabidopsis overexpressing two different terpene synthases were generated... 
Leaves | Terpenoids | Sesquiterpenes | Monoterpenes | Biosynthesis | Plants | Flowers | Metabolism | Transgenic plants | Plastids | isoprenoid biosynthesis | sesquiterpene cyclase gene | cdna isolation | glandular trichomes | thaliana | diphosphate synthase | monoterpene biosynthesis | linalool synthase gene | functional expression | s-linalool | SESQUITERPENE CYCLASE GENE | S-LINALOOL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLANT SCIENCES | CELL BIOLOGY | CDNA ISOLATION | ISOPRENOID BIOSYNTHESIS | THALIANA | FUNCTIONAL EXPRESSION | DIPHOSPHATE SYNTHASE | LINALOOL SYNTHASE GENE | GLANDULAR TRICHOMES | MONOTERPENE BIOSYNTHESIS | Aphids - growth & development | Sesquiterpenes - metabolism | Alkyl and Aryl Transferases - metabolism | Terpenes - chemistry | Terpenes - metabolism | Alkyl and Aryl Transferases - genetics | Volatilization | Gene Expression Regulation, Plant | Plant Proteins - metabolism | Chicory - metabolism | Hydroxylation | Plants, Genetically Modified - genetics | Sesquiterpenes, Germacrane - metabolism | Glycosylation | Polyisoprenyl Phosphates - metabolism | Chloroplasts - metabolism | Arabidopsis - metabolism | Arabidopsis - genetics | Plant Proteins - genetics | Animals | Plants, Genetically Modified - metabolism | Monoterpenes - metabolism | Plants, Genetically Modified - parasitology | Monoterpenes - chemistry | Arabidopsis - parasitology | Arabidopsis | Genetically modified plants | Research | FaNES1 gene
Journal Article
Plant biotechnology journal, ISSN 1467-7644, 2017, Volume 15, Issue 9, pp. 1105 - 1119
Summary Many aromatic plants, such as spearmint, produce valuable essential oils in specialized structures called peltate glandular trichomes (PGTs).... 
transcription factor | terpene | spearmint | GPPS | secondary metabolism | R2R3‐MYB | R2R3-MYB | ARABIDOPSIS-THALIANA | TERPENOID BIOSYNTHESIS | FUNCTIONAL-CHARACTERIZATION | HEVEA-BRASILIENSIS | PLANT SCIENCES | AGROBACTERIUM-TUMEFACIENS | ISOPRENOID BIOSYNTHESIS | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | PELTATE GLANDULAR TRICHOMES | GENE FAMILY | MENTHA-SPICATA | LIGNIN BIOSYNTHESIS | Ocimum basilicum - cytology | Diphosphates - metabolism | Sesquiterpenes - metabolism | Mentha spicata - metabolism | Mentha spicata - cytology | Phylogeny | Ocimum basilicum - metabolism | Geranyltranstransferase - genetics | Base Sequence | Plants, Genetically Modified | Gene Expression Regulation, Plant | Ocimum basilicum - genetics | Mentha spicata - genetics | Oils, Volatile - metabolism | Plant Proteins - metabolism | Diterpenes - metabolism | Geranyltranstransferase - metabolism | Amino Acid Sequence | Gene Expression | Tobacco - metabolism | Transcription Factors - genetics | Secondary Metabolism | Tobacco - cytology | Transcription Factors - metabolism | Plant Proteins - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Tobacco - genetics | Monoterpenes - metabolism | Plant Oils - metabolism | RNA sequencing | Arabidopsis thaliana | Genetically modified plants | Cladistic analysis | Analysis | Genetic engineering | Plants | Plant metabolites
Journal Article
ACS Nano, ISSN 1936-0851, 07/2014, Volume 8, Issue 7, pp. 7305 - 7317
Antiangiogenesis has been extensively explored for the treatment of a variety of cancers and certain inflammatory processes. Fumagillin, a mycotoxin produced... 
nitric oxide | autophagy | AMP-activated protein kinase | fumagillin prodrug | angiogenesis | nanotherapy | RHEUMATOID-ARTHRITIS | ACTIVATED PROTEIN-KINASE | ANTIANGIOGENIC NANOTHERAPY | MATERIALS SCIENCE, MULTIDISCIPLINARY | CHEMISTRY, PHYSICAL | NANOSCIENCE & NANOTECHNOLOGY | CHEMISTRY, MULTIDISCIPLINARY | CELL-DEATH | DOUBLE-EDGED-SWORD | MOUSE MODEL | AMPK | ANTIGEN-INDUCED ARTHRITIS | NF-KAPPA-B | Inflammation - pathology | AMP-Activated Protein Kinases - metabolism | Sesquiterpenes - metabolism | Arthritis - metabolism | Male | Prodrugs - metabolism | Nanoparticles | Cyclohexanes - metabolism | Inflammation - metabolism | Inflammation - drug therapy | Arthritis - immunology | Cyclohexanes - chemistry | Nanomedicine | Sesquiterpenes - chemistry | Cytokines - metabolism | Arthritis - pathology | Endothelial Cells - metabolism | Inflammation - immunology | Fatty Acids, Unsaturated - metabolism | Lipase - metabolism | Macrophages - cytology | Enzyme Activation - drug effects | Angiogenesis Inhibitors - metabolism | Animals | Fatty Acids, Unsaturated - chemistry | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | Arthritis - drug therapy | Macrophages - drug effects | Mice | Prodrugs - therapeutic use | Nitric Oxide - metabolism | Prodrugs - pharmacology | Angiogenesis Inhibitors - chemistry | Endothelial Cells - drug effects
Journal Article
Journal of experimental botany, ISSN 0022-0957, 1/2012, Volume 63, Issue 5, pp. 1951 - 1967
Flowers of the kiwifruit species produce a mixture of sesquiterpenes derived from farnesyl diphosphate (FDP) and monoterpenes derived from geranyl diphosphate... 
Enzymes | Terpenoids | Sesquiterpenes | Biosynthesis | Monoterpenes | Plants | Diphosphates | Flowers | Terpenes | Gross domestic product | RESEARCH PAPER | nerolidol | farnesol | Actinidia | terpene | terpene synthase | floral volatiles | kiwifruit | MOLECULAR-BIOLOGY | S-LINALOOL | TERPENOID BIOSYNTHESIS | PHOSPHATE-PATHWAY | PLANT SCIENCES | COA REDUCTASE | REDUCTASE-ACTIVITY | ISOPRENOID BIOSYNTHESIS | HIGHER-PLANTS | SNAPDRAGON FLOWERS | ALPHA-FARNESENE | Diphosphates - metabolism | Farnesol - metabolism | Sesquiterpenes - metabolism | Oils, Volatile - analysis | Flowers - metabolism | Alkyl and Aryl Transferases - metabolism | Molecular Sequence Data | Substrate Specificity | Phylogeny | Recombinant Proteins | Farnesol - analysis | Alkyl and Aryl Transferases - genetics | Sesquiterpenes - analysis | Base Sequence | Oils, Volatile - metabolism | Plant Proteins - metabolism | Actinidia - enzymology | Diterpenes - metabolism | Plant Leaves - enzymology | Flowers - enzymology | Tobacco - metabolism | Actinidia - metabolism | Gene Expression Regulation, Plant - genetics | Polyisoprenyl Phosphates - metabolism | Sequence Analysis, DNA | Arabidopsis - metabolism | Actinidia - genetics | Arabidopsis - genetics | Plant Proteins - genetics | Plant Leaves - genetics | Plant Leaves - metabolism | Tobacco - genetics | Monoterpenes - metabolism | Monoterpenes - analysis | Kinetics | Flowers - genetics | Research Papers
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0169116 - e0169116
Journal Article