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eLife, ISSN 2050-084X, 2014, Volume 3
Journal Article
EMBO Molecular Medicine, ISSN 1757-4676, 03/2013, Volume 5, Issue 3, pp. 344 - 352
Sirtuins are NAD‐dependent protein deacetylases known to have protective effects against age‐related diseases such as cancer, diabetes, cardiovascular and... 
neurodegeneration | Parkinson's disease | aging | Alzheimer's disease | sirtuins | Sirtuins | Aging | Neurodegeneration | MEDICINE, RESEARCH & EXPERIMENTAL | LIFE-SPAN | OXIDATIVE STRESS | WALLERIAN DEGENERATION | ALPHA-SYNUCLEIN | DIETARY RESTRICTION | AXONAL DEGENERATION | CAENORHABDITIS-ELEGANS | CALORIC RESTRICTION | STEM-CELL HOMEOSTASIS | HUNTINGTONS-DISEASE | Sirtuin 1 - metabolism | Neurons - pathology | Neurodegenerative Diseases - pathology | Enzyme Activators - therapeutic use | Humans | Neurodegenerative Diseases - genetics | Molecular Targeted Therapy | Neurodegenerative Diseases - drug therapy | Neurogenesis | Sirtuin 1 - genetics | Sirtuin 2 - metabolism | Sirtuin 2 - genetics | Animals | Neurons - enzymology | Sirtuin 2 - antagonists & inhibitors | Histone Deacetylase Inhibitors - therapeutic use | Enzyme Activation | Nerve Degeneration | Neurons - drug effects | Neurodegenerative Diseases - enzymology | Nervous system diseases | Amyloid beta-protein | Huntingtons disease | Phosphorylation | Transcription factors | Peptides | Ribosomal DNA | Parkinsons disease | Biosynthesis | Proteins | Older people | Cell cycle | Localization | Movement disorders | Enzymes | Nutrient deficiency | Neurodegenerative diseases | Diabetes mellitus | Huntington's disease | Mammals | Fatty acids | SIRT1 protein | NAD | Life span | Mutation | Alzheimers disease | Binding sites | Dementia | Reviews
Journal Article
Tumor Biology, ISSN 1010-4283, 6/2013, Volume 34, Issue 3, pp. 1847 - 1854
Head and neck squamous cell carcinoma (HNSCC) include a group of malignant neoplasms that arise from the upper aerodigestive tract and represent the seventh... 
Biomedicine | SIRT genes | Real-time quantitative reverse transcription-polymerase chain reaction | Cancer Research | Head and neck squamous cell carcinoma | Circadian clock genes | Sirtuin | SURVIVAL | Head and necksquamous cell carcinoma | DEACETYLASE | RISK | HUMAN-PAPILLOMAVIRUS | METABOLISM | ONCOLOGY | OROPHARYNGEAL CANCER | TUMOR-SUPPRESSOR | PREDICTIVE FACTORS | EPIDEMIOLOGY | Sirtuin 1 - metabolism | Prognosis | Sirtuin 3 - metabolism | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Sirtuin 1 - genetics | Immunoenzyme Techniques | Sirtuin 2 - metabolism | Carcinoma, Squamous Cell - mortality | Aged, 80 and over | Biomarkers, Tumor - metabolism | Adult | Female | Sirtuins - genetics | Real-Time Polymerase Chain Reaction | Sirtuin 3 - genetics | RNA, Messenger - genetics | Survival Rate | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Head and Neck Neoplasms - pathology | Sirtuin 2 - genetics | Head and Neck Neoplasms - genetics | Aged | Biomarkers, Tumor - genetics | Head and Neck Neoplasms - mortality | Neoplasm Staging | Sirtuins - metabolism | Medical colleges | Squamous cell carcinoma | Genes | Resveratrol | Genetic research | Development and progression | Genetic aspects | Genetic transcription | Health aspects | Cancer | Polymerase chain reaction | Gene expression | Head & neck cancer
Journal Article
Tumor Biology, ISSN 1010-4283, 8/2015, Volume 36, Issue 8, pp. 6159 - 6171
Journal Article
Journal Article
Journal Article
Journal Article
Clinical Science, ISSN 0143-5221, 02/2013, Volume 124, Issue 3, pp. 153 - 164
Sirtuins are members of the Sir2 (silent information regulator 2) family, a group of class III deacetylases. Mammals have seven different sirtuins,... 
SIRT1 (sirtuin 1) | Aging | Diabetic nephropathy | Sirtuin | MEDICINE, RESEARCH & EXPERIMENTAL | HYPOXIA-INDUCIBLE FACTOR | LIFE-SPAN | LIPID-METABOLISM | B-DEPENDENT TRANSCRIPTION | SIRT1 DEACETYLASE | CELL-SURVIVAL | SIRT1(sirtuin 1) | sirtuin | STRESS-RESPONSIVE DEACETYLASE | GENE-EXPRESSION | aging | CHRONIC KIDNEY-DISEASE | diabetic nephropathy | CALORIE RESTRICTION | Sirtuin 1 - metabolism | Animals | Sirtuin 3 - metabolism | Caloric Restriction | Diabetic Nephropathies - metabolism | Humans | Sirtuins - metabolism | Aging - metabolism | Kidney Diseases - metabolism | Atg, autophagy-related gene | Idh2, isocitrate dehydrogenase 2 | WFR, Wistar fatty diabetic rat | adenovirus E1V 19-kDa interacting protein 3 | PGC-1α, PPAR-γ co-activator-1α | LC3, light chain 3 | PTP1B, protein tyrosine phosphatase 1B | TNF-α, tumour necrosis factor α | ICAM-1, intercellular adhesion molecule 1 | IGF, insulin-like growth factor | mTOR, mammalian target of rapamycin | CKD, chronic kidney disease | RAS, renin–angiotensin system | FOXO, forkhead box O | H3K9, histone H3 Lys9 | eNOS, endothelial NO synthase | PER2, Period 2 | PPAR, peroxisome-proliferator-activated receptor | HIF, hypoxia-inducible factor | UUO, unilateral ureteral obstruction | Mn-SOD, manganese superoxide dismutase | Bnip3, BCL2 | LXR, liver X receptor | CRP, C-reactive protein | AGE, advanced glycation end-product | PARP, poly(ADP-ribose) polymerase | IRS, insulin receptor substrate | CR, calorie restriction | AMPK, AMP-activated protein kinase | Review | VCAM-1, vascular cell adhesion protein 1 | SREBP, sterol-regulatory-element-binding protein | BMAL1, brain and muscle ARNT (aryl hydrocarbon receptor nuclear translocator)-like 1 | TGF, transforming growth factor | ROS, reactive oxygen species | AT1R, angiotensin type 1 receptor | SIRT1 etc., sirtuin 1 etc., SNP, single nucleotide polymorphism | H3K9me3, H3K9 trimethylation |