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1. Full Text Making a big thing of a small cell - recent advances in single cell analysis
by Galler, Kerstin and Bräutigam, Katharina and Große, Christina and Popp, Jürgen and Neugebauer, Ute
Analyst, ISSN 0003-2654, 2/2014, Volume 139, Issue 6, pp. 1237 - 1273
Single cell analysis is an emerging field requiring a high level interdisciplinary collaboration to provide detailed insights into the complex organisation,... 
SCANNING ELECTROCHEMICAL MICROSCOPY | ION CONDUCTANCE MICROSCOPY | ENHANCED RAMAN-SPECTROSCOPY | CHEMISTRY, ANALYTICAL | IONIZATION-MASS-SPECTROMETRY | ATOMIC-FORCE MICROSCOPY | CIRCULATING TUMOR-CELLS | RESONANCE ENERGY-TRANSFER | PROTEIN-PROTEIN INTERACTIONS | FLUORESCENCE CORRELATION SPECTROSCOPY | STRUCTURED-ILLUMINATION MICROSCOPY | Microfluidic Analytical Techniques - methods | Microscopy - methods | Computational Biology - methods | Humans | Microfluidic Analytical Techniques - instrumentation | Computational Biology - instrumentation | Magnetic Resonance Imaging - methods | Lab-On-A-Chip Devices | Neoplasms - diagnosis | Spectrum Analysis, Raman - methods | Single-Cell Analysis - instrumentation | Micromanipulation - methods | Optical Imaging - instrumentation | Animals | Magnetic Resonance Imaging - instrumentation | Mass Spectrometry - instrumentation | Micromanipulation - instrumentation | Microscopy - instrumentation | Single-Cell Analysis - methods | Spectrum Analysis, Raman - instrumentation | Mass Spectrometry - methods | Optical Imaging - methods
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2. Full Text Recent advances in combination of capillary electrophoresis with mass spectrometry: Methodology and theory
by Klepárník, Karel
ELECTROPHORESIS, ISSN 0173-0835, 01/2015, Volume 36, Issue 1, pp. 159 - 178
This review focuses on the latest development of microseparation electromigration methods in capillaries and microfluidic devices with MS detection and... 
Microfluidic devices | Capillary electrophoresis | Mass spectrometry | Electrospray | SHEATHLESS ELECTROSPRAY-IONIZATION | CHEMISTRY, ANALYTICAL | BIOCHEMICAL RESEARCH METHODS | MALDI-MS | SEPARATION TECHNIQUES | CONDUCTING LIQUID-FILM | CE-ICP-MS | AMINO-ACIDS | AMPLIFIED SAMPLE INJECTION | DRUG DEVELOPMENT | ZONE-ELECTROPHORESIS | FLOW NANOSPRAY INTERFACE | Microfluidic Analytical Techniques - methods | Food Analysis - methods | Humans | Microfluidic Analytical Techniques - instrumentation | Proteins - analysis | Electrophoresis, Capillary - instrumentation | Equipment Design | Metabolomics - methods | Polysaccharides - analysis | Single-Cell Analysis - instrumentation | Animals | Mass Spectrometry - instrumentation | Single-Cell Analysis - methods | Metabolomics - instrumentation | Electrophoresis, Capillary - methods | Food Analysis - instrumentation | Mass Spectrometry - methods | Electrophoresis | Analysis | Methods | Methodology | Capillarity | Forensic engineering | Ionization | Instrumentation | Devices | Microfluidics
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3. Full Text Seq-Well: Portable, low-cost rna sequencing of single cells at high throughput
by Gierahn, Todd M and Wadsworth, Marc H and Hughes, Travis K and Bryson, Bryan D and Butler, Andrew and Satija, Rahul and Fortune, Sarah and Christopher Love, J and Shalek, Alex K
Nature Methods, ISSN 1548-7091, 02/2017, Volume 14, Issue 4, pp. 395 - 398
Single-cell RNA-seq can precisely resolve cellular states, but applying this method to low-input samples is challenging. Here, we present Seq-Well, a portable,... 
HETEROGENEITY | IMMUNE | RESPONSES | EXPRESSION | BIOCHEMICAL RESEARCH METHODS | High-Throughput Nucleotide Sequencing - economics | Macrophages - physiology | Sequence Analysis, RNA - instrumentation | Single-Cell Analysis - economics | Humans | RNA, Messenger - genetics | Sequence Analysis, RNA - economics | Mycobacterium tuberculosis - pathogenicity | Sequence Analysis, RNA - methods | Single-Cell Analysis - instrumentation | Animals | Leukocytes, Mononuclear - physiology | Single-Cell Analysis - methods | HEK293 Cells | Mice | High-Throughput Nucleotide Sequencing - instrumentation | High-Throughput Nucleotide Sequencing - methods | 3T3 Cells | Macrophages - microbiology | Tuberculosis | Ribonucleic acids | Transcription | Low cost | Lysis | Macrophages | Beads | Gene sequencing
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4. Full Text Single-cell RNA-seq of rheumatoid arthritis synovial tissue using low-cost microfluidic instrumentation
by Stephenson, William and Donlin, Laura T and Butler, Andrew and Rozo, Cristina and Bracken, Bernadette and Rashidfarrokhi, Ali and Goodman, Susan M and Ivashkiv, Lionel B and Bykerk, Vivian P and Orange, Dana E and Darnell, Robert B and Swerdlow, Harold P and Satija, Rahul
Nature Communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 791 - 10
Droplet-based single-cell RNA-seq has emerged as a powerful technique for massively parallel cellular profiling. While this approach offers the exciting... 
TRANSCRIPTOMICS | FIBROBLAST-LIKE SYNOVIOCYTES | ACTIVATION | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GROWTH | CLASSIFICATION | STROMAL CELLS | EXPRESSION | CARTILAGE | Single-Cell Analysis - economics | Humans | Gene Expression Profiling | Synovial Membrane - metabolism | RNA - genetics | Arthritis, Rheumatoid - metabolism | Microfluidics - instrumentation | Single-Cell Analysis - instrumentation | Arthritis, Rheumatoid - genetics | Microfluidics - economics | Single-Cell Analysis - methods | Microfluidics - methods | Synovial Membrane - cytology | Fibroblasts - metabolism | RNA - metabolism | Subpopulations | Profiling | Instruments | Spatial discrimination | Control equipment | Instrumentation | Arthritis | Tissues | Gene expression | Ribonucleic acid--RNA | Synovium | Three dimensional printing | Rheumatoid arthritis | Low cost
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5. Full Text Single-cell barcoding and sequencing using droplet microfluidics
by Zilionis, R and Nainys, J and Veres, A and Savova, V and Zemmour, D and Klein, AM and Mazutis, L
NATURE PROTOCOLS, ISSN 1754-2189, 01/2017, Volume 12, Issue 1, pp. 44 - 73
Single-cell RNA sequencing has recently emerged as a powerful tool for mapping cellular heterogeneity in diseased and healthy tissues, yet high-throughput... 
HETEROGENEITY | STEM-CELLS | GENETIC-ANALYSIS | IMMUNE CELLS | CIRCULATING TUMOR-CELLS | RNA-SEQ | BIOCHEMICAL RESEARCH METHODS | ANTIBODY REPERTOIRE | MAMMALIAN-CELLS | EXPRESSION | FLOW | Sequence Analysis, RNA - instrumentation | Single-Cell Analysis - instrumentation | Lab-On-A-Chip Devices | High-Throughput Nucleotide Sequencing - instrumentation | Equipment Design | RNA sequencing | Innovations | Genetic research | Genetic transcription | Research | Microfluidics | Methods
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6. Full Text T-Probe: An Integrated Microscale Device for Online in Situ Single Cell Analysis and Metabolic Profiling Using Mass Spectrometry
by Liu, Renmeng and Pan, Ning and Zhu, Yanlin and Yang, Zhibo
Analytical Chemistry, ISSN 0003-2700, 09/2018, Volume 90, Issue 18, pp. 11078 - 11085
The exploration of single cells reveals cell heterogeneity and biological principle of cellular metabolism. Although a number of mass spectrometry (MS) based... 
CHEMISTRY, ANALYTICAL | MANIPULATION | EXTRACTION | DATABASE | ABLATION | CLASSIFICATION | LEUKEMIA | TISSUES | IONIZATION | CANCER | ACTIVE METABOLITE | Single-Cell Analysis - instrumentation | Tandem Mass Spectrometry - instrumentation | Drug Screening Assays, Antitumor - instrumentation | Humans | Metabolome | Metabolomics - instrumentation | HeLa Cells | Equipment Design
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7. Full Text High-throughput analysis and protein engineering using microcapillary arrays
by Chen, Bob and Lim, Sungwon and Kannan, Arvind and Alford, Spencer C and Sunden, Fanny and Herschlag, Daniel and Dimov, Ivan K and Baer, Thomas M and Cochran, Jennifer R
Nature Chemical Biology, ISSN 1552-4450, 02/2016, Volume 12, Issue 2, pp. 76 - 81
We describe a multipurpose technology platform, termed mu SCALE (microcapillary single-cell analysis and laser extraction), that enables massively parallel,... 
LIBRARIES | CELLS | HUMAN-ANTIBODIES | SINGLE-MOLECULE | YELLOW FLUORESCENT PROTEINS | ALKALINE-PHOSPHATASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SUPERFAMILY | YEAST SURFACE DISPLAY | DIRECTED EVOLUTION | CANCER | Protein Engineering - instrumentation | Fluorescent Dyes - chemistry | Fungal Proteins - analysis | Single-Cell Analysis - instrumentation | Flow Cytometry | Gene Library | Chemistry Techniques, Analytical - instrumentation | Protein Binding | Biosensing Techniques - instrumentation | Protein Array Analysis - instrumentation | Bacterial Proteins - analysis | Cellular biology | Scientific method | Proteomics
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8. Full Text Raman-activated cell sorting based on dielectrophoretic single-cell trap and release
by Zhang, Peiran and Ren, Lihui and Zhang, Xu and Shan, Yufei and Wang, Yun and Ji, Yuetong and Yin, Huabing and Huang, Wei E and Xu, Jian and Ma, Bo
Analytical Chemistry, ISSN 0003-2700, 02/2015, Volume 87, Issue 4, pp. 2282 - 2289
Raman-activated cell sorting (RACS) is a promising single-cell technology that holds several significant advantages, as RACS is label-free, information-rich,... 
CHEMISTRY, ANALYTICAL | MANIPULATION | SPECTROSCOPY | TWEEZERS | IDENTIFICATION | FLOW | PATHOGENS | Saccharomyces cerevisiae - cytology | Single-Cell Analysis - instrumentation | Cell Separation - instrumentation | Cells, Cultured | Microfluidic Analytical Techniques - instrumentation | Software | Spectrum Analysis, Raman - instrumentation
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9. Full Text Single-cell systems biology by super-resolution imaging and combinatorial labeling
by Lubeck, Eric and Cai, Long
Nature Methods, ISSN 1548-7091, 07/2012, Volume 9, Issue 7, pp. 743 - 748
Fluorescence microscopy is a powerful quantitative tool for exploring regulatory networks in single cells. However, the number of molecular species that can be... 
YEAST | LOCALIZATION | PROTEIN | MOLECULE | BIOCHEMICAL RESEARCH METHODS | GENE-EXPRESSION | TIME | OPTICAL RECONSTRUCTION MICROSCOPY | IN-SITU | PROBES | Saccharomyces cerevisiae - genetics | RNA, Messenger - genetics | In Situ Hybridization, Fluorescence | Gene Expression Profiling | Image Processing, Computer-Assisted - methods | Microscopy, Fluorescence - instrumentation | Single-Cell Analysis - instrumentation | Systems Biology - methods | Systems Biology - instrumentation | Microscopy, Fluorescence - methods | Single-Cell Analysis - methods | Image Processing, Computer-Assisted - instrumentation | Fluorescent Dyes | Usage | Systems biology | Physiological aspects | Genetic aspects | Research | Brewer's yeast | Fluorescence microscopy | Combinatorics | Cells | Image processing systems
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