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1. Full Text Corrigendum to “MLKL contributes to shikonin-induced glioma cell necroptosis via promotion of chromatinolysis” [Canc. Lett. 467 (2019) 58–71]
by Ding, Ye and He, Chuan and Lu, Shan and Wang, Xuanzhong and Wang, Chongcheng and Wang, Lei and Zhang, Ji and Piao, Meihua and Chi, Guangfan and Luo, Yinan and Sai, Ke and Ge, Pengfei
Cancer letters, ISSN 0304-3835, 03/2020, Volume 472, pp. 183 - 183
Index Medicus
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2. Full Text An improved and practical synthesis route to antiproliferative (±)-shikonin and its O-acyl derivatives
by Ono, Mana and Abe, Shouki and Higai, Koji and Higashi, Shoko and Saito, Setsuo and Saito, Ryota
Synthetic communications, ISSN 0039-7911, 2020
olefin metathesis | O-acyl shikonin | Shikonin | gram-scale synthesis | Physical Sciences | Chemistry | Chemistry, Organic | Science & Technology
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3. Full Text Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line
by Yang, Wei and Liu, Jianhua and Hou, Lin and Chen, Qingmin and Liu, Yahui
Life sciences (1973), ISSN 0024-3205, 01/2021, Volume 265, pp. 118796 - 118796
Glycolysis | Mitochondrial biogenesis | Shikonin | PKM2 | HIF1α | Apoptosis | Index Medicus
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4. Full Text Fabrication of cellulose nanofiber-based functional color indicator film incorporated with shikonin extracted from Lithospermum erythrorhizon root
by Roy, Swarup and Rhim, Jong-Whan
Food hydrocolloids, ISSN 0268-005X, 05/2021, Volume 114
Shikonin | Cellulose nanofiber | Smart packaging | Intelligent color indicator film
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5. Full Text Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis
by Song, Wan and Zhuang, Yibin and Liu, Tao
Phytochemistry (Oxford), ISSN 0031-9422, 07/2020, Volume 175, pp. 112375 - 112375
Lithospermum erythrorhizon | Shikonin | Boraginaceae | Cytochrome P450 monooxygenase | Geranylhydroquinone | Index Medicus
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6. Full Text Shikonin induced necroptosis via reactive oxygen species in the T-47D breast cancer cell line
by Shahsavari, Zahra and Karami-Tehrani, Fatemeh and Salami, Siamak
Asian Pacific journal of cancer prevention : APJCP, ISSN 1513-7368, 2015, Volume 16, Issue 16, pp. 7261 - 7266
Breast cancer | Necroptosis | Shikonin | ROS | Apoptosis
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7. Full Text Pharmacological properties and derivatives of shikonin—A review in recent years
by Guo, Chuanjie and He, Junlin and Song, Xiaominting and Tan, Lu and Wang, Miao and Jiang, Peidu and Li, Yuzhi and Cao, Zhixing and Peng, Cheng
Pharmacological research, ISSN 1043-6618, 11/2019, Volume 149, pp. 104463 - 104463
Derivative | Anticancer | Shikonin | Anti-inflammatory | Wound-healing | Index Medicus
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8. Full Text Shikonin upregulates the expression of drug-metabolizing enzymes and drug transporters in primary rat hepatocytes
by Huang, Chin-Shiu and Chen, Haw-Wen and Lin, Tzu-Yu and Lin, Ai-Hsuan and Lii, Chong-Kuei
Journal of ethnopharmacology, ISSN 0378-8741, 04/2018, Volume 216, pp. 18 - 25
Aryl hydrocarbon receptor | Shikonin | Shikonin (PubChem CID:479503) | NF-E2-related factor | Drug-metabolizing enzymes | Drug transporters | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Integrative & Complementary Medicine | Plant Sciences | Science & Technology | Index Medicus
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9. Full Text Simultaneous Addition of Shikonin and Its Derivatives with Lipopolysaccharide Induces Rapid Macrophage Death
by Atsushi Koikea and Makio Shibanob and Hideya Moria and Kiyoko Kohamaa and Ko Fujimoria and Fumio Amanoa and Osaka University of Pharmaceutical Sciences and bLaboratory of Pharmacognosy and aLaboratory of Biodefense & Regulation
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2016, Volume 39, Issue 6, pp. 969 - 976
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10. Full Text Corrigendum: Shikonin Inhibits Cancer Through P21 Upregulation and Apoptosis Induction
by Wang, Fangfang and Mayca Pozo, Franklin and Tian, Danmei and Geng, Xinran and Yao, Xinsheng and Zhang, Youwei and Tang, Jinshan
Frontiers in pharmacology, ISSN 1663-9812, 07/2020, Volume 11, pp. 1088 - 1088
apoptosis | autophagy | cell cycle arrest | Shikonin | P21 | anticancer effect
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11. Full Text Design, synthesis and biological evaluation of benzoylacrylic acid shikonin ester derivatives as irreversible dual inhibitors of tubulin and EGFR
by Sun, Wen-Xue and Han, Hong-Wei and Yang, Min-Kai and Wen, Zhong-Ling and Wang, Yin-Song and Fu, Jiang-Yan and Lu, Yun-Ting and Wang, Ming-Yue and Bao, Jia-Xin and Lu, Gui-Hua and Qi, Jin-Liang and Wang, Xiao-Ming and Lin, Hong-Yan and Yang, Yong-Hua
Bioorganic & medicinal chemistry, ISSN 0968-0896, 12/2019, Volume 27, Issue 23, pp. 115153 - 115153
Tubulin | Anticancer | Shikonin | Benzoylacrylic | Epidermal growth factor receptor | Afatinib (PubChem CID: 10184653) | Bromobenzene (PubChem CID: 7961) | Chlorobenzene (PubChem CID: 7964) | Benzene (PubChem CID: 241) | Shikonin (PubChem CID: 479503) | Methylbenzene (PubChem CID: 1140) | Fluorobenzene (PubChem CID: 10008) | Maleic anhydride (PubChem CID: 7923) | Colchicine (PubChem CID: 6167) | Paclitaxel (PubChem CID: 36314) | Index Medicus
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12. Full Text Comparative genome/transcriptome analysis probes Boraginales' phylogenetic position, WGDs in Boraginales, and key enzyme genes in the alkannin/shikonin core pathway
by Tang, Cheng‐Yi and Li, Song and Wang, Yun‐Tong and Wang, Xi
Molecular ecology resources, ISSN 1755-098X, 01/2020, Volume 20, Issue 1, pp. 228 - 241
whole genome duplications | Boraginales' phylogenetic position | alkannin/shikonin pathway | Echium plantagineum genome | Biochemistry & Molecular Biology | Environmental Sciences & Ecology | Ecology | Life Sciences & Biomedicine | Evolutionary Biology | Science & Technology | Enzymes | DNA probes | Shikonin | Hydroxylase | Genes | Phylogenetics | Genomes | Naphthol | Phylogeny | Gene expression | Index Medicus
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13. Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats
by Yang, Weijia and Yang, Minchun and Yao, Hui and Ma, Yelin and Ren, Xuanxuan and Teng, Long and Wang, Tao
Pakistan journal of pharmaceutical sciences, ISSN 1011-601X, 11/2020, Volume 33, Issue 6, pp. 2527 - 2533
Shikonin | Fibrosis | Lipid accumulation | Nonalcoholic fatty liver disease | Liver injury
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14. Full Text Identification of onosma visianii roots extract and purified shikonin derivatives as potential acaricidal agents against tetranychus urticae
by Sut, Stefania and Pavela, Roman and Kolarcik, Vladislav and Cappellacci, Loredana and Petrelli, Riccardo and Maggi, Filippo and Dall’Acqua, Stefano and Benelli, Giovanni
Molecules (Basel, Switzerland), ISSN 1420-3049, 06/2017, Volume 22, Issue 6, p. 1002
Eco-friendly insecticide | Onosma visianii | Tetranychus urticae | Shikonin derivatives | Biopesticide | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Plant Extracts - chemistry | Acaricides - chemistry | Animals | Plant Extracts - pharmacology | Plant Roots - chemistry | Naphthoquinones - chemistry | Tetranychidae - drug effects | Acaricides - pharmacology | Boraginaceae - chemistry | Lipophilic | Toxicity | Shikonin | Roots | Pesticides | Oviposition | Plants | Derivatives | Index Medicus
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15. Full Text Antibiofilm activity of shikonin against Listeria monocytogenes and inhibition of key virulence factors
by Li, Jiahui and Li, Siqi and Li, Haozhou and Guo, Xinyu and Guo, Du and Yang, Yanpeng and Wang, Xin and Zhang, Chunling and Shan, Zhongguo and Xia, Xiaodong and Shi, Chao
Food control, ISSN 0956-7135, 02/2021, Volume 120, p. 107558
Listeria monocytogenes | Antibiofilm | Listeriolysin | Shikonin | HT-29 | Anti-infectious | Life Sciences & Biomedicine | Food Science & Technology | Science & Technology
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16. Full Text Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome
by Guo, Tao and Jiang, Zhong-Biao and Tong, Zhong-Yi and Zhou, Yang and Chai, Xiang-Ping and Xiao, Xian-Zhong
Frontiers in physiology, ISSN 1664-042X, 10/2020, Volume 11, pp. 570441 - 570441
Life Sciences & Biomedicine | Physiology | Science & Technology | Heart | Mitogens | NLRP3 | cardiac dysfunction | lipopolysaccharide | SIRT1 | shikonin
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