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Oncogene, ISSN 0950-9232, 12/2012, Volume 31, Issue 50, pp. 5162 - 5171
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 08/2010, Volume 207, Issue 8, pp. 1589 - 1597
Uncontrolled extracellular matrix production by fibroblasts in response to tissue injury contributes to fibrotic diseases, such as idiopathic pulmonary... 
MEDICINE, RESEARCH & EXPERIMENTAL | RESPONSES | PHOSPHATASE | INJURY | TENSIN HOMOLOG | MECHANISMS | GROWTH-FACTOR | IMMUNOLOGY | MYOFIBROBLAST DIFFERENTIATION | EXPRESSION | CANCER | MICRORNA | Oligonucleotides - genetics | Pulmonary Fibrosis - therapy | Idiopathic Pulmonary Fibrosis - genetics | Gene Expression - drug effects | Gene Expression - genetics | Humans | Actins - metabolism | MicroRNAs - metabolism | Pulmonary Fibrosis - genetics | Idiopathic Pulmonary Fibrosis - metabolism | Actins - genetics | Antisense Elements (Genetics) - therapeutic use | Collagen - genetics | Lung - metabolism | Phosphorylation - drug effects | Smad7 Protein - genetics | Extracellular Matrix Proteins - metabolism | Transforming Growth Factor beta1 - pharmacology | Fibroblasts - metabolism | Smad7 Protein - metabolism | Cell Line | Lung - pathology | Extracellular Matrix Proteins - genetics | Mice, Inbred C57BL | Smad2 Protein - metabolism | Mice, Transgenic | Pulmonary Fibrosis - pathology | Transforming Growth Factor beta1 - genetics | Fibroblasts - pathology | Fibronectins - metabolism | Collagen - metabolism | Animals | Fibroblasts - drug effects | Antisense Elements (Genetics) - genetics | Idiopathic Pulmonary Fibrosis - pathology | Pulmonary Fibrosis - chemically induced | Bleomycin - pharmacology | Fibronectins - genetics | Mice | MicroRNAs - genetics | Index Medicus | Brief Definitive Report
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 03/2012, Volume 18, Issue 3, pp. 429 - U192
Journal Article
Kidney International, ISSN 0085-2538, 12/2013, Volume 84, Issue 6, pp. 1129 - 1144
The TGF-β/Smad3 pathway plays a major role in tissue fibrosis, but the precise mechanisms are not fully understood. Here we identified microRNA miR-433 as an... 
miR-433 | renal fibrosis | TGF-β signaling | microRNA therapy | KIDNEY-DISEASE | TGF-BETA | DIABETIC-NEPHROPATHY | MESENCHYMAL TRANSITION | TGF-beta signaling | GROWTH-FACTOR-BETA | TARGETED DISRUPTION | POLYAMINE DEPLETION | UNILATERAL URETERAL OBSTRUCTION | EPITHELIAL-CELLS | TUBULOINTERSTITIAL FIBROSIS | UROLOGY & NEPHROLOGY | Up-Regulation | Ureteral Obstruction - complications | Kidney - pathology | Transforming Growth Factor beta1 - metabolism | Male | MicroRNAs - metabolism | Smad3 Protein - metabolism | Mice, 129 Strain | Anti-Glomerular Basement Membrane Disease - metabolism | Doxorubicin | Kidney Diseases - genetics | Smad3 Protein - deficiency | Smad3 Protein - genetics | Kidney - metabolism | Transfection | RNA Interference | Time Factors | Smad2 Protein - genetics | Anti-Glomerular Basement Membrane Disease - genetics | Smad7 Protein - genetics | Binding Sites | Disease Models, Animal | Kidney Diseases - metabolism | Smad7 Protein - metabolism | Cell Line | Promoter Regions, Genetic | Signal Transduction | Kidney Diseases - pathology | Kidney Diseases - prevention & control | Anti-Glomerular Basement Membrane Disease - pathology | Mice, Inbred C57BL | Smad2 Protein - metabolism | Rats | Smad2 Protein - deficiency | Transforming Growth Factor beta1 - genetics | Mice, Knockout | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Fibrosis | Mice | MicroRNAs - genetics | Kidney Diseases - etiology | Index Medicus
Journal Article
Neuron, ISSN 0896-6273, 02/2012, Volume 73, Issue 4, pp. 713 - 728
Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that control this... 
TRANSCRIPTION FACTORS | IN-VITRO | MULTIPLE-SCLEROSIS | BONE MORPHOGENETIC PROTEIN | OLIGODENDROCYTE PRECURSOR CELLS | DEMYELINATED LESIONS | MOWAT-WILSON-SYNDROME | DIFFERENTIATION | BETA-CATENIN | CNS MYELINATION | NEUROSCIENCES | Central Nervous System - ultrastructure | Microcephaly - genetics | Oligonucleotide Array Sequence Analysis | Embryo, Mammalian | Homeodomain Proteins - metabolism | Humans | Nerve Tissue Proteins - deficiency | Caspase 3 - metabolism | Ki-67 Antigen - metabolism | Gene Expression Profiling | Green Fluorescent Proteins - genetics | RNA, Messenger - metabolism | Zinc Finger E-box Binding Homeobox 2 | Central Nervous System - physiology | Bone Morphogenetic Proteins - metabolism | Basic Helix-Loop-Helix Transcription Factors - metabolism | Facies | Repressor Proteins - metabolism | Smad7 Protein - metabolism | Animals, Newborn | Basic Helix-Loop-Helix Transcription Factors - genetics | Receptor, Platelet-Derived Growth Factor alpha - metabolism | Hirschsprung Disease - pathology | Intellectual Disability - pathology | Models, Molecular | Smad Proteins - genetics | Oligodendrocyte Transcription Factor 2 | Signal Transduction - genetics | Mice, Knockout | Central Nervous System - cytology | Mice | Optic Nerve - metabolism | Receptor-Interacting Protein Serine-Threonine Kinases - metabolism | Oligodendroglia - metabolism | Immunoprecipitation | Age Factors | Hirschsprung Disease - genetics | Gene Expression Regulation, Developmental - genetics | Intellectual Disability - genetics | Myelin Sheath - metabolism | Cell Differentiation - genetics | Transfection | Microcephaly - pathology | Optic Nerve - embryology | Smad7 Protein - genetics | Optic Nerve - growth & development | Microscopy, Electron, Transmission | Cells, Cultured | Nerve Tissue Proteins - genetics | Organogenesis | Nerve Tissue Proteins - metabolism | Animals | Signal Transduction - physiology | Smad Proteins - metabolism | Medical colleges | Neurosciences | Neurons | Central nervous system | Bone morphogenetic proteins | Universities and colleges | DNA binding proteins | Proteins | Multiple sclerosis | Transcription factors | Rodents | Nervous system | Genomes | Kinases | Gene expression | Index Medicus | Antagonism
Journal Article
Cancer Research, ISSN 0008-5472, 02/2010, Volume 70, Issue 3, pp. 968 - 978
Journal Article
Cardiovascular research, ISSN 0008-6363, 2014, Volume 104, Issue 1, pp. 61 - 71
The overloaded heart remodels by cardiomyocyte hypertrophy and interstitial fibrosis, which contributes to the development of heart failure. Signalling via the... 
miRNA-15 family | TGFβ-pathway | Fibrosis | Hypertrophy | PRESSURE-OVERLOAD | CARDIAC & CARDIOVASCULAR SYSTEMS | TGF-BETA | LEFT-VENTRICULAR FIBROSIS | IMPROVES SURVIVAL | TGF beta-pathway | MIR-15 FAMILY | FAILURE | MYOCARDIAL FIBROSIS | CARDIAC-HYPERTROPHY | GENE-EXPRESSION | TRANSGENIC MICE | Up-Regulation | Receptors, Transforming Growth Factor beta - genetics | Humans | Cercopithecus aethiops | Cardiomegaly - pathology | MicroRNAs - metabolism | Smad3 Protein - metabolism | Case-Control Studies | Cardiomyopathies - genetics | Smad3 Protein - genetics | Cardiomyopathies - physiopathology | Ventricular Remodeling | Transfection | p38 Mitogen-Activated Protein Kinases - metabolism | 3' Untranslated Regions | Smad7 Protein - genetics | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | Smad7 Protein - metabolism | Rats, Transgenic | Signal Transduction | Mice, Inbred C57BL | Protein-Serine-Threonine Kinases - genetics | Cardiomegaly - physiopathology | p38 Mitogen-Activated Protein Kinases - genetics | Cardiomyopathies - pathology | Hep G2 Cells | Animals | Receptors, Transforming Growth Factor beta - metabolism | Cardiomyopathies - metabolism | Myocytes, Cardiac - metabolism | MicroRNAs - genetics | Cardiomegaly - genetics | COS Cells | Transforming Growth Factor beta - metabolism | Cardiomegaly - metabolism | Index Medicus
Journal Article
Blood, ISSN 0006-4971, 08/2008, Volume 112, Issue 4, pp. 1503 - 1509
Journal Article
Science Translational Medicine, ISSN 1946-6234, 07/2016, Volume 8, Issue 348, pp. 348ra98 - 348ra98
Journal Article
Endocrinology, ISSN 0013-7227, 02/2016, Volume 157, Issue 2, pp. 883 - 899
TGFβ has been implicated in preeclampsia, but its intracellular signaling via phosphorylated mothers against decapentaplegic (SMADs) and SMAD-independent... 
HUMAN PLACENTAL TROPHOBLAST | IN-VITRO | BEWO CELLS | ENDOCRINOLOGY & METABOLISM | GENE-EXPRESSION | TRANSFORMING-GROWTH-FACTOR | EPITHELIAL-MESENCHYMAL TRANSITIONS | E-CADHERIN | CELL-LINES | TRANSCRIPTION FACTOR | SYNCYTIAL FUSION | Pre-Eclampsia - genetics | Oncogene Proteins - genetics | Phosphorylation | Cyclin-Dependent Kinase 4 - genetics | Humans | Pregnancy Proteins - genetics | Male | rhoA GTP-Binding Protein - metabolism | Pregnancy Proteins - metabolism | rhoA GTP-Binding Protein - genetics | RNA, Messenger - metabolism | Cyclin E - genetics | Case-Control Studies | Gene Products, env - metabolism | Young Adult | Cell Differentiation - genetics | Smad2 Protein - genetics | Gene Products, env - genetics | Adult | Female | Pre-Eclampsia - metabolism | Nuclear Proteins - genetics | Smad7 Protein - genetics | Real-Time Polymerase Chain Reaction | Infant, Newborn | Smad7 Protein - metabolism | Cell Proliferation - genetics | Trophoblasts - metabolism | Signal Transduction | Oncogene Proteins - metabolism | Smad2 Protein - metabolism | Ubiquitin-Protein Ligases - metabolism | Nuclear Proteins - metabolism | Transcription Factors - genetics | Cyclin-Dependent Kinase 4 - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Gestational Age | Placenta - metabolism | Pregnancy | Transcription Factors - metabolism | Transforming Growth Factor beta - genetics | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Cyclin E - metabolism | Adaptor Proteins, Signal Transducing - metabolism | Ubiquitin-Protein Ligases - genetics | Transforming Growth Factor beta - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2013, Volume 8, Issue 7, pp. e70195 - e70195
Journal Article
British Journal of Cancer, ISSN 0007-0920, 08/2017, Volume 117, Issue 5, pp. 685 - 694
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2009, Volume 284, Issue 11, pp. 7149 - 7156
Journal Article