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Nature Genetics, ISSN 1061-4036, 11/2013, Volume 45, Issue 11, pp. 1309 - 1321
Journal Article
Journal Article
Blood, ISSN 0006-4971, 08/2008, Volume 112, Issue 4, pp. 1503 - 1509
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2010, Volume 107, Issue 44, pp. 18886 - 18891
The proper function of the bone morphogenic protein (BMP) pathway during embryonic development and organ maintenance requires its communication with other... 
Receptors | Phosphorylation | Plasmids | Neurons | Ubiquitins | Antibodies | Gene expression regulation | Embryos | Progenitor cells | Cells | PATHWAYS | NERVOUS-SYSTEM | TRANSCRIPTIONAL ACTIVATION | TGF-BETA | BMP | MULTIDISCIPLINARY SCIENCES | E3 UBIQUITIN LIGASES | RECEPTORS | CELL-TYPES | DORSAL SPINAL-CORD | FAMILY | Phosphorylation - physiology | Mitogen-Activated Protein Kinase Kinases - genetics | Cell Proliferation | Stem Cells - metabolism | Wnt Proteins - metabolism | Embryo, Mammalian - metabolism | Receptors, Retinoic Acid - genetics | Mitogen-Activated Protein Kinase Kinases - metabolism | Bone Morphogenetic Proteins - metabolism | Wnt Proteins - genetics | Tretinoin - metabolism | Smad1 Protein - genetics | Cell Cycle Proteins - genetics | Ubiquitination - physiology | Nuclear Proteins - genetics | Bone Morphogenetic Proteins - genetics | Cell Differentiation - physiology | Epidermal Growth Factor - genetics | Cell Cycle Proteins - metabolism | Ubiquitin-Protein Ligases - metabolism | Embryonic Development - physiology | Epidermal Growth Factor - metabolism | Nuclear Proteins - metabolism | Receptors, Retinoic Acid - metabolism | Glycogen Synthase Kinase 3 - metabolism | Chick Embryo | Proteasome Endopeptidase Complex - genetics | Animals | Glycogen Synthase Kinase 3 - genetics | Embryo, Mammalian - cytology | Cell Line, Tumor | Smad1 Protein - metabolism | Signal Transduction - physiology | Mice | Proteasome Endopeptidase Complex - metabolism | Neural Tube - embryology | Ubiquitin-Protein Ligases - genetics | Physiological aspects | Bone morphogenetic proteins | Research | Properties | Proteolysis | Tretinoin | Cell proliferation | Fibroblast growth factor | Pattern formation | Smad protein | Transcription | Wnt protein | Retinoic acid receptors | proteasomes | MAP kinase | Signal transduction | Embryogenesis | Neural tube | ubiquitination | GADD45 protein | Neural stem cells | Differentiation | Retinoic acid | Ubiquitin-protein ligase | Communication | Biological Sciences
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 02/2015, Volume 466, Issue 1, pp. 55 - 68
Journal Article
Molecular and Cellular Biology, ISSN 0270-7306, 07/2012, Volume 32, Issue 14, pp. 2904 - 2916
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0166382
There is confusion about the role that IFN-alpha plays in the pathogenesis of pulmonary arterial hypertension (PAH) with different investigators reporting a... 
ENDOPLASMIC-RETICULUM STRUCTURE | CONTACT SITES | CELLS | INTERFERON | PULMONARY ARTERIAL-HYPERTENSION | MULTIDISCIPLINARY SCIENCES | GOLGI-APPARATUS | NITRIC-OXIDE | ANTIVIRAL ACTIVITY | RECEPTOR | ENDOCYTOSIS | Smad8 Protein - genetics | rab5 GTP-Binding Proteins - genetics | Bone Morphogenetic Protein 4 - genetics | Humans | Bone Morphogenetic Protein 4 - metabolism | rab5 GTP-Binding Proteins - metabolism | Endosomes - metabolism | Pulmonary Artery - metabolism | Interferon-alpha - genetics | Smad5 Protein - metabolism | HEK293 Cells | Smad1 Protein - genetics | Growth Differentiation Factors - genetics | Transcription, Genetic | Endocytosis - genetics | Smad5 Protein - genetics | Vesicular Transport Proteins | Interferon-alpha - metabolism | Signal Transduction | Endothelial Cells - metabolism | Hypertension, Pulmonary - genetics | Clathrin - genetics | Hypertension, Pulmonary - metabolism | Clathrin - metabolism | Growth Differentiation Factors - metabolism | Smad1 Protein - metabolism | Smad8 Protein - metabolism | Endothelial Cells - pathology | Myxovirus Resistance Proteins - genetics | Myxovirus Resistance Proteins - metabolism | Pulmonary Artery - pathology | Bone morphogenetic proteins | Clathrin | Genetic aspects | Genetic transcription | Pulmonary hypertension | Transcription | Pathogenesis | Proteins | α-Interferon | Nocodazole | Stimulators | Endocytosis | Vascular diseases | Rodents | Paclitaxel | Cell cycle | Immunoelectron microscopy | Growth factors | Hypertension | Bone morphogenetic protein 4 | Bone morphogenetic protein receptor type II | Caveolin | Tubules | Endothelial cells | Mutants | Signaling | Hypotheses | Inhibitors | Microscopy | Nitric oxide | Microtubules | Dynamin | Hypoxia | Mutation | Immunofluorescence | Endoplasmic reticulum | Prostate | Bone morphogenetic protein 9 | Endosomes | Guanosinetriphosphatase
Journal Article
Nature Cell Biology, ISSN 1465-7392, 05/2009, Volume 11, Issue 5, pp. 637 - 643
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0166984
Birth defects are among the leading causes of infant mortality and contribute substantially to illness and long-term disability. Defects in Bone Morphogenetic... 
BRANCHIAL ARCH | DLX GENES | HEAD SKELETON | ALAGILLE-SYNDROME | DOWNS-SYNDROME | MULTIDISCIPLINARY SCIENCES | AURICULOCONDYLAR SYNDROME | LEFT-RIGHT ASYMMETRY | REPEAT PROTEIN | HUMAN JAGGED1 | NEURAL CREST CELLS | Jagged-1 Protein - metabolism | Zebrafish - embryology | Intercellular Signaling Peptides and Proteins - metabolism | Somites - embryology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nuclear Proteins - biosynthesis | Smad5 Protein - metabolism | Smad1 Protein - genetics | Smad5 Protein - genetics | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | Zebrafish Proteins - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - genetics | Endothelin-1 - genetics | Endothelin-1 - metabolism | Zebrafish Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Repressor Proteins - genetics | Jagged-1 Protein - genetics | Zebrafish - genetics | Body Patterning - physiology | Animals | Transforming Growth Factor beta - genetics | Facial Bones - enzymology | Smad1 Protein - metabolism | Signal Transduction - physiology | Zebrafish Proteins - genetics | Transforming Growth Factor beta - metabolism | Bone morphogenetic proteins | Genetic aspects | Research | Craniofacial abnormalities | Neural crest | Pattern formation | Jaw | Transcription factors | Endothelin | Arches | Congenital defects | Alagille syndrome | Genomics | Transforming growth factor-b | Genomes | Somites | Kinases | Defects | Proteins | Cartilage | Signal transduction | Pathways | Growth factors | Territory | Patterning | Mandible | Interference | Craniofacial syndromes | Zebrafish | Infant mortality | Birth defects | Endothelin 1 | Gene expression | Embryos | Mutants | Cleft lip/palate | Craniofacial growth | Signaling | Scaffolding | In vivo methods and tests | Notch protein
Journal Article
Journal Article
Cell, ISSN 0092-8674, 2005, Volume 123, Issue 6, pp. 1147 - 1160
Embryos have the ability to self-regulate and regenerate normal structures after being sectioned in half. How is such a morphogenetic field established? We... 
Body Patterning - drug effects | Metalloendopeptidases - genetics | Organizers, Embryonic - physiology | Organizers, Embryonic - transplantation | Central Nervous System - metabolism | Bone Morphogenetic Proteins - physiology | Xenopus Proteins - genetics | Follistatin - genetics | Glycoproteins - metabolism | Metalloendopeptidases - metabolism | Oligodeoxyribonucleotides, Antisense - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Central Nervous System - embryology | Intercellular Signaling Peptides and Proteins - metabolism | Membrane Proteins - physiology | Base Sequence | Carrier Proteins - administration & dosage | Tissue Transplantation | Xenopus laevis - genetics | Phosphorylation - drug effects | Intercellular Signaling Peptides and Proteins - administration & dosage | Bone Morphogenetic Proteins - genetics | Glycoproteins - genetics | Bone Morphogenetic Protein 4 | Bone Morphogenetic Proteins - administration & dosage | Xenopus laevis - embryology | Microinjections | Bone Morphogenetic Protein 2 | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Transforming Growth Factor beta - physiology | Metalloendopeptidases - administration & dosage | Bone Morphogenetic Protein Receptors, Type I - metabolism | Glycoproteins - administration & dosage | Body Patterning - physiology | Proteins - genetics | Carrier Proteins - genetics | Animals | Transforming Growth Factor beta - genetics | Organizers, Embryonic - metabolism | Xenopus Proteins - physiology | Smad1 Protein - metabolism | Xenopus Proteins - metabolism | Mutation | Xenopus laevis - physiology | Bone Morphogenetic Protein 7 | Morphogenesis | Genetic research | Research | Genetic regulation | Ubiquitin-proteasome system | Bone morphogenetic proteins
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 11/2017, Volume 31, Issue 11, pp. 4720 - 4733
Before the onset of sprouting angiogenesis, the endothelium is prepatterned for the positioning of tip and stalk cells. Both cell identities are not static, as... 
cell migration | ALK2 | ALK3 | p38 MAPK | SMAD1/5 | MIGRATION | ACTIVATION | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | NOTCH | CANCER | ALK1 | CELL BIOLOGY | ENDOTHELIAL-CELLS | BIOLOGY | GROWTH-FACTOR | EXPRESSION | MAP Kinase Signaling System - physiology | Human Umbilical Vein Endothelial Cells - metabolism | Humans | Vascular Endothelial Growth Factor A - metabolism | Vascular Endothelial Growth Factor A - genetics | Vascular Endothelial Growth Factor Receptor-2 - genetics | HSP27 Heat-Shock Proteins - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Bone Morphogenetic Protein 6 - genetics | Smad5 Protein - metabolism | Bone Morphogenetic Protein 2 - metabolism | Human Umbilical Vein Endothelial Cells - cytology | Smad1 Protein - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Smad5 Protein - genetics | Bone Morphogenetic Protein 2 - genetics | Intercellular Signaling Peptides and Proteins - genetics | Bone Morphogenetic Protein Receptors, Type I - genetics | Vascular Endothelial Growth Factor Receptor-2 - metabolism | p38 Mitogen-Activated Protein Kinases - genetics | Activin Receptors, Type I - metabolism | Bone Morphogenetic Protein Receptors, Type I - metabolism | Activin Receptors, Type I - genetics | Neovascularization, Physiologic - physiology | Bone Morphogenetic Protein 6 - metabolism | HSP27 Heat-Shock Proteins - metabolism | Smad1 Protein - metabolism | Complex formation | Genes | Clinical trials | Cell adhesion & migration | Proteins | Angiogenesis | Signal transduction | Receptors | Pathways | Vascular endothelial growth factor | Protein-tyrosine kinase | Enhancer-of-split protein | Bone morphogenetic protein 6 | Tyrosine | Medical research | Bone morphogenetic protein 2 | Heat shock proteins | Gene expression | Spheroids | Endothelial cells | Bone morphogenetic protein receptor type I | Endothelium | Signaling | Antiangiogenics | Hsp27 protein | Bone | Activin | Cell migration | Heat shock | SMAD1 | Research
Journal Article
Development (Cambridge), ISSN 0950-1991, 08/2013, Volume 140, Issue 16, pp. 3348 - 3359
Journal Article