X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Patent (1107144) 1107144
Journal Article (308173) 308173
Publication (49128) 49128
Book Chapter (5460) 5460
Conference Proceeding (4998) 4998
Book Review (2749) 2749
Dissertation (1540) 1540
Magazine Article (1053) 1053
Book / eBook (728) 728
Government Document (592) 592
Trade Publication Article (524) 524
Newspaper Article (472) 472
Web Resource (256) 256
Reference (141) 141
Newsletter (109) 109
Data Set (97) 97
Streaming Video (63) 63
Archival Material (46) 46
Paper (45) 45
Standard (26) 26
Microfilm (7) 7
Presentation (6) 6
Electronic Resource (5) 5
Journal / eJournal (3) 3
Transcript (2) 2
Art (1) 1
Painting (1) 1
Report (1) 1
Technical Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
physics (948847) 948847
signalling (918604) 918604
alarm systems (454664) 454664
order telegraphs (454627) 454627
signalling or calling systems (454627) 454627
transporting (352014) 352014
performing operations (352010) 352010
electricity (326814) 326814
traffic control systems (306869) 306869
vehicles in general (301324) 301324
testing (257848) 257848
measuring (257569) 257569
electric communication technique (244779) 244779
arrangement of signalling or lighting devices, the mounting orsupporting thereof or circuits therefor, for vehicles ingeneral (212097) 212097
computing (187058) 187058
counting (187052) 187052
calculating (187046) 187046
transmission systems for measured values, control or similarsignals (180036) 180036
index medicus (158433) 158433
animals (146807) 146807
humans (136999) 136999
navigation (95078) 95078
surveying (94970) 94970
gyroscopic instruments (94953) 94953
measuring distances, levels or bearings (94953) 94953
photogrammetry or videogrammetry (94953) 94953
mechanical engineering (91100) 91100
lighting (91022) 91022
heating (90988) 90988
weapons (90981) 90981
blasting (90964) 90964
vehicles, vehicle fittings, or vehicle parts, not otherwiseprovided for (89592) 89592
electric digital data processing (83649) 83649
pictorial communication, e.g. television (75485) 75485
mice (70711) 70711
human necessities (68687) 68687
signal transduction (67998) 67998
wireless communications networks (65961) 65961
education (65477) 65477
advertising (64879) 64879
cryptography (64854) 64854
display (64840) 64840
seals (64805) 64805
transmission of digital information, e.g. telegraphiccommunication (61781) 61781
handling record carriers (59854) 59854
presentation of data (59854) 59854
recognition of data (59854) 59854
record carriers (59854) 59854
cell biology (59548) 59548
radio navigation (59478) 59478
analogous arrangements using other waves (59476) 59476
determining distance or velocity by use of radio waves (59476) 59476
locating or presence-detecting by use of the reflection orreradiation of radio waves (59476) 59476
radio direction-finding (59476) 59476
general tagging of cross-sectional technologies spanning over several sections of the ipc (58598) 58598
general tagging of new technological developments (58598) 58598
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (58598) 58598
regulating (55439) 55439
controlling (55438) 55438
biochemistry & molecular biology (53957) 53957
data processing systems or methods, specially adapted foradministrative, commercial, financial, managerial, supervisoryor forecasting purposes (53503) 53503
systems or methods specially adapted for administrative,commercial, financial, managerial, supervisory or forecastingpurposes, not otherwise provided for (53503) 53503
transmission (52344) 52344
male (50335) 50335
proteins (48900) 48900
signaling (47128) 47128
checking-devices (45006) 45006
telephonic communication (44568) 44568
basic electric elements (44119) 44119
conjoint control of vehicle sub-units of different type ordifferent function (44070) 44070
control systems specially adapted for hybrid vehicles (44070) 44070
road vehicle drive control systems for purposes not related tothe control of a particular sub-unit (44070) 44070
non-portable lighting devices (43680) 43680
systems thereof (43680) 43680
vehicle lighting devices specially adapted for vehicleexteriors (43680) 43680
female (43624) 43624
expression (42493) 42493
fixed constructions (42015) 42015
functional features or details of lighting devices or systemsthereof (39682) 39682
structural combinations of lighting devices with otherarticles, not otherwise provided for (39682) 39682
phosphorylation (39183) 39183
selecting (39165) 39165
models (38947) 38947
apoptosis (37695) 37695
gene expression (37405) 37405
activation (37145) 37145
maps (36748) 36748
diagrams (36573) 36573
appliances for teaching, or communicating with, the blind,deaf or mute (36568) 36568
educational or demonstration appliances (36568) 36568
globes (36568) 36568
planetaria (36568) 36568
technologies or applications for mitigation or adaptation againstclimate change (34525) 34525
hygiene (33900) 33900
medical or veterinary science (33844) 33844
image data processing or generation, in general (33663) 33663
rats (32826) 32826
identification (32491) 32491
electric techniques not otherwise provided for (30981) 30981
cancer (30861) 30861
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (264) 264
Gerstein Science - Stacks (80) 80
Robarts - Stacks (46) 46
UTL at Downsview - May be requested (45) 45
Engineering & Comp. Sci. - Stacks (44) 44
Collection Dvlpm't (Acquisitions) - Vendor file (33) 33
UofT at Mississauga - Stacks (21) 21
Collection Dvlpm't (Acquisitions) - Closed Orders (14) 14
Media Commons - Microtexts (11) 11
UofT at Scarborough - Stacks (7) 7
Robarts - Government Pubs (4) 4
Earth Sciences (Noranda) - Stacks (3) 3
East Asian (Cheng Yu Tung) - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Thomas Fisher Rare Book - Rare Book (3) 3
Trinity College (John W Graham) - Stacks (3) 3
Engineering & Comp. Sci. - May be requested in 6-10 wks (2) 2
Mathematical Sciences - Stacks (2) 2
Music - Stacks (2) 2
Victoria University E.J. Pratt - Stacks (2) 2
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Art - Library use only (1) 1
Chemistry (A D Allen) - Stacks (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
East Asian (Cheng Yu Tung) - May be requested in 6-10 wks (1) 1
Engineering & Comp. Sci. - Periodical Stacks (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Engineering & Comp. Sci. - Special Collections (1) 1
Faculty of Information - Juvenile (1) 1
Law (Bora Laskin) - Stacks (1) 1
Law (Bora Laskin) - Theses (1) 1
Massey College (Robertson Davies) - Rare Book (1) 1
OISE - Children's Literature (1) 1
OISE - Stacks (1) 1
Robarts - Gov Pub Storage: Request at Reference Desk 4th floor (1) 1
Robarts - Not Returned (1) 1
Royal Ontario Museum - Stacks (1) 1
UofT Schools - Special Collections (1) 1
Victoria University CRRS - Library use only (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1344998) 1344998
Chinese (222152) 222152
French (130078) 130078
German (78700) 78700
Korean (57600) 57600
Japanese (54743) 54743
Russian (12453) 12453
Finnish (2602) 2602
Spanish (2132) 2132
Swedish (2129) 2129
Polish (1540) 1540
Czech (1210) 1210
Italian (1053) 1053
Norwegian (1022) 1022
Ukrainian (655) 655
Dutch (593) 593
Portuguese (570) 570
Danish (431) 431
Hungarian (381) 381
Slovenian (315) 315
Greek (265) 265
Hebrew (231) 231
Slovak (217) 217
Bulgarian (146) 146
Croatian (141) 141
Romanian (129) 129
Serbian (71) 71
Lithuanian (62) 62
Estonian (57) 57
Indonesian (52) 52
Latvian (41) 41
Turkish (37) 37
Arabic (16) 16
Icelandic (8) 8
Moldavian (8) 8
Persian (6) 6
Bosnian (5) 5
Catalan (2) 2
Amharic (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Metabolism, ISSN 1550-4131, 2006, Volume 3, Issue 5, pp. 343 - 353
Although the class I phosphoinositide 3-kinase (PI3K) pathway is central to the metabolic actions of insulin, its mechanism of action is not well understood.... 
SIGNALING
Journal Article
Science Signaling, ISSN 1945-0877, 01/2018, Volume 11, Issue 513, p. eaas9779
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47936
Glucagon-like peptide-1 (GLP-1) released from intestinal L cells in response to nutrients has many physiological effects but particularly enhances... 
PATHWAYS | CELLS | ACTIVATION | HEALTHY-SUBJECTS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DEGRADATION | SMALL-MOLECULE AGONISTS | SECRETION | GASTRIC-INHIBITORY POLYPEPTIDE | TYPE-2 DIABETES-MELLITUS | Receptors, Glucagon - antagonists & inhibitors | Calcium - metabolism | Allosteric Regulation | Humans | Peptide Fragments - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Sulfones - pharmacology | Extracellular Signal-Regulated MAP Kinases - genetics | Quinoxalines - pharmacology | Peptides - metabolism | Transfection | Biotransformation | Adenosine Monophosphate - biosynthesis | Receptors, Glucagon - agonists | Cell Line | Gene Expression | Peptide Fragments - metabolism | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 1 - analogs & derivatives | Glucagon-Like Peptide 1 - pharmacology | Rats | Receptors, Glucagon - metabolism | Peptides - pharmacology | Insulin - metabolism | Animals | Glucagon-Like Peptide-1 Receptor | Calcium Signaling - drug effects | Type 2 diabetes | Care and treatment | Glucagon | Metabolites | Physiological aspects | Research | Risk factors | Physiological effects | Peptides | Insulinoma | Systematic review | Hormones | Glucose | Peptide hormones | Calcium signalling | Proteins | Allosteric properties | Intestine | Penicillin | Nutrients | Physiology | Glucagon-like peptide 1 | Recombinant | Peptidase | AMP | Diabetes mellitus | Extracellular signal-regulated kinase | Pharmacology | L cells | Insulin | Affinity | Ligands | Diabetes | Calcium (extracellular)
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, p. e36800
The dysregulation of receptor protein tyrosine kinase (RPTK) function can result in changes in cell proliferation, cell growth and metastasis leading to... 
TYROSINE KINASE TYRO3 | APOPTOTIC CELLS | PI3 KINASE | BIOLOGY | SURVIVAL ACTIVITIES | FAMILY RECEPTORS | SMOOTH-MUSCLE-CELLS | TAM RECEPTORS | GROWTH-FACTOR | PROTEIN-S | ARREST-SPECIFIC GENE | Proto-Oncogene Proteins - metabolism | Cell Line | Up-Regulation | Phosphorylation | Cell Proliferation | Signal Transduction | Intercellular Signaling Peptides and Proteins - genetics | Rats | Proto-Oncogene Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | Receptor Protein-Tyrosine Kinases - metabolism | MAP Kinase Signaling System | Intercellular Signaling Peptides and Proteins - metabolism | Animals | Transfection | Receptor Protein-Tyrosine Kinases - genetics | c-Mer Tyrosine Kinase | Tyrosine | Protein kinases | Mitogens | Analysis | Cell proliferation | Transformation | Immunoprecipitation | Kinases | Metastases | Axl protein | Skin cancer | Proteins | Signal transduction | Receptors | Cell activation | Cell growth | Rodents | Fibroblasts | Protein-tyrosine kinase receptors | Growth factors | Protein-tyrosine kinase | Immunoglobulins | Immune response | Melanoma | Extracellular signal-regulated kinase | MAP kinase | 1-Phosphatidylinositol 3-kinase | Polymerase chain reaction | Studies | Signaling | Molecular modelling | Inhibitors | Mutagenesis | Transformations (mathematics) | Receptor mechanisms | Tumors
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 4, p. e0154638
[This corrects the article DOI: 10.1371/journal.pone.0147830.]. 
Signaling
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e21549
Background: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense... 
TUMOR PH | ACTIVATED PROTEIN-KINASE | CARDIAC-ARREST | CYTOPLASMIC PH | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR PH | PHOSPHATIDIC-ACID | TUBEROUS SCLEROSIS | CELL-GROWTH | EXTRACELLULAR PH | HUMAN CANCER | Phosphorylation - physiology | Cell Line | Tumor Suppressor Proteins - metabolism | Humans | Multiprotein Complexes | Signal Transduction - genetics | Mechanistic Target of Rapamycin Complex 1 | Proteins - genetics | Phosphorylation - genetics | Animals | Proteins - metabolism | Tumor Suppressor Proteins - genetics | Cell Line, Tumor | Signal Transduction - physiology | TOR Serine-Threonine Kinases | Hydrogen-Ion Concentration | Tuberous sclerosis | Protein biosynthesis | Hydrogen-ion concentration | Protein kinases | Tuberous sclerosis 2 protein | Drugs | Cell culture | Phosphorylation | Brain cancer | Acidification | Raf protein | AKT protein | Cytotoxicity | Hamartin | Biosynthesis | Biochemistry | Kinases | pH effects | TSC1 protein | Autophagy | Proteins | Breast carcinoma | Signal transduction | Pathways | Hydrogen ions | Immunotherapy | Fibroblasts | Physiology | Vascular endothelial growth factor | Starvation | Extracellular signal-regulated kinase | Energy expenditure | Substrate inhibition | Embryo fibroblasts | Metabolism | TSC2 protein | Signaling | Acids | Perfusion | Protein synthesis | Protein kinase | Signal processing | Hypoxia | Molecular biology | Biosensors | Cytoplasm | Tumors
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e16781
Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and posses antitumor activity. Here, we examined... 
CYCLIN-DEPENDENT KINASES | SIGNALING PATHWAYS | INHIBITION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAP KINASES | DEATH | STRESS | TRANSIENT | ESTROGEN-RECEPTOR | Endometrial Neoplasms - enzymology | Apoptosis - drug effects | Humans | Enzyme Activation - drug effects | Flavonoids - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Caspases - biosynthesis | Cell Line, Tumor | Enzyme Induction - drug effects | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Female | Cell Proliferation - drug effects | Flavonoids - pharmacology | Cell Cycle - drug effects | Flavonoids - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cytochrome c | Endometrial cancer | Health aspects | Estrogen | Cancer | Apoptosis | Cell proliferation | Cytochrome | Phosphorylation | Bax protein | Bcl-2 protein | Estrogens | Estrogen receptors | Activation | Kinases | ADP | MAP kinase kinase | Anticancer properties | Cell activation | Cell growth | Antitumor agents | Ribose | Inhibition | Pretreatment | Endometrium | Cyclin-dependent kinases | Extracellular signal-regulated kinase | Caspase | Poly(ADP-ribose) polymerase | MAP kinase | Polymerase | Inhibitors | Cyclin-dependent kinase inhibitor p27
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e35826
Receptor tyrosine kinase signaling cooperates with WNT/beta-catenin signaling in regulating many biological processes, but the mechanisms of their interaction... 
INSULIN | MECHANISM | BIOLOGY | DYSPLASIA | MUTATIONS | WNT | FGFR3 | CANCER | LRP6 | Phosphorylation | Humans | Gene Expression Regulation | Phosphatidylinositol 3-Kinases - metabolism | Glycogen Synthase Kinase 3 - metabolism | Wnt Proteins - metabolism | Receptor Protein-Tyrosine Kinases | beta Catenin - metabolism | Proto-Oncogene Proteins c-akt - genetics | beta Catenin - genetics | Phosphatidylinositol 3-Kinases - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Glycogen Synthase Kinase 3 - genetics | Wnt Signaling Pathway - genetics | HEK293 Cells | Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Mitogen-Activated Protein Kinases - metabolism | Wnt protein | AKT protein | Biology | Kinases | Throat cancer | Proteins | Signal transduction | β-catenin | Immunology | TrkA protein | Protein-tyrosine kinase receptors | Physiology | Standard deviation | Protein-tyrosine kinase | Fibroblast growth factor receptor 2 | Tyrosine | Epidermal growth factor receptors | Extracellular signal-regulated kinase | MAP kinase | Biophysics | Cadherin | Biological activity | 1-Phosphatidylinositol 3-kinase | Golgi apparatus | Medicine | Signaling | Low density lipoprotein receptors | Mutation | Prostate cancer | Fibroblast growth factor receptors | Tumors
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, p. e62705
Background: A-kinase anchoring proteins (AKAPs) are scaffolding molecules that coordinate and integrate G-protein signaling events to regulate development,... 
PROTEIN-KINASE-A | BREAST-CANCER | CELL INVASIVENESS | MULTIDISCIPLINARY SCIENCES | HEART-FAILURE | MOUSE | EXCHANGE FACTOR AKAP13 | RECEPTOR | INDUCED CARDIOMYOCYTE HYPERTROPHY | ANCHORING PROTEIN | SIGNALING COMPLEX | Embryo, Mammalian | Minor Histocompatibility Antigens | Heart - embryology | Myocardial Contraction - drug effects | Male | A Kinase Anchor Proteins - genetics | Gene Expression Regulation, Developmental | Guanine Nucleotide Exchange Factors - metabolism | Electrocardiography | Female | A Kinase Anchor Proteins - metabolism | Heart - physiopathology | Protein Structure, Tertiary | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Breeding | Cardiomegaly - physiopathology | Organ Size | Stroke Volume - drug effects | Mice, Transgenic | Animals | Cardiomegaly - chemically induced | Heart - drug effects | Mice | Isoproterenol - adverse effects | Cardiomegaly - metabolism | Heart | Protein kinase A | Cell culture | Cardiovascular disease | Isoproterenol | Kinases | Guanine | Defects | Eutrophication | Proteins | Embryogenesis | Fertility | Rodents | Physiology | Guanine nucleotide exchange factor | Heart diseases | Anchoring | Pharmaceutical sciences | Heart failure | Contractility | Cardiomyocytes | Pharmacology | Breast cancer | Embryos | Muscle contraction | Signaling | Scaffolding | Isoforms | Mutation | Alzheimers disease | Viability | Binding sites | Hypertrophy | Ejection
Journal Article