X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (244468) 244468
Book Review (40155) 40155
Publication (33274) 33274
Newspaper Article (1956) 1956
Book Chapter (1502) 1502
Conference Proceeding (868) 868
Book / eBook (313) 313
Newsletter (266) 266
Dissertation (191) 191
Report (118) 118
Reference (79) 79
Magazine Article (58) 58
Data Set (28) 28
Web Resource (25) 25
Trade Publication Article (15) 15
Paper (10) 10
Presentation (7) 7
Streaming Video (6) 6
Government Document (5) 5
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (223133) 223133
animals (143501) 143501
humans (137520) 137520
signal transduction (115038) 115038
signal transduction - drug effects (85655) 85655
mice (64879) 64879
male (47436) 47436
cell biology (46174) 46174
biochemistry & molecular biology (43462) 43462
apoptosis (39283) 39283
rats (37641) 37641
proteins (37415) 37415
phosphorylation (36279) 36279
female (36070) 36070
expression (34529) 34529
signal transduction - physiology (33119) 33119
activation (32490) 32490
oncology (32106) 32106
cells, cultured (31474) 31474
cell line, tumor (30057) 30057
cancer (28915) 28915
gene expression (28810) 28810
research (26662) 26662
kinases (25209) 25209
apoptosis - drug effects (23338) 23338
cell line (21954) 21954
article (21656) 21656
research article (20916) 20916
physiological aspects (20305) 20305
analysis (20180) 20180
pharmacology & pharmacy (19999) 19999
cells (19811) 19811
multidisciplinary sciences (19276) 19276
neurosciences (19172) 19172
inflammation (18096) 18096
medicine (18044) 18044
signal-transduction (17638) 17638
rodents (17519) 17519
immunology (17236) 17236
cell proliferation - drug effects (17077) 17077
gene-expression (17063) 17063
health aspects (16692) 16692
oxidative stress (16621) 16621
dose-response relationship, drug (16014) 16014
genetic aspects (15683) 15683
biology (15645) 15645
mice, inbred c57bl (15202) 15202
inhibition (15144) 15144
physiology (15120) 15120
science (14832) 14832
rats, sprague-dawley (13864) 13864
enzyme inhibitors - pharmacology (13665) 13665
cellular signal transduction (13460) 13460
cell proliferation (13138) 13138
blotting, western (12952) 12952
disease models, animal (12764) 12764
nf-kappa-b (12755) 12755
in-vitro (12750) 12750
mutation (12628) 12628
phosphorylation - drug effects (12552) 12552
proto-oncogene proteins c-akt - metabolism (12503) 12503
time factors (12296) 12296
signaling (12279) 12279
signal transduction - genetics (12203) 12203
antineoplastic agents - pharmacology (11765) 11765
medicine, research & experimental (11752) 11752
in-vivo (11670) 11670
growth (11461) 11461
biochemistry (11450) 11450
nf-kappa b - metabolism (11336) 11336
endocrinology & metabolism (11326) 11326
tumors (11010) 11010
abridged index medicus (10969) 10969
genes (10937) 10937
cytokines (10679) 10679
cell survival - drug effects (10670) 10670
care and treatment (10617) 10617
transfection (10529) 10529
receptor (10472) 10472
models, biological (10258) 10258
phosphatidylinositol 3-kinases - metabolism (10193) 10193
proliferation (10042) 10042
cell cycle (9973) 9973
mice, knockout (9898) 9898
studies (9848) 9848
pathway (9815) 9815
rna, messenger - metabolism (9808) 9808
protein (9607) 9607
calcium - metabolism (9530) 9530
gene expression regulation - drug effects (9502) 9502
gene expression regulation (9385) 9385
protein binding (9304) 9304
metastasis (9285) 9285
metabolism (9086) 9086
development and progression (9084) 9084
receptors (9076) 9076
reactive oxygen species - metabolism (8872) 8872
differentiation (8815) 8815
transcription factors (8555) 8555
ligands (8448) 8448
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (161) 161
Online Resources - Online (32) 32
UofT at Mississauga - Stacks (26) 26
Collection Dvlpm't (Acquisitions) - Vendor file (22) 22
Collection Dvlpm't (Acquisitions) - Closed Orders (19) 19
UofT at Scarborough - Stacks (12) 12
Engineering & Comp. Sci. - Stacks (7) 7
UTL at Downsview - May be requested (6) 6
Earth Sciences (Noranda) - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Chemistry (A D Allen) - Stacks (2) 2
Robarts - Stacks (2) 2
Baycrest Hospital - Stacks (1) 1
Gerstein Science - Missing (1) 1
OISE - Missing (1) 1
OISE - Stacks (1) 1
St. Michael's College (John M. Kelly) - 3rd Floor (1) 1
Sunnybrook Health Sciences Centre - Online (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (244969) 244969
Chinese (1427) 1427
Japanese (409) 409
Russian (276) 276
German (194) 194
French (169) 169
Spanish (69) 69
Polish (51) 51
Hungarian (35) 35
Ukrainian (27) 27
Swedish (15) 15
Portuguese (13) 13
Italian (12) 12
Korean (7) 7
Norwegian (6) 6
Danish (5) 5
Turkish (5) 5
Dutch (4) 4
Hebrew (4) 4
Czech (3) 3
Slovak (2) 2
Amharic (1) 1
Finnish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The Journal of Cell Biology, ISSN 0021-9525, 6/2008, Volume 181, Issue 7, pp. 1129 - 1139
Reactive oxygen species (ROS) function as intracellular signaling molecules in a diverse range of biological processes. However, it is unclear how freely... 
COS cells | Oxidases | Reactive oxygen species | Phosphorylation | Receptors | Smooth muscle myocytes | Antibodies | Oxidation | Physiological regulation | Endothelial cells | GROWTH-FACTOR RECEPTOR | NAD(P)H OXIDASE | OXIDATIVE STRESS | TYROSINE-PHOSPHATASE 1B | NITRIC-OXIDE SYNTHASE | ENDOTHELIAL-CELLS | SMOOTH-MUSCLE-CELLS | ENDOPLASMIC-RETICULUM | HYDROGEN-PEROXIDE | KINASE ACTIVATION | CELL BIOLOGY | Endoplasmic Reticulum - enzymology | Reactive Oxygen Species - metabolism | Humans | NADPH Oxidases - metabolism | Cercopithecus aethiops | Protein Transport - drug effects | Antioxidants - pharmacology | NADPH Oxidase 4 | Mutation - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Receptor, Epidermal Growth Factor - metabolism | Animals | Substrate Specificity - drug effects | Signal Transduction - drug effects | Endothelial Cells - cytology | Endoplasmic Reticulum - drug effects | Oxidation-Reduction - drug effects | Cell Proliferation - drug effects | Mice | Epidermal Growth Factor - pharmacology | Phosphorylation - drug effects | COS Cells | Endothelial Cells - enzymology | Endothelial Cells - drug effects | Evaluation | Vascular endothelium | Cell research | Cellular signal transduction | Properties | Endoplasmic reticulum | Antioxidants | Signal transduction | Enzymes | Oxygen | Biochemistry | Cells | Index Medicus | s
Journal Article
Nature, ISSN 0028-0836, 06/2017, Volume 546, Issue 7658, pp. 431 - 435
Therapies that target signalling molecules that are mutated in cancers can often have substantial short-term effects, but the emergence of resistant cancer... 
METASTATIC MELANOMA | BRAF INHIBITOR | SUBPOPULATIONS | CHROMATIN | MULTIDISCIPLINARY SCIENCES | SINGLE MAMMALIAN-CELLS | STATE | MECHANISMS | MUTATIONS | VEMURAFENIB | PLASTICITY | Transcription, Genetic - drug effects | Humans | Male | Transcription Factor AP-1 - metabolism | DNA-Binding Proteins - metabolism | Melanoma - genetics | Female | Indoles - pharmacology | Epigenesis, Genetic - drug effects | Gene Expression Regulation, Neoplastic - drug effects | SOXE Transcription Factors - deficiency | Single-Cell Analysis | Cellular Reprogramming - genetics | ErbB Receptors - metabolism | In Situ Hybridization, Fluorescence | Nuclear Proteins - metabolism | Signal Transduction - genetics | Melanoma - pathology | Sulfonamides - pharmacology | Cellular Reprogramming - drug effects | Transcription Factors - metabolism | Xenograft Model Antitumor Assays | Genetic Markers - drug effects | Vemurafenib | Drug Resistance, Neoplasm - genetics | Animals | Signal Transduction - drug effects | Genetic Markers - genetics | Cell Line, Tumor | Oncogene Protein p65(gag-jun) - metabolism | Drug Resistance, Neoplasm - drug effects | SOXE Transcription Factors - genetics | Antimitotic agents | Cell interaction | Dosage and administration | Antineoplastic agents | Drug resistance | Observations | Health aspects | Subpopulations | Transcription factors | Substance abuse treatment | Variability | Activator protein 1 | Melanoma | Genomes | Kinases | Gene expression | Sox10 protein | Signal transduction | Signaling | Converting | Population | Mutation | Differentiation | Deoxyribonucleic acid--DNA | Cancer | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 500, Issue 7463, pp. 422 - 426
Journal Article
Nature, ISSN 0028-0836, 12/2012, Volume 492, Issue 7429, pp. 433 - 437
Journal Article
Developmental Cell, ISSN 1534-5807, 2007, Volume 13, Issue 2, pp. 177 - 189
Journal Article
Clinical Immunology, ISSN 1521-6616, 2010, Volume 137, Issue 1, pp. 89 - 101
Abstract Activated macrophages have been characterized as M1 and M2 according to their inflammatory response pattern. Here we analyzed the M2 marker expression... 
Allergy and Immunology | M2 phenotype | Th2 cytokines | Pulmonary fibrosis | IL-1RA | CCL22 | Sarcoidosis | JAK/STAT pathway | CCL18 | Alveolar macrophages | CCL17 | INTERLEUKIN-1 RECEPTOR ANTAGONIST | CYTOKINE | IMMUNOLOGY | SYSTEMIC-SCLEROSIS | STAT3 ACTIVATION | INTERSTITIAL LUNG-DISEASES | MANNOSE RECEPTOR | GENE-EXPRESSION | TNF-ALPHA RELEASE | GROWTH-FACTOR | UP-REGULATION | Mannose-Binding Lectins - metabolism | Tumor Necrosis Factor-alpha - metabolism | Gene Expression - drug effects | Humans | Middle Aged | STAT Transcription Factors - metabolism | Interleukin 1 Receptor Antagonist Protein - genetics | Male | Monocytes - metabolism | Monocytes - immunology | Sarcoidosis, Pulmonary - diagnosis | Idiopathic Pulmonary Fibrosis - metabolism | Young Adult | Lectins, C-Type - metabolism | Signal Transduction - immunology | Interleukin-4 - pharmacology | Interleukin 1 Receptor Antagonist Protein - metabolism | Scleroderma, Systemic - complications | Aged, 80 and over | Adult | Female | Bronchoalveolar Lavage Fluid - cytology | Pulmonary Fibrosis - metabolism | Interleukin-8 - metabolism | Macrophages, Alveolar - immunology | Pulmonary Fibrosis - etiology | Sarcoidosis, Pulmonary - complications | Cytokines - metabolism | Macrophage Activation - immunology | Scleroderma, Systemic - metabolism | Pulmonary Fibrosis - immunology | Receptors, Cell Surface - metabolism | Idiopathic Pulmonary Fibrosis - immunology | Monocytes - drug effects | Signal Transduction - drug effects | Macrophages, Alveolar - drug effects | Sarcoidosis, Pulmonary - metabolism | Chemokines, CC - genetics | Aged | Macrophages, Alveolar - metabolism | Macrophage Activation - drug effects | Interleukin-10 - pharmacology | Chemokines, CC - metabolism | Respiratory tract diseases | Systemic scleroderma | Transforming growth factors | Macrophages | Scleroderma (Disease) | Index Medicus | Alveoli
Journal Article
The Plant Cell, ISSN 1040-4651, 3/2007, Volume 19, Issue 3, pp. 805 - 818
Journal Article
Neuron, ISSN 0896-6273, 04/2014, Volume 82, Issue 2, pp. 380 - 397
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2013, Volume 8, Issue 11, pp. e80883 - e80883
Background: Kaempferol has been proposed as a potential drug for cancer chemoprevention and treatment because it is a natural polyphenol contained in... 
MIGRATION | INACTIVATION | INVASION | COLORECTAL-CANCER | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | TISSUE INHIBITOR | FLAVONOIDS | PROGNOSTIC-SIGNIFICANCE | NF-KAPPA-B | CARCINOMA | Transcription, Genetic - drug effects | Protein Binding - genetics | Nitriles - pharmacology | DNA, Neoplasm - metabolism | Humans | Cell Survival - genetics | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA, Messenger - metabolism | Transcription Factor AP-1 - metabolism | Cell Movement - genetics | Tissue Inhibitor of Metalloproteinase-2 - metabolism | Protein Binding - drug effects | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Mouth Neoplasms - enzymology | Cell Survival - drug effects | Butadienes - pharmacology | Matrix Metalloproteinase 2 - metabolism | Neoplasm Invasiveness | RNA, Messenger - genetics | Signal Transduction - genetics | Down-Regulation - drug effects | Cell Movement - drug effects | Matrix Metalloproteinase 2 - genetics | Matrix Metalloproteinase Inhibitors - pharmacology | Signal Transduction - drug effects | Cell Line, Tumor | Mouth Neoplasms - pathology | Kaempferols - pharmacology | Prevention | Medical research | Care and treatment | Squamous cell carcinoma | RNA | Analysis | Medicine, Experimental | Metastasis | Cardiovascular diseases | Mouth cancer | Cancer | Biotechnology | Food plants | Transcription factors | Tongue | Phosphorylation | Transcription | Oral cancer | Laboratories | Gene regulation | Colorectal cancer | Otolaryngology | Biochemistry | Matrix metalloproteinase | Tissue inhibitor of metalloproteinase 2 | Cancer therapies | Metastases | Angiogenesis | Signal transduction | Cell cycle | Physiology | Metalloproteinase | Food | Kaempferol | Activator protein 1 | Melanoma | Extracellular signal-regulated kinase | c-Jun protein | Plant protection | Breast cancer | Gene expression | Gelatinase A | Studies | Signaling | Bone cancer | Chemotherapy | Flavonoids | Hospitals | Molecular modelling | Cell migration | Apoptosis | Index Medicus
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2013, Volume 210, Issue 9, pp. 1695 - 1710
Treatment with monoclonal antibody specific for cytotoxic T lymphocyte-associated antigen 4 (CTLA-4), an inhibitory receptor expressed by T lymphocytes, has... 
EFFECTOR | MEDICINE, RESEARCH & EXPERIMENTAL | CTLA-4 BLOCKADE | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | CANCER-PATIENTS | IN-VIVO | COMBINATION IMMUNOTHERAPY | MONOCLONAL-ANTIBODY | IMMUNOLOGY | LARGE ESTABLISHED MELANOMA | GAMMA-RIV | ANTITUMOR-ACTIVITY | Fas Ligand Protein - metabolism | Lymph Nodes - pathology | Antibodies, Blocking - pharmacology | Lymphocyte Depletion | Granulocyte-Macrophage Colony-Stimulating Factor - therapeutic use | Receptors, IgG - metabolism | T-Lymphocytes, Regulatory - immunology | Signal Transduction - immunology | Melanoma - prevention & control | Lymph Nodes - drug effects | Cell Membrane - metabolism | Clone Cells | Cell Membrane - drug effects | Tumor Microenvironment - drug effects | Phagocytes - drug effects | Mice, Inbred C57BL | Treatment Outcome | Lymph Nodes - immunology | Lymphocytes, Tumor-Infiltrating - drug effects | Melanoma - pathology | Phagocytes - immunology | TNF-Related Apoptosis-Inducing Ligand - metabolism | Tumor Microenvironment - immunology | T-Lymphocytes, Regulatory - drug effects | Animals | Lymphocytes, Tumor-Infiltrating - pathology | Signal Transduction - drug effects | Melanoma - immunology | CD8-Positive T-Lymphocytes - drug effects | Antibodies, Blocking - therapeutic use | Lymphocyte Count | Mice | CD11b Antigen - metabolism | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Melanoma - therapy | CD4 Antigens - metabolism | Lymphocytes, Tumor-Infiltrating - immunology | Index Medicus
Journal Article