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FEBS Journal, ISSN 1742-464X, 10/2015, Volume 282, Issue 20, pp. 3971 - 3985
Recent studies have highlighted the involvement of metadherin ( MTDH ), an oncogenic protein, in promoting cancer progression, metastasis and chemoresistance... 
tumour promotion and progression | AMPK | breast cancer | metadherin | SIRT | SIRT1 | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Cell Adhesion Molecules - agonists | Cell Adhesion Molecules - genetics | Humans | Cell Adhesion Molecules - antagonists & inhibitors | Glycogen Synthase Kinase 3 beta | Neoplasm Proteins - antagonists & inhibitors | Neoplasm Proteins - metabolism | Triple Negative Breast Neoplasms - drug therapy | Sirtuin 1 - genetics | Breast Neoplasms - metabolism | Breast Neoplasms - enzymology | Adenocarcinoma - metabolism | Protein Processing, Post-Translational - drug effects | RNA Interference | Carcinoma - enzymology | Female | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - drug effects | Phosphorylation - drug effects | Neoplasm Proteins - genetics | Sirtuin 1 - chemistry | Triple Negative Breast Neoplasms - enzymology | Carcinoma - drug therapy | Cell Survival - drug effects | Glycogen Synthase Kinase 3 - chemistry | Glycogen Synthase Kinase 3 - antagonists & inhibitors | AMP-Activated Protein Kinases - antagonists & inhibitors | Adenocarcinoma - enzymology | Enzyme Inhibitors - pharmacology | Enzyme Activation - drug effects | Glycogen Synthase Kinase 3 - metabolism | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Cell Adhesion Molecules - metabolism | Sirtuin 1 - antagonists & inhibitors | AMP-Activated Protein Kinases - chemistry | Hypoglycemic Agents - pharmacology | Neoplasm Proteins - agonists | Triple Negative Breast Neoplasms - metabolism | Cell Line, Tumor | Cell Proliferation - drug effects | Carcinoma - metabolism | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 07/2017, Volume 292, Issue 28, pp. 11970 - 11979
An imbalance between oxidative stress and antioxidant activity plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD).... 
pathogenesis | antioxidant | cigarette smoke extract | sirtuin 1 (SIRT1) | chronic obstructive pulmonary disease (COPD) | neutrophil elastase | BIOCHEMISTRY & MOLECULAR BIOLOGY | oxidative stress | heme oxygenase 1 | Heme Oxygenase-1 - chemistry | Leukocyte Elastase - metabolism | Sirtuin 1 - metabolism | Smoking - adverse effects | Heme Oxygenase-1 - metabolism | NF-E2-Related Factor 2 - antagonists & inhibitors | Respiratory Mucosa - drug effects | Oxidative Stress | Humans | NF-E2-Related Factor 2 - agonists | Tobacco Products - analysis | Pulmonary Disease, Chronic Obstructive - pathology | Bronchi - immunology | Sirtuin 1 - genetics | Recombinant Fusion Proteins | Bronchi - drug effects | Respiratory Mucosa - pathology | Proteolysis | Respiratory Mucosa - immunology | Bronchi - metabolism | Smoke - analysis | Active Transport, Cell Nucleus | Pulmonary Disease, Chronic Obstructive - metabolism | Complex Mixtures - toxicity | Sirtuin 1 - chemistry | Bronchi - pathology | Biomarkers - metabolism | Recombinant Proteins - metabolism | Cell Line | Tobacco Products - adverse effects | Smoke - adverse effects | Cells, Cultured | Recombinant Proteins - chemistry | Heme Oxygenase-1 - antagonists & inhibitors | Sirtuin 1 - antagonists & inhibitors | Protein Transport | Gene Expression Regulation, Enzymologic | Smoking - metabolism | NF-E2-Related Factor 2 - metabolism | Smoking - pathology | Respiratory Mucosa - metabolism | Index Medicus | Signal Transduction
Journal Article
Biological Psychiatry, ISSN 0006-3223, 2016, Volume 80, Issue 11, pp. 815 - 826
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 07/2010, Volume 299, Issue 1, pp. 110 - 116
Endothelial progenitor cells (EPCs) play an important role in angiogenesis, which is essential for numerous physiological processes as well as tumor growth.... 
PHYSIOLOGY | EMERGING ROLES | MIR-34A | GROWTH ARREST | ENDOCRINOLOGY & METABOLISM | DOWN-REGULATION | PHENOTYPE | DYSFUNCTION | SIRT1 | EXPRESSION | CANCER | CALORIE RESTRICTION | RNA, Small Interfering - genetics | Antigens, CD34 - analysis | Nerve Tissue Proteins - analysis | Male | Forkhead Transcription Factors - physiology | Stem Cells - cytology | RNA - genetics | Antigens, CD - analysis | Vascular Endothelial Growth Factor Receptor-2 - physiology | Endothelial Cells - physiology | Nerve Tissue Proteins - physiology | Vascular Endothelial Growth Factor Receptor-2 - analysis | Peptides - physiology | Gene Expression Regulation | Cellular Senescence - physiology | Rats | RNA - chemistry | Reverse Transcriptase Polymerase Chain Reaction | AC133 Antigen | Glycoproteins - physiology | Rats, Sprague-Dawley | Sirtuin 1 - antagonists & inhibitors | Blotting, Western | Antigens, CD34 - physiology | Neovascularization, Physiologic - physiology | Animals | Endothelial Cells - cytology | Sirtuin 1 - physiology | Forkhead Transcription Factors - analysis | Antigens, CD - physiology | Stem Cells - physiology | MicroRNAs - genetics | Glycoproteins - analysis | MicroRNAs - physiology | RNA, Small Interfering - administration & dosage | Peptides - analysis | Genetic aspects | Cell physiology | MicroRNA | Neovascularization | Properties | Endothelium | Mitochondria | Rodents | Cell cycle | Bone marrow | Ribonucleic acid--RNA | Cells | Apoptosis | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 10/2008, Volume 295, Issue 4, pp. 833 - 842
Alcoholic fatty liver is associated with inhibition of sirtuin 1 (SIRT1) and AMP-activated kinase (AMPK), two critical signaling molecules regulating the... 
Sirtuin 1 | Alcoholic liver steatosis | Acetylation | Lipid metabolism | Peroxisome proliferator-activated receptor γ coactivator α | AMP-activated kinase | Sterol regulatory element-binding protein 1c | sirtuin 1 | DIETARY SATURATED FAT | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | LIPID-METABOLISM | alcoholic liver steatosis | lipid metabolism | MITOCHONDRIAL-FUNCTION | ENDOPLASMIC-RETICULUM STRESS | peroxisome proliferator-activated receptor gamma coactivator alpha | acetylation | sterol regulatory element-binding protein 1c | MAMMALIAN SIRTUIN-1 | TRANSCRIPTION FACTOR FOXO1 | INDUCED OXIDATIVE STRESS | ADIPONECTIN SECRETION | GASTROENTEROLOGY & HEPATOLOGY | CALORIE RESTRICTION | Up-Regulation | Ethanol - toxicity | Stilbenes - therapeutic use | Mice, Inbred C57BL | Receptors, Adiponectin - metabolism | Male | Sirtuins - biosynthesis | Animals | Adenylate Kinase - metabolism | Fatty Liver, Alcoholic - drug therapy | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Sterol Regulatory Element Binding Protein 1 - antagonists & inhibitors | Adiponectin - metabolism | Trans-Activators - metabolism | Mice | Transcription Factors | Oxidative Stress - drug effects | Sterol Regulatory Element Binding Protein 1 - metabolism | Studies | Signal transduction | Molecules | Liver diseases | Rodents | Kinases | Fatty acids | Cells | Index Medicus | Liver and Biliary Tract | peroxisome proliferator-activated receptor γ coactivator α
Journal Article
Molecular Nutrition & Food Research, ISSN 1613-4125, 10/2014, Volume 58, Issue 10, pp. 1941 - 1951
Scope: Oxidized LDL (oxLDL) induced vascular endothelial cell injury is a key event in the pathogenesis of atherosclerosis (AS). In our previous studies, we... 
Autophagy | Injury | Delphinidin‐3‐glucoside | Endothelial cells | Atherosclerosis | Delphinidin-3-glucoside | INDUCED APOPTOSIS | NITRIC-OXIDE SYNTHASE | FOOD SCIENCE & TECHNOLOGY | BIOAVAILABILITY | DELPHINIDIN | IN-VITRO | ANTHOCYANIN-RICH EXTRACT | INFLAMMATION | DYSFUNCTION | E-DEFICIENT MICE | Endothelium, Vascular - cytology | Sirtuin 1 - metabolism | AMP-Activated Protein Kinases - metabolism | Phosphorylation | Human Umbilical Vein Endothelial Cells - metabolism | Antioxidants - metabolism | Humans | Sirtuin 1 - genetics | Endothelium, Vascular - ultrastructure | RNA Interference | Human Umbilical Vein Endothelial Cells - cytology | Sirtuin 1 - chemistry | Human Umbilical Vein Endothelial Cells - ultrastructure | Microscopy, Electron, Transmission | Atherosclerosis - pathology | Lipoproteins, LDL - adverse effects | Signal Transduction | Cell Survival | AMP-Activated Protein Kinases - antagonists & inhibitors | Cells, Cultured | Anthocyanins - metabolism | Glucosides - metabolism | Sirtuin 1 - antagonists & inhibitors | AMP-Activated Protein Kinases - chemistry | Atherosclerosis - metabolism | Lipoproteins, LDL - antagonists & inhibitors | Endothelium, Vascular - metabolism | Endothelium, Vascular - pathology | Protein Processing, Post-Translational | RNA, Small Interfering | Dietary Supplements | AMP-Activated Protein Kinases - genetics | Atherosclerosis - prevention & control | Apoptosis | Anthocyanin | Low density lipoproteins | Endothelium | Index Medicus
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 11/2017, Volume 43, Issue 3, pp. 1025 - 1036
Background/Aims: Resveratrol is a polyphenol enriched in the skins of grapes and berries, that shows various beneficial effects for human health. In the... 
Original Paper | SAPK/JNK | Osteoblast | Akt | EGF | Migration | Resveratrol | CELLS | PHYSIOLOGY | KINASE | CANCER | PROSTAGLANDIN-E2 | FAMILY | CELL BIOLOGY | CYCLIC-AMP | IN-VITRO | SAPK/JNK Akt | PATHWAY | BONE | DIFFERENTIATION | Sirtuin 1 - metabolism | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | JNK Mitogen-Activated Protein Kinases - metabolism | Stilbenes - pharmacology | Heterocyclic Compounds, 4 or More Rings - pharmacology | rho-Associated Kinases - antagonists & inhibitors | rho-Associated Kinases - metabolism | Flavonoids - pharmacology | p38 Mitogen-Activated Protein Kinases - metabolism | Osteoblasts - cytology | Phosphorylation - drug effects | JNK Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Osteoblasts - drug effects | Cells, Cultured | Imidazoles - pharmacology | Sirtuin 1 - antagonists & inhibitors | Anthracenes - pharmacology | Cell Movement - drug effects | Animals | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice | Pyridines - pharmacology | Epidermal Growth Factor - pharmacology | Osteoblasts - metabolism | Mitogen-Activated Protein Kinase 1 - metabolism | Immunoglobulins | Fractures | Epidermal growth factor | Metabolism | Kinases | Cell adhesion & migration | Index Medicus
Journal Article
Journal Article