X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
animals (368) 368
index medicus (358) 358
humans (357) 357
smad2 protein - metabolism (295) 295
mice (224) 224
smad2 protein (210) 210
signal transduction (208) 208
tgf-beta (185) 185
phosphorylation (169) 169
smad3 protein - metabolism (157) 157
female (154) 154
male (151) 151
cells, cultured (141) 141
transforming growth factor beta - metabolism (134) 134
cell biology (132) 132
growth-factor-beta (131) 131
smad2 protein - genetics (124) 124
expression (118) 118
biochemistry & molecular biology (102) 102
fibrosis (101) 101
rats (96) 96
signal transduction - drug effects (93) 93
cell line (92) 92
gene expression (85) 85
oncology (85) 85
activation (82) 82
cell line, tumor (81) 81
proteins (80) 80
smad3 protein (80) 80
transforming growth factor beta1 - metabolism (78) 78
transforming growth factor beta - pharmacology (73) 73
smad2 protein - biosynthesis (70) 70
dna-binding proteins - metabolism (69) 69
smad2 (69) 69
collagen (65) 65
trans-activators - metabolism (65) 65
fibroblasts - metabolism (63) 63
receptors, transforming growth factor beta - metabolism (62) 62
smad3 protein - genetics (62) 62
transforming growth factors (60) 60
immunohistochemistry (57) 57
smad (56) 56
growth factors (55) 55
adult (54) 54
blotting, western (53) 53
phosphorylation - drug effects (53) 53
apoptosis (52) 52
transforming growth factor beta - physiology (52) 52
middle aged (51) 51
cell proliferation (50) 50
gene expression regulation (50) 50
transforming growth factor beta - genetics (50) 50
transforming growth factor beta1 - pharmacology (50) 50
kinases (49) 49
smad4 protein (49) 49
cancer (48) 48
dna-binding proteins - genetics (48) 48
fibroblasts (48) 48
signal transduction - physiology (48) 48
dna-binding proteins - biosynthesis (46) 46
rna, messenger - genetics (46) 46
receptor (45) 45
rna, messenger - metabolism (45) 45
reverse transcriptase polymerase chain reaction (44) 44
bone morphogenetic proteins (43) 43
differentiation (43) 43
gene expression regulation - drug effects (43) 43
gene-expression (43) 43
inhibition (43) 43
rats, sprague-dawley (43) 43
rna, messenger - biosynthesis (43) 43
trans-activators - genetics (43) 43
cell proliferation - drug effects (42) 42
mice, inbred c57bl (42) 42
tgf-β (42) 42
trans-activators - biosynthesis (42) 42
research article (41) 41
rodents (41) 41
transforming growth factor beta - biosynthesis (41) 41
fibroblasts - drug effects (40) 40
transfection (40) 40
collagen - biosynthesis (39) 39
immunology (39) 39
mice, knockout (39) 39
up-regulation (39) 39
article (38) 38
proliferation (38) 38
rna interference (38) 38
receptors, transforming growth factor beta - genetics (37) 37
activin (36) 36
disease models, animal (36) 36
gene (36) 36
down-regulation (35) 35
medicine (35) 35
multidisciplinary sciences (35) 35
transcription (35) 35
cell differentiation (34) 34
growth (34) 34
signaling (34) 34
cells (33) 33
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Immunity, ISSN 1074-7613, 09/2014, Volume 41, Issue 3, pp. 427 - 439
Journal Article
Cancer Science, ISSN 1347-9032, 03/2017, Volume 108, Issue 3, pp. 419 - 426
Vasohibin‐2 (VASH2) is a homolog of VASH1, an endothelium‐derived angiogenesis inhibitor. Vasohibin‐2 is mainly expressed in cancer cells, and has been... 
TGF‐β | ALK5 | vasohibin‐2 | ovarian cancer | EMT | TGF-β | vasohibin-2 | PROTEIN | REPRESSES E-CADHERIN | TUMOR ANGIOGENESIS | R-I | FAMILY | TGF-beta | ONCOLOGY | ENDOTHELIUM | ROLES | INHIBITOR | BINDING | Angiogenic Proteins - genetics | RNA, Small Interfering - genetics | Fibronectins - biosynthesis | Humans | Ovarian Neoplasms - pathology | Smad3 Protein - metabolism | Snail Family Transcription Factors - biosynthesis | Epithelial-Mesenchymal Transition - genetics | Zinc Finger E-box Binding Homeobox 2 | Cadherins - biosynthesis | Ovarian Neoplasms - genetics | Phosphorylation - genetics | RNA Interference | Female | Matrix Metalloproteinase 2 - biosynthesis | Cell Proliferation - genetics | Homeodomain Proteins - biosynthesis | Smad2 Protein - metabolism | Signal Transduction - genetics | Protein-Serine-Threonine Kinases - biosynthesis | Plasminogen Activator Inhibitor 1 - biosynthesis | Receptors, Transforming Growth Factor beta - biosynthesis | Repressor Proteins - biosynthesis | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Transforming Growth Factor beta - metabolism | Phosphorylation | Mesenchyme | Laboratories | Genes | Cytology | Smad3 protein | Kinases | Fibronectin | Ovarian cancer | Proteins | Liver cancer | Angiogenesis | Smad2 protein | Growth factors | Immunoglobulins | Cytokines | Endothelium | Gelatinase A | MicroRNAs | Adenoviruses | Morphology | Plasminogen activator inhibitors | Angiogenesis inhibitors | Activin | Cell migration | Original
Journal Article
Cell Cycle, ISSN 1538-4101, 06/2010, Volume 9, Issue 12, pp. 2423 - 2433
Loss of stromal caveolin 1 (Cav-1) is a novel biomarker for cancer-associated fibroblasts that predicts poor clinical outcome in breast cancer and DCIS... 
Binding | Proteins | Landes | Calcium | Bioscience | Biology | Cell | Cycle | Cancer | Organogenesis | Caveolin-1 | Lysosomal degradation | Chloroquine | Myofibroblast | Tumor stroma | TGFbeta signaling | Cancer associated fibroblasts | Autophagy | ACTIVATION | autophagy | TGF-BETA | lysosomal degradation | myofibroblast | SYSTEMIC-SCLEROSIS | cancer associated fibroblasts | CELL BIOLOGY | chloroquine | caveolin-1 | GROWTH | GENE-EXPRESSION | STROMAL FIBROBLASTS | VIMENTIN EXPRESSION | tumor stroma | TENASCIN | MMP-9 | PROGRESSION | Prognosis | Extracellular Matrix Proteins - biosynthesis | Coculture Techniques | Humans | Carcinoma, Intraductal, Noninfiltrating - metabolism | Transforming Growth Factor beta - biosynthesis | Autophagy - drug effects | Actins - genetics | Breast Neoplasms - metabolism | Chloroquine - pharmacology | Smad2 Protein - biosynthesis | Vimentin - genetics | Female | Microfilament Proteins - genetics | Fibroblasts - metabolism | Actins - biosynthesis | Calcium-Binding Proteins - biosynthesis | Vimentin - biosynthesis | Extracellular Matrix Proteins - genetics | Caveolin 1 - genetics | Caveolin 1 - metabolism | Microfilament Proteins - biosynthesis | Phenotype | Cell Line, Tumor | Biomarkers, Tumor - genetics | Transforming Growth Factor beta - metabolism | Biomarkers, Tumor - biosynthesis | Calcium-Binding Proteins - genetics
Journal Article
Cytokine, ISSN 1043-4666, 10/2013, Volume 64, Issue 1, pp. 35 - 38
The role of transforming growth factor-β1 (TGFβ1) and Smad signalling has not been established in psoriasis treatment. We aimed to investigate the effect of... 
Smads | Balneophototherapy | Balneotherapy | Transforming growth factor | Salt water baths | HUMAN SKIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | EQUIVALENTS | IMMUNOLOGY | CELL BIOLOGY | IRRADIATION | MESSENGER-RNA | PATHWAY | EXPRESSION | Receptors, Transforming Growth Factor beta - genetics | Humans | Transforming Growth Factor beta1 - metabolism | Smad3 Protein - metabolism | Sodium Chloride - therapeutic use | RNA, Messenger - biosynthesis | Smad2 Protein - biosynthesis | Smad3 Protein - genetics | Smad4 Protein - genetics | Smad2 Protein - genetics | Psoriasis - metabolism | Smad4 Protein - biosynthesis | Smad7 Protein - genetics | Transforming Growth Factor beta1 - biosynthesis | Psoriasis - therapy | Smad7 Protein - metabolism | Cell Line | Epidermis - metabolism | Protein Precursors - genetics | Signal Transduction | Ultraviolet Therapy | Smad2 Protein - metabolism | Transforming Growth Factor beta1 - genetics | Smad4 Protein - metabolism | Protein Precursors - metabolism | Receptors, Transforming Growth Factor beta - biosynthesis | Minichromosome Maintenance Complex Component 7 - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Keratinocytes - metabolism | Protein Precursors - biosynthesis | Minichromosome Maintenance Complex Component 7 - genetics | Minichromosome Maintenance Complex Component 7 - biosynthesis | Smad7 Protein - biosynthesis | Smad Proteins - metabolism | Smad3 Protein - biosynthesis
Journal Article
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 11/2014, Volume 16, Issue 12, pp. 1257 - 1264
Journal Article
Oncogene, ISSN 0950-9232, 06/2014, Volume 33, Issue 26, pp. 3432 - 3440
Biomarkers that predict disease progression might assist the development of better therapeutic strategies for aggressive cancers, such as ovarian cancer. Here,... 
ovarian carcinoma | COL11A1 | tumor progression | TGF-BETA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION PROFILES | ETS-1 TRANSCRIPTION FACTOR | MICROARRAY ANALYSIS | CELL BIOLOGY | MATRIX METALLOPROTEINASES | HEPATOCELLULAR-CARCINOMA | CLEAR-CELL | ONCOLOGY | GENETICS & HEREDITY | SQUAMOUS-CELL CARCINOMA | EXTRACELLULAR-MATRIX | IN-SITU | Neoplasm Transplantation | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Transplantation, Heterologous | Gene Expression Profiling | Ovarian Neoplasms - mortality | Promoter Regions, Genetic - genetics | Ovarian Neoplasms - genetics | RNA, Messenger - biosynthesis | Smad2 Protein - biosynthesis | Collagen Type XI - genetics | RNA Interference | Female | Transforming Growth Factor beta1 - pharmacology | Neoplasm Invasiveness | Smad2 Protein - metabolism | Matrix Metalloproteinase 3 - metabolism | Survival Rate | Treatment Outcome | Signal Transduction - genetics | Mice, SCID | Disease Progression | Matrix Metalloproteinase 3 - biosynthesis | Animals | Cell Line, Tumor | Proto-Oncogene Protein c-ets-1 - genetics | Neoplasm Recurrence, Local - genetics | Biomarkers, Tumor - genetics | Mice | RNA, Small Interfering | Development and progression | Genetic aspects | Cellular signal transduction | Properties | Collagen | Ovarian cancer | Tumorigenesis | Clinical outcomes
Journal Article
Journal Article