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1. Full Text Sirtuin 1 and sirtuin 3: Physiological modulators of metabolism
by Nogueiras, Ruben and Habegger, Kirk M and Chaudhary, Nilika and Finan, Brian and Banks, Alexander S and Dietrich, Marcelo O and Horvath, Tamas L and Sinclair, David A and Pfluger, Paul T and Tschöp, Matthias H
Physiological reviews, ISSN 0031-9333, 07/2012, Volume 92, Issue 3, pp. 1479 - 1514
Life Sciences & Biomedicine | Physiology | Science & Technology | Enzyme Activators - pharmacology | Sirtuin 1 - metabolism | Genetic Predisposition to Disease | Sirtuin 3 - genetics | Sirtuin 3 - metabolism | Humans | Homeostasis | Models, Molecular | Metabolic Diseases - drug therapy | Signal Transduction - genetics | Structure-Activity Relationship | Circadian Rhythm | Sirtuin 1 - genetics | Polymorphism, Genetic | Phenotype | Animals | Metabolic Diseases - metabolism | Signal Transduction - drug effects | Metabolic Diseases - genetics | Protein Conformation | Enzyme Activation | Energy Metabolism - genetics | Energy Metabolism - drug effects | Enzymes | Cell metabolism | Causes of | Metabolic diseases | NAD (Coenzyme) | Regulation | Research | Health aspects | Proteins | Mitochondria | Bioenergetics | Metabolism | Index Medicus
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2. Full Text Apelin gene therapy increases myocardial vascular density and ameliorates diabetic cardiomyopathy via upregulation of sirtuin 3
by Zeng, Heng and He, Xiaochen and Hou, Xuwei and Li, Lanfang and Chen, Jian-Xiong
American journal of physiology. Heart and circulatory physiology, ISSN 0363-6135, 02/2014, Volume 306, Issue 4, pp. H585 - H597
VEGF/VEGFR2 | Diabetic cardiomyopathy | Angiogenesis | Sirtuin 3 | Ang-1/Tie-2 | Apelin | Cardiac & Cardiovascular Systems | Physiology | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Diabetic Cardiomyopathies - metabolism | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Male | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiopoietin-2 - metabolism | Diabetic Cardiomyopathies - physiopathology | Receptors, Vascular Endothelial Growth Factor - metabolism | Myocardium - metabolism | Neovascularization, Pathologic - physiopathology | Receptor, TIE-2 - metabolism | Diabetic Cardiomyopathies - therapy | Receptors, Vascular Endothelial Growth Factor - genetics | Neovascularization, Pathologic - therapy | Heart - physiopathology | Sirtuin 3 - genetics | Endothelium, Vascular - physiopathology | Intercellular Signaling Peptides and Proteins - genetics | Up-Regulation - genetics | Adipokines | Receptor, TIE-2 - genetics | Diabetic Cardiomyopathies - genetics | Angiopoietin-1 - genetics | Animals | Endothelium, Vascular - metabolism | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Apoptosis - physiology | Prevention | Cardiomyopathy | Physiological aspects | Genetic research | Genetic aspects | Research | Diabetes | Gene therapy | Heart diseases | Heart failure | Rodents | Glucose | Apoptosis | Index Medicus | VEGFR2 | apelin | Tie-2 | sirtuin 3 | VEGF | angiogenesis | Ang-1 | diabetic cardiomyopathy | Integrative Cardiovascular Physiology and Pathophysiology
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3. Full Text Irisin modulates genes associated with severe coronavirus disease (COVID-19) outcome in human subcutaneous adipocytes cell culture
by de Oliveira, Miriane and De Sibio, Maria Teresa and Mathias, Lucas Solla and Rodrigues, Bruna Moretto and Sakalem, Marna Eliana and Nogueira, Célia Regina
Molecular and cellular endocrinology, ISSN 0303-7207, 09/2020, Volume 515, pp. 110917 - 110917
Irisin | ADAM10 | SARS-CoV-2 | TRIB3 | FURIN | Adipose tissue | Endocrinology & Metabolism | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Amyloid Precursor Protein Secretases - genetics | Humans | ADAM10 Protein - metabolism | Adipocytes - drug effects | COVID-19 | Histone Acetyltransferases - metabolism | Peptidyl-Dipeptidase A - metabolism | Gene Ontology | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Histone Deacetylase 2 - genetics | Fibronectins - pharmacology | Signal Transduction | rab1 GTP-Binding Proteins - metabolism | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | Repressor Proteins - genetics | Betacoronavirus - metabolism | Toll-Like Receptor 3 - metabolism | Angiotensin-Converting Enzyme 2 | Amyloid Precursor Protein Secretases - metabolism | Coronavirus Infections - virology | Models, Biological | Betacoronavirus - genetics | Jumonji Domain-Containing Histone Demethylases - metabolism | Sirtuin 1 - metabolism | Pandemics | ADAM10 Protein - genetics | Histone Acetyltransferases - genetics | Adipocytes - cytology | Sirtuin 1 - genetics | Peptidyl-Dipeptidase A - genetics | Furin - genetics | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Membrane Proteins - metabolism | Toll-Like Receptor 3 - genetics | Nuclear Proteins - genetics | Furin - metabolism | Obesity - virology | Molecular Sequence Annotation | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Nuclear Proteins - metabolism | Jumonji Domain-Containing Histone Demethylases - genetics | Fibronectins - metabolism | rab1 GTP-Binding Proteins - genetics | Gene Expression Regulation - drug effects | Adipocytes - metabolism | Fibronectins - genetics | Histone Deacetylase 2 - metabolism | Pneumonia, Viral - virology | Virus diseases | Enzymes | Anopheles | Genes | Genetic aspects | Coronaviruses | Health aspects | Cells | Risk factors | Index Medicus
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4. Full Text LncRNA HULC triggers autophagy via stabilizing Sirt1 and attenuates the chemosensitivity of HCC cells
by Xiong, H and Ni, Z and He, J and Jiang, S and Li, X and He, J and Gong, W and Zheng, L and Chen, S and Li, B and Zhang, N and Lyu, X and Huang, G and Chen, B and Zhang, Y and He, F
Oncogene, ISSN 0950-9232, 06/2017, Volume 36, Issue 25, pp. 3528 - 3540
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Sirtuin 1 - metabolism | Humans | Drug Resistance, Neoplasm | MicroRNAs - metabolism | Neoplasm Proteins - metabolism | Autophagy | RNA, Neoplasm - metabolism | Sirtuin 1 - genetics | Carcinoma, Hepatocellular - drug therapy | Carcinoma, Hepatocellular - genetics | Antineoplastic Agents - pharmacology | Enzyme Stability - genetics | Gene Expression Regulation, Neoplastic - drug effects | 3' Untranslated Regions | Neoplasm Proteins - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | RNA, Long Noncoding - genetics | Hep G2 Cells | Liver Neoplasms - metabolism | RNA, Neoplasm - genetics | MicroRNAs - genetics | Thiolester Hydrolases - genetics | Thiolester Hydrolases - metabolism | RNA, Long Noncoding - metabolism | Carcinoma, Hepatocellular - metabolism | Autophagy (Cytology) | Care and treatment | RNA | Development and progression | Genetic aspects | Hepatoma | Gene expression | Health aspects | Ubiquitin | Peptidase | 5-Fluorouracil | Chemoresistance | Hepatocellular carcinoma | mRNA | SIRT1 protein | Proteins | Liver cancer | Chemotherapy | Oxaliplatin | miRNA | Phagocytosis | Index Medicus
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5. Full Text SIRT3 restricts hepatitis B virus transcription and replication through epigenetic regulation of covalently closed circular DNA involving suppressor of variegation 3‐9 homolog 1 and SET domain containing 1A histone methyltransferases
by Ren, Ji‐Hua and Hu, Jie‐Li and Cheng, Sheng‐Tao and Yu, Hai‐Bo and Wong, Vincent Kam Wai and Law, Betty Yuen Kwan and Yang, Yong‐Feng and Huang, Ying and Liu, Yi and Chen, Wei‐Xian and Cai, Xue‐Fei and Tang, Hua and Hu, Yuan and Zhang, Wen‐Lu and Liu, Xiang and Long, Quan‐Xin and Zhou, Li and Tao, Na‐Na and Zhou, Hong‐Zhong and Yang, Qiu‐Xia and Ren, Fang and He, Lin and Gong, Rui and Huang, Ai‐Long and Chen, Juan
Hepatology (Baltimore, Md.), ISSN 0270-9139, 10/2018, Volume 68, Issue 4, pp. 1260 - 1276
Gastroenterology & Hepatology | Life Sciences & Biomedicine | Science & Technology | Sirtuin 3 - genetics | Hepatitis B - genetics | Virus Replication - genetics | Humans | DNA, Complementary - genetics | Real-Time Polymerase Chain Reaction - methods | Hepatitis B - physiopathology | Epigenesis, Genetic - genetics | Sensitivity and Specificity | Hepatitis B virus - genetics | Histone Methyltransferases - metabolism | DNA, Viral - genetics | PR-SET Domains - genetics | Index Medicus
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6. Full Text A role of the inflammasome in the low storage capacity of the abdominal subcutaneous adipose tissue in obese adolescents
by Kursawe, Romy and Dixit, Vishwa D and Scherer, Philipp E and Santoro, Nicola and Narayan, Deepak and Gordillo, Ruth and Giannini, Cosimo and Lopez, Ximena and Pierpont, Bridget and Nouws, Jessica and Shulman, Gerald I and Caprio, Sonia
Diabetes (New York, N.Y.), ISSN 0012-1797, 03/2016, Volume 65, Issue 3, pp. 610 - 618
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fatty Acid Synthase, Type I - genetics | Sirtuin 1 - metabolism | Glucose Transporter Type 4 - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Obesity - immunology | Humans | Leptin - metabolism | Caspase 1 - metabolism | Male | Gene Expression Profiling | Interleukin-1beta - genetics | PPAR gamma - metabolism | Sirtuin 1 - genetics | Acetyl-CoA Carboxylase - genetics | Subcutaneous Fat - immunology | Subcutaneous Fat - metabolism | Lipogenesis - genetics | Interleukin-1beta - metabolism | Adiponectin - genetics | Adiponectin - metabolism | Female | Adipogenesis - genetics | Child | Lipoprotein Lipase - metabolism | Carrier Proteins - immunology | Macrophages - immunology | Sterol Regulatory Element Binding Protein 1 - metabolism | PPAR gamma - genetics | Glucose Transporter Type 4 - genetics | Inflammasomes | Lipoprotein Lipase - genetics | Down-Regulation | Insulin Resistance | Toll-Like Receptor 4 - genetics | Intra-Abdominal Fat - metabolism | Fatty Acid Synthase, Type I - metabolism | Subcutaneous Fat - pathology | Toll-Like Receptor 4 - metabolism | Abdomen | Obesity - metabolism | Carrier Proteins - genetics | Magnetic Resonance Imaging | Sterol Regulatory Element Binding Protein 1 - genetics | Caspase 1 - genetics | Adolescent | Intra-Abdominal Fat - pathology | Acetyl-CoA Carboxylase - metabolism | Adipose tissues | Overweight persons | Care and treatment | Inflammation | Research | Health aspects | Insulin resistance | Nuclear magnetic resonance--NMR | Diabetes | Cytokines | Tissues | Index Medicus | Abridged Index Medicus | Metabolism
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7. Full Text Disruption of the Ang II type 1 receptor promotes longevity in mice
by Benigni, Ariela and Corna, Daniela and Zoja, Carla and Sonzogni, Aurelio and Latini, Roberto and Salio, Monica and Conti, Sara and Rottoli, Daniela and Longaretti, Lorena and Cassis, Paola and Morigi, Marina and Coffman, Thomas M and Remuzzi, Giuseppe
The Journal of clinical investigation, ISSN 0021-9738, 03/2009, Volume 119, Issue 3, pp. 524 - 530
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Mice, Knockout - genetics | Up-Regulation | Vascular Diseases - prevention & control | Body Weight | Down-Regulation | Oxidative Stress - genetics | Vascular Diseases - genetics | Blood Glucose | Heart Diseases - prevention & control | Mitochondrial Proteins - genetics | Longevity - genetics | Energy Intake | Nicotinamide Phosphoribosyltransferase - genetics | Phenotype | Rotarod Performance Test | Animals | Sirtuin 3 | Adaptor Proteins, Signal Transducing - genetics | Mice | Sirtuins - genetics | Cytokines - genetics | Heart Diseases - genetics | Hypertension | Complications and side effects | Causes of | Genetic aspects | Research | Longevity | Renin-angiotensin system | Health aspects | Index Medicus | Abridged Index Medicus
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