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Cell Stem Cell, ISSN 1934-5909, 09/2012, Volume 11, Issue 3, pp. 401 - 414
The integrity of the epidermis and mucosal epithelia is highly dependent on resident self-renewing stem cells, which makes them vulnerable to physical and... 
MAMMALIAN TARGET | CANCER PATIENTS | RAPAMYCIN | HEAD | AGING PHENOTYPES | MANGANESE SUPEROXIDE-DISMUTASE | STRESS-RESPONSE | TUMOR | NECK | SKIN | CELL & TISSUE ENGINEERING | CELL BIOLOGY | Cell Death - radiation effects | TOR Serine-Threonine Kinases - metabolism | Keratinocytes - radiation effects | Carcinoma, Squamous Cell - pathology | Epithelial Cells - drug effects | Humans | Cellular Senescence - drug effects | Cell Compartmentation - radiation effects | Mucositis - prevention & control | Mouth Mucosa - drug effects | TOR Serine-Threonine Kinases - antagonists & inhibitors | Mouth Mucosa - radiation effects | Mucositis - pathology | Stem Cells - enzymology | Mucositis - enzymology | Cellular Senescence - radiation effects | Cytoprotection - drug effects | Clone Cells | Oxidative Stress - radiation effects | Cell Death - drug effects | Head and Neck Neoplasms - enzymology | Mouth Mucosa - pathology | Keratinocytes - enzymology | Superoxide Dismutase - metabolism | Radiation, Ionizing | Carcinoma, Squamous Cell - enzymology | Epithelial Cells - radiation effects | Cells, Cultured | Stem Cells - radiation effects | Epithelial Cells - pathology | Radiation Injuries - enzymology | Sirolimus - pharmacology | Head and Neck Neoplasms - pathology | Keratinocytes - pathology | Animals | Keratinocytes - drug effects | Radiation Injuries - prevention & control | Epithelial Cells - enzymology | Cell Compartmentation - drug effects | Stem Cells - drug effects | Stem Cells - pathology | Radiation Injuries - pathology | Cell Proliferation - drug effects | Mice | Oxidative Stress - drug effects | Cytoprotection - radiation effects | Cell Proliferation - radiation effects
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2016, Volume 11, Issue 8, pp. e0159998 - e0159998
Recent research found that Tiron was an effective antioxidant that could act as the intracellular reactive oxygen species (ROS) scavenger or alleviate the... 
IRRADIATION | OXIDATIVE STRESS | HUMAN SKIN | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MECHANISMS | SODIUM 4,5-DIHYDROXYBENZENE-1,3-DISULFONATE | INDUCTION | C-JUN | NF-KAPPA-B | PROTEIN-KINASES | Promoter Regions, Genetic - radiation effects | Binding Sites - radiation effects | Humans | Transcriptional Activation - drug effects | Skin Aging - radiation effects | 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt - pharmacology | Promoter Regions, Genetic - drug effects | Transcription Factor AP-1 - metabolism | Dermis - drug effects | Cytoprotection - drug effects | Signal Transduction - radiation effects | Dermis - cytology | Matrix Metalloproteinase 1 - genetics | Fibroblasts - metabolism | MAP Kinase Signaling System - radiation effects | Dermis - metabolism | Skin Aging - drug effects | Transcriptional Activation - radiation effects | Cells, Cultured | Dermis - radiation effects | Matrix Metalloproteinase 3 - metabolism | Antioxidants - pharmacology | Ultraviolet Rays - adverse effects | MAP Kinase Signaling System - drug effects | Fibroblasts - radiation effects | Signal Transduction - drug effects | Fibroblasts - drug effects | Transcription Factor AP-1 - radiation effects | Cytoprotection - genetics | Matrix Metalloproteinase 1 - metabolism | Cytoprotection - radiation effects | Matrix Metalloproteinase 3 - genetics | Genetic aspects | Skin | Genetic transcription | RNA | Analysis | Enzyme-linked immunosorbent assay | Oxidative stress | Reactive oxygen species | Transcription factors | Senescence | Oncology | Activation | Matrix metalloproteinase | Kinases | Proteins | Antioxidants | Signal transduction | Consent | Transcription activation | Fibroblasts | Aging | Biocompatibility | Metalloproteinase | Interstitial collagenase | Stromelysin 1 | Wound healing | U.V. radiation | Activator protein 1 | MAP kinase | Gene expression | Medicine | Signaling | Collagen | In vivo methods and tests | Binding sites | Apoptosis | Index Medicus
Journal Article
Journal Article
JAMA, ISSN 0098-7484, 12/2017, Volume 318, Issue 23, pp. 2306 - 2316
Journal Article
Journal of the American Academy of Dermatology, ISSN 0190-9622, 2008, Volume 58, Issue 4, pp. 545 - 570
Chemotherapeutic agents give rise to numerous well described adverse effects that may affect the skin, hair, mucous membranes, or nails. The mucocutaneous... 
Dermatology | CELL LUNG-CANCER | CHRONIC MYELOGENOUS LEUKEMIA | GROWTH-FACTOR RECEPTOR | PEGYLATED LIPOSOMAL DOXORUBICIN | PHASE-II TRIAL | RADIATION-RECALL DERMATITIS | CHRONIC LYMPHOCYTIC-LEUKEMIA | TYROSINE-KINASE INHIBITOR | CHRONIC MYELOID-LEUKEMIA | HAND-FOOT SYNDROME | DERMATOLOGY | Erlotinib Hydrochloride | Niacinamide - analogs & derivatives | Drug Eruptions - pathology | Humans | Antibodies, Monoclonal - adverse effects | Phenylurea Compounds | Protein Kinase Inhibitors - adverse effects | Benzenesulfonates - adverse effects | Antibodies, Monoclonal, Humanized | Pyridines - adverse effects | Fusion Proteins, bcr-abl | Antineoplastic Agents - adverse effects | Nail Diseases - chemically induced | Drug-Related Side Effects and Adverse Reactions | Hair Diseases - chemically induced | Pyrroles - adverse effects | Mucous Membrane - drug effects | Cetuximab | Taxoids - adverse effects | Platinum Compounds - adverse effects | Drug Eruptions - etiology | Skin Diseases - chemically induced | Imatinib Mesylate | Piperazines - adverse effects | Antimetabolites - adverse effects | Indoles - adverse effects | Signal Transduction - drug effects | Pyrimidines - adverse effects | Quinazolines - adverse effects | Receptor, Epidermal Growth Factor - antagonists & inhibitors | Benzamides | Proteasome Inhibitors | Skin - drug effects | Protein-Tyrosine Kinases - antagonists & inhibitors | Chemotherapy | Platelet-derived growth factor | Formulae, receipts, prescriptions | Dermatologic agents | Lung cancer, Non-small cell | Cancer | Index Medicus
Journal Article
Experimental Dermatology, ISSN 0906-6705, 06/2009, Volume 18, Issue 6, pp. 553 - 561
:  Solar ultraviolet (UV) radiation, particularly its UVB (290–320 nm) component, is the primary cause of many adverse biological effects including photoageing... 
ultraviolet radiation | photoageing | human reconstituted skin | matrix metalloproteinases | DNA damage | pomegranate | Photoageing | Ultraviolet radiation | Matrix metalloproteinases | Human reconstituted skin | Pomegranate | CUTANEOUS CARCINOGENESIS | CELL NUCLEAR ANTIGEN | DNA-DAMAGE | INDUCED OXIDATIVE DAMAGE | KAPPA-B | RADIATION-INDUCED IMMUNOSUPPRESSION | DERMATOLOGY | PUNICA-GRANATUM POMEGRANATE | BOTANICAL ANTIOXIDANTS | DERMAL FIBROBLASTS | HUMAN EPIDERMAL-KERATINOCYTES | Matrix Metalloproteinases - genetics | Keratinocytes - radiation effects | Plant Extracts - pharmacology | Skin - metabolism | Coculture Techniques | Humans | Proto-Oncogene Proteins c-jun - biosynthesis | Proto-Oncogene Proteins c-fos - biosynthesis | Male | Protein Processing, Post-Translational - drug effects | Enzyme Induction - drug effects | Radiation-Protective Agents - pharmacology | Radiation-Protective Agents - isolation & purification | Oxidative Stress - radiation effects | Phosphorylation - drug effects | Drug Evaluation, Preclinical | Infant, Newborn | Matrix Metalloproteinases - biosynthesis | Organoids - radiation effects | DNA Damage - drug effects | Punicaceae - chemistry | Plant Oils - pharmacology | Protein Processing, Post-Translational - radiation effects | Plant Extracts - isolation & purification | Plant Oils - isolation & purification | Tropoelastin - biosynthesis | Ultraviolet Rays - adverse effects | Phosphorylation - radiation effects | Fibroblasts - radiation effects | Keratinocytes - drug effects | Tropoelastin - genetics | Skin - radiation effects | Fibroblasts - drug effects | Organoids - drug effects | Proto-Oncogene Proteins c-fos - genetics | Oxidative Stress - drug effects | DNA Damage - radiation effects | Enzyme Induction - radiation effects | Skin - drug effects | Antioxidants | Immunohistochemistry | Carbocyclic compounds | Anthocyanin | Tannins | Pyrimidines | DNA | Guanosine | Radiation | Chromophores | Skin cancer
Journal Article