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BBA - Molecular and Cell Biology of Lipids, ISSN 1388-1981, 09/2016, Volume 1861, Issue 9, pp. 1180 - 1191
Expression of ATP-binding cassette transporter G1 (ABCG1), a molecule facilitating cholesterol efflux to HDL, is activated by liver X receptor (LXR). In this... 
RCT | MEK1/2 | SIRT1 | ABCG1 | Atherosclerosis | LXR | ATHEROSCLEROTIC LESION DEVELOPMENT | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DENSITY-LIPOPROTEINS | LXR-ALPHA | CELL BIOLOGY | RECEPTOR-DEFICIENT MICE | REACTIVE PROTEIN EXPRESSION | SCAVENGER RECEPTOR | EFFLUX | BIOPHYSICS | LIVER | GENE-TRANSCRIPTION | Atherosclerosis - genetics | Humans | Aorta - metabolism | Cholesterol - genetics | Foam Cells - drug effects | Nitriles - administration & dosage | Flavonoids - administration & dosage | Biological Transport - drug effects | Biological Transport - genetics | Foam Cells - metabolism | Liver X Receptors - biosynthesis | MAP Kinase Kinase 1 - antagonists & inhibitors | Promoter Regions, Genetic | Atherosclerosis - drug therapy | Sirtuin 1 - biosynthesis | MAP Kinase Kinase 1 - metabolism | Cholesterol - metabolism | Atherosclerosis - metabolism | Mice, Knockout | Retinoid X Receptor alpha - agonists | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | MAP Kinase Signaling System - drug effects | Apolipoproteins E - genetics | Butadienes - administration & dosage | Retinoid X Receptor alpha - genetics | Macrophages - drug effects | Mice | ATP Binding Cassette Transporter, Sub-Family G, Member 1 - biosynthesis | ATP Binding Cassette Transporter, Sub-Family G, Member 1 - genetics | Liver X Receptors - genetics | Macrophages | Cholesterol | RNA
Journal Article
Science, ISSN 0036-8075, 7/2007, Volume 317, Issue 5837, pp. 516 - 519
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2015, Volume 10, Issue 4, pp. e0124670 - e0124670
Background Sirtuin 1 (SIRT1) and sirtuin 2 (SIRT2) are NAD+-dependent protein deacetylases involved in the regulation of key cancer-associated genes. In this... 
BREAST-CANCER | REGULATES SIRT1 | BRONCHIAL EPITHELIAL-CELLS | DEACETYLASE | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | GROWTH | SENESCENCE | DEPENDENT PATHWAY | CARCINOMA | P53 | Sirtuin 1 - metabolism | RNA, Small Interfering - genetics | Prognosis | Lung Neoplasms - mortality | Humans | Middle Aged | Lung Neoplasms - pathology | Male | Thiourea - pharmacology | Sirtuin 1 - genetics | Sirtuin 2 - metabolism | Neoplasm Grading | RNA Interference | Female | Sirtuin 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Carcinoma, Non-Small-Cell Lung - pathology | Lung Neoplasms - genetics | Acetanilides - pharmacology | Gene Expression | Carcinoma, Non-Small-Cell Lung - genetics | Tumor Suppressor Protein p53 - metabolism | Carcinoma, Non-Small-Cell Lung - mortality | Sirtuin 1 - antagonists & inhibitors | Sirtuin 2 - genetics | Cell Line, Tumor | Aged | Cell Proliferation - drug effects | Neoplasm Staging | Thiourea - analogs & derivatives | Proteins | Squamous cell carcinoma | Lung cancer, Small cell | Genetic aspects | Lung cancer, Non-small cell | Cancer | Sirtuins | Cell proliferation | Biotechnology | Epithelial cells | Gene regulation | Lung | Lung cancer | Kinases | Cell growth | Non-small cell lung carcinoma | siRNA | Tumor cell lines | Gene expression | Patients | Survival | SIRT1 protein | NAD | Pathology | Cell lines | Apoptosis | Tumors | Index Medicus
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 02/2016, Volume 55, Issue 6, pp. 2252 - 2256
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 06/2018, Volume 373, Issue 1748, pp. 20170083 - 20170083
Sirtuins are NAD(+)-dependent protein deacylases capable of cleaving off acetyl as well as other acyl groups from the e-amino group of lysines in histones and... 
NAD | Sirtuins | Epigenetics | Sirt2 | Deacetylases | Assays | RESVERATROL | SUPPRESSOR | ACTIVATION | ASSAY | ACETYLATION | sirtuins | KINASE | deacetylases | assays | epigenetics | DISCOVERY | POTENT | HISTONE DEACETYLASES | BIOLOGY | NAD(+) | SELECTIVITY | NAD - chemistry | Fluorescence | Molecular Docking Simulation | Humans | Sirtuin 2 - chemistry | Fluorescence polarization | Peptides | Assaying | Substrates | Modulators | Proteins | Inhibitors | Lysine | Histones | Docking | Deacylation | Chemical synthesis | Binding sites | Index Medicus | 15 | 1001
Journal Article
Journal Article
Nature, ISSN 0028-0836, 11/2007, Volume 450, Issue 7170, pp. 712 - 716
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 03/2007, Volume 27, Issue 10, pp. 2606 - 2616
Journal Article
Neuroscience, ISSN 0306-4522, 2009, Volume 159, Issue 3, pp. 993 - 1002
Journal Article