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PLoS ONE, ISSN 1932-6203, 03/2016, Volume 11, Issue 3, p. e0150392
Recent studies suggest that Sirt inhibition may have beneficial effects on several human diseases such as neurodegenerative diseases and cancer. Coffee is one... 
MECHANISM | ACETYLATION | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | RISK | TAU | CONSUMPTION | BETA | Sirtuin 1 - metabolism | Magnetic Resonance Spectroscopy | Humans | Tumor Suppressor Protein p53 - metabolism | Caffeic Acids - chemical synthesis | Tryptophan - chemical synthesis | Tryptophan - chemistry | Caffeic Acids - pharmacology | Tryptophan - isolation & purification | Caffeic Acids - chemistry | Chromatography, High Pressure Liquid | Sirtuin 1 - antagonists & inhibitors | Sirtuin 2 - metabolism | Caffeic Acids - isolation & purification | Coffee - chemistry | Acetylation - drug effects | Tubulin - metabolism | Tryptophan - analogs & derivatives | Drug Design | Cell Line, Tumor | Sirtuin 2 - antagonists & inhibitors | Molecular Docking Simulation | Tryptophan - pharmacology | Histones - metabolism | Apoptotic proteins | Research | Coffee | Analysis | High performance liquid chromatography | Enzymes | Nuclear magnetic resonance--NMR | Disease | Neurodegenerative diseases | p53 Protein | Substrate inhibition | Biosynthesis | Liquid chromatography | Metabolism | Kinases | High-performance liquid chromatography | SIRT1 protein | Diseases | Neurological diseases | Proteins | NAD | Inhibitors | Lysine | Docking | Acetylation | Beverages | Histone H3 | Cancer | Nuclear magnetic resonance | NMR
Journal Article
Molecules, ISSN 1420-3049, 2018, Volume 23, Issue 2, p. 333
NAD(+)-dependent histone deacetylases (sirtuins) are implicated in cellular processes such as proliferation, DNA repair, and apoptosis by regulating gene... 
Sirtuin inhibitor | Epigenetics | Eurochevalierine | Natural compound | Cytostatic compound | Cancer | HDAC | cytostatic compound | SECONDARY METABOLITES | NATURAL-PRODUCTS | NEOSARTORYA-PSEUDOFISCHERI | BIOCHEMISTRY & MOLECULAR BIOLOGY | natural compound | DEATH | sirtuin inhibitor | HUMAN CANCER-CELLS | CHEMISTRY, MULTIDISCIPLINARY | epigenetics | eurochevalierine | PROPIDIUM IODIDE | EPIGENETIC MODULATORS | TARGETS | cancer | AGENTS | LEUKEMIA | Sirtuin 1 - metabolism | Sesquiterpenes - isolation & purification | Sirtuin 3 - metabolism | Humans | Alkaloids - isolation & purification | Gene Expression Regulation, Neoplastic | Tubulin - genetics | Sirtuin 1 - genetics | Sirtuin 2 - metabolism | Tubulin - metabolism | Antineoplastic Agents - isolation & purification | Sirtuin 2 - antagonists & inhibitors | Antineoplastic Agents - pharmacology | Protein Interaction Domains and Motifs | Acetylation | Binding Sites | Neosartorya - metabolism | Protein Conformation, alpha-Helical | Sirtuin 3 - genetics | Alkaloids - pharmacology | Sesquiterpenes - chemistry | Neosartorya - chemistry | Antineoplastic Agents - chemistry | Histone Deacetylase Inhibitors - chemistry | Histone Deacetylase Inhibitors - isolation & purification | Sirtuin 1 - antagonists & inhibitors | Sirtuin 2 - genetics | Histones - genetics | Protein Conformation, beta-Strand | Protein Binding | Histone Deacetylase Inhibitors - pharmacology | Molecular Docking Simulation | Protein Processing, Post-Translational | Histones - metabolism | Sesquiterpenes - pharmacology | Alkaloids - chemistry | Sirtuins | Cell proliferation | Cell culture | Drug development | DNA repair | Modulators | Optimization | Anticancer properties | Proteins | Fungi | Tubulin | Docking | Inhibition | Deoxyribonucleic acid--DNA | CD34 antigen | Therapeutic applications | Gene expression | Progenitor cells | NAD | Histone H4 | Computer applications | Stem cells | Cells (biology) | Viability | Apoptosis
Journal Article
Molecular Cell, ISSN 1097-2765, 01/2013, Volume 49, Issue 1, pp. 186 - 199
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Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 12/2018, Volume 120, Issue Pt A, pp. 683 - 692
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 2007, Volume 367, Issue 5, pp. 1246 - 1257
Journal Article
Cell Cycle, ISSN 1538-4101, 02/2013, Volume 12, Issue 4, pp. 555 - 578