X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Patent (1285857) 1285857
Journal Article (322056) 322056
Book Chapter (4031) 4031
Conference Proceeding (2791) 2791
Dissertation (2098) 2098
Magazine Article (1077) 1077
Book / eBook (899) 899
Newspaper Article (668) 668
Government Document (543) 543
Publication (497) 497
Web Resource (261) 261
Trade Publication Article (253) 253
Newsletter (98) 98
Book Review (96) 96
Reference (87) 87
Streaming Video (65) 65
Archival Material (46) 46
Standard (30) 30
Paper (25) 25
Journal / eJournal (16) 16
Transcript (11) 11
Microfilm (7) 7
Art (1) 1
Data Set (1) 1
Painting (1) 1
Report (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
physics (1086124) 1086124
signalling (1051422) 1051422
alarm systems (515238) 515238
order telegraphs (515200) 515200
signalling or calling systems (515200) 515200
transporting (421210) 421210
performing operations (421207) 421207
vehicles in general (364295) 364295
traffic control systems (356787) 356787
electricity (350282) 350282
testing (284095) 284095
measuring (283821) 283821
arrangement of signalling or lighting devices, the mounting orsupporting thereof or circuits therefor, for vehicles ingeneral (260093) 260093
electric communication technique (258727) 258727
transmission systems for measured values, control or similarsignals (204287) 204287
computing (191122) 191122
counting (191117) 191117
calculating (191110) 191110
animals (153233) 153233
humans (143483) 143483
vehicles, vehicle fittings, or vehicle parts, not otherwiseprovided for (101214) 101214
navigation (101059) 101059
surveying (100959) 100959
gyroscopic instruments (100942) 100942
measuring distances, levels or bearings (100942) 100942
photogrammetry or videogrammetry (100942) 100942
mechanical engineering (100443) 100443
lighting (100376) 100376
heating (100339) 100339
weapons (100332) 100332
blasting (100316) 100316
electric digital data processing (81109) 81109
pictorial communication, e.g. television (77395) 77395
mice (73115) 73115
human necessities (73028) 73028
signal transduction (72792) 72792
education (69732) 69732
advertising (69115) 69115
cryptography (69091) 69091
display (69076) 69076
seals (69042) 69042
radio navigation (65332) 65332
analogous arrangements using other waves (65330) 65330
determining distance or velocity by use of radio waves (65330) 65330
locating or presence-detecting by use of the reflection orreradiation of radio waves (65330) 65330
radio direction-finding (65330) 65330
wireless communications networks (63770) 63770
transmission of digital information, e.g. telegraphiccommunication (62212) 62212
cell biology (61685) 61685
handling record carriers (60909) 60909
presentation of data (60909) 60909
recognition of data (60909) 60909
record carriers (60909) 60909
controlling (58300) 58300
regulating (58300) 58300
biochemistry & molecular biology (56584) 56584
transmission (56081) 56081
male (53404) 53404
data processing systems or methods, specially adapted foradministrative, commercial, financial, managerial, supervisoryor forecasting purposes (52256) 52256
systems or methods specially adapted for administrative,commercial, financial, managerial, supervisory or forecastingpurposes, not otherwise provided for (52256) 52256
conjoint control of vehicle sub-units of different type ordifferent function (52254) 52254
control systems specially adapted for hybrid vehicles (52254) 52254
road vehicle drive control systems for purposes not related tothe control of a particular sub-unit (52254) 52254
signaling (52245) 52245
proteins (51481) 51481
basic electric elements (49082) 49082
general tagging of cross-sectional technologies spanning over several sections of the ipc (48589) 48589
general tagging of new technological developments (48589) 48589
technical subjects covered by former uspc cross-reference art collections [xracs] and digests (48589) 48589
expression (48088) 48088
fixed constructions (47466) 47466
checking-devices (47106) 47106
female (46087) 46087
telephonic communication (45424) 45424
non-portable lighting devices (45064) 45064
systems thereof (45064) 45064
vehicle lighting devices specially adapted for vehicleexteriors (45064) 45064
functional features or details of lighting devices or systemsthereof (42888) 42888
structural combinations of lighting devices with otherarticles, not otherwise provided for (42888) 42888
selecting (41806) 41806
activation (41681) 41681
phosphorylation (41601) 41601
apoptosis (40582) 40582
gene expression (39572) 39572
diagrams (38220) 38220
appliances for teaching, or communicating with, the blind,deaf or mute (38215) 38215
educational or demonstration appliances (38215) 38215
globes (38215) 38215
planetaria (38215) 38215
image data processing or generation, in general (34642) 34642
hygiene (34539) 34539
medical or veterinary science (34484) 34484
identification (34260) 34260
rats (33584) 33584
arrangements for measuring two or more variables not coveredin a single other subclass (32964) 32964
measuring not specially adapted for a specific variable (32964) 32964
measuring or testing not otherwise provided for (32964) 32964
tariff metering apparatus (32964) 32964
land vehicles for travelling otherwise than on rails (32351) 32351
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Online Resources - Online (270) 270
Gerstein Science - Stacks (163) 163
Collection Dvlpm't (Acquisitions) - Vendor file (57) 57
Robarts - Stacks (52) 52
UTL at Downsview - May be requested (50) 50
Engineering & Comp. Sci. - Stacks (46) 46
UofT at Mississauga - Stacks (40) 40
Collection Dvlpm't (Acquisitions) - Closed Orders (23) 23
UofT at Scarborough - Stacks (19) 19
Media Commons - Microtexts (11) 11
Earth Sciences (Noranda) - Stacks (5) 5
Chemistry (A D Allen) - Stacks (4) 4
Robarts - Government Pubs (4) 4
East Asian (Cheng Yu Tung) - Stacks (3) 3
Music - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (3) 3
Thomas Fisher Rare Book - Rare Book (3) 3
Trinity College (John W Graham) - Stacks (3) 3
Engineering & Comp. Sci. - May be requested in 6-10 wks (2) 2
Engineering & Comp. Sci. - Periodical Stacks (2) 2
Gerstein Science - Periodical Stacks (2) 2
Mathematical Sciences - Stacks (2) 2
St. Michael's College (John M. Kelly) - 2nd Floor (2) 2
Victoria University E.J. Pratt - Stacks (2) 2
Architecture Landscape (Shore + Moffat) - Stacks (1) 1
Art - Library use only (1) 1
Collection Dvlpm't (Acquisitions) - Cancelled Order (1) 1
East Asian (Cheng Yu Tung) - May be requested in 6-10 wks (1) 1
Engineering & Comp. Sci. - Reference (1) 1
Engineering & Comp. Sci. - Special Collections (1) 1
Faculty of Information - Juvenile (1) 1
Law (Bora Laskin) - Stacks (1) 1
Law (Bora Laskin) - Theses (1) 1
Massey College (Robertson Davies) - Rare Book (1) 1
OISE - Children's Literature (1) 1
OISE - Stacks (1) 1
Physics - Stacks (1) 1
Robarts - Gov Pub Storage: Request at Reference Desk 4th floor (1) 1
Robarts - Not Returned (1) 1
Robarts - Storage (1) 1
Royal Ontario Museum - Stacks (1) 1
UofT Schools - Special Collections (1) 1
UofT at Scarborough - May be requested in 6-10 wks (1) 1
Victoria University CRRS - Library use only (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (1412661) 1412661
Chinese (244508) 244508
French (179515) 179515
German (165377) 165377
Japanese (61823) 61823
Korean (56840) 56840
Spanish (19029) 19029
Russian (12388) 12388
Portuguese (9003) 9003
Italian (7766) 7766
Swedish (4710) 4710
Finnish (2628) 2628
Danish (2257) 2257
Dutch (2070) 2070
Norwegian (1823) 1823
Polish (1651) 1651
Czech (1302) 1302
Ukrainian (654) 654
Romanian (580) 580
Turkish (570) 570
Hungarian (387) 387
Slovenian (315) 315
Greek (267) 267
Slovak (228) 228
Hebrew (226) 226
Bulgarian (149) 149
Croatian (141) 141
Serbian (72) 72
Lithuanian (68) 68
Arabic (57) 57
Estonian (56) 56
Indonesian (56) 56
Latvian (41) 41
Icelandic (8) 8
Moldavian (8) 8
Persian (8) 8
Bosnian (5) 5
Catalan (3) 3
Amharic (1) 1
Welsh (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cell Metabolism, ISSN 1550-4131, 2006, Volume 3, Issue 5, pp. 343 - 353
Although the class I A phosphoinositide 3-kinase (PI3K) pathway is central to the metabolic actions of insulin, its mechanism of action is not well understood.... 
SIGNALING
Journal Article
Neuro-Oncology, ISSN 1522-8517, 04/2019, Volume 21, Issue Supplement_2, pp. ii113 - ii113
Abstract The metastatic potential of tumors depends in part on their response to growth factors available in the tumor microenvironment. We addressed how... 
Signalling
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e47936
Glucagon-like peptide-1 (GLP-1) released from intestinal L cells in response to nutrients has many physiological effects but particularly enhances... 
PATHWAYS | CELLS | ACTIVATION | HEALTHY-SUBJECTS | MULTIDISCIPLINARY SCIENCES | IN-VIVO | DEGRADATION | SMALL-MOLECULE AGONISTS | SECRETION | GASTRIC-INHIBITORY POLYPEPTIDE | TYPE-2 DIABETES-MELLITUS | Receptors, Glucagon - antagonists & inhibitors | Calcium - metabolism | Allosteric Regulation | Humans | Peptide Fragments - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | Sulfones - pharmacology | Extracellular Signal-Regulated MAP Kinases - genetics | Quinoxalines - pharmacology | Peptides - metabolism | Transfection | Biotransformation | Adenosine Monophosphate - biosynthesis | Receptors, Glucagon - agonists | Cell Line | Gene Expression | Peptide Fragments - metabolism | Glucagon-Like Peptide 1 - metabolism | Glucagon-Like Peptide 1 - analogs & derivatives | Glucagon-Like Peptide 1 - pharmacology | Rats | Receptors, Glucagon - metabolism | Peptides - pharmacology | Insulin - metabolism | Animals | Glucagon-Like Peptide-1 Receptor | Calcium Signaling - drug effects | Type 2 diabetes | Care and treatment | Glucagon | Metabolites | Physiological aspects | Research | Risk factors | Physiological effects | Peptides | Insulinoma | Systematic review | Hormones | Glucose | Peptide hormones | Calcium signalling | Proteins | Allosteric properties | Intestine | Penicillin | Nutrients | Physiology | Glucagon-like peptide 1 | Peptidase | AMP | Diabetes mellitus | Extracellular signal-regulated kinase | Pharmacology | L cells | Insulin | Affinity | Ligands | Diabetes | Calcium (extracellular) | Recombinant
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 5, p. e36800
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 6, p. e21549
Background: Acidification of the cytoplasm and the extracellular environment is associated with many physiological and pathological conditions, such as intense... 
TUMOR PH | ACTIVATED PROTEIN-KINASE | CARDIAC-ARREST | CYTOPLASMIC PH | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR PH | PHOSPHATIDIC-ACID | TUBEROUS SCLEROSIS | CELL-GROWTH | EXTRACELLULAR PH | HUMAN CANCER | Phosphorylation - physiology | Cell Line | Tumor Suppressor Proteins - metabolism | Humans | Multiprotein Complexes | Signal Transduction - genetics | Mechanistic Target of Rapamycin Complex 1 | Proteins - genetics | Phosphorylation - genetics | Animals | Proteins - metabolism | Tumor Suppressor Proteins - genetics | Cell Line, Tumor | Signal Transduction - physiology | TOR Serine-Threonine Kinases | Hydrogen-Ion Concentration | Tuberous sclerosis | Protein biosynthesis | Hydrogen-ion concentration | Protein kinases | Drugs | Cell culture | Phosphorylation | Tuberous Sclerosis Complex 2 | Brain cancer | Acidification | Raf protein | AKT protein | Cytotoxicity | Biosynthesis | Biochemistry | Kinases | pH effects | Autophagy | Tuberous Sclerosis Complex 1 | Proteins | Breast carcinoma | Signal transduction | Pathways | Hydrogen ions | Immunotherapy | Fibroblasts | Physiology | Vascular endothelial growth factor | Starvation | Extracellular signal-regulated kinase | Energy expenditure | Substrate inhibition | Embryo fibroblasts | Metabolism | Signaling | Acids | Perfusion | Protein synthesis | Protein kinase | Signal processing | Hypoxia | Molecular biology | Biosensors | Cytoplasm | Tumors
Journal Article
PloS one, ISSN 1932-6203, 2016, Volume 11, Issue 4, p. e0154638
[This corrects the article DOI: 10.1371/journal.pone.0147830.]. 
Signaling
Journal Article
PloS one, ISSN 1932-6203, 2011, Volume 6, Issue 3, p. e16781
Icaritin, a compound from Epimedium Genus, has selective estrogen receptor (ER) modulating activities, and posses antitumor activity. Here, we examined... 
CYCLIN-DEPENDENT KINASES | SIGNALING PATHWAYS | INHIBITION | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAP KINASES | DEATH | STRESS | TRANSIENT | ESTROGEN-RECEPTOR | Endometrial Neoplasms - enzymology | Apoptosis - drug effects | Humans | Enzyme Activation - drug effects | Flavonoids - therapeutic use | Proto-Oncogene Proteins c-bcl-2 - metabolism | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Caspases - biosynthesis | Cell Line, Tumor | Enzyme Induction - drug effects | Endometrial Neoplasms - drug therapy | Endometrial Neoplasms - pathology | Female | Cell Proliferation - drug effects | Flavonoids - pharmacology | Cell Cycle - drug effects | Flavonoids - chemistry | Mitogen-Activated Protein Kinase 1 - metabolism | Cytochrome c | Endometrial cancer | Health aspects | Estrogen | Cancer | Apoptosis | Cell proliferation | Cytochrome | Phosphorylation | Bax protein | Bcl-2 protein | Estrogens | Estrogen receptors | Activation | Kinases | MAP kinase kinase | Anticancer properties | Cell activation | Cell growth | Antitumor agents | Ribose | Inhibition | Pretreatment | Endometrium | Cyclin-dependent kinases | Extracellular signal-regulated kinase | Caspase | Poly(ADP-ribose) polymerase | Adenosine diphosphate | MAP kinase | Polymerase | Inhibitors | Cyclin-dependent kinase inhibitor p27
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, p. e92917
It has been proposed that differential activation kinetics allows cells to use a common set of signaling pathways to specify distinct cellular outcomes. For... 
PHEOCHROMOCYTOMA CELLS | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | MAP KINASE | MULTIDISCIPLINARY SCIENCES | NEURONAL DIFFERENTIATION | MAMMALIAN-CELLS | PLASMA-MEMBRANE | NUCLEAR TRANSLOCATION | NERVE GROWTH-FACTOR | LIVING CELLS | NIH 3T3 Cells | Protein Transport - drug effects | Extracellular Signal-Regulated MAP Kinases - metabolism | raf Kinases - metabolism | PC12 Cells | Light | Cell Membrane - metabolism | Cell Membrane - drug effects | Neurites - drug effects | Cell Membrane - radiation effects | Cryptochromes - metabolism | Cell Differentiation - radiation effects | Protein Structure, Tertiary | MAP Kinase Signaling System - radiation effects | Proto-Oncogene Proteins c-raf | Nerve Growth Factor - pharmacology | Rats | MAP Kinase Kinase Kinases - metabolism | Neurites - metabolism | Enzyme Activation - drug effects | Enzyme Activation - radiation effects | Animals | MAP Kinase Signaling System - drug effects | Cell Differentiation - drug effects | Protein Transport - radiation effects | Cryptochromes - chemistry | Mice | Kinetics | Dose-Response Relationship, Radiation | Neurites - radiation effects | Nerve growth factor | Cellular signal transduction | Epidermal growth factor | Protein-protein interactions | Phosphorylation | Raf protein | Stimulation | Activation | Kinases | Proteins | Signal transduction | Cell growth | Cell cycle | Localization | Growth factors | Axonogenesis | Extracellular signal-regulated kinase | Gene expression | Studies | Signaling | Cell lines | Pheochromocytoma cells | Transduction | Genetic engineering | Protein interaction
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2012, Volume 7, Issue 4, p. e35826
Receptor tyrosine kinase signaling cooperates with WNT/beta-catenin signaling in regulating many biological processes, but the mechanisms of their interaction... 
INSULIN | MUTATIONS | MECHANISM | WNT | FGFR3 | MULTIDISCIPLINARY SCIENCES | Phosphorylation | Humans | Gene Expression Regulation | Phosphatidylinositol 3-Kinases - metabolism | Glycogen Synthase Kinase 3 - metabolism | Wnt Proteins - metabolism | Receptor Protein-Tyrosine Kinases | beta Catenin - metabolism | Proto-Oncogene Proteins c-akt - genetics | beta Catenin - genetics | Phosphatidylinositol 3-Kinases - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - genetics | Low Density Lipoprotein Receptor-Related Protein-6 - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Glycogen Synthase Kinase 3 - genetics | Wnt Signaling Pathway - genetics | HEK293 Cells | Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Mitogen-Activated Protein Kinases - metabolism | Wnt protein | AKT protein | Biology | Kinases | Throat cancer | Proteins | Signal transduction | β-catenin | Immunology | TrkA protein | Protein-tyrosine kinase receptors | Physiology | Standard deviation | Protein-tyrosine kinase | Fibroblast growth factor receptor 2 | Tyrosine | Epidermal growth factor receptors | Extracellular signal-regulated kinase | MAP kinase | Biophysics | Cadherin | Biological activity | 1-Phosphatidylinositol 3-kinase | Golgi apparatus | Medicine | Signaling | Low density lipoprotein receptors | Mutation | Prostate cancer | Fibroblast growth factor receptors | Tumors
Journal Article
The Journal of neuroscience, ISSN 1529-2401, 2017, Volume 37, Issue 7, pp. 1772 - 1784
Triggering Receptor Expressed on Myeloid cells 2 (TREM2), which is expressed on myeloid cells including microglia in the CNS, has recently been identified as a... 
Akt/GSK3β signaling pathway | TREM2 | Cell survival | Alzheimer’s disease | Wnt/β-catenin signaling pathway | Microglia | NEURODEGENERATIVE DISEASE | NERVOUS-SYSTEM | CELLS | cell survival | ALZHEIMERS-DISEASE | AMYLOID PLAQUES | PROLIFERATION | BETA-CATENIN | NEUROSCIENCES | Wnt/beta-catenin signaling pathway | SIGNALING PATHWAY | PSEUDOMONAS-AERUGINOSA | Akt/GSK3 beta signaling pathway | IN-VIVO | Alzheimer's disease | microglia | Cell Cycle - genetics | Cyclin D1 - metabolism | Microglia - metabolism | Adjuvants, Immunologic - pharmacology | Membrane Glycoproteins - metabolism | Caspase 3 - metabolism | Cell Survival - genetics | Wnt Signaling Pathway - physiology | Male | Proteolysis - drug effects | Lithium Chloride - pharmacology | Thiadiazoles - pharmacology | Animals, Newborn | Cell Survival - drug effects | Brain - cytology | Microglia - drug effects | Gene Expression Regulation - genetics | Kainic Acid - pharmacology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Excitatory Amino Acid Agonists - pharmacology | beta Catenin - metabolism | Membrane Glycoproteins - genetics | Gene Expression Regulation - drug effects | Animals | Wnt Signaling Pathway - drug effects | Cyclin D1 - genetics | Mice | Cell Cycle - drug effects | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | β-catenin signaling pathway | GSK3β signaling pathway | Akt | Wnt
Journal Article