Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3915) 3915
Publication (439) 439
Book / eBook (85) 85
Book Review (49) 49
Newsletter (25) 25
Book Chapter (24) 24
Government Document (7) 7
Magazine Article (7) 7
Conference Proceeding (2) 2
Data Set (1) 1
Dissertation (1) 1
Newspaper Article (1) 1
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (2544) 2544
male (1989) 1989
humans (1552) 1552
index medicus (1523) 1523
rats (1238) 1238
female (990) 990
hemorrhagic-shock (831) 831
surgery (796) 796
shock, hemorrhagic - pathology (785) 785
disease models, animal (705) 705
rats, sprague-dawley (617) 617
shock (579) 579
critical care medicine (556) 556
resuscitation (545) 545
hemorrhagic shock (504) 504
inflammation (496) 496
mice (489) 489
adult (446) 446
sepsis (434) 434
shock, hemorrhagic - physiopathology (407) 407
research (404) 404
shock, hemorrhagic - complications (391) 391
middle aged (380) 380
lung - pathology (376) 376
hemorrhage (374) 374
septic shock (364) 364
trauma (356) 356
hematology (349) 349
peripheral vascular disease (345) 345
liver - pathology (340) 340
injury (339) 339
dogs (329) 329
time factors (326) 326
pathology (304) 304
shock, hemorrhagic - therapy (294) 294
rats, wistar (293) 293
research article (293) 293
immunology (286) 286
medicine (285) 285
health aspects (282) 282
mortality (282) 282
rodents (278) 278
shock, hemorrhagic - metabolism (278) 278
blood pressure (272) 272
ischemia (270) 270
apoptosis (268) 268
aged (266) 266
physiology (264) 264
shock, hemorrhagic - etiology (261) 261
cell biology (231) 231
care and treatment (220) 220
shock, hemorrhagic - drug therapy (220) 220
cytokines (208) 208
abridged index medicus (204) 204
liver (202) 202
swine (201) 201
oxidative stress (196) 196
expression (195) 195
activation (192) 192
risk factors (190) 190
article (183) 183
analysis (182) 182
proteins (182) 182
mice, inbred c57bl (181) 181
multidisciplinary sciences (181) 181
hemodynamics (178) 178
multiple organ failure (178) 178
physiological aspects (171) 171
random allocation (168) 168
tumor-necrosis-factor (166) 166
medicine, research & experimental (164) 164
permeability (163) 163
resuscitation - methods (163) 163
science (163) 163
lung injury (157) 157
intestinal mucosa - pathology (155) 155
reperfusion (151) 151
necrosis (148) 148
gastroenterology & hepatology (147) 147
adolescent (145) 145
model (144) 144
treatment outcome (144) 144
pharmacology & pharmacy (143) 143
ischemia-reperfusion injury (142) 142
kidney - pathology (142) 142
diagnosis (141) 141
blood (140) 140
rabbits (140) 140
acute lung injury (136) 136
liver - metabolism (136) 136
injuries (133) 133
infectious diseases (132) 132
nitric-oxide (132) 132
lung - metabolism (130) 130
cells (129) 129
reperfusion injury - pathology (129) 129
shock, hemorrhagic - blood (129) 129
neutrophils (128) 128
inflammatory response (126) 126
rat (126) 126
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (72) 72
Collection Dvlpm't (Acquisitions) - Closed Orders (4) 4
Online Resources - Online (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Providence Healthcare - Stacks (1) 1
Robarts - Stacks (1) 1
Scarborough Hospital - General (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
UTL at Downsview - May be requested (1) 1
UofT at Mississauga - Stacks (1) 1
UofT at Scarborough - Stacks (1) 1
Victoria University E.J. Pratt - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3705) 3705
German (92) 92
Chinese (68) 68
French (49) 49
Russian (45) 45
Japanese (31) 31
Italian (18) 18
Spanish (16) 16
Polish (11) 11
Romanian (8) 8
Hungarian (6) 6
Bulgarian (3) 3
Portuguese (3) 3
Slovak (3) 3
Danish (2) 2
Norwegian (2) 2
Turkish (2) 2
Dutch (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text Hemorrhagic shock activation of NLRP3 inflammasome in lung endothelial cells
by Xiang, Meng and Shi, Xiaolian and Li, Yuehua and Xu, Jia and Yin, Lianhua and Xiao, Guozhi and Scott, Melanie J and Billiar, Timothy R and Wilson, Mark A and Fan, Jie
Journal of Immunology, ISSN 0022-1767, 11/2011, Volume 187, Issue 9, pp. 4809 - 4817
Hemorrhagic shock (HS) due to major trauma and surgery predisposes the host to the development of systemic inflammatory response syndrome (SIRS), including... 
NEUTROPHIL NADPH OXIDASE | NAD(P)H OXIDASE | ISCHEMIA/REPERFUSION INJURY | SEVERE BLUNT TRAUMA | INTERLEUKIN-1 RECEPTOR ANTAGONIST | MOBILITY GROUP BOX-1 | ALVEOLAR MACROPHAGES | MULTIPLE ORGAN FAILURE | IMMUNOLOGY | TLR2 UP-REGULATION | RESPIRATORY-DISTRESS-SYNDROME | Inflammasomes - metabolism | Shock, Hemorrhagic - metabolism | Carrier Proteins - secretion | NLR Family, Pyrin Domain-Containing 3 Protein | Male | Respiratory Mucosa - pathology | Respiratory Mucosa - immunology | HMGB1 Protein - physiology | Respiratory Mucosa - secretion | Disease Models, Animal | Endothelium, Vascular - immunology | Interleukin-1beta - secretion | Shock, Hemorrhagic - pathology | Lung - pathology | Mice, Inbred C57BL | Cells, Cultured | Mice, Transgenic | Mice, Knockout | Animals | Endothelium, Vascular - secretion | Inflammasomes - immunology | Endothelium, Vascular - pathology | Mice | Shock, Hemorrhagic - immunology | Lung - secretion | Inflammasomes - secretion | Lung - immunology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Frontline Science: Macrophage‐derived exosomes promote neutrophil necroptosis following hemorrhagic shock
by Jiao, Yang and Li, Zhigang and Loughran, Patricia A and Fan, Erica K and Scott, Melanie J and Li, Yuehua and Billiar, Timothy R and Wilson, Mark A and Shi, Xueyin and Fan, Jie
Journal of Leukocyte Biology, ISSN 0741-5400, 02/2018, Volume 103, Issue 2, pp. 175 - 183
Hemorrhagic shock (HS) renders patients susceptible to development of systemic inflammatory response syndrome (SIRS) and multiple organ dysfunction syndrome... 
cell death | cell‐cell interaction | extracellular vesicles | cell-cell interaction | NADPH OXIDASE | LUNG | ACTIVATION | MECHANISMS | NLRP3 INFLAMMASOME | AUTOPHAGY | IMMUNOLOGY | CELL BIOLOGY | NECROSIS | ALVEOLAR MACROPHAGES | INFLAMMATORY RESPONSE | HEMATOLOGY | EXPRESSION | Inflammation - pathology | Shock, Hemorrhagic - pathology | Macrophages, Alveolar - pathology | Reactive Oxygen Species - metabolism | Coculture Techniques | Humans | Mice, Inbred C57BL | NADPH Oxidases - metabolism | Exosomes - pathology | Male | Necrosis | Animals | Mice | Primary Cell Culture | Disease Models, Animal | Neutrophils - pathology
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Hemorrhagic Shock Induces NAD(P)H Oxidase Activation in Neutrophils: Role of HMGB1-TLR4 Signaling
by Fan, Jie and Li, Yuehua and Levy, Ryan M and Fan, Janet J and Hackam, David J and Vodovotz, Yoram and Yang, Huan and Tracey, Kevin J and Billiar, Timothy R and Wilson, Mark A
The Journal of Immunology, ISSN 0022-1767, 05/2007, Volume 178, Issue 10, pp. 6573 - 6580
Hemorrhagic shock/resuscitation (HS/R)-induced generation of reactive oxygen species (ROS) plays an important role in posthemorrhage inflammation and tissue... 
SYSTEMIC INFLAMMATION | NADPH OXIDASE | PROTEIN-KINASE-C | TOLL-LIKE RECEPTOR-4 | MOBILITY GROUP BOX-1 | IMMUNOLOGY | MEDIATES HEPATIC-INJURY | END-PRODUCTS RAGE | NF-KAPPA-B | LUNG INFLAMMATION | CUTTING EDGE | Shock, Hemorrhagic - pathology | Neutrophil Activation - immunology | Reperfusion Injury - pathology | Reperfusion Injury - enzymology | NADPH Oxidases - metabolism | Male | Enzyme Activation - immunology | Mice, Inbred C3H | Toll-Like Receptor 4 - physiology | Signal Transduction - immunology | Animals | Shock, Hemorrhagic - enzymology | Reperfusion Injury - immunology | Mice | NADPH Oxidases - biosynthesis | Shock, Hemorrhagic - immunology | HMGB1 Protein - physiology | Resuscitation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Physiologic tolerance of descending thoracic aortic balloon occlusion in a swine model of hemorrhagic shock
by Markov, Nickolay P., MD and Percival, Thomas J., MD and Morrison, Jonathan J., MRCS and Ross, James D., PhD and Scott, Daniel J., MD and Spencer, Jerry R., BS and Rasmussen, Todd E., MD
Surgery: Official Journal of the Society of University Surgeons, Central Surgical Association, and the American Association of Endocrine Surgeons, ISSN 0039-6060, 2013, Volume 153, Issue 6, pp. 848 - 856
Background Resuscitative endovascular balloon occlusion of the aorta (REBOA) is an emerging technique in trauma; however, the physiologic sequelae have not... 
Surgery | SURGERY | PORCINE MODEL | EMERGENCY-DEPARTMENT THORACOTOMY | MANAGEMENT | TRAUMA | Blood Pressure | Fluid Therapy | Shock, Hemorrhagic - pathology | Resuscitation - methods | Lactic Acid - blood | Shock, Hemorrhagic - therapy | Aorta, Thoracic - physiopathology | Balloon Occlusion - methods | Animals | Blood Transfusion | Endovascular Procedures - methods | Shock, Hemorrhagic - physiopathology | Female | Hemodynamics | Reperfusion - methods | Sus scrofa | Disease Models, Animal | Shock | Swine | Analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Cerebral Alterations Following Experimental Multiple Trauma and Hemorrhagic Shock
by Vogt, Nina and Herden, Christiane and Roeb, Elke and Roderfeld, Martin and Eschbach, Daphne and Steinfeldt, Thorsten and Wulf, Hinnerk and Ruchholtz, Steffen and Uhl, Eberhard and Schöller, Karsten
SHOCK, ISSN 1073-2322, 02/2018, Volume 49, Issue 2, pp. 164 - 173
ABSTRACTMultiple trauma (MT) associated with hemorrhagic shock (HS) might lead to cerebral hypoperfusion and brain damage. We investigated cerebral alterations... 
cerebral monitoring | porcine trauma model | Biomarker | hypothermia | microglia | SURVIVAL | SURGERY | BRAIN-INJURY | SWINE | VALPROIC ACID | MODEL | RECOVERY | NEURON-SPECIFIC-ENOLASE | PLASMA | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | RESUSCITATION | CRITICAL CARE MEDICINE | Immunohistochemistry | Microglia - metabolism | Shock, Hemorrhagic - pathology | Cerebrovascular Circulation - physiology | Enzyme-Linked Immunosorbent Assay | Multiple Trauma - pathology | Astrocytes - pathology | Male | Intracranial Pressure - physiology | Animals | Swine | Hypothermia, Induced | Microglia - pathology | Cerebrum - metabolism | Brain Injuries - pathology | Cerebrum - pathology | Astrocytes - metabolism | Disease Models, Animal | Nitric Oxide Synthase Type II - metabolism | Complications and side effects | Brain | Hemorrhagic shock | Medical examination | Brain research | Cerebrum | Injuries
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Full Text PAD4 deficiency leads to decreased organ dysfunction and improved survival in a dual insult model of hemorrhagic shock and sepsis
by Biron, Bethany M and Chung, Chun-Shiang and Chen, Yaping and Wilson, Zachary and Fallon, Eleanor A and Reichner, Jonathan S and Ayala, Alfred
Journal of Immunology, ISSN 0022-1767, 03/2018, Volume 200, Issue 5, pp. 1817 - 1828
Indirect acute respiratory distress syndrome (iARDS) is caused by a nonpulmonary inflammatory process resulting from insults such as nonpulmonary sepsis.... 
NEUTROPHIL EXTRACELLULAR TRAPS | POLYMICROBIAL SEPSIS | HISTONE DEIMINATION | PEPTIDYLARGININE DEIMINASE | SEPTIC SHOCK | CL-AMIDINE | ACUTE LUNG INJURY | MICE | IMMUNOLOGY | T-CELLS | RESPIRATORY-DISTRESS-SYNDROME | Hydrolases - metabolism | Multiple Organ Failure - metabolism | Respiratory Distress Syndrome, Adult - pathology | Chromatin - metabolism | Shock, Hemorrhagic - pathology | Lung - pathology | Shock, Hemorrhagic - metabolism | Extracellular Traps - metabolism | Mice, Inbred C57BL | Male | Neutrophil Activation - physiology | Respiratory Distress Syndrome, Adult - metabolism | Animals | Sepsis - pathology | Sepsis - metabolism | Lung - metabolism | Mice | Histones - metabolism | Neutrophils - metabolism | Disease Models, Animal | Multiple Organ Failure - pathology | Chromatin | Cecum | Neutrophils | Leukocytes (neutrophilic) | Inflammation | Citrulline | Hemorrhage | Survival | Microorganisms | Clonal deletion | Respiratory distress syndrome | Lungs | Protein-arginine deiminase | Webs | Rodents | Histones | Deletion | Sepsis | post translational modification | inflammation | sepsis | hemorrhage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
7. Full Text Polydatin - a new mitochondria protector for acute severe hemorrhagic shock treatment
by Wang, Xingmin and Song, Rui and Chen, Yunyan and Zhao, Ming and Zhao, Ke-seng
Expert Opinion on Investigational Drugs, ISSN 1354-3784, 02/2013, Volume 22, Issue 2, pp. 169 - 179
Objective: The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe... 
mitochondrial injury | hemorrhagic shock | mitochondrial protector | mitochondrial permeability transition pores | polydatin | brain neuron | Brain neuron | Hemorrhagic shock | Mitochondrial protector | Mitochondrial injury | Mitochondrial permeability transition pores | Polydatin | TARGET | PERMEABILITY TRANSITION PORE | RESVERATROL | OXIDATIVE STRESS | REPERFUSION | CYCLOSPORINE-A | ARTERIAL SMOOTH-MUSCLE | PHARMACOLOGY & PHARMACY | UNDERLIES HYPOREACTIVITY | DYSFUNCTION | BRAIN | Stilbenes - administration & dosage | Rats, Wistar | Shock, Hemorrhagic - metabolism | Stilbenes - therapeutic use | Lipid Peroxides - metabolism | Protective Agents - chemistry | Stilbenes - chemistry | Parietal Lobe - metabolism | Protective Agents - therapeutic use | Shock, Hemorrhagic - drug therapy | Membrane Potential, Mitochondrial - drug effects | Mitochondria - ultrastructure | Dose-Response Relationship, Drug | Neurons - ultrastructure | Parietal Lobe - drug effects | Lipid Peroxidation - drug effects | Glucosides - chemistry | Glucosides - therapeutic use | Neurons - metabolism | Neurons - drug effects | Disease Models, Animal | Severity of Illness Index | Shock, Hemorrhagic - pathology | Acute Disease | Drugs, Chinese Herbal | Mitochondrial Membrane Transport Proteins - metabolism | Rats | Mitochondria - metabolism | Mitochondria - drug effects | Parietal Lobe - pathology | Animals | Glucosides - administration & dosage | Survival Analysis | Protective Agents - administration & dosage
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Histone deacetylase inhibitors: Isoform selectivity improves survival in a hemorrhagic shock model
by Chang, Panpan and Weykamp, Michael and Dennahy, Isabel S and Williams, Aaron M and Bhatti, Umar F and Liu, Baoling and Nikolian, Vahagn C and Li, Yongqing and Alam, Hasan B
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 05/2018, Volume 84, Issue 5, pp. 795 - 801
BACKGROUND Hemorrhage is a leading preventable cause of death. Nonselective histone deacetylase inhibitors (HDACIs), such as valproic acid (VPA), have been... 
hemorrhagic shock | isoform-selective | prosurvival pathways | valproic acid | Histone deacetylase inhibitors | SURGERY | APOPTOSIS | PHOSPHORYLATION | RESUSCITATION FLUIDS | RAT MODEL | CELL-DEATH | RECOVERY | TRAUMATIC BRAIN-INJURY | PROSURVIVAL PHENOTYPE | MOLECULAR-MECHANISMS | CRITICAL CARE MEDICINE | Shock, Hemorrhagic - pathology | Phosphorylation | Survival Rate - trends | Apoptosis - drug effects | Rats | Male | Myocardium - pathology | Random Allocation | Shock, Hemorrhagic - drug therapy | Rats, Sprague-Dawley | Animals | Myocardium - metabolism | Shock, Hemorrhagic - mortality | Valproic Acid - therapeutic use | Histone Deacetylase Inhibitors - therapeutic use | Disease Models, Animal | Divalproex | Care and treatment | Usage | Rattus | Research | Valproic acid | Hemorrhage | pro-survival pathways | histone deacetylase inhibitors
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Poor microcirculatory flow dynamics are associated with endothelial cell damage and glycocalyx shedding after traumatic hemorrhagic shock
by Naumann, David N and Hazeldine, Jon and Midwinter, Mark J and Hutchings, Sam D and Harrison, Paul
Journal of Trauma and Acute Care Surgery, ISSN 2163-0755, 01/2018, Volume 84, Issue 1, pp. 81 - 88
BACKGROUND Endothelial cell damage and glycocalyx shedding after trauma can increase the risk of inflammation, coagulopathy, vascular permeability, and death.... 
glycocalyx | trauma | microcirculation | Endothelium | hemorrhage | SURGERY | MECHANISM | SEVERELY INJURED PATIENTS | SYMPATHOADRENAL ACTIVATION | HYPOCOAGULABILITY | THROMBOMODULIN | PLASMA | INDUCED COAGULOPATHY | COAGULATION | DEGRADATION | RESUSCITATION | CRITICAL CARE MEDICINE | Biomarkers - metabolism | Shock, Hemorrhagic - pathology | Glycocalyx - pathology | Prospective Studies | Syndecan-1 - metabolism | Shock, Hemorrhagic - metabolism | Endothelial Cells - metabolism | Humans | Middle Aged | Shock, Traumatic - pathology | Male | Microscopy, Video | Microcirculation - physiology | Thrombomodulin - metabolism | Shock, Traumatic - physiopathology | Shock, Hemorrhagic - physiopathology | Adult | Female | Endothelial Cells - pathology | Shock, Traumatic - metabolism | Longitudinal Studies | Complications and side effects | Hemorrhagic shock | Research | Biological markers | Health aspects
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Trauma and hemorrhagic shock activate molecular association of 5-lipoxygenase and 5-lipoxygenase–Activating protein in lung tissue
by Nunns, Geoffrey R and Stringham, John R and Gamboni, Fabia and Moore, Ernest E and Fragoso, Miguel and Stettler, Gregory R and Silliman, Christopher C and Banerjee, Anirban
Journal of Surgical Research, ISSN 0022-4804, 09/2018, Volume 229, pp. 262 - 270
Post-traumatic lung injury following trauma and hemorrhagic shock (T/HS) is associated with significant morbidity. Leukotriene-induced inflammation has been... 
Post-traumatic lung injury | Hemorrhagic shock | Lipoxygenase | Leukotrienes | Trauma | ALOX5 | SURGERY | CLATHRIN-MEDIATED ENDOCYTOSIS | HUMAN NEUTROPHILS | MESENTERIC LYMPH | GUT | INJURY | LEUKOTRIENE B-4 | LEUKOCYTES | BIOSYNTHESIS | TEMPORAL TRENDS | MULTIPLE-ORGAN FAILURE | Shock, Hemorrhagic - pathology | Lung - pathology | Arachidonate 5-Lipoxygenase - metabolism | 5-Lipoxygenase-Activating Proteins - metabolism | Leukotrienes - immunology | Humans | Rats | Male | 5-Lipoxygenase-Activating Proteins - immunology | Acute Lung Injury - pathology | Rats, Sprague-Dawley | Arachidonate 5-Lipoxygenase - immunology | Leukotrienes - metabolism | Respiratory Distress Syndrome, Adult - immunology | Animals | Acute Lung Injury - immunology | Shock, Hemorrhagic - immunology | Lung - immunology | Disease Models, Animal | Fluorescence | Enzymes | Arachidonic acid | Analysis
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text NK1.1+ cells promote sustained tissue injury and inflammation after trauma with hemorrhagic shock
by Chen, Shuhua and Hoffman, Rosemary A and Scott, Melanie and Manson, Joanna and Loughran, Patricia and Ramadan, Mostafa and Demetris, Anthony J and Billiar, Timothy R
Journal of Leukocyte Biology, ISSN 0741-5400, 07/2017, Volume 102, Issue 1, pp. 127 - 134
NK1.1+ cell activation contributes to the persistence of inflammation leading to end organ damage in the liver and gut after HS/T. Various cell populations... 
leukocytes | cytokines | natural killer cell | T cell | Natural killer cell | Leukocytes | Cytokines | NATURAL-KILLER | MACROPHAGES | MEDIATOR | DEPLETION | IMMUNOLOGY | HEPATIC-INJURY | CELL BIOLOGY | SYSTEMIC INFLAMMATION | ORGAN INJURY | NK CELLS | LIVER-INJURY | INFECTION | HEMATOLOGY | Shock, Hemorrhagic - pathology | Wounds and Injuries - pathology | Wounds and Injuries - blood | Alanine Transaminase - blood | Aspartate Aminotransferases - immunology | Wounds and Injuries - immunology | NK Cell Lectin-Like Receptor Subfamily B - immunology | Shock, Hemorrhagic - blood | NK Cell Lectin-Like Receptor Subfamily B - blood | Animals | Antigens, Ly - immunology | Aspartate Aminotransferases - blood | Killer Cells, Natural - immunology | Mice | Killer Cells, Natural - metabolism | Shock, Hemorrhagic - immunology | Alanine Transaminase - immunology | Antigens, Ly - blood | Cytokines - blood | Cytokines - immunology | Flow cytometry | Populations | Liver | Transaminase | Lymphocytes T | Macrophages | Hemorrhage | Interleukin 6 | Cell activation | Rodents | Natural killer cells | Damage | Injuries | Resuscitation | Alanine | Leukocytes (neutrophilic) | Histology | Inflammation | Tumor necrosis factor-α | Trauma | Cytometry | Depletion | Hepatocytes | γ-Interferon | Alanine transaminase | Plasma levels | Interferon | Aspartate aminotransferase | Monocyte chemoattractant protein 1 | Inflammation, Extracellular Mediators, & Effector Molecules
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Mechanisms Involved in Secondary Cardiac Dysfunction in Animal Models of Trauma and Hemorrhagic Shock
by Wilson, Nick M and Wall, Johanna and Naganathar, Veena and Brohi, Karim and De’Ath, Henry D
SHOCK, ISSN 1073-2322, 10/2017, Volume 48, Issue 4, pp. 401 - 410
ABSTRACTClinical evidence reveals the existence of a trauma-induced secondary cardiac injury (TISCI) that is associated with poor patient outcomes. The... 
Mechanisms | Secondary | Inflammation | Dysfunction | Trauma | Cardiac | trauma | ESTROGEN RECEPTOR-BETA | SURGERY | ACTIVATED PROTEIN-KINASE | MESENTERIC LYMPH | NECROSIS-FACTOR-ALPHA | MEDIATED CARDIOPROTECTION | dysfunction | secondary | TOLL-LIKE RECEPTOR-4 | CARDIOMYOCYTE APOPTOSIS | inflammation | PERIPHERAL VASCULAR DISEASE | TNF-ALPHA | HEMATOLOGY | mechanisms | NF-KAPPA-B | UP-REGULATION | CRITICAL CARE MEDICINE | Heart Injuries - pathology | Shock, Hemorrhagic - pathology | Shock, Hemorrhagic - complications | Shock, Hemorrhagic - metabolism | Wounds and Injuries - pathology | Heart Injuries - metabolism | Humans | Wounds and Injuries - complications | Myocardium - pathology | Wounds and Injuries - metabolism | Animals | Heart Injuries - etiology | Myocardium - metabolism | Disease Models, Animal
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
13. Full Text Loss of Syndecan-1 Abrogates the Pulmonary Protective Phenotype Induced by Plasma After Hemorrhagic Shock
by Wu, Feng and Peng, Zhanglong and Park, Pyong Woo and Kozar, Rosemary A
SHOCK, ISSN 1073-2322, 09/2017, Volume 48, Issue 3, pp. 340 - 345
ABSTRACTSyndecan-1 (Sdc1) is considered a biomarker of injury to the endothelial glycocalyx following hemorrhagic shock, with shedding of Sdc1 deleterious.... 
fresh frozen plasma | rodent model of hemorrhagic shock | syndecan-1 null mice | syndecan-4 | Endothelial cell permeability | MORTALITY | SURGERY | INJURY | ISCHEMIA | RECEPTOR | ENDOTHELIAL GLYCOCALYX DEGRADATION | INFLAMMATION | PERIPHERAL VASCULAR DISEASE | HEPARAN-SULFATE | MICE | HEMATOLOGY | FRESH-FROZEN PLASMA | TRAUMA PATIENTS | CRITICAL CARE MEDICINE | Plasma | Shock, Hemorrhagic - pathology | Lung - pathology | Syndecan-1 - metabolism | Shock, Hemorrhagic - metabolism | Endothelial Cells - metabolism | Syndecan-1 - genetics | Cells, Cultured | Shock, Hemorrhagic - therapy | Mice, Knockout | Animals | Shock, Hemorrhagic - genetics | Lung - metabolism | Mice | Endothelial Cells - pathology | Resuscitation
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
14. Full Text Inhibition of IκB kinase attenuates the organ injury and dysfunction associated with hemorrhagic shock
by Sordi, Regina and Chiazza, Fausto and Johnson, Florence L and Patel, Nimesh S. A and Brohi, Karim and Collino, Massimo and Thiemermann, Christoph
Molecular Medicine, ISSN 1076-1551, 06/2015, Volume 21, Issue 1, pp. 563 - 575
Nuclear factor-kappa B (NF-kappa B) activation is widely implicated in multiple organ failure (MOF); however, a direct inhibitor of I kappa B kinase (IKK),... 
MEDICINE, RESEARCH & EXPERIMENTAL | ERYTHROPOIETIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | REPERFUSION INJURY | LUNG INJURY | HYDROGEN-SULFIDE | SEPSIS | INTERLEUKIN-10 | PROTECTS | CELL BIOLOGY | SELECTIVE INHIBITOR | PATHWAY | INFLAMMATORY RESPONSE | Liver - pathology | Phosphorylation | Shock, Hemorrhagic - complications | Kidney - pathology | Humans | Shock, Hemorrhagic - therapy | Multiple Organ Failure - therapy | I-kappa B Proteins - genetics | Liver - injuries | Kidney - metabolism | I-kappa B Proteins - antagonists & inhibitors | Multiple Organ Failure - complications | Multiple Organ Failure - pathology | Shock, Hemorrhagic - pathology | NF-KappaB Inhibitor alpha | Lipopolysaccharides - toxicity | Signal Transduction | Liver - metabolism | Rats | Multiple Organ Failure - genetics | Kidney - injuries | Lung Injury - genetics | Animals | NF-kappa B - genetics | Shock, Hemorrhagic - genetics
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights