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PLoS Pathogens, ISSN 1553-7366, 2015, Volume 11, Issue 9, pp. e1005153 - e1005153
Two of the crucial aspects of human immunodeficiency virus (HIV) infection are (i) viral persistence in reservoirs (precluding viral eradication) and (ii)... 
LONG-TERM NONPROGRESSORS | MESSENGER-RNA EXPRESSION | MICROBIOLOGY | NECROSIS-FACTOR-ALPHA | HUMAN-IMMUNODEFICIENCY-VIRUS | HUMAN ADIPOCYTES | VIROLOGY | ACTIVE ANTIRETROVIRAL THERAPY | SIVMAC251 INFECTION | IMMUNE ACTIVATION | METABOLIC-DISORDERS | MEMORY T-CELLS | PARASITOLOGY | Simian Acquired Immunodeficiency Syndrome - metabolism | HIV - physiology | Stromal Cells - pathology | Coculture Techniques | Humans | Middle Aged | Macaca fascicularis | Male | HIV - immunology | Adipose Tissue - immunology | CD4-Positive T-Lymphocytes - pathology | CD4-Positive T-Lymphocytes - immunology | Simian Immunodeficiency Virus - isolation & purification | Adipose Tissue - metabolism | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Macrophages - virology | HIV Infections - pathology | Stromal Cells - virology | Adult | Female | Panniculitis - immunology | Disease Reservoirs | CD4-Positive T-Lymphocytes - virology | Simian Acquired Immunodeficiency Syndrome - pathology | Macrophages - immunology | Simian Immunodeficiency Virus - immunology | Macrophages - pathology | Adipose Tissue - virology | HIV Infections - virology | Stromal Cells - metabolism | Adipose Tissue - pathology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Stromal Cells - immunology | HIV - isolation & purification | Immunity, Innate | Panniculitis - virology | Simian Immunodeficiency Virus - physiology | Host-Pathogen Interactions | Macrophages - metabolism | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | Aged | Panniculitis - pathology | Panniculitis - metabolism | HIV Infections - metabolism | Adipose tissues | Host-virus relationships | HIV (Viruses) | Simian immunodeficiency virus | Observations | Health aspects | Index Medicus | Life Sciences | Human health and pathology | Antiretroviral drugs | Lymphatic system | Mortality | Infections | Inflammation | Adipocytes | Metabolism | Experiments | HIV | Lymphocytes | Rodents | Deoxyribonucleic acid | DNA | Human immunodeficiency virus | Drug therapy
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2015, Volume 195, Issue 9, pp. 4351 - 4357
CD4(+) T follicular helper (Tfh) cells are critical for the generation of humoral immune responses to pathogenic infections, providing help for B cell... 
TFH CELLS | DISEASE | DYNAMICS | DEATH | MACAQUES | DIFFERENTIATION | DYSFUNCTION | TISSUES | IMMUNOLOGY | CORRELATE | Simian Acquired Immunodeficiency Syndrome - metabolism | Coculture Techniques | Germinal Center - immunology | Humans | Macaca mulatta - immunology | Host-Pathogen Interactions - immunology | Lymphoid Tissue - immunology | T-Lymphocytes, Helper-Inducer - virology | CD4-Positive T-Lymphocytes - immunology | Acquired Immunodeficiency Syndrome - immunology | Macaca mulatta - virology | Simian Acquired Immunodeficiency Syndrome - virology | Flow Cytometry | T-Lymphocytes, Helper-Inducer - immunology | B-Lymphocytes - virology | CD4-Positive T-Lymphocytes - virology | Acquired Immunodeficiency Syndrome - virology | B-Lymphocytes - metabolism | Simian Immunodeficiency Virus - immunology | Acquired Immunodeficiency Syndrome - metabolism | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Lymphoid Tissue - virology | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Lymph Nodes - metabolism | Lymphoid Tissue - metabolism | Programmed Cell Death 1 Receptor - metabolism | Virus Replication - immunology | Lymph Nodes - virology | Lymph Nodes - immunology | Receptors, CXCR5 - immunology | Simian Immunodeficiency Virus - physiology | Microscopy, Confocal | Animals | B-Lymphocytes - immunology | Germinal Center - metabolism | Simian Acquired Immunodeficiency Syndrome - immunology | Germinal Center - virology | Programmed Cell Death 1 Receptor - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2016, Volume 113, Issue 24, pp. E3413 - E3422
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 4
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2013, Volume 9, Issue 7, pp. e1003471 - e1003471
In pathogenic HIV and SIV infections of humans and rhesus macaques (RMs), preferential depletion of CD4(+) Th17 cells correlates with mucosal immune... 
GASTROINTESTINAL-TRACT | SOOTY MANGABEYS | MICROBIOLOGY | ANTIRETROVIRAL THERAPY | CHRONIC VIRAL-INFECTION | VIRUS TYPE-1 INFECTION | CD8 T-CELLS | METASTATIC MELANOMA | HIV-INFECTION | VIROLOGY | LENTIVIRAL INFECTIONS | IMMUNE ACTIVATION | PARASITOLOGY | Simian Acquired Immunodeficiency Syndrome - metabolism | Perforin - genetics | Recombinant Fusion Proteins - adverse effects | Granzymes - metabolism | Recombinant Fusion Proteins - therapeutic use | Macaca mulatta | Granzymes - genetics | Bacterial Translocation - drug effects | Th17 Cells - virology | Intestinal Mucosa - drug effects | Immunity, Mucosal - drug effects | Simian Immunodeficiency Virus - isolation & purification | Interleukins - genetics | Simian Acquired Immunodeficiency Syndrome - virology | Th17 Cells - drug effects | Intestinal Mucosa - immunology | CD8-Positive T-Lymphocytes - metabolism | Female | Granzymes - biosynthesis | Immunoglobulin Fc Fragments - therapeutic use | Immunoglobulin Fc Fragments - adverse effects | Th17 Cells - pathology | Interleukins - therapeutic use | Intestinal Mucosa - virology | Random Allocation | Down-Regulation - drug effects | Interleukins - adverse effects | Simian Immunodeficiency Virus - physiology | Up-Regulation - drug effects | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Simian Acquired Immunodeficiency Syndrome - immunology | Cell Differentiation - drug effects | CD8-Positive T-Lymphocytes - drug effects | Recombinant Fusion Proteins - genetics | Th17 Cells - immunology | Perforin - metabolism | CD8-Positive T-Lymphocytes - immunology | Viral Load - drug effects | Immunoglobulin Fc Fragments - genetics | Simian Immunodeficiency Virus - drug effects | Intestinal Mucosa - pathology | Perforin - biosynthesis | Rhesus monkey | Translocation (Genetics) | Interleukins | Physiological aspects | Host-parasite relationships | Genetic aspects | Research | Simian immunodeficiency virus | HIV (Viruses) | Health aspects | Index Medicus | Antiretroviral drugs | HIV | Acquired immune deficiency syndrome | AIDS | Human immunodeficiency virus | Drug therapy | Immune system
Journal Article
Journal of Virology, ISSN 0022-538X, 2017, Volume 91, Issue 4, pp. e01626 - 16
African green monkeys (AGM) and sooty mangabeys (SM) are wellstudied natural hosts of simian immunodeficiency virus (SIV) that do not progress to AIDS when... 
Tropism | Natural host | Coreceptor | CXCR6 | Simian immunodeficiency virus | African green monkey | tropism | coreceptor | CD4(+) T-CELLS | simian immunodeficiency virus | natural host | VIROLOGY | LENTIVIRAL INFECTIONS | IN-VIVO | IMMUNE ACTIVATION | CORECEPTOR USAGE | EXPRESSION PATTERN | AETHIOPS-SABAEUS | HIV-1 INFECTION | MICROBIAL TRANSLOCATION | SIV INFECTION | Simian Acquired Immunodeficiency Syndrome - metabolism | Receptors, Virus - metabolism | Cercopithecus aethiops | Receptors, CCR5 - genetics | Phylogeny | Virus Internalization | CD4-Positive T-Lymphocytes - immunology | Receptors, CCR5 - metabolism | Simian Acquired Immunodeficiency Syndrome - virology | Lymphocytes - immunology | Lymphocytes - virology | Cloning, Molecular | Receptors, CCR6 - metabolism | Viral Envelope Proteins - metabolism | Viral Tropism | CD4-Positive T-Lymphocytes - virology | Lymphocytes - metabolism | Simian Immunodeficiency Virus - classification | Viral Envelope Proteins - genetics | CD4-Positive T-Lymphocytes - metabolism | Sequence Analysis, DNA | Simian Immunodeficiency Virus - physiology | Host-Pathogen Interactions | Animals | Simian Acquired Immunodeficiency Syndrome - immunology | Receptors, CCR6 - genetics | Index Medicus | Viral Envelope Proteins | Cellular Biology | Virology | Life Sciences | Microbiology and Parasitology | Simian Acquired Immunodeficiency Syndrome | Lymphocytes | Receptors, CCR5 | Receptors, CCR6 | CD4-Positive T-Lymphocytes | Simian Immunodeficiency Virus | Receptors, Virus
Journal Article
Journal of Immunology, ISSN 0022-1767, 11/2014, Volume 193, Issue 9, pp. 4527 - 4536
Journal Article
Blood, ISSN 0006-4971, 12/2008, Volume 112, Issue 12, pp. 4598 - 4608
Journal Article
JAMA, ISSN 0098-7484, 04/2005, Volume 293, Issue 16, pp. 2003 - 2011
CONTEXT The prevalence of human immunodeficiency virus (HIV) central nervous system (CNS) disease has not decreased despite highly active antiretroviral... 
MEDICINE, GENERAL & INTERNAL | ACTIVATED PROTEIN-KINASE | HIV-INFECTION | MOUSE MODEL | COGNITIVE IMPAIRMENT | CENTRAL-NERVOUS-SYSTEM | ANTIRETROVIRAL THERAPY | GROWTH-FACTOR | CEREBROSPINAL-FLUID | AIDS DEMENTIA | P38 MAP KINASE | Simian Acquired Immunodeficiency Syndrome - metabolism | Central Nervous System - metabolism | AIDS Dementia Complex - prevention & control | Minocycline - pharmacology | Central Nervous System - pathology | HIV - drug effects | Viral Load | Macrophages - virology | Neuroprotective Agents - pharmacology | Lymphocytes - virology | AIDS Dementia Complex - pathology | Chemokine CCL2 - metabolism | Encephalitis, Viral - metabolism | p38 Mitogen-Activated Protein Kinases - metabolism | Simian Acquired Immunodeficiency Syndrome - pathology | Central Nervous System - virology | Disease Models, Animal | Biomarkers - metabolism | Lymphocytes - metabolism | Macaca nemestrina | Virus Replication - drug effects | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Encephalitis, Viral - drug therapy | Macrophages - metabolism | AIDS Dementia Complex - metabolism | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Anti-Bacterial Agents - pharmacology | Encephalitis, Viral - pathology | Simian Immunodeficiency Virus - drug effects | HIV antigens | Minocycline | Research | Clinical trials | Encephalitis | Antiretroviral drugs | Antibiotics | Drug therapy | Human immunodeficiency virus--HIV | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2012, Volume 122, Issue 5, pp. 1712 - 1716
Hyperimmune activation is a strong predictor of disease progression during pathogenic immunodeficiency virus infections and is mediated in part by sustained... 
MEDICINE, RESEARCH & EXPERIMENTAL | TIGHT JUNCTIONS | HIV-INFECTION | CLAUDIN-5 | DISEASE | IMMUNE ACTIVATION | VACCINATION | EXPRESSION | CD8 T-CELLS | Campylobacter - physiology | Simian Acquired Immunodeficiency Syndrome - metabolism | Intestinal Mucosa - metabolism | Shigella - immunology | Humans | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Gene Expression Profiling | Macaca mulatta | Simian Acquired Immunodeficiency Syndrome - microbiology | Intestinal Mucosa - drug effects | Bacteremia - microbiology | Feces - microbiology | Lipopolysaccharides - blood | Trichuris - immunology | Intestine, Large - metabolism | Intestine, Large - microbiology | Feces - parasitology | Intestinal Mucosa - immunology | Antibodies, Neutralizing - therapeutic use | Bacteremia - blood | Interferon Type I - metabolism | Shigella - physiology | Transcription, Genetic | Intestine, Large - drug effects | Antiviral Agents - pharmacology | Signal Transduction | Antiviral Agents - therapeutic use | Salmonella - physiology | Antibodies, Neutralizing - pharmacology | Intestinal Mucosa - microbiology | Bacterial Translocation | Intestine, Large - immunology | Opportunistic Infections - microbiology | Salmonella - immunology | Animals | Simian Acquired Immunodeficiency Syndrome - drug therapy | Simian Acquired Immunodeficiency Syndrome - immunology | Interferon Type I - blood | Interferon Type I - genetics | Simian Immunodeficiency Virus | Programmed Cell Death 1 Receptor - immunology | Trichuris - physiology | Chronic Disease | Campylobacter - immunology | Immune response | Development and progression | Models | Research | Simian immunodeficiency virus | HIV infection | Apoptosis | Index Medicus | Abridged Index Medicus | Brief Report
Journal Article