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Journal Article
by Cai, Na and Bigdeli, Tim B and Kretzschmar, Warren and Lei, Yihan and Liang, Jieqin and Song, Li and Hu, Jingchu and Li, Qibin and Jin, Wei and Hu, Zhenfei and Wang, Guangbiao and Wang, Linmao and Qian, Puyi and Liu, Yuan and Jiang, Tao and Lu, Yao and Zhang, Xiuqing and Yin, Ye and Lie, Yingrui and Xu, Xun and Gao, Jingfang and Reimers, Mark and Webb, Todd and Riley, Brien and Bacanu, Silviu and Peterson, Roseann E and Chen, Yiping and Zhong, Hui and Liu, Zhengrong and Wang, Gang and Sun, Jing and Sang, Hong and Jiang, Guoqing and Zhou, Xiaoyan and Li, Yi and Zhang, Wei and Wang, Xueyi and Fang, Xiang and Pan, Runde and Miao, Guodong and Zhang, Qiwen and Hu, Jian and Yu, Fengyu and Du, Bo and Sang, Wenhua and Li, Keqing and Chen, Guibing and Cai, Min and Yang, Lijun and Yang, Donglin and Ha, Baowei and Hong, Xiaohong and Deng, Hong and Li, Gongying and Li, Kan and Song, Yan and Gao, Shugui and Zhang, Jinbei and Gan, Zhaoyu and Meng, Huaqing and Pan, Jiyang and Gao, Chengge and Zhang, Kerang and Sun, Ning and Li, Youhui and Niu, Qihui and Zhang, Yutang and Liu, Tieqiao and Hu, Chunmei and Zhang, Zhen and Lv, Luxian and Dong, Jicheng and Wang, Xiaoping and Tao, Ming and Wang, Xumei and Xia, Jing and Rong, Han and He, Qiang and Liu, Tiebang and Huang, Guoping and Mei, Qiyi and Shen, Zhenming and Liu, Ying and Shen, Jianhua and Tian, Tian and Liu, Xiaojuan and Wu, Wenyuan and Gu, Danhua and Fu, Guangyi and Shi, Jianguo and Chen, Yunchun and Gan, Xiangchao and Liu, Lanfen and Wang, Lina and Yang, Fuzhong and Cong, Enzhao and Marchini, Jonathan and Yang, Huanming and Wang, Jian and Shi, Shenxun and ... and CONVERGE consortium and CONVERGE Consortium
Nature (London), ISSN 1476-4687, 2015, Volume 523, Issue 7562, pp. 588 - 591
Journal Article
Biochimica et biophysica acta. Molecular and cell biology of lipids, ISSN 1388-1981, 07/2016, Volume 1861, Issue 7, pp. 584 - 593
We have previously shown that high fat (HF) feeding during pregnancy primes the development of non-alcoholic steatohepatits (NASH) in the adult offspring.... 
Development | Aging | Fatty liver | High fat | Circadian | Maternal diet | DE-NOVO | REV-ERB | NUCLEAR RECEPTORS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL BIOLOGY | LIPOTOXICITY | NONALCOHOLIC FATTY LIVER | DEACETYLASE SIRT3 | BIOPHYSICS | CIRCADIAN-CLOCK | METABOLISM | DISEASE | MICE | Sirtuin 1 - metabolism | Liver - pathology | Sirtuin 3 - metabolism | Diet, High-Fat - adverse effects | Non-alcoholic Fatty Liver Disease - etiology | CLOCK Proteins - genetics | Sirtuin 1 - genetics | Nuclear Receptor Subfamily 1, Group F, Member 1 - metabolism | CLOCK Proteins - metabolism | Female | Lipid Metabolism - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - metabolism | Repressor Proteins - metabolism | Sterol Regulatory Element Binding Protein 1 - metabolism | Disease Models, Animal | Sirtuin 3 - genetics | Nuclear Receptor Subfamily 1, Group D, Member 1 - genetics | Non-alcoholic Fatty Liver Disease - genetics | Oxidation-Reduction | Signal Transduction | Liver - metabolism | Mice, Inbred C57BL | Circadian Rhythm - genetics | Gene Expression Regulation | Repressor Proteins - genetics | Non-alcoholic Fatty Liver Disease - metabolism | Photoperiod | Receptors, Cytoplasmic and Nuclear - genetics | Non-alcoholic Fatty Liver Disease - physiopathology | Prenatal Exposure Delayed Effects - physiopathology | Prenatal Exposure Delayed Effects - metabolism | Pregnancy | Prenatal Exposure Delayed Effects - genetics | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Mice | Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics | Receptors, Cytoplasmic and Nuclear - metabolism | Gene expression | Physiological aspects | Genetic transcription | DNA binding proteins | Genes | Liver
Journal Article
Cell metabolism, ISSN 1550-4131, 2012, Volume 15, Issue 5, pp. 665 - 674
Nonalcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular and liver-related mortality. NAFLD is characterized by both triglyceride... 
RAT-LIVER | RISK-FACTORS | MACROPHAGE APOPTOSIS | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | HMG-COA REDUCTASE | STEATOHEPATITIS | 3-HYDROXY-3-METHYLGLUTARYL COENZYME | PREVALENCE | MICRORNA EXPRESSION | MODULATION | CELL BIOLOGY | Sirtuin 1 - metabolism | Up-Regulation | Cholesterol - blood | Humans | Middle Aged | Sterol Esterase - metabolism | Male | MicroRNAs - metabolism | Desmosterol - metabolism | Cardiovascular Diseases - genetics | Cholesterol - genetics | Sirtuin 1 - genetics | Case-Control Studies | Phosphorylation - genetics | Hydroxymethylglutaryl CoA Reductases - metabolism | Adenylate Kinase - metabolism | Non-alcoholic Fatty Liver Disease | Sterol O-Acyltransferase - metabolism | Adult | Female | Lipid Metabolism - genetics | Sterol Regulatory Element Binding Protein 2 - genetics | Sterol Regulatory Element Binding Protein 2 - metabolism | Fatty Liver - genetics | Receptors, LDL - genetics | Gene Expression | Fatty Liver - metabolism | Cardiovascular Diseases - metabolism | Fatty Liver - blood | Liver - metabolism | Receptors, LDL - metabolism | Cholesterol - metabolism | Cholesterol, LDL - genetics | Phenotype | Sterol Esterase - genetics | Desmosterol - blood | Cholesterol, LDL - metabolism | MicroRNAs - genetics | Sterol O-Acyltransferase - genetics | Adenylate Kinase - genetics | Hydroxymethylglutaryl CoA Reductases - genetics | Enzymes | Liver diseases | Low density lipoproteins | Genes | Esters | Triglycerides | Cholesterol | MicroRNA | Fatty liver | Blood cholesterol | Physiological aspects | Hydrolases | Blood lipids | Health aspects | Statins | atherosclerosis | Nonalcoholic steatohepatitis | cholesterol | Nonalcoholic fatty liver disease | fatty liver | lipogenesis | hypercholesterolemia | HMG CoA reductase
Journal Article
Aging cell, ISSN 1474-9718, 2017, Volume 16, Issue 4, pp. 837 - 846
...‐1 expression, and elevated telomerase activity. Kallistatin blocked TNF‐α‐induced superoxide levels, NADPH oxidase activity, and microRNA‐21 (miR‐21... 
sirtuin 1 | kallistatin | vascular senescence | aging | microRNA‐34a | oxidative stress | microRNA-34a | TISSUE KALLIKREIN INHIBITOR | MICRORNA-21 | SIRT1 | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | PROTECTIVE ROLE | INFLAMMATION | PROGENITOR-CELL SENESCENCE | ENDOTHELIAL-CELLS | BINDING-SITE | RENAL INJURY | Sirtuin 1 - metabolism | Diabetes Mellitus, Experimental - drug therapy | Endothelial Progenitor Cells - cytology | MicroRNAs - antagonists & inhibitors | Streptozocin | Humans | Diabetes Mellitus, Experimental - genetics | NADPH Oxidases - metabolism | Caenorhabditis elegans Proteins - metabolism | Cellular Senescence - drug effects | Male | MicroRNAs - metabolism | Sirtuin 1 - genetics | Telomerase - genetics | Plasminogen Activator Inhibitor 1 - metabolism | Superoxides - metabolism | beta-Galactosidase - metabolism | NADPH Oxidases - genetics | Telomerase - metabolism | Diabetes Mellitus, Experimental - chemically induced | Superoxides - antagonists & inhibitors | Nitric Oxide Synthase Type III - metabolism | Plasminogen Activator Inhibitor 1 - genetics | Diabetes Mellitus, Experimental - metabolism | Sirtuins - genetics | Endothelial Progenitor Cells - metabolism | Cellular Senescence - genetics | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Catalase - genetics | Endothelial Progenitor Cells - drug effects | Cells, Cultured | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Nitric Oxide Synthase Type III - genetics | Serpins - pharmacology | Catalase - metabolism | Tumor Necrosis Factor-alpha - pharmacology | Animals | Caenorhabditis elegans - drug effects | Genistein - pharmacology | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Mice | MicroRNAs - genetics | beta-Galactosidase - genetics | Caenorhabditis elegans Proteins - genetics | Sirtuins - metabolism | Tumor Necrosis Factor-alpha - antagonists & inhibitors | Gene expression | MicroRNA | Oxidative stress | Senescence | Genistein | INK4a protein | Kinases | NAD(P)H oxidase | Catalase | Rodents | Aging | Aorta | miRNA | Telomerase | Protein-tyrosine kinase | Tyrosine | Enzymes | Diabetes mellitus | p16 Protein | Superoxide | SIRT1 protein | Life span | Tumor necrosis factor | MicroRNAs | Stem cells | Nematodes | Diabetes | Original
Journal Article
Diabetes (New York, N.Y.), ISSN 1939-327X, 2016, Volume 65, Issue 3, pp. 610 - 618
...) inflammasome controls the activation of caspase-1, and the release of proinflammatory cytokines interleukin (IL)-1 and IL-18... 
ACTIVATION | ADIPOCYTES | METABOLISM | ADIPONECTIN | CERAMIDE CONTENT | ENDOCRINOLOGY & METABOLISM | SENSITIVITY | NLRP3 INFLAMMASOME | HEPATIC STEATOSIS | EXPRESSION | INDUCED INSULIN-RESISTANCE | Fatty Acid Synthase, Type I - genetics | Sirtuin 1 - metabolism | Glucose Transporter Type 4 - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Obesity - immunology | Humans | Leptin - metabolism | Caspase 1 - metabolism | Male | Gene Expression Profiling | Interleukin-1beta - genetics | PPAR gamma - metabolism | Sirtuin 1 - genetics | Acetyl-CoA Carboxylase - genetics | Subcutaneous Fat - immunology | Subcutaneous Fat - metabolism | Lipogenesis - genetics | Interleukin-1beta - metabolism | Adiponectin - genetics | Adiponectin - metabolism | Female | Adipogenesis - genetics | Child | Lipoprotein Lipase - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | PPAR gamma - genetics | Glucose Transporter Type 4 - genetics | Inflammasomes | Lipoprotein Lipase - genetics | Down-Regulation | Insulin Resistance | Toll-Like Receptor 4 - genetics | Intra-Abdominal Fat - metabolism | Fatty Acid Synthase, Type I - metabolism | Subcutaneous Fat - pathology | Toll-Like Receptor 4 - metabolism | Abdomen | Obesity - metabolism | Carrier Proteins - genetics | Magnetic Resonance Imaging | Sterol Regulatory Element Binding Protein 1 - genetics | Caspase 1 - genetics | Adolescent | Intra-Abdominal Fat - pathology | Acetyl-CoA Carboxylase - metabolism | Adipose tissues | Overweight persons | Care and treatment | Inflammation | Research | Health aspects | Metabolism
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2009, Volume 106, Issue 47, pp. 19975 - 19979
Journal Article
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 03/2014, Volume 34, Issue 6, pp. 1100 - 1120
Journal Article