X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Patent (1107991) 1107991
Journal Article (306288) 306288
Publication (41580) 41580
Book Review (40634) 40634
Book Chapter (5605) 5605
Conference Proceeding (5043) 5043
Dissertation (1540) 1540
Magazine Article (1146) 1146
Book / eBook (715) 715
Government Document (594) 594
Trade Publication Article (541) 541
Newspaper Article (480) 480
Web Resource (262) 262
Reference (141) 141
Newsletter (110) 110
Data Set (68) 68
Streaming Video (63) 63
Archival Material (46) 46
Paper (46) 46
Standard (26) 26
Microfilm (7) 7
Presentation (6) 6
Electronic Resource (5) 5
Journal / eJournal (5) 5
Transcript (2) 2
Art (1) 1
Painting (1) 1
Report (1) 1
Technical Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
physics (949554) 949554
signalling (919283) 919283
alarm systems (455026) 455026
order telegraphs (454989) 454989
signalling or calling systems (454989) 454989
transporting (352284) 352284
performing operations (352280) 352280
electricity (327070) 327070
traffic control systems (307119) 307119
vehicles in general (301553) 301553
testing (258049) 258049
measuring (257772) 257772
electric communication technique (244976) 244976
index medicus (241894) 241894
arrangement of signalling or lighting devices, the mounting orsupporting thereof or circuits therefor, for vehicles ingeneral (212256) 212256
computing (187212) 187212
counting (187206) 187206
calculating (187200) 187200
transmission systems for measured values, control or similarsignals (180159) 180159
animals (147232) 147232
humans (137653) 137653
navigation (95163) 95163
surveying (95055) 95055
gyroscopic instruments (95038) 95038
measuring distances, levels or bearings (95038) 95038
photogrammetry or videogrammetry (95038) 95038
mechanical engineering (91180) 91180
lighting (91105) 91105
heating (91070) 91070
weapons (91064) 91064
blasting (91047) 91047
vehicles, vehicle fittings, or vehicle parts, not otherwiseprovided for (89662) 89662
electric digital data processing (83710) 83710
pictorial communication, e.g. television (75532) 75532
mice (70848) 70848
human necessities (68735) 68735
signal transduction (67581) 67581
wireless communications networks (66020) 66020
education (65534) 65534
advertising (64945) 64945
cryptography (64909) 64909
display (64897) 64897
seals (64862) 64862
transmission of digital information, e.g. telegraphiccommunication (61839) 61839
handling record carriers (59894) 59894
presentation of data (59894) 59894
recognition of data (59894) 59894
record carriers (59894) 59894
radio navigation (59518) 59518
analogous arrangements using other waves (59516) 59516
determining distance or velocity by use of radio waves (59516) 59516
locating or presence-detecting by use of the reflection orreradiation of radio waves (59516) 59516
radio direction-finding (59516) 59516
cell biology (59289) 59289
general tagging of cross-sectional technologies spanning over several sections of the ipc (58629) 58629
general tagging of new technological developments (58629) 58629
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (58629) 58629
regulating (55474) 55474
controlling (55472) 55472
biochemistry & molecular biology (54209) 54209
data processing systems or methods, specially adapted foradministrative, commercial, financial, managerial, supervisoryor forecasting purposes (53557) 53557
systems or methods specially adapted for administrative,commercial, financial, managerial, supervisory or forecastingpurposes, not otherwise provided for (53557) 53557
transmission (52381) 52381
male (50608) 50608
proteins (48392) 48392
signaling (46758) 46758
checking-devices (45043) 45043
telephonic communication (44608) 44608
basic electric elements (44148) 44148
conjoint control of vehicle sub-units of different type ordifferent function (44093) 44093
control systems specially adapted for hybrid vehicles (44093) 44093
road vehicle drive control systems for purposes not related tothe control of a particular sub-unit (44093) 44093
female (43888) 43888
non-portable lighting devices (43716) 43716
systems thereof (43716) 43716
vehicle lighting devices specially adapted for vehicleexteriors (43716) 43716
expression (42135) 42135
fixed constructions (42043) 42043
functional features or details of lighting devices or systemsthereof (39711) 39711
structural combinations of lighting devices with otherarticles, not otherwise provided for (39711) 39711
selecting (39198) 39198
models (39003) 39003
phosphorylation (38885) 38885
apoptosis (37512) 37512
gene expression (37062) 37062
activation (36820) 36820
maps (36783) 36783
diagrams (36610) 36610
appliances for teaching, or communicating with, the blind,deaf or mute (36605) 36605
educational or demonstration appliances (36605) 36605
globes (36605) 36605
planetaria (36605) 36605
technologies or applications for mitigation or adaptation againstclimate change (34549) 34549
hygiene (33919) 33919
medical or veterinary science (33865) 33865
image data processing or generation, in general (33687) 33687
rats (32844) 32844
identification (32444) 32444
electric techniques not otherwise provided for (30997) 30997
cancer (30813) 30813
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (270) 270
Gerstein Science - Stacks (81) 81
UTL at Downsview - May be requested (47) 47
Robarts - Stacks (46) 46
Engineering & Comp. Sci. - Stacks (44) 44
Collection Dvlpm't (Acquisitions) - Vendor file (33) 33
UofT at Mississauga - Stacks (22) 22
Collection Dvlpm't (Acquisitions) - Closed Orders (12) 12
Media Commons - Microtexts (11) 11
UofT at Scarborough - Stacks (7) 7
Robarts - Government Pubs (4) 4
Earth Sciences (Noranda) - Stacks (3) 3
East Asian (Cheng Yu Tung) - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Thomas Fisher Rare Book - Rare Book (3) 3
Trinity College (John W Graham) - Stacks (3) 3
Chemistry (A D Allen) - Stacks (2) 2
Mathematical Sciences - Stacks (2) 2
Music - Stacks (2) 2
Victoria University E.J. Pratt - Stacks (2) 2
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Art - Library use only (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
Engineering & Comp. Sci. - May be requested in 6-10 wks (1) 1
Engineering & Comp. Sci. - Periodical Stacks (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Engineering & Comp. Sci. - Special Collections (1) 1
Faculty of Information - Juvenile (1) 1
Law (Bora Laskin) - Stacks (1) 1
Law (Bora Laskin) - Theses (1) 1
Massey College (Robertson Davies) - Rare Book (1) 1
OISE - Children's Literature (1) 1
OISE - Stacks (1) 1
Robarts - Gov Pub Storage: Request at Reference Desk 4th floor (1) 1
Robarts - Not Returned (1) 1
Royal Ontario Museum - Stacks (1) 1
UofT Schools - Special Collections (1) 1
Victoria University CRRS - Library use only (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1344215) 1344215
Chinese (222320) 222320
French (130162) 130162
German (78754) 78754
Korean (57645) 57645
Japanese (54709) 54709
Russian (12465) 12465
Finnish (2601) 2601
Spanish (2133) 2133
Swedish (2129) 2129
Polish (1540) 1540
Czech (1210) 1210
Italian (1055) 1055
Norwegian (1024) 1024
Ukrainian (655) 655
Dutch (593) 593
Portuguese (583) 583
Danish (432) 432
Hungarian (380) 380
Slovenian (315) 315
Greek (265) 265
Hebrew (231) 231
Slovak (217) 217
Bulgarian (146) 146
Croatian (141) 141
Romanian (129) 129
Serbian (71) 71
Lithuanian (63) 63
Estonian (57) 57
Indonesian (52) 52
Latvian (41) 41
Turkish (39) 39
Arabic (15) 15
Icelandic (8) 8
Moldavian (8) 8
Persian (6) 6
Bosnian (5) 5
Catalan (2) 2
Amharic (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Metabolism, ISSN 1550-4131, 2006, Volume 3, Issue 5, pp. 343 - 353
Although the class I phosphoinositide 3-kinase (PI3K) pathway is central to the metabolic actions of insulin, its mechanism of action is not well understood.... 
SIGNALING
Journal Article
Science Signaling, ISSN 1945-0877, 01/2018, Volume 11, Issue 513, p. eaas9779
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, pp. e47936 - e47936
Glucagon-like peptide-1 (GLP-1) released from intestinal L cells in response to nutrients has many physiological effects but particularly enhances... 
PATHWAYS | CELLS | ACTIVATION | HEALTHY-SUBJECTS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DEGRADATION | SMALL-MOLECULE AGONISTS | SECRETION | GASTRIC-INHIBITORY POLYPEPTIDE | TYPE-2 DIABETES-MELLITUS | Receptors, Glucagon - antagonists & inhibitors | Calcium - metabolism | Allosteric Regulation | Humans | Peptide Fragments - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Sulfones - pharmacology | Extracellular Signal-Regulated MAP Kinases - genetics | Quinoxalines - pharmacology | Peptides - metabolism | Transfection | Biotransformation | Adenosine Monophosphate - biosynthesis | Receptors, Glucagon - agonists | Cell Line | Gene Expression | Peptide Fragments - metabolism | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 1 - analogs & derivatives | Glucagon-Like Peptide 1 - pharmacology | Rats | Receptors, Glucagon - metabolism | Peptides - pharmacology | Insulin - metabolism | Animals | Glucagon-Like Peptide-1 Receptor | Calcium Signaling - drug effects | Type 2 diabetes | Care and treatment | Glucagon | Metabolites | Physiological aspects | Research | Risk factors | Physiological effects | Peptides | Insulinoma | Systematic review | Hormones | Glucose | Peptide hormones | Calcium signalling | Proteins | Allosteric properties | Intestine | Penicillin | Nutrients | Physiology | Glucagon-like peptide 1 | Recombinant | Peptidase | AMP | Diabetes mellitus | Extracellular signal-regulated kinase | Pharmacology | L cells | Insulin | Affinity | Ligands | Diabetes | Calcium (extracellular) | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36800 - e36800
The dysregulation of receptor protein tyrosine kinase (RPTK) function can result in changes in cell proliferation, cell growth and metastasis leading to... 
TYROSINE KINASE TYRO3 | APOPTOTIC CELLS | PI3 KINASE | BIOLOGY | SURVIVAL ACTIVITIES | FAMILY RECEPTORS | SMOOTH-MUSCLE-CELLS | TAM RECEPTORS | GROWTH-FACTOR | PROTEIN-S | ARREST-SPECIFIC GENE | Proto-Oncogene Proteins - metabolism | Cell Line | Up-Regulation | Phosphorylation | Cell Proliferation | Signal Transduction | Intercellular Signaling Peptides and Proteins - genetics | Rats | Proto-Oncogene Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | MAP Kinase Signaling System | Intercellular Signaling Peptides and Proteins - metabolism | Animals | Transfection | Receptor Protein-Tyrosine Kinases - genetics | c-Mer Tyrosine Kinase | Tyrosine | Protein kinases | Mitogens | Analysis | Cell proliferation | Transformation | Immunoprecipitation | Kinases | Metastases | Axl protein | Skin cancer | Proteins | Signal transduction | Receptors | Cell activation | Cell growth | Rodents | Fibroblasts | Protein-tyrosine kinase receptors | Growth factors | Protein-tyrosine kinase | Immunoglobulins | Immune response | Melanoma | Extracellular signal-regulated kinase | MAP kinase | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Studies | Signaling | Molecular modelling | Inhibitors | Mutagenesis | Transformations (mathematics) | Receptor mechanisms | Tumors | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 4, pp. e0154638 - e0154638
[This corrects the article DOI: 10.1371/journal.pone.0147830.]. 
Signaling
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, pp. e21549 - e21549
Background: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense... 
TUMOR PH | ACTIVATED PROTEIN-KINASE | CARDIAC-ARREST | CYTOPLASMIC PH | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR PH | PHOSPHATIDIC-ACID | TUBEROUS SCLEROSIS | CELL-GROWTH | EXTRACELLULAR PH | HUMAN CANCER | Phosphorylation - physiology | Cell Line | Tumor Suppressor Proteins - metabolism | Humans | Multiprotein Complexes | Signal Transduction - genetics | Mechanistic Target of Rapamycin Complex 1 | Proteins - genetics | Phosphorylation - genetics | Animals | Proteins - metabolism | Tumor Suppressor Proteins - genetics | Cell Line, Tumor | Signal Transduction - physiology | TOR Serine-Threonine Kinases | Hydrogen-Ion Concentration | Tuberous sclerosis | Protein biosynthesis | Hydrogen-ion concentration | Protein kinases | Tuberous sclerosis 2 protein | Drugs | Cell culture | Phosphorylation | Brain cancer | Acidification | Raf protein | AKT protein | Cytotoxicity | Hamartin | Biosynthesis | Biochemistry | Kinases | pH effects | TSC1 protein | Autophagy | Sclerosis | Proteins | Breast carcinoma | Signal transduction | Pathways | Energy | Hydrogen ions | Immunotherapy | Fibroblasts | Physiology | Inhibition | Vascular endothelial growth factor | Starvation | Extracellular signal-regulated kinase | Energy expenditure | Substrate inhibition | Embryo fibroblasts | Metabolism | TSC2 protein | Signaling | Acids | Perfusion | Protein synthesis | Protein kinase | Signal processing | Hypoxia | Molecular biology | Biosensors | Cytoplasm | Tumors | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, pp. e16781 - e16781
Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and posses antitumor activity. Here, we examined... 
CYCLIN-DEPENDENT KINASES | SIGNALING PATHWAYS | INHIBITION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAP KINASES | DEATH | STRESS | TRANSIENT | ESTROGEN-RECEPTOR | Endometrial Neoplasms - enzymology | Apoptosis - drug effects | Humans | Enzyme Activation - drug effects | Flavonoids - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Caspases - biosynthesis | Cell Line, Tumor | Enzyme Induction - drug effects | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Female | Cell Proliferation - drug effects | Flavonoids - pharmacology | Cell Cycle - drug effects | Flavonoids - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cytochrome c | Endometrial cancer | Health aspects | Estrogen | Cancer | Apoptosis | Cell proliferation | Cytochrome | Phosphorylation | Bax protein | Bcl-2 protein | Estrogens | Estrogen receptors | Activation | Kinases | ADP | MAP kinase kinase | Anticancer properties | Cell activation | Cell growth | Antitumor agents | Ribose | Inhibition | Pretreatment | Endometrium | Cyclin-dependent kinases | Extracellular signal-regulated kinase | Caspase | Poly(ADP-ribose) polymerase | MAP kinase | Polymerase | Inhibitors | Cyclin-dependent kinase inhibitor p27 | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, pp. e35826 - e35826
Receptor tyrosine kinase signaling cooperates with WNT/beta-catenin signaling in regulating many biological processes, but the mechanisms of their interaction... 
INSULIN | MECHANISM | BIOLOGY | DYSPLASIA | MUTATIONS | WNT | FGFR3 | CANCER | LRP6 | Phosphorylation | Humans | Gene Expression Regulation | Phosphatidylinositol 3-Kinases - metabolism | Glycogen Synthase Kinase 3 - metabolism | Wnt Proteins - metabolism | Receptor Protein-Tyrosine Kinases | beta Catenin - metabolism | Proto-Oncogene Proteins c-akt - genetics | beta Catenin - genetics | Phosphatidylinositol 3-Kinases - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Glycogen Synthase Kinase 3 - genetics | Wnt Signaling Pathway - genetics | HEK293 Cells | Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Mitogen-Activated Protein Kinases - metabolism | Wnt protein | AKT protein | Biology | Kinases | Throat cancer | Proteins | Signal transduction | β-catenin | Immunology | TrkA protein | Protein-tyrosine kinase receptors | Physiology | Standard deviation | Protein-tyrosine kinase | Fibroblast growth factor receptor 2 | Tyrosine | Epidermal growth factor receptors | Extracellular signal-regulated kinase | MAP kinase | Biophysics | Cadherin | Biological activity | 1-Phosphatidylinositol 3-kinase | Golgi apparatus | Medicine | Signaling | Low density lipoprotein receptors | Mutation | Prostate cancer | Fibroblast growth factor receptors | Tumors | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e62705 - e62705
Background: A-kinase anchoring proteins (AKAPs) are scaffolding molecules that coordinate and integrate G-protein signaling events to regulate development,... 
PROTEIN-KINASE-A | BREAST-CANCER | CELL INVASIVENESS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | MOUSE | EXCHANGE FACTOR AKAP13 | RECEPTOR | INDUCED CARDIOMYOCYTE HYPERTROPHY | ANCHORING PROTEIN | SIGNALING COMPLEX | Embryo, Mammalian | Minor Histocompatibility Antigens | Heart - embryology | Myocardial Contraction - drug effects | Male | A Kinase Anchor Proteins - genetics | Gene Expression Regulation, Developmental | Guanine Nucleotide Exchange Factors - metabolism | Electrocardiography | Female | A Kinase Anchor Proteins - metabolism | Heart - physiopathology | Protein Structure, Tertiary | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Breeding | Cardiomegaly - physiopathology | Organ Size | Stroke Volume - drug effects | Mice, Transgenic | Animals | Cardiomegaly - chemically induced | Heart - drug effects | Mice | Isoproterenol - adverse effects | Cardiomegaly - metabolism | Heart | Protein kinase A | Cell culture | Cardiovascular disease | Isoproterenol | Kinases | Guanine | Defects | Eutrophication | Proteins | Embryogenesis | Fertility | Rodents | Physiology | Guanine nucleotide exchange factor | Heart diseases | Anchoring | Pharmaceutical sciences | Heart failure | Contractility | Cardiomyocytes | Pharmacology | Breast cancer | Embryos | Muscle contraction | Signaling | Scaffolding | Isoforms | Mutation | Alzheimers disease | Viability | Binding sites | Hypertrophy | Ejection | Index Medicus
Journal Article