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Neuron, ISSN 0896-6273, 2005, Volume 47, Issue 2, pp. 215 - 229
Accumulation of Na channels at the nodes of Ranvier is a prerequisite for saltatory conduction. In peripheral nerves, clustering of these channels along the... 
MYELINATED AXONS | PROTEIN | INITIAL SEGMENTS | PERIPHERAL NERVOUS-SYSTEM | BETA-IV-SPECTRIN | ADHESION MOLECULES | ANKYRIN-BINDING | IDENTIFICATION | NEUROSCIENCES | SODIUM-CHANNEL DISTRIBUTION | K+ CHANNELS | Cytoskeletal Proteins | Age Factors | Humans | Myelin-Associated Glycoprotein - metabolism | Cercopithecus aethiops | Sciatic Nerve - growth & development | Cell Adhesion Molecules - immunology | Phosphoproteins - metabolism | Ranvier's Nodes - metabolism | Ranvier's Nodes - ultrastructure | Cell Compartmentation | Sciatic Nerve - metabolism | Transfection - methods | Gene Expression Regulation, Developmental | Cloning, Molecular - methods | Sodium Channels - metabolism | Macromolecular Substances - immunology | Cell Adhesion Molecules, Neuronal - metabolism | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Spectrin - metabolism | Microscopy, Immunoelectron - methods | Protein Structure, Tertiary | Amino Acid Sequence | Blotting, Western - methods | Myelin Basic Protein - metabolism | Fluorescent Antibody Technique - methods | Cells, Cultured | Axons - metabolism | Rats | S100 Proteins - metabolism | Schwann Cells - metabolism | Cell Adhesion Molecules - metabolism | Claudins | Animals | Schwann Cells - ultrastructure | Ankyrins - metabolism | Blotting, Northern - methods | Neurofilament Proteins - metabolism | Macromolecular Substances - metabolism | Ganglia, Spinal - metabolism | Protein Binding - physiology | Receptors, Peptide - metabolism | Immunoglobulins | Proteins | Microscopy | Plasmids | Rodents | Ligands | Experiments | Binding sites | Index Medicus
Journal Article
Gut, ISSN 0017-5749, 05/2017, Volume 66, Issue 5, pp. 823 - 838
ObjectiveInterleukin (IL)-36R signalling plays a proinflammatory role in different organs including the skin, but the expression of IL-36R ligands and their... 
STEM-CELLS | IL-1-ALPHA | REPAIR | ANTAGONIST | ULCERATIVE-COLITIS | RECEPTOR | MICE | IL-1-BETA | LIGAND | GASTROENTEROLOGY & HEPATOLOGY | INFLAMMATORY BOWEL DISEASES | Dextran Sulfate | Intestinal Mucosa - metabolism | Cell Proliferation | Epithelial Cells - metabolism | Lipocalin-2 - biosynthesis | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Colitis - genetics | Humans | Receptors, Interleukin-1 - genetics | Cytoplasm - metabolism | Wound Healing | Inflammatory Bowel Diseases - metabolism | Receptors, Interleukin - metabolism | Cell Nucleus - metabolism | Colitis - chemically induced | Interleukin-6 - metabolism | Fibroblasts - metabolism | Calgranulin B - biosynthesis | Interleukin-1 - metabolism | Cytokines - metabolism | Myeloid Differentiation Factor 88 - genetics | Signal Transduction - genetics | Mice, Knockout | Receptors, Interleukin-1 - metabolism | Macrophages - metabolism | Animals | Colitis - metabolism | Ligands | Chemokines - metabolism | Mice | Myeloid Differentiation Factor 88 - metabolism | Fibroblasts | Intestines | Care and treatment | Cellular signal transduction | Research | Epithelial cells | Cell proliferation | Animal models | Mucosa | Genomes | CD14 antigen | Interleukin 6 | Signal transduction | Intestine | Rodents | Tumor necrosis factor-TNF | Colony-stimulating factor | Colon | Wound healing | Bacterial infections | Cytokines | Granulocyte-macrophage colony-stimulating factor | Lipocalin | Inflammation | Epithelium | Ribonucleic acid--RNA | Inflammatory bowel disease | Dextran | Sodium | Biopsy | MyD88 protein | Skin | Colitis | Chemokines | Cytoplasm | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Glia, ISSN 0894-1491, 10/2018, Volume 66, Issue 10, pp. 2233 - 2245
Astrocytes are a glial cell type, which is indispensable for brain energy metabolism. Within cells, the NADH/NAD + redox state is a crucial node in metabolism... 
NBCe1 | redox state | Peredox | astrocyte | NADH/NAD | OXIDATIVE-PHOSPHORYLATION | HIPPOCAMPAL SLICES | NAD(+)/NADH RATIO | NICOTINAMIDE-ADENINE DINUCLEOTIDE | GLUCOSE-UTILIZATION | EXTRACELLULAR K | NEUROSCIENCES | NADH/NAD(+) redox state | AEROBIC GLYCOLYSIS | BRAIN METABOLISM | ENERGY-METABOLISM | NAD(P)H FLUORESCENCE TRANSIENTS | L-Lactate Dehydrogenase - metabolism | Potassium - metabolism | Adenosine Triphosphate - administration & dosage | Oxidation-Reduction | Tissue Culture Techniques | Lactic Acid - metabolism | Mice, Inbred C57BL | Cells, Cultured | Cerebral Cortex - metabolism | Receptors, Purinergic - metabolism | Sodium-Bicarbonate Symporters - metabolism | Extracellular Space - metabolism | Glutamic Acid - administration & dosage | Animals | Adenosine Triphosphate - metabolism | Intracellular Space - metabolism | Cytosol - metabolism | Glutamic Acid - metabolism | Neurons - metabolism | NAD - metabolism | Astrocytes - metabolism | Neurons | Brain | Energy metabolism | Phosphorylation | Purine receptors | Brain slice preparation | Bicarbonates | Neuronal-glial interactions | Bicarbonate | Heterogeneity | Genetic code | Mitochondria | Receptors | NADH | Coding | Inhibition | Redox properties | Astrocytes | Cortex | Lactate dehydrogenase | Calibration | Metabolism | L-Lactate dehydrogenase | NAD | Neurotransmitters | Oxidative phosphorylation | Sodium | Nicotinamide adenine dinucleotide | Energy demand | Lactic acid | ATP | Potassium | Index Medicus
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 10/2017, Volume 32, Issue 10, pp. 2049 - 2061
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 05/2015, Volume 290, Issue 22, pp. 13875 - 13887
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1763 - 1774
Background & Aims The NACHT, LRR, and pyrin domain–containing protein 3 (NLRP3) inflammasome induces inflammation in response to organ injury, but little is... 
Gastroenterology and Hepatology | Innate Immune Response | Immune Regulation | Pancreas | Mouse Model | ACTIVATION | NLRP3 INFLAMMASOME | GPR81 | AGONISTS | GENE | TLR9 | MICE | HEPATOTOXICITY | GASTROENTEROLOGY & HEPATOLOGY | EXPRESSION | SEVERITY | Liver - pathology | Inflammasomes - metabolism | Receptors, G-Protein-Coupled - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Humans | Male | NF-kappa B - metabolism | Monocytes - immunology | Lipopolysaccharides | Liver - immunology | Liver - drug effects | RNA Interference | Interleukin-1beta - metabolism | Toll-Like Receptors - drug effects | Anti-Inflammatory Agents - administration & dosage | Toll-Like Receptors - metabolism | Cytoprotection | Disease Models, Animal | Galactosamine | Chemical and Drug Induced Liver Injury - prevention & control | Anti-Inflammatory Agents - pharmacology | Down-Regulation | Liver - metabolism | Injections, Intraperitoneal | Pancreas - pathology | Pancreas - metabolism | Pancreas - immunology | Toll-Like Receptor 4 - metabolism | Chemical and Drug Induced Liver Injury - immunology | Monocytes - drug effects | Macrophages - metabolism | Signal Transduction - drug effects | Chemical and Drug Induced Liver Injury - metabolism | Sodium Lactate - pharmacology | beta-Arrestins | Mice | Receptors, G-Protein-Coupled - genetics | RNA, Small Interfering - metabolism | Monocytes - metabolism | Pancreatitis - prevention & control | Arrestins - metabolism | Dose-Response Relationship, Drug | Pancreatitis - genetics | Transfection | Inflammasomes - drug effects | Sodium Lactate - administration & dosage | Pancreatitis - immunology | Chemical and Drug Induced Liver Injury - pathology | Chemical and Drug Induced Liver Injury - etiology | Macrophages - immunology | Cell Line | Immunity, Innate - drug effects | Toll-Like Receptor 4 - drug effects | Mice, Inbred C57BL | Pancreas - drug effects | Chemical and Drug Induced Liver Injury - genetics | Pancreatitis - chemically induced | Animals | Carrier Proteins - metabolism | beta-Arrestin 2 | Inflammasomes - immunology | Macrophages - drug effects | Pancreatitis - pathology | Pancreatitis - metabolism | Ceruletide | Lactates | Gastrointestinal diseases | Inflammation | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 07/2013, Volume 54, Issue 3-4, pp. 482 - 492
► Oral treatment with α,β-amyrin ameliorate disease activity in DSS-induced colitis. ► α,β-Amyrin treatment decrease leukocyte influx to the colon. ► The... 
Inflammatory bowel disease | α,β-Amyrin | Dextran sodium sulfate | Inflammatory cytokines | Cannabinoid system | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | alpha,beta-amyrin | MECHANISMS | BETA-AMYRIN | ADHESION MOLECULES | IMMUNOLOGY | PROTIUM-HEPTAPHYLLUM | ALPHA-AMYRIN | INFLAMMATORY-BOWEL-DISEASE | MOUSE MODEL | RECEPTORS | EXPRESSION | P-Selectin - metabolism | Colitis - genetics | Tumor Necrosis Factor-alpha - genetics | Colon - drug effects | Body Weight - drug effects | Ki-67 Antigen - metabolism | Male | Interleukin-1beta - genetics | Antigens, CD - genetics | Body Weight - genetics | Antigens, CD - metabolism | Lectins, C-Type - metabolism | Interleukin-1beta - metabolism | Cannabinoids - genetics | Colitis - drug therapy | Cannabinoids - metabolism | Administration, Oral | CD18 Antigens - genetics | Membrane Proteins - genetics | Asialoglycoproteins - metabolism | P-Selectin - genetics | Cell Adhesion Molecules - metabolism | Chemokines - genetics | Colon - metabolism | CD18 Antigens - metabolism | Intercellular Adhesion Molecule-1 - metabolism | Receptor, Cannabinoid, CB1 - genetics | Ki-67 Antigen - genetics | Intercellular Adhesion Molecule-1 - genetics | Colitis - metabolism | Chemokines - metabolism | Mice | Vascular Cell Adhesion Molecule-1 - metabolism | Tumor Necrosis Factor-alpha - metabolism | Dextran Sulfate | Cell Adhesion Molecules - genetics | Oleanolic Acid - analogs & derivatives | Oleanolic Acid - pharmacology | Lectins, C-Type - genetics | Receptor, Cannabinoid, CB2 - genetics | Asialoglycoproteins - genetics | Colitis - chemically induced | Vascular Cell Adhesion Molecule-1 - genetics | Membrane Proteins - metabolism | Interleukin-4 - genetics | Amidohydrolases - metabolism | Amidohydrolases - genetics | Interleukin-4 - metabolism | RNA, Messenger - genetics | Up-Regulation - genetics | Antigens, Differentiation, Myelomonocytic - genetics | Up-Regulation - drug effects | Receptor, Cannabinoid, CB1 - metabolism | Receptor, Cannabinoid, CB2 - metabolism | Animals | Antigens, Differentiation, Myelomonocytic - metabolism | Peroxidase - genetics | Peroxidase - metabolism | Index Medicus
Journal Article