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Cell Metabolism, ISSN 1550-4131, 09/2013, Volume 18, Issue 3, pp. 416 - 430
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2004, Volume 279, Issue 26, pp. 26830 - 26838
Mutations in Sir Antagonist 1 ( SAN1 ) suppress defects in SIR4 and SPT16 in Saccharomyces cerevisiae . San1 contains a RING domain, suggesting that it... 
MATING-TYPE LOCI | YEAST | TRANSCRIPTIONAL STATES | CHROMATIN-STRUCTURE | SHUTTLE VECTORS | HISTONE H2B | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | SILENCING PROTEINS | CELL-CYCLE | SACCHAROMYCES-CEREVISIAE | Saccharomyces cerevisiae - genetics | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Silent Information Regulator Proteins, Saccharomyces cerevisiae - genetics | Minichromosome Maintenance Complex Component 4 | DNA-Binding Proteins - metabolism | Saccharomyces cerevisiae - metabolism | Sirtuin 2 | Sirtuins - chemistry | Triticum - enzymology | Sirtuins - genetics | DNA, Ribosomal - genetics | Telomere - genetics | Protein Structure, Tertiary | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Histone Deacetylases - genetics | Silent Information Regulator Proteins, Saccharomyces cerevisiae - chemistry | Silent Information Regulator Proteins, Saccharomyces cerevisiae - metabolism | Cell Cycle Proteins - metabolism | Gene Silencing | Histone Deacetylases - chemistry | Ubiquitin - chemistry | Ubiquitin-Protein Ligases - metabolism | Recombinant Proteins - chemistry | Histone Deacetylases - metabolism | Recombinant Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Ubiquitin-Protein Ligases - chemistry | Saccharomyces cerevisiae - cytology | Saccharomyces cerevisiae Proteins - metabolism | Ubiquitin-Protein Ligases - genetics | Sirtuins - metabolism | Saccharomyces cerevisiae Proteins - chemistry | Index Medicus
Journal Article
Human Molecular Genetics, ISSN 0964-6906, 06/2014, Volume 23, Issue 11, pp. 2995 - 3007
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 10/2010, Volume 30, Issue 20, pp. 4890 - 4900
Journal Article
Nature Neuroscience, ISSN 1097-6256, 08/2013, Volume 16, Issue 8, pp. 1008 - 1015
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 08/2015, Volume 59, Issue 8, pp. 1443 - 1457
ScopeResveratrol (RSV), a natural polyphenol, has been reported to attenuate nonalcoholic fatty liver disease (NAFLD); however, its underlying mechanism is... 
NAFLD | Treatment | Hepatocyte | SIRT1 | Resveratrol | ACTIVATION | LIPID-METABOLISM | PROTEIN-KINASE | FOOD SCIENCE & TECHNOLOGY | NONALCOHOLIC FATTY LIVER | DIET | INFLAMMATION | DISEASE | AMPK | HEALTH | Sirtuin 1 - metabolism | Non-alcoholic Fatty Liver Disease - pathology | Liver - pathology | Stilbenes - therapeutic use | Antioxidants - metabolism | Humans | Stilbenes - metabolism | Mice, 129 Strain | Sirtuin 1 - genetics | Autophagy - drug effects | Fatty Acids, Nonesterified - metabolism | Liver - drug effects | RNA Interference | Enzyme Induction - drug effects | Sirtuin 1 - chemistry | Cyclic AMP - metabolism | Fatty Acids, Nonesterified - adverse effects | Microscopy, Electron, Transmission | Second Messenger Systems - drug effects | Liver - ultrastructure | Liver - metabolism | Enzyme Inhibitors - pharmacology | Non-alcoholic Fatty Liver Disease - metabolism | Adenylyl Cyclases - metabolism | Sirtuin 1 - antagonists & inhibitors | Hep G2 Cells | Cyclic AMP - antagonists & inhibitors | Antioxidants - therapeutic use | Animals | Adenylyl Cyclases - chemistry | Lipid Metabolism - drug effects | Fatty Acids, Nonesterified - antagonists & inhibitors | Cyclic AMP - agonists | Non-alcoholic Fatty Liver Disease - diet therapy | Adenylyl Cyclases - genetics | Dietary Supplements | Triglycerides | Liver diseases | Fatty acids | Liver | Index Medicus
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 02/2016, Volume 101, pp. 100 - 111
The thiazolidinedione pioglitazone, which is also a PPAR-γ agonist, now is widely used in patients with hypercholesterolemia and hypertriglyceridemia. NF-κB is... 
NF-κB p65 acetylation | Acute kidney injury | Cisplatin | PPAR-γ | PHOSPHORYLATION | P300 | PPAR-gamma | PROTECTS | ISCHEMIA-REPERFUSION INJURY | INHIBITION | INFLAMMATION | NF-kappa B p65 acetylation | AMPK | PHARMACOLOGY & PHARMACY | ACCUMULATION | DYSFUNCTION | EXPRESSION | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Kidney - pathology | Transcription Factor RelA - antagonists & inhibitors | E1A-Associated p300 Protein - genetics | Male | E1A-Associated p300 Protein - metabolism | Protein Transport - drug effects | Protective Agents - therapeutic use | PPAR gamma - metabolism | Thiazolidinediones - administration & dosage | Sirtuin 1 - genetics | Dose-Response Relationship, Drug | Kidney - metabolism | Thiazolidinediones - therapeutic use | Protein Processing, Post-Translational - drug effects | Antineoplastic Agents - adverse effects | E1A-Associated p300 Protein - antagonists & inhibitors | Acute Kidney Injury - chemically induced | Cisplatin - antagonists & inhibitors | Phosphorylation - drug effects | Kidney - drug effects | Acute Kidney Injury - pathology | AMP-Activated Protein Kinases - antagonists & inhibitors | Mice, Inbred C57BL | Antineoplastic Agents - chemistry | Sirtuin 1 - antagonists & inhibitors | Acute Kidney Injury - prevention & control | Gene Expression Regulation - drug effects | Acetylation - drug effects | Animals | Signal Transduction - drug effects | Transcription Factor RelA - metabolism | PPAR gamma - agonists | Survival Analysis | Cisplatin - adverse effects | Protective Agents - administration & dosage | Acute Kidney Injury - metabolism | AMP-Activated Protein Kinases - genetics | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 01/2015, Volume 125, Issue 4, pp. 710 - 719
The precise mechanism for reduced thrombosis in prekallikrein null mice (Klkb1(-/-)) is unknown. Klkb1(-/-) mice have delayed carotid artery occlusion times on... 
PLASMA KALLIKREIN | MOLECULAR-WEIGHT KININOGEN | ENDOTHELIAL-CELLS | IN-VIVO | NITRIC-OXIDE | FACTOR EXPRESSION | VASCULAR-PERMEABILITY | DEFICIENT MICE | CONTACT ACTIVATION | HEMATOLOGY | FACTOR-XII | Epoprostenol - genetics | Receptor, Bradykinin B2 - genetics | Receptors, G-Protein-Coupled - metabolism | Epoprostenol - biosynthesis | Peptide Fragments - pharmacology | Carotid Artery Thrombosis - metabolism | Pyrones - pharmacology | Sirtuin 1 - genetics | Thromboplastin - antagonists & inhibitors | Nerve Tissue Proteins - biosynthesis | Synaptotagmins - biosynthesis | Carotid Artery Thrombosis - chemically induced | Prekallikrein | Thromboplastin - biosynthesis | Proto-Oncogene Proteins - metabolism | Kruppel-Like Transcription Factors - biosynthesis | Proto-Oncogene Proteins - antagonists & inhibitors | Angiotensin II - pharmacology | Receptor, Bradykinin B2 - biosynthesis | Sirtuin 1 - biosynthesis | Proto-Oncogene Proteins - genetics | Imidazoles - pharmacology | Angiotensin II - analogs & derivatives | Sulfonamides - pharmacology | Nerve Tissue Proteins - genetics | Sirtuin 1 - antagonists & inhibitors | Mice, Knockout | Naphthalenes - pharmacology | Animals | Partial Thromboplastin Time | Thromboplastin - genetics | Receptors, G-Protein-Coupled - antagonists & inhibitors | Mice | Receptors, G-Protein-Coupled - genetics | Synaptotagmins - genetics | Carotid Artery Thrombosis - genetics | Carotid Artery Thrombosis - pathology | Kruppel-Like Transcription Factors - antagonists & inhibitors | Kruppel-Like Transcription Factors - genetics | RNA, Messenger | Index Medicus | Abridged Index Medicus | Thrombosis and Hemostasis
Journal Article
The Journal of Nutritional Biochemistry, ISSN 0955-2863, 09/2012, Volume 23, Issue 9, pp. 1100 - 1112
Resveratrol is a natural polyphenolic compound with anti-inflammatory, antioxidant and neuroprotective properties, and it serves as a chemopreventive and... 
Silent information regulator 1 | AMP-activated protein kinase α | Protein kinase B | Survivin | Resveratrol | Apoptosis | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Inhibitor of Apoptosis Proteins - genetics | Stilbenes - pharmacology | Membrane Potential, Mitochondrial - drug effects | Sirtuin 1 - genetics | Chromatin Assembly and Disassembly - drug effects | Repressor Proteins - antagonists & inhibitors | Adipocytes, White - ultrastructure | Adipocytes, White - drug effects | Caspases - metabolism | Inhibitor of Apoptosis Proteins - antagonists & inhibitors | Inhibitor of Apoptosis Proteins - metabolism | Caspases - chemistry | Proto-Oncogene Proteins c-akt - metabolism | Repressor Proteins - metabolism | Second Messenger Systems - drug effects | AMP-Activated Protein Kinases - antagonists & inhibitors | Gene Silencing | Repressor Proteins - genetics | Antioxidants - pharmacology | 3T3-L1 Cells | Down-Regulation - drug effects | Sirtuin 1 - antagonists & inhibitors | Up-Regulation - drug effects | Animals | Mice | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | S Phase - drug effects | AMP-Activated Protein Kinases - genetics | Adipocytes, White - metabolism | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Antioxidants | Cytochrome c | RNA | Adenylic acid | Cells | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 01/2015, Volume 34, Issue 2, pp. 188 - 198
Journal Article