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gene expression regulation, bacterial (94) 94
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siderophores - pharmacology (61) 61
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bacterial outer membrane proteins - metabolism (59) 59
escherichia coli - genetics (56) 56
bacterial outer membrane proteins - genetics (55) 55
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siderophores - genetics (53) 53
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antibiotics (49) 49
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Journal of Experimental Medicine, ISSN 0022-1007, 2014, Volume 211, Issue 6, pp. 1197 - 1213
Competition for iron influences host-pathogen interactions. Pathogens secrete small iron binding moieties, siderophores, to acquire host iron. In response, the... 
MEDICINE, RESEARCH & EXPERIMENTAL | LIPOCALIN | CELLS | ESCHERICHIA-COLI | ENTEROBACTIN | SALMONELLA-TYPHIMURIUM | NEUTROPHIL GELATINASE | HEPCIDIN | IRON ACQUISITION | MICE | IMMUNOLOGY | BINDING | Candidiasis - genetics | Oncogene Proteins - genetics | Gentisates - metabolism | Immunity, Innate - genetics | Immunoblotting | Male | Bacterial Infections - genetics | RNA Interference | Lipocalins - genetics | Candida albicans - physiology | Transcription Factors - immunology | Carrier Proteins - immunology | Enterobactin - metabolism | Bacterial Outer Membrane Proteins - immunology | Hydroxybutyrate Dehydrogenase - immunology | Oncogene Proteins - metabolism | Candida albicans - immunology | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Cell Surface - immunology | Mice, Knockout | Gentisates - immunology | Bacterial Outer Membrane Proteins - metabolism | Escherichia coli - genetics | Lipocalin-2 | Lipocalins - immunology | Staphylococcus aureus - immunology | Mice | Bacterial Infections - metabolism | Positive Regulatory Domain I-Binding Factor 1 | Receptors, Cell Surface - genetics | Staphylococcus aureus - physiology | Acute-Phase Proteins - genetics | Mutation - immunology | Hydroxybutyrate Dehydrogenase - genetics | Bacterial Infections - immunology | Female | Candidiasis - immunology | Escherichia coli - physiology | Oncogene Proteins - immunology | Bacterial Outer Membrane Proteins - genetics | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Siderophores - metabolism | Mice, Inbred C57BL | Kaplan-Meier Estimate | Escherichia coli - immunology | Receptors, Cell Surface - metabolism | Transcription Factors - genetics | Hydroxybutyrate Dehydrogenase - metabolism | Transcription Factors - metabolism | Candidiasis - metabolism | Carrier Proteins - genetics | Immunity, Innate - immunology | Enterobactin - immunology | Animals | Carrier Proteins - metabolism | Siderophores - immunology | Acute-Phase Proteins - immunology
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 05/2013, Volume 190, Issue 9, pp. 4692 - 4706
Lipocalin 24p3 (24p3) is a neutrophil secondary granule protein. 24p3 is also a siderocalin, which binds several bacterial siderophores. It was therefore... 
LISTERIA-MONOCYTOGENES | IMMUNE-RESPONSE | ACUTE-PHASE PROTEIN | CANDIDA-ALBICANS | LIPOCALIN 24P3 | HOST-DEFENSE | RESISTANCE | MONOCLONAL-ANTIBODY | IRON | DEFICIENT MICE | IMMUNOLOGY | NIH 3T3 Cells | Oncogene Proteins - genetics | Cytoskeletal Proteins - genetics | Cytoskeleton - immunology | Acute-Phase Proteins - genetics | Phagocytosis - genetics | Respiratory Burst - immunology | Bacterial Infections - genetics | Disease Susceptibility - immunology | Bacterial Infections - immunology | Lipocalins - genetics | Cytoskeletal Proteins - metabolism | rho GTP-Binding Proteins - immunology | Chemotaxis - immunology | Neutrophils - metabolism | Oncogene Proteins - immunology | Chemokines - immunology | Lipocalins - metabolism | Cell Line | Acute-Phase Proteins - metabolism | Siderophores - metabolism | rho GTP-Binding Proteins - genetics | Mice, Inbred C57BL | Cytoskeleton - genetics | Neutrophils - immunology | Oncogene Proteins - metabolism | Phagocytosis - immunology | Chemokines - genetics | Chemotaxis - genetics | Mice, Knockout | Animals | Cytoskeletal Proteins - immunology | Lipocalin-2 | Lipocalins - immunology | rho GTP-Binding Proteins - metabolism | Cytoskeleton - metabolism | Chemokines - metabolism | Mice | MicroRNAs - genetics | Respiratory Burst - genetics | Siderophores - immunology | Acute-Phase Proteins - immunology | Bacterial Infections - metabolism | Candida albicans | Listeria monocytogenes | neutrophils | Lipocalin 24p3 | Staphylococcus aureus
Journal Article
PLoS ONE, ISSN 1932-6203, 2012, Volume 7, Issue 11, p. e50052
Pulmonary tuberculosis (TB), caused by the intracellular bacteria Mycobacterium tuberculosis, is a worldwide disease that continues to kill more than 1.5... 
IMMUNE-RESPONSE | LUNG | CELLS | TUBERCULOSIS | MULTIDISCIPLINARY SCIENCES | HOST-DEFENSE | INNATE | RESISTANCE | MICE | GELATINASE-ASSOCIATED LIPOCALIN | EXPRESSION | Oncogene Proteins - genetics | Mycobacterium bovis - immunology | Mycobacterium tuberculosis - immunology | Tuberculosis - microbiology | Acute-Phase Proteins - genetics | Mycobacterium Infections - immunology | Inflammation - metabolism | Lipocalins - genetics | Mycobacterium Infections - microbiology | Granuloma, Respiratory Tract - microbiology | Acute-Phase Proteins - deficiency | Neutrophils - microbiology | Oncogene Proteins - immunology | Tuberculosis - metabolism | Macrophages, Alveolar - immunology | Granuloma, Respiratory Tract - immunology | Acute Disease | Gene Expression | Inflammation - microbiology | Macrophages, Alveolar - microbiology | T-Lymphocytes - microbiology | Siderophores - metabolism | Mice, Inbred C57BL | Neutrophils - immunology | Chemokine CXCL9 - antagonists & inhibitors | Chemokine CXCL9 - immunology | Inflammation - immunology | Mycobacterium Infections - metabolism | Tuberculosis - veterinary | Iron - metabolism | Mice, Knockout | Tuberculosis - immunology | Inflammation - veterinary | Animals | Granuloma, Respiratory Tract - metabolism | Granuloma, Respiratory Tract - veterinary | Lipocalin-2 | Lipocalins - immunology | Oncogene Proteins - deficiency | T-Lymphocytes - immunology | Mice | Mycobacterium Infections - veterinary | Chronic Disease | Acute-Phase Proteins - immunology | Cell Movement | Infection | Proteins | Tuberculosis | Bacterial infections | Lung diseases | Inflammation | B cells | T cells | Health aspects | Protein binding | Pediatrics | Granuloma | Siderophores | Animal models | Inflammatory response | Lymphocytes T | Iron | Infections | Macrophages | Experiments | Accumulation | Recruitment | Immunology | Granulocyte colony-stimulating factor | Lymphocytes | Health care networks | Rodents | Bacteria | Sequestering | Alveoli | Drug dosages | Public health | Medical research | Cytokines | Lipocalin | Neutrophils | Rheumatology | BCG | Breast cancer | Medicine | Infectious diseases | Lungs | Regulatory mechanisms (biology) | Chemokines
Journal Article
Infection and Immunity, ISSN 0019-9567, 2015, Volume 83, Issue 12, pp. 4639 - 4652
Bordetella bronchiseptica can use catecholamines to obtain iron from transferrin and lactoferrin via uptake pathways involving the BfrA, BfrD, and BfrE outer... 
IRON TRANSPORT | ALCALIGIN | INFECTIOUS DISEASES | GRAM-NEGATIVE BACTERIA | DIFFERENTIAL EXPRESSION | OUTER-MEMBRANE PROTEIN | SIDEROPHORE UTILIZATION | PERTUSSIS | ESCHERICHIA-COLI | BRONCHISEPTICA | IMMUNOLOGY | STATISTICAL-MODEL | Bordetella Infections - immunology | Bordetella Infections - microbiology | Catecholamines - metabolism | Species Specificity | Bordetella bronchiseptica - genetics | Humans | Virulence | Bordetella pertussis - immunology | Receptors, Catecholamine - immunology | Bordetella pertussis - metabolism | Bordetella bronchiseptica - immunology | Bacterial Proteins - immunology | Receptors, Catecholamine - genetics | Transcription Factors - immunology | Bacterial Outer Membrane Proteins - genetics | Bordetella Infections - pathology | Bacterial Outer Membrane Proteins - immunology | Siderophores - metabolism | Bacterial Proteins - genetics | Bordetella pertussis - genetics | Iron - immunology | Transcription Factors - genetics | Bordetella bronchiseptica - metabolism | Iron - metabolism | Receptors, Cell Surface - immunology | Catecholamines - immunology | Animals | Bordetella pertussis - pathogenicity | Mice | Mice, Inbred BALB C | Gene Expression Regulation, Bacterial | Protein Isoforms - immunology | Siderophores - immunology | Bordetella bronchiseptica - pathogenicity | Protein Isoforms - genetics | Receptors, Cell Surface - genetics | Molecular Pathogenesis
Journal Article
PLoS Pathogens, ISSN 1553-7366, 09/2009, Volume 5, Issue 9, pp. e1000586 - e1000586
Uncomplicated infections of the urinary tract, caused by uropathogenic Escherichia coli, are among the most common diseases requiring medical intervention. A... 
UROPATHOGENIC ESCHERICHIA-COLI | PHASE-2 CLINICAL-TRIAL | UROLOGIC DISEASES | MICROBIOLOGY | DELTA-T-CELLS | AMERICA PROJECT | VACCINE CANDIDATE | VIROLOGY | EXTRAINTESTINAL PATHOGENIC ISOLATE | PYELONEPHRITIS | SIDEROPHORE RECEPTOR | RESOURCE USE | PARASITOLOGY | Recombinant Fusion Proteins - immunology | Spleen - immunology | Escherichia coli Infections - prevention & control | Antigens, Bacterial - immunology | Immunoglobulin Class Switching - immunology | Interferon-gamma - metabolism | Urinary Tract Infections - prevention & control | Immunoglobulin A, Secretory - metabolism | Antigens, Bacterial - genetics | Recombinant Fusion Proteins - metabolism | Immunoglobulin A, Secretory - urine | Statistics, Nonparametric | Mice, Inbred CBA | Female | Escherichia coli Proteins - immunology | Antibodies, Bacterial - blood | Cells, Cultured | Escherichia coli - immunology | Escherichia coli Proteins - metabolism | Spleen - cytology | Administration, Intranasal | Escherichia coli Vaccines - administration & dosage | Interleukin-17 - metabolism | Animals | Spleen - metabolism | Escherichia coli Proteins - genetics | Recombinant Fusion Proteins - genetics | Antibodies, Bacterial - immunology | Escherichia coli Infections - immunology | Mice | Escherichia coli Vaccines - immunology | Antigens, Bacterial - metabolism | Urinary Tract Infections - immunology | Proteins | Confidence intervals | Bacterial infections | E coli | Pathogenesis | Bladder | Excretory system | Bacteria | Infections | Vaccines | Urogenital system | Binding sites
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e104803 - e104803
Journal Article
Cell Host & Microbe, ISSN 1931-3128, 04/2013, Volume 13, Issue 4, pp. 406 - 416
Journal Article
Journal Article
Journal Article
Vaccine, ISSN 0264-410X, 06/2018, Volume 36, Issue 27, pp. 3949 - 3959
O157:H7 is a zoonotic pathogen of global importance and the serotype of Shiga toxin-producing (STEC) most frequently associated with Hemolytic Uremic Syndrome... 
EHEC | Antigens | STEC | Vaccine | O157:H7 | Protection | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | POLYMERIC BACTERIAL PROTEIN | IMMUNOLOGY | B-SUBUNIT | BEEF-CATTLE | SIDEROPHORE RECEPTOR | GENETIC-LOCUS | O157-H7 | INFECTION | INTRAEPITHELIAL LYMPHOCYTES | Escherichia coli Infections - prevention & control | Immunity, Humoral - immunology | Adhesins, Bacterial - genetics | Humans | Male | Vaccination - veterinary | Vaccines, Synthetic - immunology | Shiga Toxin 2 - immunology | Shiga Toxin 2 - genetics | Feces - microbiology | Bacterial Shedding | Cattle | Intestinal Mucosa - immunology | Escherichia coli Infections - veterinary | Escherichia coli Proteins - immunology | Hemolytic-Uremic Syndrome - prevention & control | Antibodies, Bacterial - blood | Bacterial Outer Membrane Proteins - genetics | Bacterial Outer Membrane Proteins - immunology | Vaccines, Synthetic - therapeutic use | Escherichia coli Vaccines - administration & dosage | Animals | Escherichia coli Proteins - genetics | Escherichia coli Vaccines - therapeutic use | Vaccines, Synthetic - administration & dosage | Adhesins, Bacterial - immunology | Escherichia coli Vaccines - immunology | Escherichia coli O157 - immunology | Antibodies, Neutralizing - blood | Zoonoses - prevention & control | Vaccines | Vaccination | Contamination | Shedding | Immunomagnetic separation | Shiga toxin | Mucosa | Antibodies | Infections | Experiments | Proteins | E coli | Intestine | Bacteria | Recombinant | Milk | Immune system | Immunization | Food contamination & poisoning | Statistical analysis | Immune response | Hemolytic uremic syndrome | Cytokines | Calves | Intimin | Immunosuppression | Lumazine synthase
Journal Article