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Chemical Society reviews, ISSN 0306-0012, 03/2016, Volume 45, Issue 6, pp. 1738 - 1749
Developing simple and inexpensive methods to ultrasensitively detect biomarkers is important for medical diagnosis, food analysis and environmental security.... 
Biosensing Techniques | Nanostructures
Journal Article
Science, ISSN 0036-8075, 5/2007, Volume 316, Issue 5827, pp. 1039 - 1043
The epidermal growth factor receptor (EGFR) kinase inhibitors gefitinib and erlotinib are effective treatments for lung cancers with EGFR activating mutations,... 
Tumor cell line | Phosphorylation | Cell lines | Antibodies | Reports | CHO cells | Genetic mutation | Signal amplification | Cell extracts | Tumors | Lung neoplasms | THERAPY | GROWTH-FACTOR-RECEPTOR | GENE | TYROSINE KINASE | ADENOCARCINOMA | MULTIDISCIPLINARY SCIENCES | ACQUIRED-RESISTANCE | MUTATIONS | INHIBITOR | GASTROINTESTINAL STROMAL TUMORS | IMATINIB MESYLATE | Lung Neoplasms - drug therapy | Enzyme Inhibitors | Receptor, ErbB-3 - metabolism | Cricetulus | Humans | Lung Neoplasms - metabolism | Drug Resistance, Neoplasm | Lung Neoplasms - pathology | Antineoplastic Agents - therapeutic use | Phosphatidylinositol 3-Kinases - metabolism | Sulfones - pharmacology | Receptors, Growth Factor - genetics | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | CHO Cells | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Proto-Oncogene Proteins - metabolism | Cricetinae | Signal Transduction | Carcinoma, Non-Small-Cell Lung - genetics | Proto-Oncogene Proteins c-met | Carcinoma, Non-Small-Cell Lung - metabolism | Proto-Oncogene Proteins - genetics | Animals | Gene Amplification | Quinazolines - therapeutic use | Cell Line, Tumor | Cell Proliferation - drug effects | Carcinoma, Non-Small-Cell Lung - drug therapy | Quinazolines - pharmacology | Receptors, Growth Factor - metabolism | Gene amplification | Gene mutations | Lung cancer | Physiological aspects | Genetic aspects | Chemical properties | Drug resistance | Gefitinib | Drug therapy | Health aspects | Oncology | Inhibitor drugs
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 10/2019, Volume 58, Issue 42, pp. 14877 - 14881
Precise control over signal amplification provides unparalleled opportunities for diverse applications. However, spatiotemporally controlled amplification has... 
hybridization chain reaction | RNA | fluorescence | signal amplification | bioimaging | Fluorescence | Remote control | Messenger RNA | Amplification | Upconversion | Infrared radiation | mRNA | Hybridization | Photochemistry
Journal Article
Journal Article
Analytical Chemistry, ISSN 0003-2700, 08/2013, Volume 85, Issue 16, pp. 7689 - 7695
Journal Article
Analyst (Cambridge UK), ISSN 0003-2654, 05/2016, Volume 141, Issue 11, pp. 3157 - 3218
Diagnostic assays that rely on molecular interactions have come a long way; from initial reversible detection systems towards irreversible reaction... 
Amplification | Categories | Molecular interactions | Instrumentation | Strategy | Diagnostic systems | Assaying | Detection
Journal Article
Analyst, ISSN 0003-2654, 5/2016, Volume 141, Issue 11, pp. 3157 - 3218
Journal Article
Physical Review A - Atomic, Molecular, and Optical Physics, ISSN 1050-2947, 07/2010, Volume 82, Issue 1
We describe a phase-amplification technique using a Sagnac interferometer. We monitor the relative phase between two paths of a precisely misaligned... 
LIMIT | PHYSICS, ATOMIC, MOLECULAR & CHEMICAL | OPTICS | Physics - Quantum Physics | PHASE SHIFT | AMPLIFICATION | INTERFEROMETERS | CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS | MEASURING INSTRUMENTS | SENSITIVITY | SIGNALS | INTERFEROMETRY | DETECTION
Journal Article
Nature Communications, ISSN 2041-1723, 12/2019, Volume 10, Issue 1, pp. 1 - 22
Acquired resistance to MEK1/2 inhibitors (MEKi) arises through amplification of BRAFV600E or KRASG13D to reinstate ERK1/2 signalling. Here we show that... 
Cell proliferation | Amplification | Signaling | Senescence | Cell survival | Mesenchyme | Cell death | Withdrawal | Chemoresistance | Cell cycle | Extracellular signal-regulated kinase | Tumors
Journal Article
Accounts of Chemical Research, ISSN 0001-4842, 04/2017, Volume 50, Issue 4, pp. 1059 - 1068
MicroRNAs (miRNAs) are a class of small noncoding RNAs that act as pivotal post-transcriptional regulators of gene expression, thus involving in many... 
PADLOCK PROBES | ROLLING-CIRCLE AMPLIFICATION | QUANTIFICATION | IN-SITU HYBRIDIZATION | ULTRASENSITIVE DETECTION | MIRNA DETECTION | CANCER | EXPRESSION | CHEMISTRY, MULTIDISCIPLINARY | SIGNAL AMPLIFICATION | NUCLEIC-ACIDS | Temperature | MicroRNAs - analysis | Humans | MicroRNAs - metabolism | MicroRNAs - genetics | In Vitro Techniques | Single-Cell Analysis
Journal Article
Sensors & Actuators: B. Chemical, ISSN 0925-4005, 2010, Volume 149, Issue 1, pp. 325 - 328
Journal Article