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1. Full Text Hemodynamic effects of sodium bicarbonate administration
by Katheria, A.C and Brown, M.K and Hassan, K and Poeltler, D.M and Patel, D.A and Brown, V.K and Sauberan, J.B
Journal of Perinatology, ISSN 0743-8346, 02/2017, Volume 37, Issue 5, pp. 518 - 520
OBJECTIVE: To describe the hemodynamic changes that occur with sodium bicarbonate (NaHCO3) administration in premature neonates. STUDY DESIGN: This... 
CORD | NEONATAL RESUSCITATION | BIRTH-WEIGHT INFANTS | TISSUE OXYGENATION | THERAPY | RISK | PEDIATRICS | PRETERM INFANTS | LACTIC-ACIDOSIS | RANDOMIZED CONTROLLED-TRIAL | TERM | OBSTETRICS & GYNECOLOGY | Cerebrovascular Circulation - drug effects | Cardiac Output - drug effects | Humans | Blood Gas Analysis | Male | Sodium Bicarbonate - administration & dosage | California | Gestational Age | Heart Rate - drug effects | Infant, Extremely Premature - physiology | Female | Blood Pressure - drug effects | Retrospective Studies | Infant, Newborn | Sodium bicarbonate | Dosage and administration | Hemodynamics | Infants (Premature) | Health aspects | Analysis
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2. Full Text Effect of Sodium Bicarbonate Administration on Mortality in Patients with Lactic Acidosis: A Retrospective Analysis
by Kim, Hyun Jeong and Son, Young Ki and An, Won Suk
PLoS ONE, ISSN 1932-6203, 06/2013, Volume 8, Issue 6, p. e65283
Background: Lactic acidosis is a common cause of high anion gap metabolic acidosis. Sodium bicarbonate may be considered for an arterial pH <7.15 but... 
ARTERIAL | THERAPY | MULTIDISCIPLINARY SCIENCES | LACTATE | DISEASE | FAILURE | HEMODYNAMICS | BLOOD | Multivariate Analysis | Hospital Mortality | Humans | Middle Aged | Proportional Hazards Models | Logistic Models | Male | Sodium Bicarbonate - administration & dosage | Treatment Outcome | Acidosis, Lactic - drug therapy | Sepsis - mortality | Sepsis - metabolism | Female | Acidosis, Lactic - etiology | Acidosis, Lactic - mortality | Aged | Retrospective Studies | Shock | Medical research | Patient outcomes | Mortality | Albumin | Medicine, Experimental | Sodium bicarbonate | Lactic acid | Carbonates | Lactic acidosis | Intensive care | Laboratories | Liver | Critical care | Infections | pH effects | Blood | Bicarbonate | Heart diseases | Metabolic acidosis | Ventilators | Edema | Internal medicine | Regression analysis | Metabolism | Catecholamine | Patients | Survival | Medicine | Hospitals | Acids | Sodium | Sepsis | Acidosis | pH
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3. Full Text Loss of Acid Sensing Ion Channel-1a and Bicarbonate Administration Attenuate the Severity of Traumatic Brain Injury
by Yin, Terry and Lindley, Timothy E and Albert, Gregory W and Ahmed, Raheel and Schmeiser, Peter B and Grady, M. Sean and Howard, Matthew A and Welsh, Michael J
PLoS ONE, ISSN 1932-6203, 08/2013, Volume 8, Issue 8, p. e72379
Traumatic brain injury (TBI) is a common cause of morbidity and mortality in people of all ages. Following the acute mechanical insult, TBI evolves over the... 
OXIDATIVE STRESS | NEURONAL DEGENERATION | CLINICAL-TRIAL | MULTIDISCIPLINARY SCIENCES | SEVERE HEAD-INJURY | FLUID PERCUSSION | MYOCARDIAL-ISCHEMIA | LACTIC-ACIDOSIS | HIPPOCAMPAL-NEURONS | ACTIVATED CURRENTS | ASICS | Severity of Illness Index | Fear | Bicarbonates - administration & dosage | Bicarbonates - therapeutic use | Brain Injuries - drug therapy | Humans | Memory | Acid Sensing Ion Channels - genetics | Brain Injuries - genetics | Brain Injuries - psychology | Brain | Carbonates | Analysis | Injuries | Sodium channels | Neurosciences | Traumatic brain injury | Internal medicine | Clinical trials | Percussion | Acidity | Neurosurgery | Kinases | Morbidity | Medicine | Studies | Bicarbonate | Hypotheses | Head injuries | Acids | Ischemia | Neurodegeneration | Rodents | Mice | Ion channels | Acidosis
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4. Full Text Effect of perioperative sodium bicarbonate administration on renal function following cardiac surgery for infective endocarditis: A randomized, placebo-controlled trial
by Cho, Jin Sun and Soh, Sarah and Shim, Jae-Kwang and Kang, Sanghwa and Choi, Haegi and Kwak, Young-Lan
Critical Care, ISSN 1364-8535, 01/2017, Volume 21, Issue 1, p. 3
Background: Patients with infective endocarditis (IE) have an elevated risk of renal dysfunction because of extensive systemic inflammation and use of... 
Infective endocarditis | Sodium bicarbonate | Renal function | Cardiac surgery | ACUTE KIDNEY INJURY | MEDIUM-INDUCED NEPHROPATHY | SCORE | PREVENTION | RATS | INFUSION | IMPACT | DOUBLE-BLIND | CRITICALLY-ILL PATIENTS | RESUSCITATION | CRITICAL CARE MEDICINE | Sodium Bicarbonate - therapeutic use | Kidney - drug effects | Prospective Studies | Acute Kidney Injury - drug therapy | Humans | Middle Aged | Postoperative Complications - prevention & control | Male | Sodium Bicarbonate - administration & dosage | Sodium Chloride - administration & dosage | Kidney Function Tests - statistics & numerical data | Acute Kidney Injury - prevention & control | Aged, 80 and over | Adult | Cardiac Surgical Procedures - statistics & numerical data | Female | Aged | Cardiac Surgical Procedures - methods | Endocarditis - drug therapy | Placebos - administration & dosage | Republic of Korea | Endocarditis - surgery
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5. Full Text Sodium Bicarbonate Administration and Outcome in Preterm Infants
by Berg, Carly S and Barnette, Alan R., MD and Myers, Brian J., BS and Shimony, Maya K and Barton, Anthony W and Inder, Terrie E., MD, MBChB
Journal of Pediatrics, The, ISSN 0022-3476, 2010, Volume 157, Issue 4, pp. 684 - 687
The short-term outcomes of sodium bicarbonate therapy in preterm infants were investigated by retrospective analysis of 165 of 984 infants who received sodium... 
Pediatrics | CONTROLLED-TRIAL | THERAPY | HEMORRHAGE | PERFORMANCE | ACIDOSIS | RISK | PEDIATRICS | INFUSION | Severity of Illness Index | Acidosis - drug therapy | Humans | Hydrogen-Ion Concentration - drug effects | Infant, Premature | Sodium Bicarbonate - pharmacology | Sodium Bicarbonate - administration & dosage | Infusions, Intravenous | Acidosis - metabolism | Chronic Disease | Infant, Newborn | Sodium bicarbonate | Carbonates | Infants (Premature) | Analysis
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6. Full Text Sodium bicarbonate administration during ongoing resuscitation is associated with increased return of spontaneous circulation
by Kim, Joonghee, MD, MS and Kim, Kyuseok, MD, PhD and Park, Jongdae, MD and Jo, You Hwan, MD, PhD and Lee, Jae Hyuk, MD, PhD and Hwang, Ji Eun, MD and Ha, Chulmin, MD and Ko, Young-sang, MD and Jung, Euigi, MD
American Journal of Emergency Medicine, ISSN 0735-6757, 2015, Volume 34, Issue 2, pp. 225 - 229
Abstract Purpose Sodium bicarbonate is frequently used for patients unresponsive to cardiopulmonary resuscitation (CPR). Its use may be associated with longer... 
Emergency | CARBICARB | ARTERIAL | LIFE-SUPPORT | EMERGENCY MEDICINE | HYPOXIC LACTIC-ACIDOSIS | GUIDELINES | IMPROVES | HOSPITAL CARDIAC-ARREST | AMERICAN-HEART-ASSOCIATION | CARDIOPULMONARY-RESUSCITATION | INTRACELLULAR ACIDOSIS | Sodium Bicarbonate - therapeutic use | Cardiopulmonary Resuscitation - methods | Emergency Service, Hospital | Prospective Studies | Humans | Middle Aged | Male | Treatment Outcome | Case-Control Studies | Out-of-Hospital Cardiac Arrest - drug therapy | Female | Registries | Aged | Sodium bicarbonate | Carbonates | Variables | Chemical industry | Heart attacks | Sodium | Medical prognosis | Metabolism | Cardiopulmonary resuscitation--CPR | Logistics
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7. Full Text The effect of bicarbonate administration via continuous venovenous hemofiltration on acid-base parameters in ventilated patients
by Allegretti, Andrew S and Flythe, Jennifer E and Benda, Vinod and Robinson, Emily S and Charytan, David M
BioMed Research International, ISSN 2314-6133, 01/2015, Volume 2015, pp. 901590 - 8
Background. Acute kidney injury (AKI) and metabolic acidosis are common in the intensive care unit. The effect of bicarbonate administration on acid-base... 
RENAL-REPLACEMENT THERAPY | MEDICINE, RESEARCH & EXPERIMENTAL | SODIUM-BICARBONATE | CARDIAC-ARREST | METABOLIC-ACIDOSIS | INTENSIVE-CARE-UNIT | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | MIXED ACIDEMIA | INTRACELLULAR PH | LACTIC-ACIDOSIS | CRITICALLY-ILL PATIENTS | FAILURE | Prospective Studies | Bicarbonates - therapeutic use | Humans | Middle Aged | Bicarbonates - pharmacology | Male | Carbon Dioxide - blood | Respiration, Artificial | Acid-Base Equilibrium - drug effects | Arterial Pressure | Bicarbonates - administration & dosage | Adult | Female | Aged | Hemofiltration - methods | Hydrogen-Ion Concentration | Bicarbonates | Filtration | Health aspects | Artificial respiration | Blood | Ventilators | Nephrology | Laboratories | Mortality | Fluid | Carbon dioxide | Metabolism | Studies | Medicine | Ostomy | Acids | Sodium | Womens health | Electrolytes
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8. Full Text Sodium Bicarbonate vs Sodium Chloride for the Prevention of Contrast Medium–Induced Nephropathy in Patients Undergoing Coronary Angiography: A Randomized Trial
by Brar, Somjot S and Shen, Albert Yuh-Jer and Jorgensen, Michael B and Kotlewski, Adam and Aharonian, Vicken J and Desai, Natasha and Ree, Michael and Shah, Ahmed Ijaz and Burchette, Raoul J
JAMA, ISSN 0098-7484, 09/2008, Volume 300, Issue 9, pp. 1038 - 1046
CONTEXT Sodium bicarbonate has been suggested as a possible strategy for prevention of contrast medium–induced nephropathy, a common cause of renal failure... 
DIABETES-MELLITUS | REDUCTIONS | MORTALITY | MEDICINE, GENERAL & INTERNAL | FENOLDOPAM MESYLATE | INSUFFICIENCY | ACUTE-RENAL-FAILURE | CHRONIC KIDNEY-DISEASE | INTERVENTION | PREDICTION | NEPHROTOXICITY | Single-Blind Method | Glomerular Filtration Rate | Humans | Risk Factors | Male | Sodium Bicarbonate - administration & dosage | Sodium Chloride - administration & dosage | Renal Insufficiency - prevention & control | Renal Insufficiency - epidemiology | Iohexol - adverse effects | Renal Insufficiency, Chronic - epidemiology | Coronary Angiography | Contrast Media - adverse effects | Renal Insufficiency - chemically induced | Diabetes Mellitus - epidemiology | Iopamidol - adverse effects | Female | Aged | Iohexol - analogs & derivatives | Prevention | Sodium bicarbonate | Usage | Nephrotic syndrome | Health aspects | Index Medicus | Abridged Index Medicus
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9. Full Text Bicarbonate supplementation slows progression of CKD and improves nutritional status
by De Brito-Ashurst, Ione and Varagunam, Mira and Raftery, Martin J and Yaqoob, Muhammad M
Journal of the American Society of Nephrology, ISSN 1046-6673, 09/2009, Volume 20, Issue 9, pp. 2075 - 2084
Bicarbonate supplementation preserves renal function in experimental chronic kidney disease (CKD), but whether the same benefit occurs in humans is unknown.... 
SERUM BICARBONATE | MUSCLE PROTEOLYSIS | BODY PROTEIN-DEGRADATION | DIALYSIS PATIENTS | CHRONIC METABOLIC-ACIDOSIS | DISEASE | HEMODIALYSIS-PATIENTS | UROLOGY & NEPHROLOGY | BRANCHED-CHAIN | AMMONIUM-CHLORIDE | CHRONIC-RENAL-FAILURE | Dietary Proteins - administration & dosage | Sodium Bicarbonate - adverse effects | Acidosis - drug therapy | Administration, Oral | Humans | Kidney Failure, Chronic - drug therapy | Middle Aged | Kaplan-Meier Estimate | Male | Sodium Bicarbonate - administration & dosage | Treatment Outcome | Acidosis - metabolism | Blood Proteins - metabolism | Disease Progression | Kidney Failure, Chronic - metabolism | Sodium Bicarbonate - blood | Acidosis - complications | Kidney Failure, Chronic - complications | Creatinine - blood | Female | Nutritional Status | Serum Albumin - metabolism | Index Medicus | Clinical Research
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10. Full Text The Reno-Protective Effect of Hydration With Sodium Bicarbonate Plus N-Acetylcysteine in Patients Undergoing Emergency Percutaneous Coronary Intervention. The RENO Study
by Recio-Mayoral, Alejandro and Chaparro, Marinela and Prado, Belén and Cózar, Rocío and Méndez, Irene and Banerjee, Debasish and Kaski, Juan C and Cubero, José and Cruz, Jose M
Journal of the American College of Cardiology, ISSN 0735-1097, 03/2007, Volume 49, Issue 12, pp. 1283 - 1288
Objectives: This study was designed to determine the effectiveness of a protocol for rapid intravenous hydration to prevent contrast-induced nephropathy (CIN)... 
PATHOGENESIS | ANGIOGRAPHY | CARDIAC & CARDIOVASCULAR SYSTEMS | AGENT-ASSOCIATED NEPHROTOXICITY | ACUTE MYOCARDIAL-INFARCTION | PREVENTION | CONTRAST-INDUCED NEPHROPATHY | RANDOMIZED CONTROLLED-TRIAL | DYSFUNCTION | CRITICALLY-ILL PATIENTS | PRIMARY ANGIOPLASTY | Single-Blind Method | Prospective Studies | Angioplasty, Balloon, Coronary - methods | Humans | Middle Aged | Coronary Disease - physiopathology | Male | Sodium Bicarbonate - administration & dosage | Fluid Therapy - methods | Coronary Disease - therapy | Female | Aged | Emergency Medical Services - methods | Acetylcysteine - administration & dosage | Hypertension | Contrast agents | Enzymes | Heart attacks | Medical imaging | Free radicals | Sodium | Ischemia | Hydration | Mortality | Intubation | Acute coronary syndromes
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11. Full Text Effect of β-alanine plus sodium bicarbonate on high-intensity cycling capacity
by Sale, Craig and Saunders, Bryan and Hudson, Sean and Wise, John A and Harris, Roger C and Sunderland, Caroline D
Medicine and Science in Sports and Exercise, ISSN 0195-9131, 10/2011, Volume 43, Issue 10, pp. 1972 - 1978
SALE, C., B. SAUNDERS, S. HUDSON, J. A. WISE, R. C. HARRIS, and C. D. SUNDERLAND. Effect of beta-Alanine Plus Sodium Bicarbonate on High-Intensity Cycling... 
buffering | β-alanine | carnosine | high-intensity cycling capacity | sodium bicarbonate | BUFFERING | SPORT SCIENCES | beta-ALANINE | ACID-BASE-BALANCE | SARCOPLASMIC-RETICULUM | CARNOSINE | EXERCISE | SUPPLEMENTATION | MUSCLE BUFFERING CAPACITY | SKELETAL-MUSCLE | REPEATED-SPRINT ABILITY | SODIUM BICARBONATE | LACTATE | HIGH-INTENSITY CYCLING CAPACITY | Lactic Acid - blood | Humans | beta-Alanine - administration & dosage | Male | Sodium Bicarbonate - administration & dosage | Bicycling - psychology | Cross-Over Studies | Sodium Bicarbonate - blood | Young Adult | Exercise Test | Hydrogen-Ion Concentration - drug effects | Adult | Polysaccharides - administration & dosage | Dietary Supplements | Physical Endurance - drug effects
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12. Full Text Daily oral sodium bicarbonate preserves glomerular filtration rate by slowing its decline in early hypertensive nephropathy
by Mahajan, Ashutosh and Simoni, Jan and Sheather, Simon J and Broglio, Kristine R and Rajab, M.H and Wesson, Donald E
Kidney International, ISSN 0085-2538, 08/2010, Volume 78, Issue 3, pp. 303 - 309
In most patients with hypertensive nephropathy and low glomerular filtration rate (GFR), the kidney function progressively declines despite the adequate... 
albuminuria | chronic metabolic acidosis | chronic kidney disease | hypertension | acidosis | SYSTEM | DISTAL TUBULE ACIDIFICATION | INJURY | BLOOD-PRESSURE | CIGARETTE-SMOKING | METABOLIC-ACIDOSIS | CYSTATIN-C | UROLOGY & NEPHROLOGY | ENDOTHELIN | CHRONIC KIDNEY-DISEASE | PROGRESSION | Kidney Diseases - physiopathology | Antihypertensive Agents - pharmacology | Prospective Studies | Cystatin C - blood | Humans | Middle Aged | Hypertension - drug therapy | Male | Sodium Bicarbonate - administration & dosage | Albuminuria - physiopathology | Glomerular Filtration Rate - drug effects | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Adult | Female | Angiotensin-Converting Enzyme Inhibitors - pharmacology | Blood Pressure - drug effects | Drug Therapy, Combination | Kidney - physiopathology | Kidney - drug effects | Double-Blind Method | Administration, Oral | Sodium Bicarbonate - pharmacology | Kidney Diseases - drug therapy | Antihypertensive Agents - therapeutic use | Hypertension - physiopathology | Albuminuria - drug therapy | Hypertension - complications | Kidney Diseases - etiology | Longitudinal Studies
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13. Full Text Systematic Review: Sodium Bicarbonate Treatment Regimens for the Prevention of Contrast-Induced Nephropathy
by Zoungas, S and Ninomiya, T and Huxley, R and Cass, A and Jardine, M and Gallagher, M and Patel, A and Vasheghani-Farahani, A and Sadigh, G and Perkovic, V
ANNALS OF INTERNAL MEDICINE, ISSN 0003-4819, 11/2009, Volume 151, Issue 9, pp. 631 - W207
Background: Intravenous sodium bicarbonate has been proposed to reduce the risk for contrast-induced nephropathy (CIN). Purpose: To determine the effect of... 
MEDICINE, GENERAL & INTERNAL | PERCUTANEOUS CORONARY INTERVENTION | RADIOCONTRAST-INDUCED NEPHROPATHY | METAANALYSIS | INSUFFICIENCY | CONSENSUS | ACUTE-RENAL-FAILURE | N-ACETYLCYSTEINE | RANDOMIZED CLINICAL-TRIALS | HYDRATION | CHLORIDE | Injections, Intravenous | Sodium Bicarbonate - adverse effects | Kidney Diseases - prevention & control | Humans | Mortality | Risk | Sodium Bicarbonate - administration & dosage | Heart Failure - prevention & control | Contrast Media - adverse effects | Kidney Diseases - chemically induced | Kidney Diseases - therapy | Acetylcysteine - administration & dosage | Heart Failure - chemically induced | Renal Dialysis | Prevention | Sodium bicarbonate | Nephrotic syndrome | Dosage and administration | Research | Index Medicus | Abridged Index Medicus
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14. Full Text A Comparison of Treating Metabolic Acidosis in CKD Stage 4 Hypertensive Kidney Disease with Fruits and Vegetables or Sodium Bicarbonate
by Nimrit Goraya and Jan Simoni and Chan-Hee Jo and Donald E. Wesson
Clinical Journal of the American Society of Nephrology, ISSN 1555-9041, 03/2013, Volume 8, Issue 3, pp. 371 - 381
Background and objectives Current guidelines recommend Na+-based alkali for CKD with metabolic acidosis and plasma total CO2 (PTCO2) < 22 mM. Because diets in... 
GLOMERULAR-FILTRATION-RATE | BODY-WEIGHT | GFR | DIET | CYSTATIN-C | UROLOGY & NEPHROLOGY | ENDOTHELIN | POTASSIUM | BLOOD-PRESSURE | PROGRESSION | DECLINE | Sodium Bicarbonate - therapeutic use | Biomarkers - urine | Sodium Bicarbonate - adverse effects | Vegetables | Renal Insufficiency, Chronic - etiology | Diet - adverse effects | Humans | Middle Aged | Hypertension - drug therapy | Male | Sodium Bicarbonate - administration & dosage | Renal Insufficiency, Chronic - drug therapy | Glomerular Filtration Rate - drug effects | Angiotensin-Converting Enzyme Inhibitors - therapeutic use | Time Factors | Female | Renal Insufficiency, Chronic - diagnosis | Renal Insufficiency, Chronic - diet therapy | Kidney - physiopathology | Kidney - drug effects | Acidosis - etiology | Fruit | Acidosis - drug therapy | Administration, Oral | Acidosis - diet therapy | Treatment Outcome | Biomarkers - blood | Antihypertensive Agents - therapeutic use | Acid-Base Equilibrium - drug effects | Texas | Acidosis - diagnosis | Hypertension - complications | Potassium - blood | Original
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