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biochemistry & molecular biology (5) 5
biophysics (4) 4
animals (3) 3
calmodulin (3) 3
cell biology (3) 3
humans (3) 3
phosphorylation (3) 3
protein kinase inhibitors - pharmacology (3) 3
smmlck (3) 3
amino acid sequence (2) 2
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mlck (2) 2
muscle proteins (2) 2
myosin (2) 2
myosin light chain kinase (2) 2
protein kinase (2) 2
protein kinases (2) 2
1--2-methylpiperazine - analogs & derivatives (1) 1
1--2-methylpiperazine - pharmacology (1) 1
acc (1) 1
acetyl-coa carboxylase (1) 1
activated protein-kinase (1) 1
adenosine triphosphate - biosynthesis (1) 1
affinity (1) 1
aicar, aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (1) 1
amp-activated protein kinase (1) 1
ampk (1) 1
ampk, amp-activated protein kinase (1) 1
anilino naphthalenesulfonates - metabolism (1) 1
ans, 8-anilino-1-naphthalene-sulphonic acid (1) 1
anti-cancer drugs (1) 1
atf2, activating transcription factor 2 (1) 1
atm, ataxia telangiectasia mutated (1) 1
atp synthase (1) 1
atp synthesis (1) 1
autoinhibition (1) 1
binding-site (1) 1
brsk, brain-specific kinase (1) 1
ca2+/cam (1) 1
cabp, calcium binding protein (1) 1
cak, cyclin-dependent kinase-activating kinase (1) 1
calcium binding protein (1) 1
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calcium-binding proteins - metabolism (1) 1
calcium-calmodulin-dependent protein kinase type 2 - antagonists & inhibitors (1) 1
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calcium/calmodulin-dependent protein kinase 2 (1) 1
calmodulin - analogs & derivatives (1) 1
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cam (1) 1
cam, calmodulin (1) 1
camk, calmodulin-dependent kinase (1) 1
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camkk, camk kinase (1) 1
cdk, cyclin-dependent protein kinase (1) 1
cell structure (1) 1
cell-proliferation (1) 1
central helix (1) 1
chk, checkpoint kinase (1) 1
circular dichroism (1) 1
ck, casein kinase (1) 1
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contraction (1) 1
csk, c-terminal src kinase (1) 1
cyclic amp-dependent protein kinases - antagonists & inhibitors (1) 1
cyclin-dependent kinases (1) 1
d subunit (1) 1
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dogs (1) 1
drug design (1) 1
drug discovery (1) 1
dyrk, dual-specificity tyrosine-phosphorylated and -regulated kinase (1) 1
ef2k, elongation-factor-2 kinase (1) 1
egf, epidermal growth factor (1) 1
energy deprivation (1) 1
entamoeba histolytica - metabolism (1) 1
entamoeba-histolytica (1) 1
entropy (1) 1
enzyme activation (1) 1
eph-a2, ephrin a2 receptor (1) 1
erk, extracellular-signal-regulated kinase (1) 1
escherichia coli - metabolism (1) 1
expression (1) 1
family-members (1) 1
fgf-r, fibroblast-growth-factor receptor (1) 1
fkbp, fk506-binding protein (1) 1
fmk, fluoromethylketone (1) 1
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fof1 (1) 1
fret (1) 1
gak, cyclin g-associated kinase (1) 1
globular domains (1) 1
gsk3, glycogen synthase kinase 3 (1) 1
gst, glutathione transferase (1) 1
hek-293 cells, human embryonic kidney-293 cells (1) 1
hela cells (1) 1
hipk, homeodomain-interacting protein kinase (1) 1
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Biochemical journal, ISSN 1470-8728, 2007, Volume 408, Issue 3, pp. 297 - 315
The specificities of 65 compounds reported to be relatively specific inhibitors of protein kinases have been profiled against a panel of 70-80 protein kinases... 
Drug discovery | Kinase profiling | Protein kinase | Anti-cancer drugs | Inhibitor specificity | RHO-ASSOCIATED KINASE | TUMOR PROGRESSION | FAMILY-MEMBERS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-PROLIFERATION | protein kinase | P38 MAP KINASE | CYCLIN-DEPENDENT KINASES | RECEPTOR TYROSINE KINASES | drug discovery | kinase profiling | SB 203580 | anti-cancer drugs | ISOFORMS IN-VITRO | P90 RSK | inhibitor specificity | Amino Acid Sequence | Cell Line | Phosphorylation | Recombinant Proteins - antagonists & inhibitors | Animals | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Humans | Drug Design | Protein Kinase Inhibitors - pharmacology | Enzyme Activation | Mitogen-Activated Protein Kinases - metabolism | Spodoptera | Yes1, Yamaguchi sarcoma viral oncogene homologue 1 | CSK, C-terminal Src kinase | Lck, lymphocyte cell-specific protein-tyrosine kinase | EGF, epidermal growth factor | FGF-R, fibroblast-growth-factor receptor | PAK, p21-activated protein kinase | PDK, 3-phosphoinositide-dependent protein kinase | PI3K, phosphatidylinositol (phosphoinositide) 3-kinase | NEK, NIMA (never in mitosis in Aspergillus nidulans)-related kinase | RSK, p90 ribosomal S6 kinase | HEK-293 cells, human embryonic kidney-293 cells | VEGF, vascular endothelial growth factor (vasoendothelial growth factor) | EF2K, elongation-factor-2 kinase | CK, casein kinase | PTEN, phosphatase and tensin homologue deleted on chromosome 10 | ERK, extracellular-signal-regulated kinase | ATM, ataxia telangiectasia mutated | SRPK, serine-arginine protein kinase | IL-1, interleukin 1 | MNK, MAPK-integrating protein kinase | ROCK, Rho-dependent protein kinase | CaMKK, CaMK kinase | GST, glutathione transferase | MKK1, MAPK kinase-1 (also called MEK1, MAPK or ERK kinase 1) | GAK, cyclin G-associated kinase | FMK, fluoromethylketone | MST, mammalian homologue Ste20-like kinase | PKA, cAMP-dependent protein kinase | FKBP, FK506-binding protein | PPAR, peroxisome-proliferator-activated receptor | IKK, inhibitory κB kinase | PH, pleckstrin homology | MBP, myelin basic protein | AICAR, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside | MAPKAP-K, MAPK-activated protein kinase | Sf21, Spodoptera frugiperda (fall armyworm) 21 | MARK, microtubule-affinity-regulating kinase | PIM, provirus integration site for Moloney murine leukaemia virus | LPS, lipopolysaccharide | MSK, mitogen- and stress-activated protein kinase | MAPK, mitogen-activated protein kinase | MELK, maternal embryonic leucine-zipper kinase | His6, hexahistidine | CAK, cyclin-dependent kinase-activating kinase | Eph-A2, Ephrin A2 receptor | PLK, polo-like kinase | ATF2, activating transcription factor 2 | PKD, protein kinase D | Src, sarcoma kinase | AMPK, AMP-activated protein kinase | MMS, methyl methanesulfonate | CHK, checkpoint kinase | JNK, c-Jun N-terminal kinase | TORC1, mTOR (mammalian target of rapamycin)–raptor (regulatory associated protein of mTOR) complex | BRSK, brain-specific kinase | RIP2, receptor-interacting protein 2 | IGF-1, insulin-like growth factor-1 | S6K1, S6 kinase 1 | DYRK, dual-specificity tyrosine-phosphorylated and -regulated kinase | HIPK, homeodomain-interacting protein kinase | ZMP, aminoimidazole-4-carboxamide-1-β-D-ribofuranoside monophosphate | PRAK, p38-regulated activated kinase | PKC, protein kinase C | Src-I1, Src inhibitor 1 | TANK, TRAF (tumour-necrosis-factor-receptor-associated factor)-family-member-associated nuclear factor κB activator | NFAT, nuclear factor for activated T-cells | PHK, phosphorylase kinase | GSK3, glycogen synthase kinase 3 | PKB, protein kinase B (also called Akt) | CaMK, calmodulin-dependent kinase | CDK, cyclin-dependent protein kinase | NDRG, N-myc downstream-regulated gene | SmMLCK, smooth-muscle myosin light-chain kinase | TBK1, TANK-binding kinase 1 | PRK, protein kinase C-related kinase | SGK, serum- and glucocorticoid-induced kinase
Journal Article
FEBS letters, ISSN 0014-5793, 11/2013, Volume 587, Issue 23, pp. 3843 - 3847
... (myosin light chain kinase)-knockdown. Mitochondrial ATP synthase, a major ATP supplier in respiring cells, should be regulated in amount and in activity to respond to the varying demands of cells for ATP... 
ATP synthesis | ATP synthase | MLCK | FoF1 | Protein kinase | Myosin light chain kinase | smMLCK | mitochondrial activity of SLO-permeabilized cells assay | smooth muscle type myosin light chain kinase | PKA | voltage-dependent anion channel of mitochondria | PKC | calcium/calmodulin-dependent protein kinase 2 | CaMKII | VDAC | miRNA | protein kinase A | protein kinase C | microRNA used for knockdown | MASC assay | PHOSPHORYLATION | D SUBUNIT | BIOCHEMISTRY & MOLECULAR BIOLOGY | VIABILITY | MAMMALIAN-CELLS | CELL BIOLOGY | SYNTHASE | BIOPHYSICS | COMPLEX-I | FoF | EXPRESSION | MORPHOLOGY | Myosin-Light-Chain Kinase - genetics | Myosin-Light-Chain Kinase - metabolism | Humans | Myosin-Light-Chain Kinase - antagonists & inhibitors | Mitochondria - metabolism | Mitochondria - drug effects | Adenosine Triphosphate - biosynthesis | Calcium-Calmodulin-Dependent Protein Kinase Type 2 - antagonists & inhibitors | Mitochondrial Proton-Translocating ATPases - metabolism | Protein Subunits - metabolism | Mitochondrial Proton-Translocating ATPases - genetics | Protein Kinase Inhibitors - chemistry | Protein Kinase C-delta - antagonists & inhibitors | Protein Kinase Inhibitors - pharmacology | RNA, Small Interfering | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | HeLa Cells | Protein Subunits - genetics | Muscle proteins | Protein kinases | Myosin
Journal Article
FEBS letters, ISSN 0014-5793, 1999, Volume 461, Issue 1, pp. 19 - 24
Journal Article
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