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Alcoholism: Clinical and Experimental Research, ISSN 0145-6008, 06/2019, Volume 43, Issue 6, pp. 1180 - 1190
Background Alcohol alters synaptic transmission in the brain. The N-methyl-D-aspartate (NMDA) receptor (NMDAR), a subtype of glutamate-gated ion channel, is an... 
Alcohol Sensitivity | Desensitization | Ion Channel Gating | methyl‐D‐aspartate Receptor | SINGLE-CHANNEL | GLYCINE | ACID | SUBSTANCE ABUSE | ETHANOL INHIBITION | HETEROMERIC NMDA RECEPTORS | SITES | MEMBRANE-ASSOCIATED DOMAIN | RAT-BRAIN | MUTATIONS | N-methyl-D-aspartate Receptor | EXPRESSION | Glutamate | Amino acids
Journal Article
Journal of General Physiology, ISSN 0022-1295, 02/2018, Volume 150, Issue 2, pp. 323 - 668
Journal Article
Nature Neuroscience, ISSN 1097-6256, 09/2009, Volume 12, Issue 9, pp. 1114 - 1120
Journal Article
Neuropharmacology, ISSN 0028-3908, 03/2018, Volume 131, pp. 453 - 474
GABA receptor is the primary mediator of inhibition in the adult mammalian brain. Our recent studies revealed that a classic gating scheme for GABA R needed to... 
Single-channel recordings | Kinetic model | Intermediate states | GABAA receptor | Spontaneous activity | γ-aminobutyric acid | receptor | GABA | Index Medicus
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 06/2014, Volume 81, pp. 101 - 115
The alpha7 nicotinic acetylcholine receptor (nAChR) has some peculiar kinetic properties. From the literature of alpha 7 nAChR-mediated currents we concluded... 
SINGLE-CHANNEL | POSITIVE ALLOSTERIC MODULATOR | ACTIVATION | DESENSITIZATION | PNU-120596 | SYNAPTIC-TRANSMISSION | NEUROSCIENCES | SOLUTION EXCHANGE | RAT HIPPOCAMPAL-NEURONS | alpha 7 nicotinic acetylcholine receptor | Kinetic modeling | Choline | PHARMACOLOGY & PHARMACY | CENTRAL-NERVOUS-SYSTEM | ION CHANNELS | EXPRESSION
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 03/2018, Volume 131, pp. 453 - 474
GABA(A) receptor is the primary mediator of inhibition in the adult mammalian brain. Our recent studies revealed that a classic gating scheme for GABA(A)R... 
RAT | MECHANISM | DESENSITIZATION | gamma-aminobutyric acid | CURRENTS | AGONIST-BINDING | NEUROSCIENCES | ACETYLCHOLINE-RECEPTOR CHANNELS | GLYCINE RECEPTORS | Single-channel recordings | Kinetic model | GABA(A) receptor | AFFINITY | NEURONS | PHARMACOLOGY & PHARMACY | Intermediate states | Spontaneous activity
Journal Article
NEUROPHARMACOLOGY, ISSN 0028-3908, 12/2008, Volume 55, Issue 7, pp. 1212 - 1218
Homomeric P2X receptors differ in their electrophysiological and pharmacological profiles. The rapidly activating and desensitizing P2X(3) receptors are known... 
RECOVERY | Desensitization | Pain | SINGLE-CHANNEL PROPERTIES | ECTODOMAIN | PHARMACOLOGY & PHARMACY | Purinergic | DRG neurons | IDENTIFICATION | NEUROSCIENCES | DEPENDENCE | AGONIST
Journal Article
Methods in Molecular Biology, ISSN 1064-3745, 2014, Volume 1183, pp. 371 - 399
Single-channel recording provides high resolution information on gating mechanisms of ion channels that are generally difficult to obtain from macroscopic... 
Idealization | Segmental k-means | Single channel | Ion channel | Dwell-time | Global fitting | Missed events | Kinetics | Maximum likelihood | Hidden Markov modeling | Duration histogram | Gating | Single molecule | Likelihood Functions | Markov Chains | Animals | Ion Channels - metabolism | Models, Biological | Computer Simulation | Humans | Software | Ion Channel Gating | Index Medicus
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