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by Cai, Na and Bigdeli, Tim B and Kretzschmar, Warren and Lei, Yihan and Liang, Jieqin and Song, Li and Hu, Jingchu and Li, Qibin and Jin, Wei and Hu, Zhenfei and Wang, Guangbiao and Wang, Linmao and Qian, Puyi and Liu, Yuan and Jiang, Tao and Lu, Yao and Zhang, Xiuqing and Yin, Ye and Lie, Yingrui and Xu, Xun and Gao, Jingfang and Reimers, Mark and Webb, Todd and Riley, Brien and Bacanu, Silviu and Peterson, Roseann E and Chen, Yiping and Zhong, Hui and Liu, Zhengrong and Wang, Gang and Sun, Jing and Sang, Hong and Jiang, Guoqing and Zhou, Xiaoyan and Li, Yi and Zhang, Wei and Wang, Xueyi and Fang, Xiang and Pan, Runde and Miao, Guodong and Zhang, Qiwen and Hu, Jian and Yu, Fengyu and Du, Bo and Sang, Wenhua and Li, Keqing and Chen, Guibing and Cai, Min and Yang, Lijun and Yang, Donglin and Ha, Baowei and Hong, Xiaohong and Deng, Hong and Li, Gongying and Li, Kan and Song, Yan and Gao, Shugui and Zhang, Jinbei and Gan, Zhaoyu and Meng, Huaqing and Pan, Jiyang and Gao, Chengge and Zhang, Kerang and Sun, Ning and Li, Youhui and Niu, Qihui and Zhang, Yutang and Liu, Tieqiao and Hu, Chunmei and Zhang, Zhen and Lv, Luxian and Dong, Jicheng and Wang, Xiaoping and Tao, Ming and Wang, Xumei and Xia, Jing and Rong, Han and He, Qiang and Liu, Tiebang and Huang, Guoping and Mei, Qiyi and Shen, Zhenming and Liu, Ying and Shen, Jianhua and Tian, Tian and Liu, Xiaojuan and Wu, Wenyuan and Gu, Danhua and Fu, Guangyi and Shi, Jianguo and Chen, Yunchun and Gan, Xiangchao and Liu, Lanfen and Wang, Lina and Yang, Fuzhong and Cong, Enzhao and Marchini, Jonathan and Yang, Huanming and Wang, Jian and Shi, Shenxun and ... and CONVERGE Consortium and CONVERGE consortium
Nature, ISSN 0028-0836, 07/2015, Volume 523, Issue 7562, pp. 588 - 591
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2013, Volume 18, Issue 3, pp. 416 - 430
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2012, Volume 15, Issue 5, pp. 665 - 674
Nonalcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular and liver-related mortality. NAFLD is characterized by both triglyceride... 
RAT-LIVER | RISK-FACTORS | MACROPHAGE APOPTOSIS | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | HMG-COA REDUCTASE | STEATOHEPATITIS | 3-HYDROXY-3-METHYLGLUTARYL COENZYME | PREVALENCE | MICRORNA EXPRESSION | MODULATION | CELL BIOLOGY | Sirtuin 1 - metabolism | Up-Regulation | Cholesterol - blood | Humans | Middle Aged | Sterol Esterase - metabolism | Male | MicroRNAs - metabolism | Desmosterol - metabolism | Cardiovascular Diseases - genetics | Cholesterol - genetics | Sirtuin 1 - genetics | Case-Control Studies | Phosphorylation - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Adenylate Kinase - metabolism | Non-alcoholic Fatty Liver Disease | Sterol O-Acyltransferase - metabolism | Adult | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Gene Expression | Fatty Liver - metabolism | Cardiovascular Diseases - metabolism | Fatty Liver - blood | Liver - metabolism | Receptors, LDL - metabolism | Cholesterol - metabolism | Cholesterol, LDL - genetics | Phenotype | Sterol Esterase - genetics | Desmosterol - blood | Cholesterol, LDL - metabolism | MicroRNAs - genetics | Sterol O-Acyltransferase - genetics | Adenylate Kinase - genetics | Hydroxymethylglutaryl CoA Reductases - genetics | Enzymes | Liver diseases | Low density lipoproteins | Genes | Esters | Triglycerides | Cholesterol | MicroRNA | Fatty liver | Blood cholesterol | Physiological aspects | Hydrolases | Blood lipids | Health aspects | Statins | Index Medicus | atherosclerosis | Nonalcoholic steatohepatitis | cholesterol | Nonalcoholic fatty liver disease | fatty liver | lipogenesis | hypercholesterolemia | HMG CoA reductase
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2009, Volume 106, Issue 47, pp. 19975 - 19979
Journal Article
by Xiong, H and Ni, Z and He, J and Jiang, S and Li, X and He, J and Gong, W and Zheng, L and Chen, S and Li, B and Zhang, N and Lyu, X and Huang, G and Chen, B and Zhang, Y and He, F
Oncogene, ISSN 0950-9232, 06/2017, Volume 36, Issue 25, pp. 3528 - 3540
Considerable evidences have shown that autophagy has an important role in tumor chemoresistance. However, it is still unknown whether the lncRNA HULC (highly... 
ACTIVATION | USP22 | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PROLIFERATION | CANCER | CELL BIOLOGY | MAINTENANCE | LONG NONCODING RNA | ONCOLOGY | GENETICS & HEREDITY | CHEMORESISTANCE | SUPPRESSES | CONTRIBUTES | Sirtuin 1 - metabolism | Humans | Drug Resistance, Neoplasm | MicroRNAs - metabolism | Neoplasm Proteins - metabolism | Autophagy | RNA, Neoplasm - metabolism | Sirtuin 1 - genetics | Carcinoma, Hepatocellular - drug therapy | Carcinoma, Hepatocellular - genetics | Antineoplastic Agents - pharmacology | Enzyme Stability - genetics | Gene Expression Regulation, Neoplastic - drug effects | 3' Untranslated Regions | Neoplasm Proteins - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | RNA, Long Noncoding - genetics | Hep G2 Cells | Liver Neoplasms - metabolism | RNA, Neoplasm - genetics | MicroRNAs - genetics | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | RNA, Long Noncoding - metabolism | Carcinoma, Hepatocellular - metabolism | Autophagy (Cytology) | Care and treatment | RNA | Development and progression | Genetic aspects | Hepatoma | Gene expression | Health aspects | Ubiquitin | Peptidase | 5-Fluorouracil | MiRNA | Chemoresistance | Hepatocellular carcinoma | mRNA | SIRT1 protein | Proteins | Liver cancer | Chemotherapy | Oxaliplatin | Phagocytosis | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2012, Volume 109, Issue 39, pp. 15888 - 15893
The epidemics of insulin resistance (IR) and type 2 diabetes (T2D) affect the first world as well as less-developed countries, and now affect children as well.... 
Receptors | 3T3 L1 cells | Myasthenia gravis | Diet | Insulin resistance | Mice | Adipocytes | Type 2 diabetes mellitus | Diabetes | Insulin | Aging | Glycotoxins | Obesity | LIFE-SPAN | OXIDATIVE STRESS | METABOLIC SYNDROME | OXIDANT STRESS | MULTIDISCIPLINARY SCIENCES | DOWN-REGULATION | RISK-FACTOR | glycotoxins | MESANGIAL CELLS | aging | INFLAMMATORY RESPONSE | END-PRODUCTS | obesity | METHYLGLYOXAL | Sirtuin 1 - metabolism | Deoxyglucose - metabolism | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Experimental - genetics | Metabolic Syndrome - metabolism | Diabetes Mellitus, Type 2 - metabolism | Insulin Receptor Substrate Proteins - metabolism | Metabolic Syndrome - chemically induced | Sirtuin 1 - genetics | Inflammation - drug therapy | Glycation End Products, Advanced - adverse effects | Diabetes Mellitus, Experimental - metabolism | Insulin Receptor Substrate Proteins - genetics | Receptor for Advanced Glycation End Products | Macrophages - pathology | Administration, Oral | Oxidative Stress - genetics | 3T3-L1 Cells | Adipocytes - pathology | Proto-Oncogene Proteins c-akt | Macrophages - metabolism | Animals | Glycation End Products, Advanced - pharmacology | Metabolic Syndrome - genetics | Adipocytes - metabolism | Deoxyglucose - genetics | Diabetes Mellitus, Experimental - pathology | Inflammation - genetics | Diabetes Mellitus, Type 2 - pathology | Metabolic Syndrome - pathology | Oxidative Stress - drug effects | Receptors, Immunologic - genetics | Receptors, Immunologic - metabolism | Type 2 diabetes | Antioxidants | Cell receptors | Physiological aspects | Glycosylation | Properties | Proteins | Oxidative stress | Genotype & phenotype | Epidemics | Index Medicus | Biological Sciences
Journal Article
BBA - Molecular Basis of Disease, ISSN 0925-4439, 07/2014, Volume 1842, Issue 7, pp. 902 - 915
Journal Article
The Journal of Cell Biology, ISSN 0021-9525, 12/2010, Volume 191, Issue 7, pp. 1299 - 1313
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2014, Volume 34, Issue 6, pp. 1100 - 1120
Journal Article
Aging Cell, ISSN 1474-9718, 08/2017, Volume 16, Issue 4, pp. 837 - 846
Kallistatin, an endogenous protein, protects against vascular injury by inhibiting oxidative stress and inflammation in hypertensive rats and enhancing the... 
34a | sirtuin 1 | RNA | micro | kallistatin | vascular senescence | aging | oxidative stress | microRNA-34a | NECROSIS-FACTOR-ALPHA | TISSUE KALLIKREIN INHIBITOR | BINDING PROTEIN | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | ORGAN INJURY | CAENORHABDITIS-ELEGANS | PROTECTIVE ROLE | PROGENITOR-CELL SENESCENCE | ENDOTHELIAL-CELLS | RENAL INJURY | Sirtuin 1 - metabolism | Diabetes Mellitus, Experimental - drug therapy | Endothelial Progenitor Cells - cytology | MicroRNAs - antagonists & inhibitors | Streptozocin | Humans | Diabetes Mellitus, Experimental - genetics | NADPH Oxidases - metabolism | Caenorhabditis elegans Proteins - metabolism | Cellular Senescence - drug effects | Male | MicroRNAs - metabolism | Sirtuin 1 - genetics | Telomerase - genetics | Plasminogen Activator Inhibitor 1 - metabolism | Superoxides - metabolism | beta-Galactosidase - metabolism | NADPH Oxidases - genetics | Telomerase - metabolism | Diabetes Mellitus, Experimental - chemically induced | Superoxides - antagonists & inhibitors | Nitric Oxide Synthase Type III - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Diabetes Mellitus, Experimental - metabolism | Sirtuins - genetics | Endothelial Progenitor Cells - metabolism | Cellular Senescence - genetics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Catalase - genetics | Endothelial Progenitor Cells - drug effects | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Nitric Oxide Synthase Type III - genetics | Serpins - pharmacology | Catalase - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Animals | Caenorhabditis elegans - drug effects | Genistein - pharmacology | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Mice | MicroRNAs - genetics | beta-Galactosidase - genetics | Caenorhabditis elegans Proteins - genetics | Sirtuins - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Gene expression | MicroRNA | Oxidative stress</