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eLife, ISSN 2050-084X, 2014, Volume 3
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 12/2005, Volume 48, Issue 25, pp. 8045 - 8054
Journal Article
Molecular and Cellular Proteomics, ISSN 1535-9476, 12/2011, Volume 10, Issue 12, pp. M111.012658 - M111.012658
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 06/2005, Volume 280, Issue 22, pp. 21313 - 21320
Journal Article
Journal Article
Biochemistry, ISSN 0006-2960, 12/2001, Volume 40, Issue 51, pp. 15456 - 15463
The Sir2 enzyme family is responsible for a newly classified chemical reaction, NAD(+)-dependent protein deacetylation. New peptide substrates, the reaction... 
NAD | SIR2-LIKE PROTEINS | YEAST SIR2 GENE | ACETYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DNA-DAMAGE | ADP-RIBOSYLATION | PROTEIN SIR2 | SACCHAROMYCES-CEREVISIAE | HOMOLOGY | P53 | Fungal Proteins - chemistry | Sirtuins | Adenosine Diphosphate Ribose - chemical synthesis | Adenosine Diphosphate Ribose - analogs & derivatives | Humans | Adenosine Diphosphate Ribose - metabolism | Archaeal Proteins - chemistry | Bacterial Proteins - chemistry | Molecular Sequence Data | Substrate Specificity | Trans-Activators - chemistry | Isomerism | NAD - chemistry | O-Acetyl-ADP-Ribose | Sirtuin 2 | Sirtuin 1 | Enzyme Inhibitors - chemistry | Adenosine Diphosphate Ribose - chemistry | Trans-Activators - genetics | Nuclear Magnetic Resonance, Biomolecular | Archaeal Proteins - genetics | NAD - metabolism | Amino Acid Sequence | Arabinose - chemistry | Histone Deacetylases - genetics | Bacterial Proteins - genetics | Gene Silencing | Histone Deacetylases - chemistry | Histone Deacetylases - metabolism | Fungal Proteins - genetics | Deuterium Oxide - metabolism | Oxygen Isotopes - metabolism | Trans-Activators - metabolism | Histone Deacetylase Inhibitors | Kinetics | Trans-Activators - antagonists & inhibitors | Silent Information Regulator Proteins, Saccharomyces cerevisiae | Enzymes | Gene silencing | Analysis | Structure-activity relationship | Cellular signal transduction | Research | Enzyme kinetics | Genetic regulation | Index Medicus
Journal Article
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2016, Volume 291, Issue 13, pp. 7128 - 7141
Journal Article
Proteins: Structure, Function, and Bioinformatics, ISSN 0887-3585, 07/2015, Volume 83, Issue 7, pp. 1316 - 1326
Protein families involved in chromatin‐templated events are emerging as novel target classes in oncology and other disease areas. The ability to discover... 
selectivity | binding pocket | chromatin factors | inhibitor | drug design | pocketome | epigenetics | structure | Binding pocket | Epigenetics | Drug design | Inhibitor | Selectivity | Pocketome | Structure | Chromatin factors | PROTEIN METHYLTRANSFERASES | L3MBTL1 | READERS | METHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DRUG DISCOVERY | DOT1L | BROMODOMAINS | BIOPHYSICS | BIOLOGY | LYMPHOMA | Small Molecule Libraries - pharmacology | Histones - chemistry | Antineoplastic Agents - chemical synthesis | Epigenesis, Genetic | Humans | Protein-Arginine N-Methyltransferases - antagonists & inhibitors | Neoplasm Proteins - antagonists & inhibitors | Acetyltransferases - genetics | DNA, Neoplasm - chemistry | Neoplasms - chemistry | Neoplasms - genetics | Sirtuins - chemistry | Databases, Protein | RNA, Neoplasm - antagonists & inhibitors | Acetyltransferases - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Protein-Arginine N-Methyltransferases - genetics | Neoplasm Proteins - genetics | Sirtuins - genetics | Binding Sites | Chromatin - drug effects | Histones - antagonists & inhibitors | Protein-Arginine N-Methyltransferases - chemistry | Chromatin - chemistry | Protein Structure, Tertiary | RNA, Neoplasm - chemistry | Models, Molecular | Small Molecule Libraries - chemical synthesis | Neoplasm Proteins - chemistry | Antineoplastic Agents - chemistry | Acetyltransferases - chemistry | Neoplasms - drug therapy | Small Molecule Libraries - chemistry | Histones - genetics | Protein Binding | RNA, Neoplasm - genetics | DNA, Neoplasm - antagonists & inhibitors | Ligands | Protein Processing, Post-Translational | Software | DNA, Neoplasm - genetics | Internet | Neoplasms - pathology | Sirtuins - antagonists & inhibitors | Histones | Epigenetic inheritance | RNA | Analysis | Genomics | Protein binding | Index Medicus
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2005, Volume 280, Issue 17, pp. 17038 - 17045
Journal Article
Cell Metabolism, ISSN 1550-4131, 12/2013, Volume 18, Issue 6, pp. 920 - 933
Journal Article