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1. Full Text Skin ageing
by Kohl, E and Steinbauer, J and Landthaler, M and Szeimies, R.‐M
Journal of the European Academy of Dermatology and Venereology, ISSN 0926-9959, 08/2011, Volume 25, Issue 8, pp. 873 - 884
Similar to the entire organism, skin is subject to an unpreventable intrinsic ageing process. Additionally, skin ageing is also influenced by exogenous... 
UV radiation | photoageing | extrinsic skin ageing | matrix metalloproteinases | intrinsic skin ageing | retinoids | PHOTOAGED SKIN | GREEN TEA POLYPHENOLS | AGED HUMAN SKIN | INFRARED RADIATION | HORMONE REPLACEMENT THERAPY | MITOCHONDRIAL-DNA | DERMATOLOGY | ULTRAVIOLET-B IRRADIATION | IN-VIVO | DOUBLE-BLIND | POSTMENOPAUSAL WOMEN | Skin Aging - pathology | Skin - cytology | Reactive Oxygen Species - metabolism | Skin - metabolism | DNA Repair Enzymes - pharmacology | Humans | Skin Aging - drug effects | Polyphenols - pharmacology | Skin Aging - radiation effects | Antioxidants - pharmacology | Ultraviolet Rays - adverse effects | Collagen - metabolism | Skin Aging - physiology | Sunscreening Agents - pharmacology | Matrix Metalloproteinases - metabolism | Retinoids - pharmacology | Care and treatment | Skin | Retinoids | Collagen | Radiation
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2. Full Text Anti-Aging Potentials of Methylene Blue for Human Skin Longevity
by Mei Xiong, Zheng and O'Donovan, Mike and Sun, Linlin and Young Choi, Ji and Ren, Margaret and Cao, Kan
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 2475 - 12
Oxidative stress is the major cause of skin aging that includes wrinkles, pigmentation, and weakened wound healing ability. Application of antioxidants in skin... 
PATHWAYS | OXIDATIVE STRESS | IN-VITRO | MULTIDISCIPLINARY SCIENCES | DISEASE | STRATUM-CORNEUM | MITOCHONDRIAL DYSFUNCTION | DIFFERENTIATION | PROGERIA | THICKNESS | AGE | Elastin - metabolism | Skin Aging - pathology | Longevity - drug effects | Humans | Skin Aging - drug effects | Cellular Senescence - drug effects | Skin - growth & development | Antioxidants - pharmacology | Longevity - genetics | Mitochondria - drug effects | Methylene Blue - pharmacology | Collagen - metabolism | Fibroblasts - drug effects | Cell Proliferation - drug effects | Oxidative Stress - drug effects | Wound Healing - drug effects | Skin - drug effects | Oxidative stress | Reactive oxygen species | Senescence | Wound healing | Elastin | Dermis | Gene expression | Pigmentation | Cosmetics industry | Methylene blue | Antioxidants | Mitochondria | Progeria | Collagen | Aging | Fibroblasts | Extracellular matrix | Skin | Skin tests | Irritation
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3. Full Text Skin aging and oxidative stress: Equol's anti-aging effects via biochemical and molecular mechanisms
by Lephart, Edwin D
Ageing Research Reviews, ISSN 1568-1637, 11/2016, Volume 31, pp. 36 - 54
Oxygen in biology is essential for life. It comes at a cost during normal cellular function, where reactive oxygen species (ROS) are generated by oxidative... 
Oxidative stress | Human skin | Free radicals | Anti-aging | Antioxidant | Equol | AGE-ASSOCIATED REDUCTION | S-EQUOL | NERVE GROWTH-FACTOR | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | ESTROGEN-RECEPTOR-BETA | IN-VITRO | GENE-EXPRESSION | POSTMENOPAUSAL WOMEN | NF-KAPPA-B | FED BREAST-MILK | TRANSCRIPTION FACTOR | Reactive Oxygen Species - metabolism | Signal Transduction | Skin - metabolism | Antioxidants - metabolism | Humans | Skin Aging - drug effects | Oxidative Stress - drug effects | Phytoestrogens - therapeutic use | Oxygen - metabolism | Equol - therapeutic use | Antioxidants | Physiological aspects | Care and treatment | Skin | Developmental biology | Steroid hormones | Neurosciences | Radiation | Plant extracts | Free radicals (Chemistry) | Materia medica, Vegetable | Food
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4. Full Text Anti-ageing and rejuvenating effects of quercetin
by Chondrogianni, Niki and Kapeta, Suzanne and Chinou, Ioanna and Vassilatou, Katerina and Papassideri, Issidora and Gonos, Efstathios S
Experimental Gerontology, ISSN 0531-5565, 2010, Volume 45, Issue 10, pp. 763 - 771
Homeostasis is a key feature of the cellular lifespan. Its maintenance influences the rate of ageing and it is determined by several factors, including... 
Anti-ageing | Quercetin caprylate | Quercetin | Rejuvenation | Proteasome | CANCER-CELLS | SURVIVAL | OXIDATIVE STRESS | DIETARY FLAVONOIDS | PROTEASOME INHIBITION | GERIATRICS & GERONTOLOGY | SENESCENCE-LIKE PHENOTYPE | LIFE-SPAN EXTENSION | CAENORHABDITIS-ELEGANS | SIGNALING PATHWAY | HUMAN FIBROBLASTS | Cell Line | Quercetin - chemistry | Antioxidants - chemistry | Humans | Aging - drug effects | Melanocytes - metabolism | Antioxidants - pharmacology | Cytoprotection - physiology | Skin Pigmentation - drug effects | Animals | Proteasome Endopeptidase Complex - drug effects | Quercetin - pharmacology | Melanocytes - cytology | Melanocytes - drug effects | Fibroblasts - drug effects | Cytoprotection - drug effects | Skin Pigmentation - physiology | Fibroblasts - cytology | Mice | Proteasome Endopeptidase Complex - metabolism | Aging - metabolism | Fibroblasts - metabolism | Phosphates | Trypsin | Proteolysis | Analysis | Albumin | Physiological aspects | Fatty acids
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5. Full Text Role of antioxidants in the skin: Anti-aging effects
by Masaki, Hitoshi
Journal of Dermatological Science, ISSN 0923-1811, 2010, Volume 58, Issue 2, pp. 85 - 90
Abstract Intracellular and extracellular oxidative stress initiated by reactive oxygen species (ROS) advance skin aging, which is characterized by wrinkles and... 
Dermatology | Antioxidant | Oxidative stress | ROS | HUMAN DERMAL FIBROBLASTS | NITRIC-OXIDE SYNTHESIS | ALPHA-TOCOPHEROL | HUMAN MELANOCYTES | ULTRAVIOLET-LIGHT | L-ASCORBIC-ACID | DERMATOLOGY | IN-VITRO | HYDROGEN-PEROXIDE | NRF2-KEAP1 SIGNALING PATHWAY | Reactive Oxygen Species | Oxidative Stress | Skin - metabolism | Antioxidants - metabolism | Humans | Aging - drug effects | Inflammation | Phenols - metabolism | Skin Aging | Ascorbic Acid - metabolism | Ultraviolet Rays | Models, Biological | Flavonoids - metabolism | Carotenoids - metabolism | Polyphenols | Vitamin E - metabolism | Sebaceous Glands - metabolism
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6. Full Text Anti‐aging pharmacology in cutaneous wound healing: effects of metformin, resveratrol, and rapamycin by local application
by Zhao, Pan and Sui, Bing‐Dong and Liu, Nu and Lv, Ya‐Jie and Zheng, Chen‐Xi and Lu, Yong‐Bo and Huang, Wen‐Tao and Zhou, Cui‐Hong and Chen, Ji and Pang, Dan‐Lin and Fei, Dong‐Dong and Xuan, Kun and Hu, Cheng‐Hu and Jin, Yan
Aging Cell, ISSN 1474-9718, 10/2017, Volume 16, Issue 5, pp. 1083 - 1093
Cutaneous wounds are among the most common soft tissue injuries and are particularly hard to heal in aging. Caloric restriction ( CR ) is well documented to... 
anti‐aging pharmacology | aged skin | wound healing | AMPK | pathway | metformin | vascularization | anti-aging pharmacology | AMPK pathway | ACTIVATED PROTEIN-KINASE | ANGIOGENESIS | PROLIFERATION | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | SKELETAL-MUSCLE | REPAIR | SIGNALING PATHWAY | MICE | GROWTH-FACTOR | CONTRIBUTES | Cyclin D1 - metabolism | Neovascularization, Physiologic - drug effects | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - genetics | AMP-Activated Protein Kinases - metabolism | Ribosomal Protein S6 Kinases - metabolism | Wounds, Nonpenetrating - drug therapy | Administration, Cutaneous | Stilbenes - pharmacology | Skin - injuries | Acetyl-CoA Carboxylase - genetics | Tumor Suppressor Protein p53 - genetics | Aging - genetics | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha - metabolism | Female | Wound Healing - drug effects | Metformin - pharmacology | Skin Aging - drug effects | Gene Expression Regulation | Tumor Suppressor Protein p53 - metabolism | Cyclin-Dependent Kinase Inhibitor p16 - genetics | Rats | Wounds, Nonpenetrating - enzymology | Skin - enzymology | Rats, Sprague-Dawley | Sirolimus - pharmacology | Skin - blood supply | Neovascularization, Physiologic - physiology | Animals | Cyclin D1 - genetics | Cyclin-Dependent Kinase Inhibitor p16 - metabolism | Mice | Wound Healing - physiology | Wounds, Nonpenetrating - pathology | Enzyme Activation | Ribosomal Protein S6 Kinases - genetics | Wounds, Nonpenetrating - genetics | AMP-Activated Protein Kinases - genetics | Acetyl-CoA Carboxylase - metabolism | Skin - drug effects | Aging - metabolism | Care and treatment | Wound healing | Collagen | Resveratrol | Pharmacology | Skin | Hypoglycemic agents | Adenylic acid | Wounds and injuries | Hair | AMP | Epidermis | Rapamycin | Longevity | Follicles | Kinases | Vascularization | Dietary restrictions | Angiogenesis | Protein kinase | Adenosine kinase | Rodents | Aging | Metformin | Original
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7. Full Text Sunscreen and prevention of skin aging: A randomized trial
by Hughes, Maria Celia B and Williams, Gail M and Baker, Peter and Green, Adèle C
Annals of Internal Medicine, ISSN 0003-4819, 06/2013, Volume 158, Issue 11, pp. 781 - 790
Background: Sunscreen use and dietary antioxidants are advocated as preventives of skin aging, but supporting evidence is lacking. Objective: To determine... 
SUPPLEMENTATION | MEDICINE, GENERAL & INTERNAL | SUN EXPOSURE | PROTECTION | INVIVO | MECHANISMS | SMOKING | CANCER | PARTICIPANTS | BASAL-CELL | PHOTODAMAGE | Antioxidants - therapeutic use | beta Carotene - therapeutic use | Humans | Middle Aged | Skin Aging - drug effects | Adult | Female | Male | Dietary Supplements | Sunscreening Agents - therapeutic use | Prevention | Usage | Sunscreens (Cosmetics) | Aging | Skin | Research | Health aspects | Beta carotene | Vitamin A | Sunscreen | Dermatology | Clinical outcomes | Dietary supplements | Skin care products
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8. Full Text Bioactive compounds from natural resources against skin aging
by Mukherjee, Pulok K and Maity, Niladri and Nema, Neelesh K and Sarkar, Birendra K
Phytomedicine, ISSN 0944-7113, 2011, Volume 19, Issue 1, pp. 64 - 73
Skin aging involves degradation of extracellular matrix (ECM) in both the epidermal and dermal layers, it leaves visible signs on the surface of skin and the... 
Cosmetics | Phytomolecules | Ayurveda | Skin aging | Photo-aging | Wrinkles | CHEMISTRY, MEDICINAL | HAMAMELIS-VIRGINIANA | CENTELLA-ASIATICA | HUMAN DERMAL FIBROBLASTS | GREEN TEA EXTRACTS | INHIBITORY-ACTIVITY | HUMAN KERATINOCYTES | PLANT SCIENCES | INDUCED WRINKLE FORMATION | RETRACTED ARTICLE. SEE | MATRIX METALLOPROTEINASE-1 | INTEGRATIVE & COMPLEMENTARY MEDICINE | I PROCOLLAGEN | PHARMACOLOGY & PHARMACY | Cosmetics - pharmacology | Animals | Plant Extracts - pharmacology | Humans | Skin Aging - drug effects | Biological Products - pharmacology | Skin Aging - physiology | Phytotherapy | Prevention | Care and treatment | Medicine, Botanic | Aging | Medicine, Herbal | Skin | Genetic aspects | Research | Health aspects
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9. Full Text Anti-skin-aging effect of epigallocatechin gallate by regulating epidermal growth factor receptor pathway on aging mouse model induced by d-Galactose
by Chen, Jiming and Li, Yifan and Li, Tong and Zhu, Qiangqiang and Lu, Hao and Wei, Nan and Huang, Yewei and Shi, Ruoyu and Ma, Xiao and Wang, Xuanjun and Sheng, Jun
Mechanisms of Ageing and Development, ISSN 0047-6374, 06/2017, Volume 164, pp. 1 - 7
Epigallocatechin gallate(EGCG) is a monomer separated from tea catechins, as an well-known antioxidant, which helps fight wrinkles and rejuvenate skin cells.... 
EGFR pathway | d-galactose | Oxidative stress | Anti-skin-aging | EGCG | D-galactose | GREEN TEA | CELLS | MECHANISMS | MICE | PULMONARY-FIBROSIS | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | Receptor, Epidermal Growth Factor - metabolism | Animals | Signal Transduction - drug effects | Models, Biological | Skin Aging - drug effects | Galactose - toxicity | Male | Catechin - analogs & derivatives | Mice | Catechin - pharmacology | Catechin | Care and treatment | Skin | Epidermal growth factor | Galactose | Analysis | Antioxidants | Skin care products
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10. Full Text Ultraviolet radiation, aging and the skin: Prevention of damage by topical cAMP manipulation
by Amaro-Ortiz, Alexandra and Yan, Betty and D'Orazio, John A
Molecules, ISSN 1420-3049, 2014, Volume 19, Issue 5, pp. 6202 - 6219
Being the largest and most visible organ of the body and heavily influenced by environmental factors, skin is ideal to study the long-term effects of aging.... 
UV radiation | Aging | Oxidative stress | Skin | Forskolin | INDUCED DNA-DAMAGE | forskolin | BIOCHEMISTRY & MOLECULAR BIOLOGY | skin | CELLULAR SENESCENCE | HUMAN MELANOCYTES | CHEMISTRY, MULTIDISCIPLINARY | SUN EXPOSURE | SIGNALING PATHWAY | CUTANEOUS MELANOMA | MELANOCORTIN-1 RECEPTOR | DERMAL FIBROBLASTS | HYDROGEN-PEROXIDE | aging | oxidative stress | Melanoma - metabolism | Skin Neoplasms - pathology | Plant Extracts - chemistry | Skin Neoplasms - drug therapy | Humans | Middle Aged | Aging - drug effects | Aging - radiation effects | Melanoma - pathology | Aging - pathology | Skin Neoplasms - metabolism | Plant Extracts - administration & dosage | Plectranthus - chemistry | Ultraviolet Rays | Skin - radiation effects | Melanoma - drug therapy | Administration, Topical | Cyclic AMP - metabolism | DNA Damage - radiation effects | Skin - pathology
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11. Full Text Anti-aging effects of ingenol mebutate for patients with actinic keratosis
by Kim, Miri and Kim, Jongsic and Jung, Yujin and Jeong, Seo-won and Woo, Yu Ri and Park, Hyun Jeong
Journal of the American Academy of Dermatology, ISSN 0190-9622, 12/2018, Volume 79, Issue 6, pp. 1148 - 1150
GEL | DERMATOLOGY | Diterpenes - therapeutic use | Gels | Skin - metabolism | Humans | Middle Aged | Skin Aging - drug effects | Rejuvenation | Male | Matrix Metalloproteinase 1 - biosynthesis | Treatment Outcome | Administration, Cutaneous | Transforming Growth Factor beta - biosynthesis |