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Journal Article
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 02/2014, Volume 306, Issue 4, pp. H585 - H597
Microvascular insufficiency contributes to cardiac hypertrophy and worsens heart dysfunction in diabetic cardiomyopathy. Our recent study shows that apelin may... 
VEGF/VEGFR2 | Diabetic cardiomyopathy | Angiogenesis | Sirtuin 3 | Ang-1/Tie-2 | Apelin | NADPH OXIDASE | METABOLIC SYNDROME | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | apelin | sirtuin 3 | angiogenesis | HEART-FAILURE | diabetic cardiomyopathy | TUMOR ANGIOGENESIS | PEPTIDE APELIN | IMPAIRED ANGIOGENESIS | CARDIAC-HYPERTROPHY | PERIPHERAL VASCULAR DISEASE | ORPHAN RECEPTOR APJ | EXPRESSION | ENDOTHELIAL GROWTH-FACTOR | Diabetic Cardiomyopathies - metabolism | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Male | Vascular Endothelial Growth Factor A - metabolism | Angiopoietin-1 - metabolism | Vascular Endothelial Growth Factor A - genetics | Angiopoietin-2 - metabolism | Diabetic Cardiomyopathies - physiopathology | Receptors, Vascular Endothelial Growth Factor - metabolism | Myocardium - metabolism | Neovascularization, Pathologic - physiopathology | Receptor, TIE-2 - metabolism | Diabetic Cardiomyopathies - therapy | Receptors, Vascular Endothelial Growth Factor - genetics | Neovascularization, Pathologic - therapy | Heart - physiopathology | Sirtuin 3 - genetics | Endothelium, Vascular - physiopathology | Intercellular Signaling Peptides and Proteins - genetics | Up-Regulation - genetics | Adipokines | Receptor, TIE-2 - genetics | Diabetic Cardiomyopathies - genetics | Angiopoietin-1 - genetics | Animals | Endothelium, Vascular - metabolism | Neovascularization, Pathologic - genetics | Mice | Neovascularization, Pathologic - metabolism | Apoptosis - physiology | Prevention | Cardiomyopathy | Physiological aspects | Genetic research | Genetic aspects | Research | Diabetes | Gene therapy | Heart diseases | VEGFR2 | Tie-2 | VEGF | Ang-1 | Integrative Cardiovascular Physiology and Pathophysiology
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2015, Volume 125, Issue 2, pp. 715 - 726
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 8, p. e23295
Background: Sirtuins (SIRT1-7) are a family of NAD-dependent deacetylases and/or ADP-ribosyltransferases that are involved in metabolism, stress responses and... 
RESPIRATORY-CHAIN | COMPLEX-II | METABOLISM | FATTY-ACID OXIDATION | SIRT3-MEDIATED DEACETYLATION | MITOCHONDRIA | BIOLOGY | LYSINE ACETYLATION | STRESS | CALORIE RESTRICTION | PROTEOMICS | Immunoprecipitation | Sirtuin 3 - metabolism | Humans | Substrate Specificity | Immunoblotting | Male | Mitochondrial Proteins - genetics | Succinate Dehydrogenase - chemistry | Mice, 129 Strain | Protein Subunits - metabolism | Mitochondrial Proteins - metabolism | HEK293 Cells | Female | Acetylation | Fibroblasts - metabolism | Protein Subunits - genetics | Protein Structure, Tertiary | Sirtuin 3 - genetics | Mice, Inbred C57BL | Cells, Cultured | Models, Molecular | Binding Sites - genetics | Mice, Knockout | Succinate Dehydrogenase - genetics | Animals | Embryo, Mammalian - cytology | Mitochondrial Proteins - chemistry | Protein Binding | Succinate Dehydrogenase - metabolism | Adipose Tissue, Brown - metabolism | Mice | Protein Subunits - chemistry | Physiological aspects | Enzymes | Electron transport | Mass spectrometry | Sirtuins | Succinate dehydrogenase | Phosphorylation | Dehydrogenases | Adipose tissue | Enzyme activity | Biochemistry | Biology | Dehydrogenase | ADP | Medical schools | Proteins | Electron transport chain | Mitochondria | Enzymatic activity | Aging | Oxidation | Adipose tissue (brown) | Mass spectroscopy | Metabolism | Mammals | SIRT1 protein | Substrates | NAD | Proteomics | Ligands | Scientific imaging
Journal Article
Cancer Research, ISSN 0008-5472, 10/2012, Volume 72, Issue 19, pp. 5130 - 5140
Journal Article
Journal Article
Nature Communications, ISSN 2041-1723, 04/2015, Volume 6, Issue 1, p. 6656
Honokiol (HKL) is a natural biphenolic compound derived from the bark of magnolia trees with anti-inflammatory, anti-oxidative, anti-tumour and neuroprotective... 
METABOLISM | GENE | SIRT3-MEDIATED DEACETYLATION | PATHWAY | PROTEIN-KINASE | MULTIDISCIPLINARY SCIENCES | HOMOLOG | AKT | SIRTUINS | CALORIE RESTRICTION | CELL-DEATH | Mitochondria - enzymology | Fibroblasts - enzymology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Sirtuin 3 - metabolism | Myofibroblasts - enzymology | Superoxide Dismutase - antagonists & inhibitors | Cardiomegaly - pathology | Isoproterenol | Lignans - pharmacology | Myocytes, Cardiac - enzymology | Phenylephrine - pharmacology | Biphenyl Compounds - pharmacology | Membrane Proteins - metabolism | Superoxide Dismutase - metabolism | Myofibroblasts - pathology | Sirtuin 3 - genetics | Signal Transduction | Membrane Proteins - genetics | Carrier Proteins - antagonists & inhibitors | Gene Expression Regulation | Adenosine Triphosphatases - metabolism | Myocardium - pathology | Cardiotonic Agents - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Fibroblasts - pathology | Myofibroblasts - drug effects | Adenosine Triphosphatases - antagonists & inhibitors | Carrier Proteins - genetics | Myocytes, Cardiac - pathology | Acetylation - drug effects | Myocardium - enzymology | Reactive Oxygen Species - antagonists & inhibitors | Animals | Cardiomegaly - prevention & control | Carrier Proteins - metabolism | Myocytes, Cardiac - drug effects | Membrane Proteins - antagonists & inhibitors | Cell Differentiation - drug effects | Fibroblasts - drug effects | Cardiomegaly - chemically induced | Adenosine Triphosphatases - genetics | Cell Proliferation - drug effects | Mice | Enzyme Activation | Primary Cell Culture | Cardiomegaly - genetics
Journal Article