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Lancet Neurology, The, ISSN 1474-4422, 2017, Volume 16, Issue 4, pp. 255 - 256
  [...]more specific drugs with fewer adverse effects are needed to treat trigeminal neuralgia. Despite these limitations, the study is interesting and a... 
Neurology | CLINICAL NEUROLOGY | Sodium | Pain
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 05/2007, Volume 50, Issue 11, pp. 2583 - 2588
PERIPHERAL-NERVE INJURY | SPINAL SENSORY NEURONS | NEUROPATHIC PAIN | CHEMISTRY, MEDICINAL | SUBUNIT MESSENGER-RNAS | ORAL MEXILETINE | POSTHERPETIC NEURALGIA | CLOSED-STATE INACTIVATION | UP-REGULATION | INTRAVENOUS LIDOCAINE INFUSION | GATED NA+ CHANNELS | Analgesics - pharmacology | Semicarbazones - therapeutic use | Anti-Arrhythmia Agents - pharmacology | Humans | Semicarbazones - chemistry | Cyclopentanes - chemistry | Peripheral Nervous System Diseases - physiopathology | Sodium Channels - physiology | Pain - metabolism | Anticonvulsants - pharmacology | Anesthetics, Local - pharmacology | Pyrimidines - chemistry | Benzyl Compounds - chemistry | Pain - drug therapy | Benzyl Compounds - therapeutic use | Sodium Channel Blockers - therapeutic use | Anesthetics, Local - therapeutic use | Analgesics - therapeutic use | Anesthetics, Local - chemistry | Anticonvulsants - therapeutic use | Sodium Channel Blockers - pharmacology | Sodium Channels - drug effects | Anti-Arrhythmia Agents - chemistry | Anti-Arrhythmia Agents - therapeutic use | Cyclopentanes - pharmacology | Pyrimidines - pharmacology | Peripheral Nervous System Diseases - metabolism | Animals | Benzyl Compounds - pharmacology | Analgesics - chemistry | Pain - physiopathology | Pyrimidines - therapeutic use | Anticonvulsants - chemistry | Cyclopentanes - therapeutic use | Semicarbazones - pharmacology | Sodium Channel Blockers - chemistry | Ion Channel Gating | Peripheral Nervous System Diseases - drug therapy | Sodium Channels - classification
Journal Article
Journal Article
Journal Article
Bioorganic & Medicinal Chemistry Letters, ISSN 0960-894X, 01/2015, Volume 25, Issue 1, pp. 43 - 47
Journal Article
Journal of the American College of Cardiology, ISSN 0735-1097, 2016, Volume 68, Issue 17, pp. 1881 - 1894
Abstract Background Antiarrhythmic drugs are widely used to treat patients with atrial fibrillation (AF), but the mechanisms conveying their variable... 
Cardiovascular | Internal Medicine | drug targets | antiarrhythmic drugs | atrial fibrillation | electrophysiology | personalized medicine | rhythm control | POST-REPOLARIZATION REFRACTORINESS | FIBRILLATION | POSTREPOLARIZATION REFRACTORINESS | CARDIAC & CARDIOVASCULAR SYSTEMS | MECHANISMS | EXPERIMENTAL-MODEL | PLEXUS ABLATION | RANOLAZINE | TASK-1 | DRONEDARONE | K+ CHANNEL | Transcription Factors - physiology | Atrial Fibrillation - drug therapy | Anti-Arrhythmia Agents - pharmacology | Humans | Middle Aged | Gene Expression Regulation | Male | Transcription Factors - genetics | Atrial Fibrillation - physiopathology | Membrane Potentials - physiology | Homeodomain Proteins - genetics | Animals | Voltage-Gated Sodium Channel Blockers - therapeutic use | Adult | Female | Aged | Mice | Electrophysiological Phenomena | Heart Atria - physiopathology | Homeodomain Proteins - physiology | Flecainide - therapeutic use | Heart | Medical colleges | Hospitals | Atrial fibrillation | Anti-arrhythmia drugs | Cardiology | Gene expression | Pharmaceutical industry | Electric properties | Cardiac arrhythmia | Transcription factors | Sodium | Velocity | Rodents | Deoxyribonucleic acid--DNA | LAA, left atrial appendage | PITX2, paired like homeodomain-2 | APD, action potential duration | ERP, effective refractory period | LA, left atrium | TASK-2, TWIK-related acid-sensitive K+ channel | RMP, resting membrane potential | HEK, human embryonic kidney | Na, sodium | SNP, single nucleotide polymorphism | PRR, post-repolarization refractoriness | mRNA, messenger ribonucleic acid | Original Investigation | AAD, antiarrhythmic drug
Journal Article
European Journal of Neuroscience, ISSN 0953-816X, 09/2019, Volume 50, Issue 5, pp. 2847 - 2859
Experimental and clinical studies suggest that the low‐affinity N‐methyl‐d‐aspartate (NMDA) receptor open‐channel blockers Mg2+ and memantine are effective in... 
microiontophoresis | naratriptan | migraine | headache | glutamate | Headache | Pain perception | Intravenous administration | Glutamic acid receptors (ionotropic) | Exploration | N-Methyl-D-aspartic acid receptors | Ions | Memantine | Sodium | Sensory neurons | Dura mater | Magnesium | Neurotransmission
Journal Article
Neurotherapeutics, ISSN 1933-7213, 1/2016, Volume 13, Issue 1, pp. 190 - 191
Journal Article
Journal of Neuroscience Research, ISSN 0360-4012, 06/2011, Volume 89, Issue 6, pp. 791 - 801
The activation of a delayed secondary cascade of unsatisfactory cellular and molecular responses after a primary mechanical insult to the spinal cord causes... 
spinal cord injury | sodium | potassium | calcium | Calcium | Sodium | Spinal cord injury |