X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (13338) 13338
Publication (1241) 1241
Newsletter (120) 120
Book Review (113) 113
Book / eBook (81) 81
Book Chapter (71) 71
Conference Proceeding (16) 16
Magazine Article (12) 12
Dissertation (10) 10
Data Set (5) 5
Transcript (4) 4
Newspaper Article (2) 2
Paper (2) 2
Trade Publication Article (2) 2
Web Resource (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (7657) 7657
septic shock (7653) 7653
humans (6842) 6842
male (6057) 6057
index medicus (4829) 4829
sepsis (4546) 4546
female (3832) 3832
mice (2875) 2875
rats (2699) 2699
critical care medicine (2363) 2363
middle aged (2051) 2051
shock, septic - metabolism (1947) 1947
inflammation (1878) 1878
aged (1673) 1673
immunology (1620) 1620
adult (1616) 1616
disease models, animal (1538) 1538
tumor-necrosis-factor (1437) 1437
surgery (1418) 1418
shock, septic - physiopathology (1416) 1416
shock (1414) 1414
mortality (1373) 1373
cytokines (1328) 1328
research (1309) 1309
severe sepsis (1122) 1122
endotoxin (1085) 1085
lipopolysaccharide (1067) 1067
tumor necrosis factor-alpha - metabolism (1065) 1065
sepsis - metabolism (1047) 1047
hematology (1018) 1018
rats, sprague-dawley (1014) 1014
shock, septic - drug therapy (1006) 1006
lipopolysaccharides - pharmacology (992) 992
prospective studies (981) 981
expression (966) 966
pharmacology & pharmacy (958) 958
peripheral vascular disease (931) 931
health aspects (930) 930
nitric oxide (918) 918
biochemistry & molecular biology (915) 915
mice, inbred c57bl (914) 914
time factors (895) 895
cell biology (884) 884
shock, septic - blood (874) 874
analysis (825) 825
activation (808) 808
research article (771) 771
lipopolysaccharides (767) 767
physiology (767) 767
rats, wistar (760) 760
infection (754) 754
cells, cultured (749) 749
hemodynamics (740) 740
nitric-oxide synthase (720) 720
metabolism (717) 717
medicine (700) 700
physiological aspects (700) 700
critical illness (681) 681
cytokines - metabolism (681) 681
lipopolysaccharides - toxicity (676) 676
shock, septic - immunology (661) 661
sepsis - physiopathology (660) 660
sepsis - blood (656) 656
medicine, research & experimental (651) 651
liver - metabolism (634) 634
oxidative stress (634) 634
apoptosis (633) 633
nitric-oxide (630) 630
care and treatment (629) 629
nitric oxide - metabolism (613) 613
critically-ill patients (605) 605
prognosis (598) 598
rodents (592) 592
sepsis - drug therapy (586) 586
aged, 80 and over (585) 585
macrophages (580) 580
cells (576) 576
critical care (572) 572
dogs (570) 570
anesthesiology (569) 569
infectious diseases (567) 567
proteins (550) 550
escherichia coli (531) 531
multidisciplinary sciences (528) 528
risk factors (525) 525
sepsis - immunology (521) 521
dose-response relationship, drug (519) 519
microbiology (514) 514
shock, septic - etiology (512) 512
shock, septic - mortality (510) 510
injury (503) 503
signal transduction (500) 500
endotoxemia (498) 498
blood pressure (497) 497
nf-kappa-b (496) 496
oxygen consumption (495) 495
mice, knockout (492) 492
in-vivo (489) 489
article (488) 488
abridged index medicus (487) 487
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (68) 68
Online Resources - Online (3) 3
Collection Dvlpm't (Acquisitions) - Closed Orders (2) 2
Collection Dvlpm't (Acquisitions) - Vendor file (1) 1
Lakeridge Health Sciences - Oshawa (1) 1
Providence Healthcare - Stacks (1) 1
Scarborough Hospital - General (1) 1
St. Michael's Hospital - Stacks (1) 1
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (13019) 13019
German (138) 138
Japanese (87) 87
Chinese (83) 83
Russian (80) 80
French (63) 63
Spanish (42) 42
Polish (25) 25
Italian (18) 18
Hungarian (10) 10
Romanian (9) 9
Dutch (8) 8
Portuguese (8) 8
Czech (7) 7
Bulgarian (5) 5
Danish (3) 3
Korean (3) 3
Norwegian (3) 3
Croatian (2) 2
Ukrainian (2) 2
Finnish (1) 1
Hebrew (1) 1
Serbian (1) 1
Swedish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Nature Immunology, ISSN 1529-2908, 02/2016, Volume 17, Issue 2, pp. 140 - 149
Innate sensing of pathogens initiates inflammatory cytokine responses that need to be tightly controlled. We found here that after engagement of Toll-like... 
PATHWAYS | INTERFERON | ACTIVATION | SUMO | BETA-GENE | IFN-GAMMA | NEGATIVE REGULATION | ENHANCER | MICE | IMMUNOLOGY | UP-REGULATION | Chromatin - metabolism | Dendritic Cells - immunology | Gene Expression Profiling | Genetic Loci | Shock, Septic - immunology | Lipopolysaccharides - immunology | Shock, Septic - metabolism | Inflammation - metabolism | Inflammation Mediators - metabolism | Toll-Like Receptors - metabolism | Dendritic Cells - metabolism | Disease Models, Animal | Receptor, Interferon alpha-beta - metabolism | Shock, Septic - genetics | Sumoylation - genetics | Disease Resistance | Disease Susceptibility | Cytokines - metabolism | Signal Transduction | Immunomodulation | Gene Expression Regulation | Inflammation - virology | Inflammation - immunology | Immunity, Innate | Mice, Knockout | Animals | Enhancer Elements, Genetic | Interferon-beta - metabolism | Regulatory Elements, Transcriptional | Sumoylation - immunology | Inflammation - genetics | Protein Binding | Mice | SUMO-1 Protein - metabolism | Chromatin - genetics | Analysis | Influence | Interferon | Inflammation | Research | Biological response modifiers | Gene expression | Health aspects | Risk factors | Shock, Septic/metabolism | Inflammation Mediators/metabolism | Sumoylation/immunology | Interferon-beta/metabolism | Dendritic Cells/metabolism | Inflammation/virology | Inflammation/immunology | Life Sciences | Immunology | Receptor, Interferon alpha-beta/metabolism | Inflammation/genetics | SUMO-1 Protein/metabolism | Cytokines/metabolism | Sumoylation/genetics | Chromatin/metabolism | Inflammation/metabolism | Toll-Like Receptors/metabolism | Lipopolysaccharides/immunology | Shock, Septic/immunology | Chromatin/genetics | Shock, Septic/genetics | Dendritic Cells/immunology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 539 - 550
In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns... 
MEDICINE, RESEARCH & EXPERIMENTAL | DANGER SIGNALS | STERILE INFLAMMATION | CHROMATIN PROTEIN HMGB1 | IN-VIVO | SEPTIC SHOCK | MOBILITY GROUP BOX-1 | RECEPTOR | DEFICIENT MICE | CELL-DEATH | TRANSGENIC MICE | Acetaminophen - adverse effects | Inflammation - chemically induced | Leukocyte Elastase - metabolism | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Tumor Necrosis Factor-alpha - genetics | Analgesics, Non-Narcotic - pharmacology | Hepatocytes - pathology | Hepatocytes - metabolism | Neutrophil Infiltration | fas Receptor - metabolism | Necrosis - pathology | HMGB1 Protein - genetics | Shock, Septic - metabolism | Inflammation - metabolism | Acetaminophen - pharmacology | Analgesics, Non-Narcotic - adverse effects | HMGB1 Protein - metabolism | fas Receptor - genetics | Chemical and Drug Induced Liver Injury - pathology | Neutrophils - metabolism | Receptor for Advanced Glycation End Products | Neutrophils - pathology | Shock, Septic - genetics | Shock, Septic - pathology | Lipopolysaccharides - toxicity | Macrophages - pathology | Shock, Septic - chemically induced | Leukocyte Elastase - genetics | Necrosis - metabolism | Chemical and Drug Induced Liver Injury - genetics | Mice, Knockout | Necrosis - chemically induced | Macrophages - metabolism | Animals | Chemical and Drug Induced Liver Injury - metabolism | Inflammation - genetics | Mice | Necrosis - genetics | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Physiological aspects | Causes of | Inflammation | Genetic aspects | Cell death | Necrosis | Chromosomal proteins | Mass spectrometry | Analysis | Proteins | Studies | Rodents | Mortality | Gangrene | Homeostasis | Mitochondrial DNA | Laboratory animals | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Journal Article
Critical Care, ISSN 1364-8535, 07/2010, Volume 14, Issue 4, pp. R126 - R126
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2016, Volume 113, Issue 41, pp. 11543 - 11548
Journal Article
FASEB Journal, ISSN 0892-6638, 02/2012, Volume 26, Issue 2, pp. 722 - 729
Journal Article
Journal Article
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 12/2010, Volume 182, Issue 12, pp. 1506 - 1515
Journal Article
Critical Care Medicine, ISSN 0090-3493, 01/2007, Volume 35, Issue 1, pp. 118 - 126
OBJECTIVE:Sepsis is associated with an increase in reactive oxygen species and low endogenous antioxidative capacity. We postulated that high-dose... 
Antioxidants | Organ failure | Sepsis | Septic shock | Systemic inflammatory response syndrome | Selenium | CONTROLLED-TRIAL | septic shock | antioxidants | NECROSIS-FACTOR-ALPHA | GLUTATHIONE SYNTHESIS | DEFICIENCY INCREASES | FREE-RADICALS | TRACE-ELEMENT | WHOLE-BLOOD | systemic inflammatory response syndrome | selenium | ACUTE-PHASE | organ failure | NITRIC-OXIDE | CRITICALLY-ILL PATIENTS | sepsis | CRITICAL CARE MEDICINE | Prospective Studies | Humans | Middle Aged | Male | Sepsis - complications | Shock, Septic - metabolism | Sepsis - drug therapy | Sodium Selenite - metabolism | Sepsis - metabolism | Shock, Septic - drug therapy | Aged, 80 and over | Adult | Female | Severity of Illness Index | Systemic Inflammatory Response Syndrome - metabolism | Double-Blind Method | Hospital Mortality | Glutathione Peroxidase - blood | Kaplan-Meier Estimate | Shock, Septic - complications | Survival Rate | Treatment Outcome | Sodium Selenite - pharmacology | Shock, Septic - mortality | Germany - epidemiology | Sepsis - mortality | Disseminated Intravascular Coagulation - etiology | Multiple Organ Failure - etiology | Aged | Systemic Inflammatory Response Syndrome - complications | Infusions, Intravenous | Drug Monitoring | Systemic Inflammatory Response Syndrome - drug therapy | APACHE | Systemic Inflammatory Response Syndrome - mortality | Sodium Selenite - therapeutic use
Journal Article