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1. Full Text A systematic review of the use of resuscitative endovascular balloon occlusion of the aorta in the management of hemorrhagic shock
by Morrison, Jonathan James and Galgon, Richard E and Jansen, Jan Olaf and Cannon, Jeremy W and Rasmussen, Todd Erik and Eliason, Jonathan L
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 02/2016, Volume 80, Issue 2, pp. 324 - 334
BACKGROUND: Torso hemorrhage remains a leading cause of potentially preventable death within trauma, acute care, vascular, and obstetric practice. A proportion... 
resuscitation | REBOA | trauma surgery | hemorrhage control | Resuscitative endovascular balloon occlusion of the aorta | SURGERY | CESAREAN HYSTERECTOMY | BLOOD-LOSS | MODEL | REPAIR | ABDOMINAL-AORTA | CATHETER | TRAUMA PATIENTS | EPIDEMIOLOGY | NONCOMPRESSIBLE TORSO HEMORRHAGE | FEMORAL-ARTERY | CRITICAL CARE MEDICINE | Shock, Hemorrhagic - etiology | Balloon Occlusion | Humans | Shock, Hemorrhagic - mortality | Aorta | Shock, Hemorrhagic - therapy | Resuscitation
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2. Full Text The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock
by Minei, Joseph P and Cuschieri, Joseph and Sperry, Jason and Moore, Ernest E and West, Michael A and Harbrecht, Brian G and O’Keefe, Grant E and Cohen, Mitchell J and Moldawer, Lyle L and Tompkins, Ronald G and Maier, Ronald V and Inflammation Host Response Injury and Inflammation and the Host Response to Injury Collaborative Research Program
Critical Care Medicine, ISSN 0090-3493, 04/2012, Volume 40, Issue 4, pp. 1129 - 1135
OBJECTIVES:To describe the incidence of postinjury multiple organ failure and its relationship to nosocomial infection and mortality in trauma centers using... 
trauma | mortality | multiple organ failure | infection | injury | standards of care | SCALE COLLABORATIVE PROJECT | TIDAL VOLUME | STANDARD OPERATING PROCEDURES | CLINICAL CARE | ACUTE LUNG INJURY | ORIENTED RESEARCH CORE | HOST RESPONSE | TRAUMA PATIENT | INFLAMMATION | SYSTEM FAILURE | CRITICAL CARE MEDICINE | Shock, Hemorrhagic - complications | Wounds, Nonpenetrating - complications | Prospective Studies | Shock, Hemorrhagic - etiology | Cross Infection - etiology | Hospital Mortality | Humans | Middle Aged | Proportional Hazards Models | Male | Incidence | Injury Severity Score | Multiple Organ Failure - epidemiology | Multiple Organ Failure - etiology | Adult | Female | Trauma Centers - statistics & numerical data | Trauma Centers - standards | Cross Infection - epidemiology
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3. Full Text Image Gallery: Haemorrhagic shock due to a cutaneous pyogenic granuloma
by Kramer, O.N and Jerdan, K and Worobec, S.M
British Journal of Dermatology, ISSN 0007-0963, 08/2017, Volume 177, Issue 2, pp. e24 - e24
DERMATOLOGY | Male | Skin Diseases - complications | Shock, Hemorrhagic - etiology | Granuloma, Pyogenic - complications | Humans | Middle Aged | Granuloma
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4. Full Text Transfusion of Plasma, Platelets, and Red Blood Cells in a 1:1:1 vs a 1:1:2 Ratio and Mortality in Patients With Severe Trauma: The PROPPR Randomized Clinical Trial
by Holcomb, John B and Tilley, Barbara C and Baraniuk, Sarah and Fox, Erin E and Wade, Charles E and Podbielski, Jeanette M and del Junco, Deborah J and Brasel, Karen J and Bulger, Eileen M and Callcut, Rachael A and Cohen, Mitchell Jay and Cotton, Bryan A and Fabian, Timothy C and Inaba, Kenji and Kerby, Jeffrey D and Muskat, Peter and O’Keeffe, Terence and Rizoli, Sandro and Robinson, Bryce R. H and Scalea, Thomas M and Schreiber, Martin A and Stein, Deborah M and Weinberg, Jordan A and Callum, Jeannie L and Hess, John R and Matijevic, Nena and Miller, Christopher N and Pittet, Jean-Francois and Hoyt, David B and Pearson, Gail D and Leroux, Brian and van Belle, Gerald and PROPPR Study Grp and PROPPR Study Group
JAMA, ISSN 0098-7484, 02/2015, Volume 313, Issue 5, pp. 471 - 482
IMPORTANCE: Severely injured patients experiencing hemorrhagic shock often require massive transfusion. Earlier transfusion with higher blood product ratios... 
SURVIVAL | MEDICINE, GENERAL & INTERNAL | MULTICENTER | DAMAGE CONTROL RESUSCITATION | PRODUCTS | MAJOR TRAUMA | RISK | MASSIVE TRANSFUSION | COAGULOPATHY | MULTIPLE-ORGAN FAILURE | FRESH-FROZEN PLASMA | Blood Component Transfusion - methods | Plasma | Shock, Hemorrhagic - etiology | Humans | Blood Platelets | Erythrocytes | Wounds and Injuries - complications | Exsanguination - mortality | Male | Shock, Hemorrhagic - therapy | Exsanguination - therapy | Wounds and Injuries - mortality | Wounds and Injuries - therapy | Exsanguination - etiology | Hemostasis | Female | Psychological aspects | Usage | Mortality | Analysis | Clinical trials | Research | Psychic trauma | Hemorrhage | Patients | Health aspects | Risk factors | Blood transfusions | Trauma | Clinical outcomes
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5. Hemorrhagic shock and treatment of severe bleeding
by Seidlová, Dagmar and Buliková, Alena
Vnitrni lekarstvi, ISSN 0042-773X, 2019, Volume 65, Issue 3, p. 211
Hemorrhagic shock is a severe complication of conditions that are accompanied by massive bleeding and is associated with high mortality and morbidity. The... 
Shock, Hemorrhagic - etiology | Humans | Hemorrhage - complications | Shock, Hemorrhagic - therapy
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6. Full Text Resuscitative Endovascular Balloon Occlusion of the Aorta and Resuscitative Thoracotomy in Select Patients with Hemorrhagic Shock: Early Results from the American Association for the Surgery of Trauma's Aortic Occlusion in Resuscitation for Trauma and Acute Care Surgery Registry
by Brenner, Megan and Inaba, Kenji and Aiolfi, Alberto and DuBose, Joseph and Fabian, Timothy and Bee, Tiffany and Holcomb, John B and Moore, Laura and Skarupa, David and Scalea, Thomas M and Rasmussen, Todd E and Wasicek, Philip and Podbielski, Jeanette M and Trexler, Scott T and Charo-Griego, Sonya and Johnson, Douglas and Cannon, Jeremy and Matthew, Sarah and Turay, David and Arbabi, Cassra N and Luo-Owen, Xian and Skarupa, David and Mull, Jennifer A and Gonzalez, Joannis Baez and Ibrahim, Joseph and Safcsak, Karen and Gordy, Stephanie and Long, Michael and Kirkpatrick, Andrew W and Ball, Chad and Xiao, Zhengwen and Dauer, Elizabeth and Knight, Jennifer and Cornell, Nicole and Skaja, Joseph and Nygaard, Rachel and Richardson, Chad and Bloom, Matthew and Tran, Nam T and Aarabi, Shahram and Bulger, Eileen and Ward, Jeannette G and Bini, John K and Matsuura, John and Pringle, Joshua and Herzing, Karen and Nolan, Kailey and Poulin, Nathaniel and Teeter, William and AAST AORTA Study Grp and AAST AORTA Study Group
Journal of the American College of Surgeons, ISSN 1072-7515, 05/2018, Volume 226, Issue 5, pp. 730 - 740
Background: Aortic occlusion is a potentially valuable tool for early resuscitation in patients nearing extremis or in arrest from severe hemorrhage. Study... 
SURGERY | CARDIAC-ARREST | Prospective Studies | Resuscitation - methods | Shock, Hemorrhagic - etiology | United States | Humans | Middle Aged | Male | Survival Rate | Treatment Outcome | Shock, Hemorrhagic - therapy | Aorta, Thoracic | Balloon Occlusion - methods | Injury Severity Score | Shock, Hemorrhagic - mortality | Thoracotomy - methods | Adult | Female | Thoracic Injuries - complications
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7. Full Text Hemorrhagic shock
by Gann, Donald S and Drucker, William R
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 11/2013, Volume 75, Issue 5, pp. 888 - 895
SURGERY | HEMOGLOBIN SOLUTION | OXYGEN-CONSUMPTION | DAMAGE CONTROL RESUSCITATION | MASSIVE TRANSFUSION | DEPOLARIZES CELLS | BLOOD-VOLUME | FRESH-FROZEN PLASMA | BACTERIAL TRANSLOCATION | HYPERTONIC SALINE 7.5-PERCENT | FLUID RESUSCITATION | CRITICAL CARE MEDICINE | Animals | Resuscitation - methods | Shock, Hemorrhagic - etiology | Wounds and Injuries - therapy | Humans | Wounds and Injuries - complications | Wounds and Injuries - diagnosis | Shock, Hemorrhagic - therapy | Shock, Hemorrhagic - diagnosis | Trauma Severity Indices
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8. Full Text Traumatic brain injury and hemorrhagic shock: Evaluation of different resuscitation strategies in a large animal model of combined insults
by Jin, Guang and Demoya, Marc A and Duggan, Michael and Knightly, Thomas and Mejaddam, Ali Y and Hwabejire, John and Lu, Jennifer and Smith, William Michael and Kasotakis, Georgios and Velmahos, George C and Socrate, Simona and Alam, Hasan B
Shock, ISSN 1073-2322, 07/2012, Volume 38, Issue 1, pp. 49 - 56
Traumatic brain injury (TBI) and hemorrhagic shock (HS) are the leading causes of trauma-related mortality and morbidity. Combination of TBI and HS (TBI + HS)... 
swine | Traumatic brain injury | edema | shock | hemorrhage | SURGERY | HEAD-INJURY | FOCAL CEREBRAL-ISCHEMIA | TISSUE | HEMODILUTION | FLUID RESUSCITATION | IMPACT | COAGULATION | PERIPHERAL VASCULAR DISEASE | POLYTRAUMA | HEMATOLOGY | FRESH-FROZEN PLASMA | CRITICAL CARE MEDICINE | Plasma | Resuscitation - methods | Shock, Hemorrhagic - etiology | Brain Edema - etiology | Brain Edema - pathology | Brain Injuries - complications | Brain Edema - therapy | Shock, Hemorrhagic - therapy | Brain Injuries - therapy | Brain Injuries - physiopathology | Hemodynamics - physiology | Carbon Dioxide - blood | Intracranial Pressure - physiology | Sodium Chloride - therapeutic use | Oxygen - blood | Animals | Partial Pressure | Shock, Hemorrhagic - physiopathology | Hydroxyethyl Starch Derivatives - therapeutic use | Female | Brain Injuries - pathology | Sus scrofa | Disease Models, Animal
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9. Full Text Haemorrhage control in severely injured patients
by Gruen, Russell L, Prof and Brohi, Karim, Prof and Schreiber, Martin, Prof and Balogh, Zsolt J, Prof and Pitt, Veronica, PhD and Narayan, Mayur, MD and Maier, Ronald V, Prof
Lancet, The, ISSN 0140-6736, 2012, Volume 380, Issue 9847, pp. 1099 - 1108
Summary Most surgeons have adopted damage control surgery for severely injured patients, in which the initial operation is abbreviated after control of... 
Internal Medicine | MEDICINE, GENERAL & INTERNAL | ACUTE TRAUMATIC COAGULOPATHY | LYOPHILIZED PLASMA | HYPERTONIC RESUSCITATION | COAGULATION | MASSIVE TRANSFUSION | DAMAGE CONTROL | PROTEIN-C | FIBRINOGEN | FACTOR-VIIA | BLOOD | Wounds and Injuries - surgery | Shock, Hemorrhagic - etiology | Blood Coagulation Disorders - etiology | Humans | Wounds and Injuries - complications | Hemorrhage - prevention & control | Shock, Hemorrhagic - therapy | Blood Coagulation Disorders - therapy | Systemic Inflammatory Response Syndrome - therapy | Microcirculation - physiology | Hemostatic Techniques | Hemorrhage - etiology | Shock, Hemorrhagic - physiopathology | Systemic Inflammatory Response Syndrome - etiology | Hemostatics - therapeutic use | Prevention | Complications and side effects | Care and treatment | Hemorrhage | Wounds and injuries | Risk factors
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10. Full Text Intraluminal Nonbacterial Intestinal Components Control Gut and Lung Injury After Trauma Hemorrhagic Shock
by Fishman, Jordan E and Sheth, Sharvil U and Levy, Gal and Alli, Vamsi and Lu, Qu and Xu, Dazhong and Qin, Yung and Qin, Xiaofa and Deitch, Edwin A
Annals of Surgery, ISSN 0003-4932, 12/2014, Volume 260, Issue 6, pp. 1112 - 1120
OBJECTIVE:To test whether the mucus layer, luminal digestive enzymes, and intestinal mast cells are critical components in the pathogenesis of trauma... 
Shock | Intestinal mast cells | Hemorrhagic shock | Intestinal mucus | Ischemic-reperfusion injury | Trauma | trauma | PANCREATIC-ENZYMES | SURGERY | PERMEABILITY | intestinal mucus | shock | MAST-CELLS | hemorrhagic shock | intestinal mast cells | MUCUS LAYER | BACTERIAL TRANSLOCATION | INFLAMMATION | ACTIVATING FACTORS | NITRIC-OXIDE | END | BARRIER FAILURE | ischemic-reperfusion injury | Shock, Hemorrhagic - etiology | Acute Lung Injury - therapy | Wounds and Injuries - complications | Rats | Male | Pancreatic Elastase - metabolism | Shock, Hemorrhagic - therapy | Rats, Sprague-Dawley | Animals | Intestinal Mucosa - enzymology | Acute Lung Injury - etiology | Enzymes - metabolism | Disease Models, Animal | Intestines - enzymology
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11. Full Text The trauma center is too late: Major limb trauma without a pre-hospital tourniquet has increased death from hemorrhagic shock
by Scerbo, Michelle H and Holcomb, John B and Taub, Ethan and Gates, Keith and Love, Joseph D and Wade, Charles E and Cotton, Bryan A
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 12/2017, Volume 83, Issue 6, pp. 1165 - 1172
BACKGROUND To date, no civilian studies have demonstrated that pre-hospital (PH) tourniquets improve survival. We hypothesized that late, trauma center (TC)... 
Tourniquet | hemorrhagic shock | major limb trauma | pre-hospital | MORTALITY | SURGERY | BATTLEFIELD | EMERGENCY TOURNIQUETS | WAR | LESSONS | OPERATION-IRAQI-FREEDOM | CRITICAL CARE MEDICINE | Hemostatic Techniques - instrumentation | Shock, Hemorrhagic - etiology | Survival Rate - trends | Follow-Up Studies | Hemorrhage - therapy | Humans | Middle Aged | Hemorrhage - complications | Hemorrhage - mortality | Trauma Centers | Male | Shock, Hemorrhagic - therapy | Urban Population | Tourniquets - statistics & numerical data | Arm Injuries - complications | Shock, Hemorrhagic - mortality | Adult | Female | Time-to-Treatment - trends | Emergency Medical Services - methods | Retrospective Studies | Leg Injuries - complications | Texas - epidemiology
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12. Full Text Traumatic brain injury causes platelet adenosine diphosphate and arachidonic acid receptor inhibition independent of hemorrhagic shock in humans and rats
by Castellino, Francis J and Chapman, Michael P and Donahue, Deborah L and Thomas, Scott and Moore, Ernest E and Wohlauer, Max V and Fritz, Braxton and Yount, Robert and Ploplis, Victoria and Davis, Patrick and Evans, Edward and Walsh, Mark
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 2014, Volume 76, Issue 5, pp. 1169 - 1176
BACKGROUND: Coagulopathy in traumatic brain injury (CTBI) is a well established phenomenon, but its mechanism is poorly understood. Various studies implicate... 
platelet | Traumatic brain injury | coagulopathy | ADP receptor | thrombelastography | SURGERY | ACTIVATION | TISSUE | HYPOPERFUSION | PROTEIN-C PATHWAY | EARLY COAGULOPATHY | DYSFUNCTION | REPLACE | CRITICAL CARE MEDICINE | Prospective Studies | Shock, Hemorrhagic - etiology | Humans | Middle Aged | Arachidonic Acid - blood | Platelet Activation - physiology | Brain Injuries - complications | Male | Purinergic P2Y Receptor Antagonists - blood | Reference Values | Blood Platelets - physiology | Case-Control Studies | Arachidonic Acid - antagonists & inhibitors | Glasgow Coma Scale | Platelet Function Tests | Statistics, Nonparametric | Adult | Brain Injuries - blood | Female | Disease Models, Animal | Thrombelastography | Risk Assessment | Blood Coagulation Disorders - etiology | Rats | Rats, Sprague-Dawley | Shock, Hemorrhagic - blood | Animals | Blood Coagulation Disorders - blood | Blood Coagulation Tests
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13. Full Text The immunomodulatory effects of hypertonic saline resuscitation in patients sustaining traumatic hemorrhagic shock: A randomized, controlled, double-blinded trial
by Rizoli, Sandro B and Rhind, Shawn G and Shek, Pang N and Inaba, Kenji and Filips, Dennis and Tein, Homer and Brenneman, Fred and Rotstein, Ori
Annals of Surgery, ISSN 0003-4932, 01/2006, Volume 243, Issue 1, pp. 47 - 57
Objective: To investigate the potential immunologic and anti-inflammatory effects of hypertonic saline plus dextran (HSD) in hemorrhagic trauma patients.... 
MACROPHAGE FUNCTION | SURGERY | L-SELECTIN | NEUTROPHIL ACTIVATION | INJURY | 6-PERCENT DEXTRAN-70 | INFUSION | BLOOD MONOCYTES | IMMUNE FUNCTION | CYTOKINE EXPRESSION | NEUROENDOCRINE RESPONSES | Wounds, Nonpenetrating - complications | Prospective Studies | Shock, Hemorrhagic - etiology | Double-Blind Method | Hormones - biosynthesis | Humans | Middle Aged | Antigens, Surface - biosynthesis | Male | Inflammation - immunology | Shock, Hemorrhagic - therapy | Leukocytes - immunology | Inflammation - therapy | Wounds, Nonpenetrating - immunology | Adult | Female | Saline Solution, Hypertonic - therapeutic use | Aged | Shock, Hemorrhagic - immunology | Dextrans - therapeutic use | Cytokines - biosynthesis | Immunologic Factors - therapeutic use | Randomized Controlled Trial
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14. Full Text Human Polymerized Hemoglobin for the Treatment of Hemorrhagic Shock when Blood Is Unavailable: The USA Multicenter Trial
by Moore, Ernest E., MD, FACS and Moore, Frederick A., MD, FACS and Fabian, Timothy C., MD, FACS and Bernard, Andrew C., MD, FACS and Fulda, Gerard J., MD, FACS and Hoyt, David B., MD, FACS and Duane, Therese M., MD, FACS and Weireter, Leonard J., MD, FACS and Gomez, Gerardo A., MD, FACS and Cipolle, Mark D., MD, FACS and Rodman, George H., MD, FACS and Malangoni, Mark A., MD, FACS and Hides, George A., BA and Omert, Laurel A., MD and Gould, Steven A., MD, FACS and PolyHeme Study Grp and PolyHeme Study Group
Journal of the American College of Surgeons, ISSN 1072-7515, 2008, Volume 208, Issue 1, pp. 1 - 13
Background Human polymerized hemoglobin (PolyHeme, Northfield Laboratories) is a universally compatible oxygen carrier developed to treat life-threatening... 
Surgery | SURGERY | CELL-FREE HEMOGLOBIN | PULMONARY-HYPERTENSION | OXYGEN CARRIERS | JEHOVAH-WITNESS | CLINICAL-TRIALS | STROMA-FREE HEMOGLOBIN | RANDOMIZED-TRIAL | INJURED PATIENT | CROSS-LINKED HEMOGLOBIN | PYRIDOXYLATED HEMOGLOBIN | Fluid Therapy | Shock, Hemorrhagic - etiology | Erythrocyte Transfusion | United States | Humans | Middle Aged | Isotonic Solutions - administration & dosage | Wounds and Injuries - complications | Trauma Centers | Hypotension - therapy | Male | Shock, Hemorrhagic - therapy | Urban Population | Hemoglobins - administration & dosage | Blood Substitutes - administration & dosage | Survival Analysis | Adult | Female | Hypotension - etiology | Aged | Emergency Medical Services | Rehydration Solutions - administration & dosage
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