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Journal Article
CURRENT NEUROPHARMACOLOGY, ISSN 1570-159X, 12/2008, Volume 6, Issue 4, pp. 344 - 366
Journal Article
Journal Article
Journal Article
Annals of Neurology, ISSN 0364-5134, 11/2010, Volume 68, Issue 5, pp. 639 - 649
Journal Article
Investigative Ophthalmology and Visual Science, ISSN 0146-0404, 01/2011, Volume 52, Issue 1, pp. 527 - 540
Journal Article
Chemistry & Biodiversity, ISSN 1612-1872, 03/2019, Volume 16, Issue 3, pp. e1800599 - n/a
Journal Article
BIOORGANIC & MEDICINAL CHEMISTRY, ISSN 0968-0896, 04/2013, Volume 21, Issue 7, pp. 1844 - 1856
The direct C-H-bond arylation of the complex spirocyclic lactones 13, 14, and 18 allows the introduction of diverse aryl moieties in the last step of the... 
CATALYSIS | CHEMISTRY, MEDICINAL | PROTEIN | Hydrophobic pocket | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | C-H-bond arylation of complex thiophenes | DFT calculations | HETEROARENES | LIGANDS | CLONING | PHARMACOLOGY | THIOPHENES | Spirocyclic lactones | BINDING | EXPRESSION | sigma Ligands
Journal Article
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, ISSN 0223-5234, 09/2019, Volume 177, pp. 47 - 62
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2013, Volume 168, Issue 6, pp. 1445 - 1455
Background and Purpose The Sigma‐1 receptor (Sig1R) impacts on calcium ion signalling and has a plethora of ligands. This study investigated Sig1R and its... 
cationic channels | endothelial cells | histamine | calcium channels | vascular endothelial growth factor | hydrogen peroxide | Sigma‐1 receptor | TRP channels | Sigma-1 receptor | ACTIVATION | ANGIOGENESIS | DEPENDENCE | INTRACELLULAR CA2 | CALCIUM | PHARMACOLOGY & PHARMACY | Endothelium, Vascular - cytology | Humans | Endothelium, Vascular - drug effects | Protein Transport - drug effects | Receptors, sigma - antagonists & inhibitors | Vascular Endothelial Growth Factor A - metabolism | Histamine - metabolism | RNA Interference | Membrane Transport Modulators - pharmacology | HEK293 Cells | Receptors, sigma - metabolism | TRPC Cation Channels - genetics | Membrane Potentials - drug effects | Recombinant Proteins - metabolism | Recombinant Proteins - antagonists & inhibitors | Cells, Cultured | Receptors, sigma - agonists | Receptors, sigma - genetics | TRPC Cation Channels - antagonists & inhibitors | Patch-Clamp Techniques | TRPM Cation Channels - antagonists & inhibitors | Calcium Signaling - drug effects | Endothelium, Vascular - metabolism | TRPC Cation Channels - metabolism | TRPM Cation Channels - genetics | Ligands | RNA, Small Interfering | TRPM Cation Channels - metabolism | Kinetics | Fluorescence | Histamine | Calcium channels | Hydrogen peroxide | Vascular endothelial growth factor | Endothelium | Research Papers
Journal Article