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The Journal of immunology (1950), ISSN 1550-6606, 2014, Volume 193, Issue 3, pp. 1246 - 1257
Malarial infection is initiated when the sporozoite form of the Plasmodium parasite is inoculated into the skin by a mosquito. Sporozoites invade hepatocytes... 
LIVER-STAGE | IMMUNIZATION | RODENT MALARIA PARASITES | PROTECTIVE IMMUNITY | CD8+ T-CELLS | CIRCUMSPOROZOITE PROTEIN | HOST-CELL TRAVERSAL | MOSQUITO | DRAINING LYMPH-NODE | IMMUNOLOGY | STERILE PROTECTION | Inflammation - pathology | Plasmodium berghei - immunology | Skin - cytology | Humans | CD8-Positive T-Lymphocytes - parasitology | Inflammation - parasitology | Sporozoites - immunology | Female | Injections, Intradermal | Skin - immunology | Plasmodium berghei - parasitology | Cell Line | Sporozoites - transplantation | Anopheles - parasitology | Malaria - immunology | Mice, Inbred C57BL | Skin - parasitology | Sporozoites - radiation effects | Mice, Transgenic | Host-Parasite Interactions - immunology | Inflammation - immunology | Lymph Nodes - immunology | Antigen Presentation - immunology | Hep G2 Cells | Animals | Lymph Nodes - parasitology | Ear | Malaria - parasitology | Mice | Anopheles - immunology | CD8-Positive T-Lymphocytes - immunology | Malaria/immunology | Antigen Presentation/immunology | Lymph Nodes/immunology | Sporozoites/transplantation | Inflammation/immunology | Life Sciences | Lymph Nodes/parasitology | CD8-Positive T-Lymphocytes/immunology | Immunology | Skin/cytology | Sporozoites/radiation effects | Anopheles/immunology | Inflammation/pathology | Plasmodium berghei/parasitology | Plasmodium berghei/immunology | Inflammation/parasitology | Skin/parasitology | CD8-Positive T-Lymphocytes/parasitology | Sporozoites/immunology | Host-Parasite Interactions/immunology | Skin/immunology | Anopheles/parasitology | Malaria/parasitology
Journal Article
Nature reviews. Immunology, ISSN 1474-1741, 2009, Volume 9, Issue 7, pp. 491 - 502
Journal Article
Arthritis & rheumatology (Hoboken, N.J.), ISSN 2326-5191, 2016, Volume 68, Issue 10, pp. 2492 - 2502
Objective Antinuclear antibodies (ANAs) are detected in ∼18% of females, yet autoimmune disease develops in only 5–8%. Immunologic differences between... 
SYSTEMIC-LUPUS-ERYTHEMATOSUS | INTERFERON | CYTOKINE PRODUCTION | RISK-FACTORS | DENDRITIC CELLS | ANTINUCLEAR ANTIBODIES | RHEUMATOLOGY | EXPRESSION | SLE | IG-LIKE RECEPTOR-1 | T-CELLS | Interferon-alpha - pharmacology | Multivariate Analysis | Phosphoproteins - drug effects | Interferon-beta - immunology | Antibodies, Antinuclear - immunology | Humans | Middle Aged | Interleukin-17 - immunology | STAT1 Transcription Factor - drug effects | Centromere Protein B - immunology | Male | Monocytes - immunology | Ribosomal Proteins - immunology | Healthy Volunteers | Case-Control Studies | Leukocytes - immunology | Young Adult | Flow Cytometry | Autoimmunity - immunology | Lupus Erythematosus, Systemic - immunology | Ribonucleoproteins - immunology | Tumor Necrosis Factor-alpha - immunology | Aged, 80 and over | Adult | B-Lymphocyte Subsets - immunology | Female | Interleukin-12 Subunit p40 - immunology | Cytokines - immunology | Interleukin 1 Receptor Antagonist Protein - immunology | Immunophenotyping | Logistic Models | Nuclear Proteins - immunology | STAT1 Transcription Factor - immunology | Stem Cell Factor - immunology | Interferon-alpha - immunology | Autoantibodies - immunology | Interferon-gamma - immunology | STAT3 Transcription Factor - drug effects | Sex Factors | Aged | Granulocyte Colony-Stimulating Factor - immunology | STAT3 Transcription Factor - immunology | Plasma Cells - immunology | Systemic Lupus Erythematosus
Journal Article
Journal of clinical oncology, ISSN 1527-7755, 2012, Volume 30, Issue 21, pp. 2691 - 2697
Monoclonal antibodies directed against the immune checkpoint protein cytotoxic T-lymphocyte antigen-4 (CTLA-4; CD152)-ipilimumab and tremelimumab-have been... 
REGRESSION | METASTATIC MELANOMA | LYMPHOCYTE-ASSOCIATED ANTIGEN-4 | EFFICACY | ONCOLOGY | PHASE-II | MONOCLONAL-ANTIBODY | CTLA-4 | PATIENT | CANCER-IMMUNOTHERAPY | BLOCKADE | Stevens-Johnson Syndrome - immunology | Peripheral Nervous System Diseases - chemically induced | Skin Neoplasms - drug therapy | Humans | Ipilimumab | Antibodies, Monoclonal - adverse effects | Scleritis - chemically induced | Antineoplastic Agents - administration & dosage | Liver - immunology | Liver - drug effects | Antineoplastic Agents - adverse effects | Diarrhea - immunology | Pancreatitis - immunology | Scleritis - immunology | Mucous Membrane - drug effects | Colitis - immunology | Peripheral Nervous System Diseases - immunology | Antibodies, Monoclonal - immunology | Drug Eruptions - immunology | Skin - immunology | Melanoma - metabolism | Skin Neoplasms - pathology | Skin Neoplasms - immunology | Antineoplastic Agents - immunology | CTLA-4 Antigen - drug effects | Lymphatic Diseases - immunology | Antibodies, Monoclonal - pharmacokinetics | CTLA-4 Antigen - immunology | Pancreatitis - chemically induced | Melanoma - secondary | Chemical and Drug Induced Liver Injury - immunology | Pituitary Gland - immunology | Skin Neoplasms - metabolism | Lymphatic Diseases - chemically induced | Mucous Membrane - immunology | Antibodies, Monoclonal - administration & dosage | Melanoma - immunology | Uveitis - immunology | Melanoma - drug therapy | Uveitis - chemically induced | Pituitary Gland - drug effects | Skin - drug effects | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0175153
IL-1 beta is a potent player in cutaneous inflammation and central for the development of a Th17 micro-milieu in autoinflammatory diseases including psoriasis.... 
VITAMIN-D | SYSTEMIC-LUPUS-ERYTHEMATOSUS | INTERFERON-GAMMA | MULTIDISCIPLINARY SCIENCES | PSORIASIN S100A7 | INFLAMMATORY CASPASES | KERATINOCYTES | 1,25-DIHYDROXYVITAMIN D-3 | MOLECULAR-CLONING | EXPRESSION | T-CELLS | Caspases - immunology | Humans | Interleukin-17 - immunology | Interleukin-17 - pharmacology | Interleukin-1beta - genetics | S100 Proteins - immunology | Psoriasis - genetics | S100 Proteins - genetics | Th17 Cells - drug effects | Transfection | Inflammasomes - drug effects | Psoriasis - pathology | Adaptor Proteins, Signal Transducing - immunology | Apoptosis Regulatory Proteins - genetics | Skin - pathology | Skin - immunology | Th17 Cells - pathology | Interleukin-1beta - secretion | Psoriasis - immunology | S100 Calcium Binding Protein A7 | Apoptosis Regulatory Proteins - immunology | DNA - immunology | Signal Transduction | Caspases - genetics | Cells, Cultured | Gene Expression Regulation | Interleukin-17 - genetics | Interleukin-1beta - immunology | Vitamin D - pharmacology | Keratinocytes - cytology | Keratinocytes - immunology | DNA - genetics | Interleukin-17 - antagonists & inhibitors | Keratinocytes - drug effects | Inflammasomes - immunology | Adaptor Proteins, Signal Transducing - genetics | Th17 Cells - immunology | Interferon-gamma - pharmacology | Interleukins | Physiological aspects | Development and progression | Skin diseases | Genetic aspects | Inflammation | Research | Cell culture | Transcription | Interleukin | Helper cells | Lymphocytes T | Inflammatory diseases | Vitamin D | Lymphocytes | Interleukin 1 | Lesions | Deoxyribonucleic acid--DNA | Psoriasis | Cytokines | Dermatology | Keratinocytes | Caspase | Epidermis | Hazards | Gene expression | Caspase-5 | Hospitals | Biopsy | Interferon | Autoimmune diseases | Apoptosis | Deoxyribonucleic acid | DNA
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2013, Volume 110, Issue 32, pp. 13097 - 13102
Skin homeostasis is critical to preserve animal integrity. Although the skin of most vertebrates is known to contain a skin-associated lymphoid tissue (SALT),... 
Immunoglobulins | Microbiota | B lymphocytes | Antibodies | Bacteria | Skin | Mucus | Infections | Parasites | Mammals | Evolution | Ichthyophthirius multifiliis | Cutaneous | Mucosal immunoglobulin | cutaneous | COLLECTION | IGA | RAINBOW-TROUT | DENDRITIC CELLS | MULTIDISCIPLINARY SCIENCES | mucosal immunoglobulin | evolution | IDENTIFICATION | DERMATOLOGY | B-CELLS | IMMUNOGLOBULIN-A | LYMPHOID-TISSUE | FISH | Immunity, Mucosal - immunology | Skin - microbiology | Immunoglobulins - immunology | Mucous Membrane - parasitology | Immunoglobulin M - immunology | Fish Diseases - parasitology | Host-Pathogen Interactions - immunology | Lymphoid Tissue - immunology | Hymenostomatida - immunology | Epidermis - parasitology | Gastrointestinal Tract - immunology | Bacteria - immunology | Flow Cytometry | Oncorhynchus mykiss - microbiology | Epidermis - microbiology | Immunoglobulins - blood | Fish Diseases - immunology | B-Lymphocyte Subsets - immunology | Oncorhynchus mykiss - immunology | Oncorhynchus mykiss - parasitology | Skin - immunology | Fish Diseases - microbiology | Skin - parasitology | Host-Parasite Interactions - immunology | Blotting, Western | Animals | B-Lymphocytes - immunology | Immunoglobulin M - blood | Epidermis - immunology | Mucous Membrane - immunology | Hymenostomatida - physiology | Microscopy, Fluorescence | Mucous Membrane - microbiology | Physiological aspects | Homeostasis | Immune response | Research | Teleostei | Biological Sciences
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 135, Issue 6, pp. 1625 - 1635.e5
Background Remodeling of quiescent vessels with increases in permeability, vasodilatation, and edema are hallmarks of inflammatory disorders. Factors involved... 
Allergy and Immunology | Peroxisome proliferator-activated receptor β/δ | smooth muscle cells | endothelium | anaphylaxis | vascular permeability | SIGNALING PATHWAYS | NITRIC-OXIDE SYNTHASE | DELTA | MAST-CELLS | DIABETIC-RATS | IMMUNOLOGY | ALLERGY | INFLAMMATION | IN-VIVO | VE-CADHERIN | Peroxisome proliferator-activated receptor beta/delta | ADHERENS JUNCTIONS | PPAR-BETA/DELTA | Edema - genetics | Myocytes, Smooth Muscle - pathology | Capillary Permeability - drug effects | Capillary Permeability - immunology | Hypothermia - immunology | Intercellular Junctions - immunology | Hypothermia - pathology | Proto-Oncogene Proteins c-akt - genetics | Thrombin - pharmacology | Intercellular Junctions - pathology | Anaphylaxis - immunology | PPAR delta - immunology | Female | Mitogen-Activated Protein Kinases - immunology | Myocytes, Smooth Muscle - drug effects | Vascular Endothelial Growth Factor A - pharmacology | PPAR delta - genetics | Skin - pathology | Skin - immunology | PPAR delta - deficiency | Edema - immunology | Histamine - pharmacology | Signal Transduction | Anaphylaxis - pathology | Gene Expression Regulation | Mice, Transgenic | PPAR-beta - immunology | PPAR-beta - genetics | PPAR-beta - deficiency | Anaphylaxis - genetics | Endothelial Cells - immunology | Skin - blood supply | Animals | Proto-Oncogene Proteins c-akt - immunology | Intercellular Junctions - drug effects | Myocytes, Smooth Muscle - immunology | Mitogen-Activated Protein Kinases - genetics | Mice | Endothelial Cells - pathology | Edema - pathology | Hypothermia - genetics | Skin - drug effects | Endothelial Cells - drug effects | Mitogen-Activated Protein Kinases/genetics | Skin/blood supply | Endothelial Cells/drug effects | Endothelial Cells/immunology | Intercellular Junctions/immunology | PPAR delta/immunology | Skin/pathology | Intercellular Junctions/drug effects | Hypothermia/genetics | Capillary Permeability/drug effects | Life Sciences | PPAR delta/genetics | PPAR delta/deficiency | Hypothermia/immunology | Immunology | Anaphylaxis/genetics | Histamine/pharmacology | PPAR-beta/immunology | Myocytes, Smooth Muscle/pathology | Anaphylaxis/pathology | Myocytes, Smooth Muscle/immunology | Endothelial Cells/pathology | Hypothermia/pathology | Vascular Endothelial Growth Factor A/pharmacology | Mitogen-Activated Protein Kinases/immunology | Myocytes, Smooth Muscle/drug effects | Edema/immunology | Proto-Oncogene Proteins c-akt/genetics | Edema/pathology | Skin/immunology | Intercellular Junctions/pathology | Proto-Oncogene Proteins c-akt/immunology | Edema/genetics | PPAR-beta/genetics | Skin/drug effects | PPAR-beta/deficiency | Thrombin/pharmacology
Journal Article