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Journal Article
PLoS genetics, ISSN 1553-7404, 07/2017, Volume 13, Issue 7, pp. e1006887 - e1006887
MicroRNA cluster mirn23a has previously been shown to promote myeloid development at the expense of lymphoid development in overexpression and knockout mouse... 
Guanylate Kinases - genetics | NIH 3T3 Cells | Up-Regulation | Cell Proliferation | MicroRNAs - metabolism | Mitochondrial Proteins - genetics | Phosphatidylinositol 3-Kinases - metabolism | Mitochondrial Proteins - metabolism | Trans-Activators - genetics | Cell Cycle Proteins - genetics | Cell Differentiation | Membrane Proteins - metabolism | B-Lymphocytes - metabolism | Cell Line | Forkhead Box Protein O1 - metabolism | Promoter Regions, Genetic | Signal Transduction | Membrane Proteins - genetics | Down-Regulation | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Hematopoiesis - genetics | Phosphatidylinositol 3-Kinases - genetics | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Guanylate Kinases - metabolism | Trans-Activators - metabolism | Mice | MicroRNAs - genetics | Forkhead Box Protein O1 - genetics | Apoptosis | RNA sequencing | MicroRNA | Hematopoiesis | Physiological aspects | Genetic aspects | Genetic transcription | Observations | Methods | Cell culture | Flow cytometry | Polarization | Smad protein | Animal models | Transcription factors | Gene regulation | AKT protein | Kinases | Pax5 protein | Proteins | Signal transduction | Immunology | Pathways | FOXO1 protein | Bone marrow | Clusters | Bone morphogenetic proteins | miRNA | Buffers | Medical research | Transplants | Cell lineage | Runx1 protein | Pharmacology | Ribonucleic acid--RNA | 1-Phosphatidylinositol 3-kinase | Hemopoiesis | Cytometry | Inhibitors | Lymphocytes B | MicroRNAs | Stem cells | In vivo methods and tests | Differentiation | In vitro methods and tests | Cancer | Index Medicus | RNA | Ribonucleic acid
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 12/2009, Volume 69, Issue 23, pp. 8844 - 8852
.... TGF-beta induced accumulation of autophagosomes and conversion of microtubule-associated protein I light chain 3 and enhanced the degradation rate of long-lived proteins... 
Life Sciences & Biomedicine | Oncology | Science & Technology | Microtubule-Associated Proteins - genetics | Humans | Ubiquitin-Activating Enzymes - biosynthesis | Cell Growth Processes - physiology | JNK Mitogen-Activated Protein Kinases - metabolism | Autophagy - physiology | Proto-Oncogene Proteins - biosynthesis | Transforming Growth Factor beta - biosynthesis | Breast Neoplasms - metabolism | Transfection | Bcl-2-Like Protein 11 | Carcinoma, Hepatocellular - genetics | Apoptosis Regulatory Proteins - genetics | Liver Neoplasms - pathology | Apoptosis Regulatory Proteins - biosynthesis | Beclin-1 | Ubiquitin-Activating Enzymes - genetics | Liver Neoplasms - genetics | Membrane Proteins - genetics | Transforming Growth Factor beta - physiology | Proto-Oncogene Proteins - genetics | Microtubule-Associated Proteins - antagonists & inhibitors | Microtubule-Associated Proteins - biosynthesis | Autophagy-Related Protein 7 | Membrane Proteins - biosynthesis | Breast Neoplasms - genetics | Transforming Growth Factor beta - genetics | Autophagy-Related Protein 5 | Membrane Proteins - antagonists & inhibitors | Receptors, Transforming Growth Factor beta - metabolism | Breast Neoplasms - pathology | Ubiquitin-Activating Enzymes - antagonists & inhibitors | Adaptor Proteins, Signal Transducing - genetics | Apoptosis Regulatory Proteins - antagonists & inhibitors | Carcinoma, Hepatocellular - pathology | Liver Neoplasms - metabolism | Cell Line, Tumor | Adaptor Proteins, Signal Transducing - biosynthesis | Smad Proteins - metabolism | Carcinoma, Hepatocellular - metabolism | Index Medicus
Journal Article
Neuron (Cambridge, Mass.), ISSN 0896-6273, 02/2012, Volume 73, Issue 4, pp. 713 - 728
.... The basic helix-loop-helix transcription factors Olig1 and Olig2 promote myelination, whereas bone morphogenetic protein (BMP) and Wnt/β... 
Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Central Nervous System - ultrastructure | Microcephaly - genetics | Oligonucleotide Array Sequence Analysis | Embryo, Mammalian | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - deficiency | Caspase 3 - metabolism | Ki-67 Antigen - metabolism | Gene Expression Profiling | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Zinc Finger E-box Binding Homeobox 2 | Central Nervous System - physiology | Bone Morphogenetic Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Facies | Repressor Proteins - metabolism | Smad7 Protein - metabolism | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Hirschsprung Disease - pathology | Intellectual Disability - pathology | Models, Molecular | Smad Proteins - genetics | Oligodendrocyte Transcription Factor 2 | Signal Transduction - genetics | Mice, Knockout | Central Nervous System - cytology | Mice | Optic Nerve - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Oligodendroglia - metabolism | Immunoprecipitation | Age Factors | Hirschsprung Disease - genetics | Gene Expression Regulation, Developmental - genetics | Intellectual Disability - genetics | Myelin Sheath - metabolism | Cell Differentiation - genetics | Transfection | Microcephaly - pathology | Optic Nerve - embryology | Smad7 Protein - genetics | Optic Nerve - growth & development | Microscopy, Electron, Transmission | Cells, Cultured | Nerve Tissue Proteins - genetics | Organogenesis | Nerve Tissue Proteins - metabolism | Animals | Signal Transduction - physiology | Smad Proteins - metabolism | Medical colleges | Neurons | Central nervous system | Bone morphogenetic proteins | Universities and colleges | DNA binding proteins | Proteins | Multiple sclerosis | Transcription factors | Rodents | Nervous system | Genomes | Kinases | Gene expression | Index Medicus | Antagonism
Journal Article
PloS one, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e46307 - e46307
Bone morphogenetic proteins (BMPs) are members of the transforming growth factor beta superfamily that exert their effects via type I and type II serine threonine kinase receptors and the SMAD intracellular signaling pathway... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Bone Morphogenetic Protein 5 - chemistry | Bone Morphogenetic Protein 6 - chemistry | Bone Morphogenetic Protein 7 - chemistry | Hemochromatosis Protein | Bone Morphogenetic Protein 7 - genetics | Humans | Nerve Tissue Proteins - chemistry | Transfection | Bone Morphogenetic Protein 6 - genetics | Solutions | Growth Differentiation Factors - genetics | Genes, Reporter | Cell Line | Cell Adhesion Molecules, Neuronal - chemistry | Signal Transduction | Membrane Proteins - genetics | Bone Morphogenetic Protein 5 - genetics | Recombinant Proteins - chemistry | Histocompatibility Antigens Class I - genetics | Recombinant Proteins - genetics | Histocompatibility Antigens Class I - chemistry | Nerve Tissue Proteins - genetics | Cell Adhesion Molecules, Neuronal - genetics | GPI-Linked Proteins - chemistry | Membrane Proteins - chemistry | Protein Binding | Ligands | Kinetics | GPI-Linked Proteins - genetics | Growth Differentiation Factors - chemistry | Physiological aspects | Bone morphogenetic proteins | Genetic aspects | Research | Protein binding | Smad protein | Phosphorylation | Nephrology | Transforming growth factor-b | Homeostasis | Intracellular signalling | Iron | Biology | Kinases | Medical schools | Proteins | Signal transduction | Receptors | Rodents | Growth factors | Binding | Bone morphogenetic protein 6 | Bone morphogenetic protein 5 | Bone morphogenetic protein 4 | Bone morphogenetic protein 2 | Threonine | Research & development--R&D | Anemia | Affinity | Protein-serine/threonine kinase | Surface plasmon resonance | Mutation | Receptor mechanisms | Bone morphogenetic protein 9 | Bone morphogenetic protein 7 | Index Medicus | Research & development | R&D
Journal Article
Developmental cell, ISSN 1534-5807, 06/2013, Volume 25, Issue 6, pp. 636 - 644
Journal Article
PloS one, ISSN 1932-6203, 09/2011, Volume 6, Issue 9, pp. e25021 - e25021
Background: Hub proteins are connected through binding interactions to many other proteins... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Luciferases - metabolism | Oligonucleotide Array Sequence Analysis | Humans | Gene Expression Profiling | Smad3 Protein - metabolism | Immunoenzyme Techniques | DNA-Binding Proteins - metabolism | Smad3 Protein - genetics | Kidney - metabolism | Myoblasts - metabolism | Smad4 Protein - genetics | Smad2 Protein - genetics | Myoblasts - cytology | Protein Interaction Domains and Motifs | Real-Time Polymerase Chain Reaction | Biomarkers - metabolism | Proto-Oncogene Proteins - metabolism | Signal Transduction | RNA, Messenger - genetics | Trans-Activators | Cells, Cultured | Gene Expression Regulation | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Proto-Oncogene Proteins - genetics | Kidney - cytology | DNA-Binding Proteins - genetics | Mutation - genetics | Reverse Transcriptase Polymerase Chain Reaction | Nerve Tissue Proteins - genetics | Smad4 Protein - metabolism | Blotting, Western | Nerve Tissue Proteins - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Transforming Growth Factor beta - genetics | Protein Conformation | Smad3 Protein - chemistry | Mice | Ubiquitin-Protein Ligases - genetics | Transforming Growth Factor beta - metabolism | Amino acids | Bone morphogenetic proteins | Cellular signal transduction | Genetic aspects | Binding proteins | Transforming growth factors | Gene expression | Protein-protein interactions | Protein binding | Transcription factors | Laboratories | Genes | Transforming growth factor-b | Oncology | Smad3 protein | Kinases | Smad4 protein | Proteins | Signal transduction | Cell growth | Reporter gene | Cooperation | Spots | Interleukin 1 | Stress response | Growth factors | Public health | Binding | Medical research | Interleukin 11 | Gelatinase B | Mutants | Medicine | Signaling | Mutagenesis | Lymphomas | Mutation | Protein interaction | Binding sites | Cancer | Apoptosis | Index Medicus | Transduction
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 07/2008, Volume 105, Issue 29, pp. 10073 - 10078
Journal Article