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Science, ISSN 0036-8075, 5/2009, Volume 324, Issue 5927, pp. 651 - 654
The circadian clock is encoded by a transcription-translation feedback loop that synchronizes behavior and metabolism with the light-dark cycle. Here we report... 
RNA | Hepatocytes | Liver | Genes | Oscillation | Control loops | Reports | Biosynthesis | Gene expression regulation | Metabolism | Research universities | LIFE-SPAN | CELLS | GLUCOSE-HOMEOSTASIS | MULTIDISCIPLINARY SCIENCES | TRANSCRIPTION | NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE | EXTENSION | COMPONENT | SIRT1 | BINDING | CALORIE RESTRICTION | Humans | Adipose Tissue, White - metabolism | Hepatocytes - metabolism | Nicotinamide Phosphoribosyltransferase - antagonists & inhibitors | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nicotinamide Phosphoribosyltransferase - metabolism | Piperidines - pharmacology | Sirtuin 1 | NAD - biosynthesis | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Transcription, Genetic | Biological Clocks | Nuclear Proteins - genetics | Acrylamides - pharmacology | Cytokines - genetics | ARNTL Transcription Factors | Cell Line | Basic Helix-Loop-Helix Transcription Factors - genetics | Cytokines - metabolism | Liver - metabolism | Enzyme Inhibitors - pharmacology | Gene Expression Regulation | Transcription Factors - genetics | Circadian Rhythm | Period Circadian Proteins | Feedback, Physiological | Nicotinamide Phosphoribosyltransferase - genetics | Animals | CLOCK Proteins | Cell Line, Tumor | Protein Binding | Trans-Activators - metabolism | Mice | Cytokines - antagonists & inhibitors | Sirtuins - metabolism | Enzymes | Circadian rhythm | Cellular biology | Animal behavior | Rodents
Journal Article
Cell Reports, ISSN 2211-1247, 09/2016, Volume 17, Issue 1, pp. 69 - 85
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2010, Volume 107, Issue 17, pp. 7927 - 7932
Journal Article
Science, ISSN 0036-8075, 8/2004, Volume 305, Issue 5686, pp. 1010 - 1013
Journal Article
Journal Article
F1000Research, ISSN 2046-1402, 2018, Volume 7, p. 132
Nicotinamide adenine dinucleotide (NAD +) biosynthesis and its regulation have recently been attracting markedly increasing interest. Aging is marked by a... 
Small Molecule Chemistry | NAD | Biosynthesis Aging | NADPH | Sirtuins | Enzymes | Disease | Neurodegenerative diseases | Mental disorders | Homeostasis | Adenine | Biosynthesis | Metabolism | Kinases | DNA repair | Intermediates | Proteins | Aging | Physiology | Nicotinamide | Stress response | Deoxyribonucleic acid--DNA | Metabolic disorders
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2013, Volume 51, Issue 4, pp. 506 - 518
Journal Article
Journal Article
FEBS Letters, ISSN 0014-5793, 06/2011, Volume 585, Issue 11, pp. 1657 - 1662
► This review discusses a systemic regulatory network regulating metabolism and aging. ► SIRT1 functions as a key mediator controlling metabolic responses in... 
Aging | Longevity | NAD World | SIRT1 | NAD biosynthesis | NAMPT | COMPLEX | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELLS | RESTRICTION | SIRTUINS | CIRCADIAN CONTROL | CELL BIOLOGY | STIMULATED INSULIN-SECRETION | BIOPHYSICS | PATHWAY | GLUCOSE | MICE | ADIPOSE-TISSUE | Sirtuin 1 - metabolism | Animals | Nicotinamide Phosphoribosyltransferase - metabolism | Humans | NAD - biosynthesis | Aging - metabolism | longevity | aging
Journal Article