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Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 7519 - 12
In silico network-based methods have shown promising results in the field of drug development. Yet, most of networks used in the previous research have not... 
SYSTEM | DATABASE | RENIN | GENE | PATHWAY | MULTIDISCIPLINARY SCIENCES | TISSUE | KEGG | NEBIVOLOL | HYPERTENSION | BLOOD-PRESSURE | Hematologic Diseases - pathology | Liver - pathology | Metabolic Diseases - pathology | Respiratory Tract Diseases - metabolism | Kidney - pathology | Skin - metabolism | Hematologic Diseases - metabolism | Humans | Muscle, Skeletal - metabolism | Respiratory Tract Diseases - drug therapy | Respiratory Tract Diseases - genetics | Brain - metabolism | Musculoskeletal Diseases - pathology | Kidney - metabolism | Liver - drug effects | Muscle, Skeletal - drug effects | Myocardium - metabolism | Nervous System Diseases - metabolism | Nutrition Disorders - pathology | Computational Biology - methods | Kidney - drug effects | Liver - metabolism | Nervous System Diseases - drug therapy | Connective Tissue Diseases - metabolism | Neoplasms - drug therapy | Brain - drug effects | Connective Tissue Diseases - drug therapy | Connective Tissue Diseases - pathology | Lung - drug effects | Brain - pathology | Hematologic Diseases - genetics | Prescription Drugs - pharmacokinetics | Digestive System Diseases - pathology | Neoplasms - metabolism | Cardiovascular Diseases - drug therapy | Drugs, Investigational - pharmacokinetics | Respiratory Tract Diseases - pathology | Hematologic Diseases - drug therapy | Metabolic Diseases - drug therapy | Cardiovascular Diseases - pathology | Nervous System Diseases - genetics | Cardiovascular Diseases - genetics | Musculoskeletal Diseases - genetics | Neoplasms - genetics | Lung - metabolism | Skin - pathology | Nervous System Diseases - pathology | Lung - pathology | Musculoskeletal Diseases - drug therapy | Cardiovascular Diseases - metabolism | Musculoskeletal Diseases - metabolism | Nutrition Disorders - drug therapy | Nutrition Disorders - genetics | Myocardium - pathology | Organ Specificity | Digestive System Diseases - genetics | Algorithms | Digestive System Diseases - drug therapy | Nutrition Disorders - metabolism | Metabolic Diseases - metabolism | Digestive System Diseases - metabolism | Metabolic Diseases - genetics | Connective Tissue Diseases - genetics | Muscle, Skeletal - pathology | Neoplasms - pathology | Skin - drug effects | Drug development | Index Medicus
Journal Article
Pharmacology and the skin, ISSN 1011-291X, 1987
Journal
European Journal of Pharmaceutics and Biopharmaceutics, ISSN 0939-6411, 10/2017, Volume 119, pp. 142 - 149
Journal Article
Journal Article
Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2013, Volume 8, Issue 1, pp. e53745 - e53745
Background: Ipilimumab, a cytotoxic T-lymphocyte antigen-4 (CTLA-4) blocking antibody, has been approved for the treatment of metastatic melanoma and induces... 
TRIAL | CTLA-4 BLOCKADE | INDUCED SARCOIDOSIS | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | AUTOIMMUNE-DISEASES | PHASE-I/II | MULTIDISCIPLINARY SCIENCES | TREMELIMUMAB CP-675,206 | MONOCLONAL-ANTIBODY | PATIENT | CANCER | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Neoplasm Metastasis | Liver - drug effects | Antineoplastic Agents - adverse effects | Aged, 80 and over | Endocrine System - drug effects | Adult | Female | Retrospective Studies | Antibodies, Monoclonal - immunology | Kidney - drug effects | Antineoplastic Agents - immunology | Pancreas - drug effects | Gastrointestinal Tract - drug effects | Melanoma - pathology | CTLA-4 Antigen - immunology | Nervous System - drug effects | Melanoma - drug therapy | Respiratory System - drug effects | Aged | Skin - drug effects | Antimitotic agents | Antigens | Care and treatment | Algorithms | Lymphocytes | Melanoma | Skin | Metastasis | Antineoplastic agents | Skin cancer | Cancer | Aseptic meningitis | Guillain-Barre syndrome | Exanthema | Central nervous system | Blocking antibodies | Cytotoxicity | Oncology | Lymphocytes T | Metastases | CTLA-4 protein | Intestine | Gastroenterology | Meningitis | Internal medicine | Hematology | Sarcoidosis | Dermatology | Management | Regression analysis | Patients | Eosinophilia | Morbidity | Inflammatory bowel disease | Pathology | Side effects | Hospitals | Perforations | Medical prognosis | Antitumor activity | Autoimmune diseases | Endocrinology | Index Medicus
Journal Article
04/2015, 2015, ISBN 3662450127, 340
This truly comprehensive reference, in a mini-series format with five volumes, offers a detailed description of both well-known and recently introduced methods... 
Drug delivery systems | Dermatopharmacology | Transdermal medication | Medicine & Public Health | Pharmacology/Toxicology | Dermatology | Skin absorption
eBook
Development (Cambridge), ISSN 0950-1991, 05/2016, Volume 143, Issue 10, pp. 1674 - 1687
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 6, pp. e1004174 - e1004174
Bacterial signaling systems are prime drug targets for combating the global health threat of antibiotic resistant bacterial infections including those caused... 
NADPH OXIDASE | ANTIBIOTICS | LYTTR DOMAIN | GLOBAL GENE-EXPRESSION | MICROBIOLOGY | VIRULENCE | IDENTIFICATION | DISCOVERY | VIROLOGY | DISEASE | INFECTION | SKIN | PARASITOLOGY | Staphylococcus epidermidis - physiology | Skin - microbiology | Molecular Conformation | Bacterial Proteins - chemistry | Male | Promoter Regions, Genetic - drug effects | Trans-Activators - chemistry | Staphylococcal Skin Infections - immunology | Anti-Bacterial Agents - adverse effects | Macrophages - microbiology | Triazoles - therapeutic use | Bacterial Proteins - antagonists & inhibitors | Quorum Sensing - drug effects | Mice, Knockout | Macrophages - metabolism | Staphylococcus epidermidis - growth & development | Staphylococcus aureus - immunology | Anti-Bacterial Agents - pharmacology | Molecular Docking Simulation | Quinazolinones - chemistry | Mutation | Staphylococcal Skin Infections - microbiology | Triazoles - adverse effects | Staphylococcus epidermidis - drug effects | Staphylococcus aureus - physiology | Staphylococcus epidermidis - immunology | Triazoles - chemistry | Anti-Bacterial Agents - therapeutic use | Staphylococcal Skin Infections - drug therapy | Anti-Bacterial Agents - chemistry | Trans-Activators - genetics | Macrophages - immunology | Quinazolinones - pharmacology | Molecular Targeted Therapy - adverse effects | Phagocytosis - drug effects | Immunity, Innate - drug effects | Bacterial Proteins - genetics | Mice, Hairless | Drug Discovery | Triazoles - pharmacology | Animals | High-Throughput Screening Assays | Bacterial Proteins - metabolism | Genes, Reporter - drug effects | Macrophages - drug effects | Trans-Activators - metabolism | Quinazolinones - therapeutic use | Trans-Activators - antagonists & inhibitors | Staphylococcus aureus - drug effects | Staphylococcus aureus - growth & development | Cell Line, Transformed | Quinazolinones - adverse effects | Skin - drug effects | Staphylococcus aureus infections | Physiological aspects | Development and progression | Genetic aspects | Quorum sensing | Virulence (Microbiology) | Research | Staphylococcus aureus | Index Medicus | Medical research | Bacteria | Staphylococcus infections | Bacterial infections | Antibiotics | Bacteriology
Journal Article