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Journal of Clinical Investigation, ISSN 0021-9738, 12/2009, Volume 119, Issue 12, pp. 3544 - 3555
African green monkeys (AGMs) infected with the AGM type of SIV (SIVagm) do not develop chronic immune activation and AIDS, despite viral loads similar to those... 
PLASMACYTOID DENDRITIC CELLS | NONHUMAN-PRIMATES | VIRAL LOAD | MEDICINE, RESEARCH & EXPERIMENTAL | HIV-1 IMMUNOPATHOGENESIS | LYMPH-NODES | IMMUNE ACTIVATION | IMMUNODEFICIENCY VIRUS-INFECTION | CD4(+) T-CELLS | AIDS | INTERFERON-PRODUCTION | HIV-1 | Oligonucleotide Array Sequence Analysis | Species Specificity | Humans | Cercopithecus aethiops | Gene Expression Profiling | Macaca mulatta | Host-Pathogen Interactions - immunology | CD4-Positive T-Lymphocytes - immunology | HIV Infections - immunology | Interferon Type I - biosynthesis | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | Interferon-alpha - genetics | Simian Acquired Immunodeficiency Syndrome - genetics | Simian Immunodeficiency Virus - immunology | Simian Immunodeficiency Virus - pathogenicity | Interferon-alpha - biosynthesis | HIV Infections - virology | Simian Immunodeficiency Virus - physiology | Animals | Host-Pathogen Interactions - genetics | Simian Acquired Immunodeficiency Syndrome - immunology | Virus Replication | Virulence - immunology | Interferon Type I - genetics | Development and progression | Interferon | HIV (Viruses) | T cells | Simian immunodeficiency virus | Gene expression | Health aspects | HIV Infections | Virulence | Innate immunity | Life Sciences | Immunology | Immunotherapy | CD4-Positive T-Lymphocytes | Interferon-alpha | Interferon Type I | Virology | Host-Pathogen Interactions | Human health and pathology | Microbiology and Parasitology | Simian Acquired Immunodeficiency Syndrome | Infectious diseases | Simian Immunodeficiency Virus
Journal Article
Nature, ISSN 0028-0836, 12/2016, Volume 540, Issue 7632, pp. 284 - 287
The development of immunologic interventions that can target the viral reservoir in HIV-1-infected individuals is a major goal of HIV-1 research(1,2). However,... 
INDIVIDUALS | VIREMIA | PERSISTENCE | MULTIDISCIPLINARY SCIENCES | ACTIVE ANTIRETROVIRAL THERAPY | MACAQUES | LATENT RESERVOIR | T-CELLS | CHALLENGES | VIRAL RESERVOIR | HIV-1 REMISSION | AIDS Vaccines - immunology | Simian Immunodeficiency Virus - growth & development | DNA, Viral - analysis | Male | RNA, Viral - blood | Macaca mulatta | Vaccinia virus - genetics | Simian Immunodeficiency Virus - isolation & purification | HIV Infections - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | Time Factors | Toll-Like Receptor 7 - immunology | Adenoviridae - genetics | Female | Simian Acquired Immunodeficiency Syndrome - therapy | Simian Immunodeficiency Virus - immunology | Toll-Like Receptor 7 - genetics | RNA, Viral - analysis | Immunity, Innate | Viral Load - immunology | Genetic Vectors - genetics | DNA, Viral - blood | SAIDS Vaccines - genetics | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Anti-Retroviral Agents - administration & dosage | HIV Infections - therapy | AIDS Vaccines - genetics | Immunity, Cellular | Prevention | TLR7 | Dosage and administration | Viral vaccines | Health aspects | HIV infection | Immunization | Adenoviruses | Human immunodeficiency virus--HIV | Viruses | Vaccines | Monkeys & apes | Viral infections | Index Medicus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 05/2009, Volume 5, Issue 5, pp. e1000429 - e1000429
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 6/2016, Volume 113, Issue 24, pp. E3413 - E3422
Journal Article
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 05/2009, Volume 206, Issue 5, pp. 1117 - 1134
Journal Article
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 1371 - 16
HIV-1 causes chronic inflammation and AIDS in humans, whereas related simian immunodeficiency viruses (SIVs) replicate efficiently in their natural hosts... 
SIMIAN-IMMUNODEFICIENCY-VIRUS | MULTIDISCIPLINARY SCIENCES | INFECTED SOOTY MANGABEYS | T-CELL-ACTIVATION | IN-VIVO | AFRICAN-GREEN MONKEYS | CD4 DOWN-REGULATION | HIV-1 VPU INTERFERENCE | NF-KAPPA-B | SIV INFECTION | LYMPHOCYTE-ACTIVATION | Bone Marrow Stromal Antigen 2 - genetics | HIV-1 - pathogenicity | Human Immunodeficiency Virus Proteins - immunology | Humans | Virulence | NF-kappa B - immunology | Cercopithecus aethiops | Simian Immunodeficiency Virus - growth & development | Viral Load | CD3 Complex - genetics | HIV-1 - growth & development | Female | Transcription, Genetic | Bone Marrow Stromal Antigen 2 - immunology | Amino Acid Sequence | Simian Immunodeficiency Virus - pathogenicity | Signal Transduction | Lentiviruses, Primate - growth & development | Lymphocyte Activation | Viral Regulatory and Accessory Proteins - immunology | Viral Regulatory and Accessory Proteins - genetics | Gene Expression Regulation | Host Specificity | Sequence Alignment | Animals | NF-kappa B - genetics | Virus Replication | nef Gene Products, Human Immunodeficiency Virus - genetics | nef Gene Products, Human Immunodeficiency Virus - immunology | CD3 Complex - immunology | Human Immunodeficiency Virus Proteins - genetics | Lentiviruses, Primate - pathogenicity | Pathogens | NF-κB protein | Viremia | Immunodeficiency | Vpu protein | Viruses | Activation | Monkeys | Lymphocytes T | CD3 antigen | Pathogenicity | Cell activation | Nef protein | Acquired immune deficiency syndrome--AIDS | Virulence factors | Transcription activation | Human immunodeficiency virus--HIV | HIV-1 | Viral Regulatory and Accessory Proteins | Life Sciences | NF-kappa B | Immunology | CD3 Complex | Human Immunodeficiency Virus Proteins | Animal biology | Virology | Human health and pathology | Microbiology and Parasitology | Infectious diseases | Lentiviruses, Primate | Bone Marrow Stromal Antigen 2 | Simian Immunodeficiency Virus | nef Gene Products, Human Immunodeficiency Virus
Journal Article
Nature, ISSN 0028-0836, 2014, Volume 505, Issue 7484, pp. 502 - 508
A major challenge for the development of a highly effective AIDS vaccine is the identification of mechanisms of protective immunity. To address this question,... 
NEUTRALIZING ANTIBODIES | CELL RESPONSES | SIMIAN IMMUNODEFICIENCY VIRUS | EFFICACY TRIAL | MULTIDISCIPLINARY SCIENCES | SIVSME660 | PREVENTION | INFECTION | DOSE CHALLENGE EXPERIMENTS | BINDING | RHESUS MACAQUES | HIV Infections - prevention & control | env Gene Products, Human Immunodeficiency Virus - immunology | Humans | AIDS Vaccines - immunology | Molecular Sequence Data | Male | Risk | Macaca mulatta | Phylogeny | Simian Immunodeficiency Virus - chemistry | Founder Effect | HIV Infections - immunology | Antibodies, Neutralizing - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | Disease Susceptibility - immunology | HIV Antibodies - immunology | HIV-1 - chemistry | Female | Simian Immunodeficiency Virus - immunology | Amino Acid Sequence | HIV Infections - virology | Simian Immunodeficiency Virus - physiology | Simian Acquired Immunodeficiency Syndrome - prevention & control | HIV-1 - immunology | Animals | SAIDS Vaccines - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Immune Evasion - immunology | Antigen-antibody reactions | AIDS vaccines | Immune complexes | AIDS (Disease) | Monoclonal antibodies | Physiological aspects | Research | AIDS research | Health aspects | Viruses | Vaccines | Laboratory animals | Cloning | Human immunodeficiency virus--HIV | Deoxyribonucleic acid--DNA
Journal Article
Nature, ISSN 0028-0836, 04/2009, Volume 458, Issue 7241, pp. 1034 - 1038
Although there has been great progress in treating human immunodeficiency virus 1 (HIV-1) infection(1), preventing transmission has thus far proven an elusive... 
RESPONSES | IMMUNITY | EPITHELIAL-CELLS | HIV | SIMIAN IMMUNODEFICIENCY VIRUS | VAGINAL TRANSMISSION | CHEMOKINES | MULTIDISCIPLINARY SCIENCES | INNATE | CD4(+) T-CELLS | INFECTION | Chemokine CCL20 - metabolism | Vagina - drug effects | Dendritic Cells - immunology | GPI-Linked Proteins | Simian Immunodeficiency Virus - growth & development | RNA, Viral - blood | Gene Expression Profiling | Monoglycerides - pharmacology | Body Fluids - virology | Receptors, CCR5 - immunology | CD4-Positive T-Lymphocytes - immunology | Chemokine CCL20 - immunology | Macaca mulatta - virology | Receptors, CCR5 - metabolism | Simian Acquired Immunodeficiency Syndrome - virology | Simian Immunodeficiency Virus - genetics | HIV-1 - physiology | Time Factors | Simian Acquired Immunodeficiency Syndrome - genetics | Female | Simian Acquired Immunodeficiency Syndrome - transmission | Membrane Proteins - metabolism | Interleukin-8 - metabolism | Mucous Membrane - drug effects | CD4-Positive T-Lymphocytes - virology | Dendritic Cells - metabolism | Cervix Uteri - drug effects | Acute Disease | Cervix Uteri - virology | Mucous Membrane - virology | Cell Cycle Proteins - metabolism | Simian Immunodeficiency Virus - physiology | Simian Acquired Immunodeficiency Syndrome - prevention & control | Animals | Mucous Membrane - immunology | Body Fluids - metabolism | Cervix Uteri - immunology | Vagina - virology | Laurates - pharmacology | Simian Immunodeficiency Virus - drug effects | Virus diseases | Prevention | Glycerin | Causes of | Glycerol | Genetic aspects | Diagnosis | Research | Simian immunodeficiency virus | Health aspects | Immunization | Sample size | Binomial distribution | Statistical methods | Mathematical models | Laboratory animals | Gene expression | Cells
Journal Article