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Immunity, ISSN 1074-7613, 09/2014, Volume 41, Issue 3, pp. 427 - 439
Journal Article
Cancer Science, ISSN 1347-9032, 03/2017, Volume 108, Issue 3, pp. 419 - 426
Vasohibin‐2 (VASH2) is a homolog of VASH1, an endothelium‐derived angiogenesis inhibitor. Vasohibin‐2 is mainly expressed in cancer cells, and has been... 
TGF‐β | ALK5 | vasohibin‐2 | ovarian cancer | EMT | TGF-β | vasohibin-2 | PROTEIN | REPRESSES E-CADHERIN | TUMOR ANGIOGENESIS | R-I | FAMILY | TGF-beta | ONCOLOGY | ENDOTHELIUM | ROLES | INHIBITOR | BINDING | Angiogenic Proteins - genetics | RNA, Small Interfering - genetics | Fibronectins - biosynthesis | Humans | Ovarian Neoplasms - pathology | Smad3 Protein - metabolism | Snail Family Transcription Factors - biosynthesis | Epithelial-Mesenchymal Transition - genetics | Zinc Finger E-box Binding Homeobox 2 | Cadherins - biosynthesis | Ovarian Neoplasms - genetics | Phosphorylation - genetics | RNA Interference | Female | Matrix Metalloproteinase 2 - biosynthesis | Cell Proliferation - genetics | Homeodomain Proteins - biosynthesis | Smad2 Protein - metabolism | Signal Transduction - genetics | Protein-Serine-Threonine Kinases - biosynthesis | Plasminogen Activator Inhibitor 1 - biosynthesis | Receptors, Transforming Growth Factor beta - biosynthesis | Repressor Proteins - biosynthesis | Cell Line, Tumor | Neovascularization, Pathologic - genetics | Transforming Growth Factor beta - metabolism | Phosphorylation | Mesenchyme | Laboratories | Genes | Cytology | Smad3 protein | Kinases | Fibronectin | Ovarian cancer | Proteins | Liver cancer | Angiogenesis | Smad2 protein | Growth factors | Immunoglobulins | Cytokines | Endothelium | Gelatinase A | MicroRNAs | Adenoviruses | Morphology | Plasminogen activator inhibitors | Angiogenesis inhibitors | Activin | Cell migration | Original
Journal Article
Cancer Research, ISSN 0008-5472, 11/2011, Volume 71, Issue 21, pp. 6718 - 6727
Journal Article
Cytokine, ISSN 1043-4666, 10/2013, Volume 64, Issue 1, pp. 35 - 38
The role of transforming growth factor-β1 (TGFβ1) and Smad signalling has not been established in psoriasis treatment. We aimed to investigate the effect of... 
Smads | Balneophototherapy | Balneotherapy | Transforming growth factor | Salt water baths | HUMAN SKIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | EQUIVALENTS | IMMUNOLOGY | CELL BIOLOGY | IRRADIATION | MESSENGER-RNA | PATHWAY | EXPRESSION | Receptors, Transforming Growth Factor beta - genetics | Humans | Transforming Growth Factor beta1 - metabolism | Smad3 Protein - metabolism | Sodium Chloride - therapeutic use | RNA, Messenger - biosynthesis | Smad2 Protein - biosynthesis | Smad3 Protein - genetics | Smad4 Protein - genetics | Smad2 Protein - genetics | Psoriasis - metabolism | Smad4 Protein - biosynthesis | Smad7 Protein - genetics | Transforming Growth Factor beta1 - biosynthesis | Psoriasis - therapy | Smad7 Protein - metabolism | Cell Line | Epidermis - metabolism | Protein Precursors - genetics | Signal Transduction | Ultraviolet Therapy | Smad2 Protein - metabolism | Transforming Growth Factor beta1 - genetics | Smad4 Protein - metabolism | Protein Precursors - metabolism | Receptors, Transforming Growth Factor beta - biosynthesis | Minichromosome Maintenance Complex Component 7 - metabolism | Receptors, Transforming Growth Factor beta - metabolism | Keratinocytes - metabolism | Protein Precursors - biosynthesis | Minichromosome Maintenance Complex Component 7 - genetics | Minichromosome Maintenance Complex Component 7 - biosynthesis | Smad7 Protein - biosynthesis | Smad Proteins - metabolism | Smad3 Protein - biosynthesis
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 2011, Volume 6, Issue 7, p. e21679
Chondrogenic differentiation of mesenchymal stem cells (MSCs) is accurately regulated by essential transcription factors and signaling cascades. However, the... 
ACTIVATION | SMAD3 | MESSENGER-RNA EXPRESSION | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | TRANSCRIPTION | PHENOTYPE | NUCLEAR EXPORT | DICER | CULTURE | CARTILAGE | SOX9 Transcription Factor - metabolism | Transforming Growth Factor beta3 - pharmacology | Cell Line | Mesenchymal Stromal Cells - drug effects | Chondrogenesis - drug effects | Chondrogenesis - genetics | 3' Untranslated Regions - genetics | Mesenchymal Stromal Cells - metabolism | Genes, Reporter - genetics | MicroRNAs - metabolism | Down-Regulation - drug effects | Down-Regulation - genetics | Luciferases - genetics | Cell Differentiation - genetics | Mesenchymal Stromal Cells - cytology | Animals | Cell Differentiation - drug effects | Base Sequence | Mice | MicroRNAs - genetics | SOX9 Transcription Factor - genetics | MicroRNA | Genes | Luciferase | Stem cells | Bone morphogenetic proteins | Protein biosynthesis | DNA binding proteins | Genetic transcription | Transforming growth factors | Protein binding | Transcription factors | Mesenchyme | Laboratories | Collagen (type II) | Sox9 protein | Homeostasis | Stem cell transplantation | Smooth muscle | Kinases | Cartilage oligomeric matrix protein | Proteins | Cartilage | Genotype & phenotype | Allografts | Reporter gene | Collagen (type IX) | Cascades | Bone marrow | Matrix protein | Chondrogenesis | Growth factors | Transforming growth factor-b1 | MiRNA | Gene expression | Ribonucleic acid--RNA | Biological activity | Studies | Biomechanics | Signaling | High mobility group proteins | Overexpression | 3' Untranslated regions | Protein synthesis | MicroRNAs | Protein expression | Aggrecan | Differentiation | Binding sites | Apoptosis | RNA | Ribonucleic acid
Journal Article
Journal Article
Journal Article
Life Sciences, ISSN 0024-3205, 04/2015, Volume 127, pp. 59 - 65
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2014, Volume 9, Issue 12, pp. e114287 - e114287
Diabetic nephropathy (DN) is characterized by proliferation of mesangial cells, mesangial expansion, hypertrophy and extracellular matrix accumulation.... 
KIDNEY-DISEASE | FIBROSIS | GLOMERULOSCLEROSIS | TGF-BETA | PHOSPHORYLATION | MULTIDISCIPLINARY SCIENCES | GROWTH | HIGH GLUCOSE | IMMUNOMODULATOR AS101 | PHOSPHOINOSITIDE 3-KINASE | RENAL HYPERTROPHY | Oncogene Protein v-akt - biosynthesis | Diabetes Mellitus, Experimental - drug therapy | Diabetic Nephropathies - pathology | Phosphorylation | Gene Expression - drug effects | Diabetes Mellitus, Experimental - genetics | PTEN Phosphohydrolase - biosynthesis | Diabetic Nephropathies - drug therapy | Rats | Blood Glucose | Diabetic Nephropathies - genetics | Ethylenes - administration & dosage | Transforming Growth Factor beta - biosynthesis | Mesangial Cells - drug effects | Phosphatidylinositol 3-Kinases - genetics | Smad3 Protein - genetics | Animals | Signal Transduction - drug effects | Mesangial Cells - pathology | Oncogene Protein v-akt - genetics | Diabetes Mellitus, Experimental - pathology | Phosphatidylinositol 3-Kinases - biosynthesis | Smad3 Protein - biosynthesis | Prevention | Blood sugar | Collagen | Analysis | Diabetic nephropathies | Development and progression | Transforming growth factors | TOR protein | Cell proliferation | Animal models | Nephrology | Streptozocin | Leukemia | AKT protein | Smad3 protein | Glucose | Kinases | Accumulation | Proteins | Signal transduction | Hyperglycemia | Cell growth | Immunology | Rodents | Cell cycle | Mesangial cells | Biocompatibility | Extracellular matrix | Life sciences | Inhibition | FOXO3 protein | Urine | Hypertension | Kidneys | Diabetes mellitus | Crosslinking | Pharmacology | 1-Phosphatidylinositol 3-kinase | Nephropathy | Kidney diseases | Diabetes | PTEN protein | Hypertrophy | Proteinuria | Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2007, Volume 132, Issue 3, pp. 994 - 1008
Background & Aims: Interleukin (IL)-15 delivers signals that drive chronic inflammation in several diseases, including celiac disease. Smad3–transforming... 
Gastroenterology and Hepatology | RHEUMATOID-ARTHRITIS | GROWTH-FACTOR-BETA | NATURAL-KILLER | HUMAN DERMAL FIBROBLASTS | GENE-EXPRESSION | IL-15R-ALPHA CHAIN | NECROSIS-FACTOR-ALPHA | TNF-ALPHA | GASTROENTEROLOGY & HEPATOLOGY | INTRAEPITHELIAL LYMPHOCYTES | HUMAN T-CELLS | Up-Regulation | Intestinal Mucosa - metabolism | Phosphorylation | Humans | Middle Aged | Transforming Growth Factor beta1 - metabolism | Immunity, Mucosal | JNK Mitogen-Activated Protein Kinases - metabolism | Smad3 Protein - metabolism | Interleukin-15 - biosynthesis | Intestinal Mucosa - drug effects | RNA, Messenger - biosynthesis | Cell Nucleus - metabolism | T-Lymphocytes - metabolism | Time Factors | Celiac Disease - immunology | Intestinal Mucosa - immunology | T-Lymphocytes - drug effects | Adult | Transcription, Genetic | Active Transport, Cell Nucleus | Interferon-gamma - genetics | Smad7 Protein - genetics | Organ Culture Techniques | Transforming Growth Factor beta1 - pharmacology | Interleukin-2 - metabolism | Homeodomain Proteins - biosynthesis | Celiac Disease - genetics | Cells, Cultured | Homeostasis - immunology | Repressor Proteins - genetics | Homeodomain Proteins - genetics | Celiac Disease - pathology | Interleukin-15 - pharmacology | Repressor Proteins - biosynthesis | Tristetraprolin - genetics | Signal Transduction - drug effects | Tristetraprolin - biosynthesis | T-Lymphocytes - immunology | Aged | Enzyme Activation | Smad7 Protein - biosynthesis | Celiac Disease - metabolism | Interferon-gamma - biosynthesis | Intestinal Mucosa - pathology
Journal Article