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hedgehog proteins - metabolism (415) 415
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hedgehog protein (93) 93
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Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 5, pp. 682 - 694
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2017, Volume 18, Issue 7, pp. 958 - 971
Journal Article
Nature Cell Biology, ISSN 1465-7392, 09/2017, Volume 19, Issue 10, pp. 1178 - 1188
Ciliopathies, including nephronophthisis (NPHP), Meckel syndrome (MKS) and Joubert syndrome (JBTS), can be caused by mutations affecting components of the... 
GENE | MEMBRANE | MECKEL-SYNDROME | PERICENTRIOLAR MATERIAL | NEPHRONOPHTHISIS | MUTATIONS | RPGRIP1L | PRIMARY CILIUM | HUMAN HOMOLOG | BASAL BODY PROTEIN | CELL BIOLOGY | Abnormalities, Multiple - metabolism | Abnormalities, Multiple - pathology | Retina - metabolism | Humans | Male | Smoothened Receptor - metabolism | Cerebellum - abnormalities | Patched-1 Receptor - genetics | Smoothened Receptor - genetics | Young Adult | Ciliopathies - genetics | Patched-1 Receptor - metabolism | Stochastic Processes | Kidney Diseases, Cystic - genetics | Adult | Female | Membrane Proteins - metabolism | Child | Eye Abnormalities - metabolism | Abnormalities, Multiple - genetics | Cell Line | Genetic Predisposition to Disease | Cilia - pathology | Signal Transduction | Membrane Proteins - genetics | Cerebellum - metabolism | Mice, Inbred C57BL | Eye Abnormalities - genetics | Cilia - metabolism | Cerebellum - pathology | Kidney Diseases, Cystic - pathology | Carrier Proteins - genetics | Kidney Diseases, Cystic - metabolism | Phenotype | Animals | Carrier Proteins - metabolism | Ciliopathies - metabolism | Eye Abnormalities - pathology | Image Processing, Computer-Assisted | Microscopy, Fluorescence - methods | Adaptor Proteins, Signal Transducing - genetics | Adolescent | Retina - abnormalities | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Retina - pathology | Ciliopathies - pathology | Brain | Meckel's syndrome | Nephronophthisis | Architecture | Congenital defects | Transition zone | Neurodevelopmental disorders | Membrane proteins | Proteins | Signaling | Protein composition | Microscopy | Animal behavior | Stochasticity | Disruption | Localization
Journal Article
Developmental Biology, ISSN 0012-1606, 07/2016, Volume 415, Issue 2, pp. 198 - 215
The Hedgehog signalling pathway plays a fundamental role in orchestrating normal craniofacial development in vertebrates. In particular, Sonic hedgehog (Shh)... 
Craniofacial development | Scube2 | Disease | Gpr161 | Holoprosencephaly | Sonic hedgehog | Dispatched | Smoothened | Boc | Gas1 | Patched1 | Patched2 | Lrp2/megalin | EvC1/2 | Cdon | CELL CARCINOMA SYNDROME | DEVELOPMENTAL BIOLOGY | EARLY EMBRYONIC-DEVELOPMENT | PRIMARY CILIA | VAN-CREVELD-SYNDROME | HUMAN SONIC HEDGEHOG | MOUSE PATCHED GENE | NEURAL CREST CELLS | PROTEIN-COUPLED RECEPTOR | WEYERS ACRODENTAL DYSOSTOSIS | IG SUPERFAMILY MEMBER | Cilia - physiology | Ectoderm - embryology | Ciliopathies - embryology | Holoprosencephaly - physiopathology | Face - abnormalities | Humans | Craniofacial Abnormalities - embryology | Endoderm - embryology | Hedgehog Proteins - physiology | Craniofacial Abnormalities - physiopathology | Ciliopathies - genetics | Maxillofacial Development - physiology | Gene Expression Regulation, Developmental | Membrane Proteins - physiology | Skull - abnormalities | Craniofacial Abnormalities - genetics | Maxillofacial Development - genetics | Disease Models, Animal | Neural Crest - cytology | Holoprosencephaly - genetics | Patched Receptors - physiology | Signal Transduction - genetics | Holoprosencephaly - embryology | Patched Receptors - genetics | Skull - embryology | Diencephalon - embryology | Animals | Ciliopathies - physiopathology | Neural Crest - embryology | Face - embryology | Cell Movement | Proteins | Cellular signal transduction | Analysis | Stem cells
Journal Article
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 09/2016, Volume 39, Issue 3, pp. 1129 - 1140
Background/Aims: Lipid accumulation, inflammatory responses and oxidative stress have been implicated in the pathology of alcoholic liver disease (ALD).... 
Original Paper | sonic hedgehog | Oxidative stress | inflammation | Baicalin | Alcoholic liver injury | Tumor Necrosis Factor-alpha - metabolism | Liver - pathology | Superoxide Dismutase - genetics | Rats, Wistar | Zinc Finger Protein GLI1 - metabolism | Apoptosis - drug effects | Humans | Tumor Necrosis Factor-alpha - genetics | Hedgehog Proteins - metabolism | Male | Hepatocytes - metabolism | Interleukin-1beta - genetics | Smoothened Receptor - metabolism | Hedgehog Proteins - agonists | Patched-1 Receptor - genetics | Smoothened Receptor - genetics | Liver Diseases, Alcoholic - drug therapy | Patched-1 Receptor - metabolism | Hepatocytes - cytology | Liver Diseases, Alcoholic - genetics | Hedgehog Proteins - genetics | Liver - drug effects | Interleukin-1beta - metabolism | Protective Agents - pharmacology | Flavonoids - pharmacology | Chemical and Drug Induced Liver Injury - pathology | Interleukin-6 - metabolism | Hepatocytes - drug effects | Scutellaria baicalensis - chemistry | Superoxide Dismutase - metabolism | Disease Models, Animal | Liver Diseases, Alcoholic - pathology | Liver Function Tests | Malondialdehyde - metabolism | Cell Line | Glutathione Peroxidase - metabolism | Ethanol | Interleukin-6 - genetics | Signal Transduction | Zinc Finger Protein GLI1 - genetics | Gene Expression Regulation | Rats | Chemical and Drug Induced Liver Injury - genetics | Glutathione Peroxidase - genetics | Liver Diseases, Alcoholic - metabolism | Animals | Chemical and Drug Induced Liver Injury - metabolism | Chemical and Drug Induced Liver Injury - drug therapy | Sonic hedgehog | Inflammation
Journal Article
Molecular Cell, ISSN 1097-2765, 04/2017, Volume 66, Issue 1, pp. 154 - 162.e10
Journal Article
Cell Reports, ISSN 2211-1247, 07/2017, Volume 20, Issue 2, pp. 384 - 396
Journal Article
Development (Cambridge), ISSN 0950-1991, 05/2017, Volume 144, Issue 10, pp. 1841 - 1850
Journal Article
Experimental Neurology, ISSN 0014-4886, 09/2016, Volume 283, Issue Pt A, pp. 235 - 245
Journal Article