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Human Pathology, ISSN 0046-8177, 2013, Volume 44, Issue 11, pp. 2563 - 2570
Summary BRAF mutation is seen in a variety of human neoplasms including cutaneous malignant melanoma, papillary thyroid carcinoma, colorectal carcinoma,... 
Pathology | Immunohistochemistry | Anti–B-Raf | BRAF V600E | VE1 | Glioma | Melanoma | Thyroid carcinoma | Anti-B-Raf | PROTEIN | IMPROVED SURVIVAL | PATHOLOGY | CANCER | TUMORS | HAIRY-CELL LEUKEMIA | THERAPY | MEK INHIBITION | GENE | MUTANT BRAF | VEMURAFENIB | Neoplasms - metabolism | Gastrointestinal Neoplasms - genetics | Humans | Lung Neoplasms - metabolism | Ovarian Neoplasms - pathology | Lung Neoplasms - pathology | Mutation, Missense | Breast Neoplasms - metabolism | Glioma - metabolism | Glioma - genetics | Ovarian Neoplasms - genetics | Gastrointestinal Neoplasms - pathology | Neoplasms - genetics | DNA Mutational Analysis | Melanoma - genetics | Glioma - pathology | Sensitivity and Specificity | Biomarkers, Tumor - metabolism | Female | Ovarian Neoplasms - metabolism | Carcinoma - pathology | Antibodies, Monoclonal - immunology | Proto-Oncogene Proteins B-raf - metabolism | Gastrointestinal Neoplasms - metabolism | Lung Neoplasms - genetics | Melanoma - metabolism | Mutant Proteins - genetics | Mutant Proteins - metabolism | Melanoma - pathology | Thyroid Neoplasms - genetics | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Proto-Oncogene Proteins B-raf - genetics | Carcinoma - genetics | Biomarkers, Tumor - genetics | Carcinoma - metabolism | Neoplasms - pathology | Amino Acid Substitution | Thyroid Neoplasms - metabolism | Thyroid Neoplasms - pathology | Carcinoma | Gene mutations | Gliomas | Thyroid diseases | Monoclonal antibodies | Genetic aspects | Comparative analysis | Lung cancer, Non-small cell | Cancer | Breast cancer | Mutation | Tumors | Skin cancer | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2009, Volume 137, Issue 6, pp. 1976 - 1985.e10
Background & Aims MUTYH -associated polyposis (MAP) is characterized by a lifetime risk of colorectal cancer of up to 100%. However, no systematic evaluation... 
Gastroenterology and Hepatology | BASE-EXCISION-REPAIR | URINARY-TRACT CANCER | APC GENE MUTATION | MUIR-TORRE-SYNDROME | NONPOLYPOSIS COLORECTAL-CANCER | DUODENAL ADENOMATOSIS | FAMILIAL ADENOMATOUS POLYPOSIS | MYH-ASSOCIATED POLYPOSIS | LYNCH SYNDROME | GASTROENTEROLOGY & HEPATOLOGY | MSH2 MUTATION CARRIERS | Gastrointestinal Neoplasms - genetics | Humans | Middle Aged | Adenomatous Polyposis Coli - epidemiology | Ovarian Neoplasms - pathology | Male | Adenomatous Polyposis Coli - pathology | Incidence | Ovarian Neoplasms - genetics | Young Adult | Gastrointestinal Neoplasms - pathology | Gastrointestinal Neoplasms - epidemiology | Urinary Bladder Neoplasms - genetics | Urinary Bladder Neoplasms - pathology | Adult | Female | Retrospective Studies | Endoscopy | Adenomatous Polyposis Coli - genetics | Child | Urinary Bladder Neoplasms - epidemiology | Breast Neoplasms - epidemiology | Skin Neoplasms - pathology | Genetic Predisposition to Disease | Sebaceous Gland Neoplasms - epidemiology | Risk Assessment | Risk Factors | Sebaceous Gland Neoplasms - genetics | DNA Glycosylases - genetics | Kaplan-Meier Estimate | Europe - epidemiology | Skin Neoplasms - epidemiology | Ovarian Neoplasms - epidemiology | Phenotype | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Sebaceous Gland Neoplasms - pathology | Skin Neoplasms - genetics | Adolescent | Age of Onset | Aged | Medical colleges | Animal pigments | Genetic disorders | Oncology, Experimental | Colorectal cancer | Research | Cancer | Tumors | Medical informatics | Index Medicus | Abridged Index Medicus
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2013, Volume 230, Issue 3, pp. 261 - 269
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 17, Issue 6, pp. 738 - 746
Journal Article
Journal Article
Journal of Clinical Oncology, ISSN 0732-183X, 12/2015, Volume 33, Issue 34, pp. 4032 - 4038
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 7/2011, Volume 128, Issue 2, pp. 447 - 456
Trastuzumab (T) is effective in metastatic breast cancer (MBC) with HER2 overexpression and/or amplification, but resistance to T develops in a significant... 
Medicine & Public Health | PIK3CA | Predictive | PTEN | Oncology | Breast cancer | HER2 | Trastuzumab | 1ST-LINE TREATMENT | MARKER | SAFETY | DOCETAXEL | CHEMOTHERAPY | PHASE-II TRIAL | ONCOLOGY | RECOMMENDATIONS | RESISTANCE | CORRELATE | COOPERATIVE-ONCOLOGY-GROUP | Lung Neoplasms - drug therapy | Receptors, Estrogen - metabolism | Follow-Up Studies | Receptor, ErbB-2 - genetics | Tissue Array Analysis | Humans | Middle Aged | Receptor, ErbB-2 - metabolism | Bone Neoplasms - secondary | Antibodies, Monoclonal - therapeutic use | Antineoplastic Agents - therapeutic use | Immunoenzyme Techniques | Receptors, Progesterone - metabolism | Antibodies, Monoclonal, Humanized | Lung Neoplasms - secondary | Time Factors | Polymerase Chain Reaction | Aged, 80 and over | Adult | Female | Bone Neoplasms - genetics | Retrospective Studies | Bone Neoplasms - drug therapy | Liver Neoplasms - secondary | Proto-Oncogene Proteins c-akt - metabolism | Lung Neoplasms - genetics | PTEN Phosphohydrolase - genetics | Liver Neoplasms - genetics | Liver Neoplasms - drug therapy | In Situ Hybridization, Fluorescence | Survival Rate | Treatment Outcome | Lymphatic Metastasis | Mutation - genetics | Breast Neoplasms - drug therapy | Disease Progression | Phosphatidylinositol 3-Kinases - genetics | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Breast Neoplasms - pathology | Polymorphism, Single Nucleotide - genetics | Aged | DNA, Neoplasm - genetics | Immunohistochemistry | Care and treatment | Medical records | Metastasis | Antineoplastic agents | Formaldehyde | Antimitotic agents | Analysis | Cytogenetics | Genetic aspects | Health aspects | Cancer | Index Medicus
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 09/2013, Volume 133, Issue 9, pp. 2229 - 2236
Congenital melanocytic nevi (CMN) can be associated with neurological abnormalities and an increased risk of melanoma. Mutations in , , and have been described... 
MC1R | VARIANTS | RAS | BRAF MUTATIONS | HIGH-FREQUENCY | PHENOTYPE | NEUROLOGICALLY ASYMPTOMATIC CHILDREN | ASSOCIATION | REGISTRY | MOSAICISM | DERMATOLOGY | Meningeal Neoplasms - epidemiology | Prevalence | Nevus, Pigmented - epidemiology | Humans | Child, Preschool | Male | Neurocutaneous Syndromes - congenital | Meningioma - genetics | Mutation, Missense - genetics | Loss of Heterozygosity - genetics | Hamartoma - pathology | Young Adult | Hamartoma - genetics | Nevus, Pigmented - genetics | Meningioma - epidemiology | Zygote | Female | Genetic Predisposition to Disease - epidemiology | Neurocutaneous Syndromes - epidemiology | Child | Melanosis - epidemiology | Melanosis - genetics | Neurocutaneous Syndromes - genetics | Genetic Predisposition to Disease - genetics | Meningeal Neoplasms - genetics | Membrane Proteins - genetics | Central Nervous System Neoplasms - genetics | Risk Factors | Hamartoma - epidemiology | Central Nervous System Neoplasms - epidemiology | Melanosis - congenital | Skin Neoplasms - epidemiology | Nevus, Pigmented - congenital | Magnetic Resonance Imaging | Meningioma - pathology | Central Nervous System Neoplasms - pathology | GTP Phosphohydrolases - genetics | Skin Neoplasms - congenital | Skin Neoplasms - genetics | Adolescent | Mosaicism | Meningeal Neoplasms - pathology | Index Medicus | Original
Journal Article
Science, ISSN 0036-8075, 03/2016, Volume 351, Issue 6280, pp. 1463 - 1469
Journal Article