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Journal Article
PloS one, ISSN 1932-6203, 07/2017, Volume 12, Issue 7, pp. e0180154 - e0180154
Ion channels regulate a variety of physiological processes and represent an important class of drug target... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cricetulus | High-Throughput Screening Assays - instrumentation | NAV1.3 Voltage-Gated Sodium Channel - genetics | NAV1.1 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - metabolism | NAV1.1 Voltage-Gated Sodium Channel - metabolism | NAV1.4 Voltage-Gated Sodium Channel - metabolism | Kv1.3 Potassium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - metabolism | NAV1.3 Voltage-Gated Sodium Channel - metabolism | Patch-Clamp Techniques - methods | Kv1.3 Potassium Channel - deficiency | T-Lymphocytes - metabolism | T-Lymphocytes - drug effects | Sodium Channels - metabolism | NAV1.7 Voltage-Gated Sodium Channel - genetics | NAV1.5 Voltage-Gated Sodium Channel - genetics | Drug Evaluation, Preclinical | Transgenes | Potassium Channel Blockers - pharmacology | CHO Cells | High-Throughput Screening Assays - methods | Gene Expression | NAV1.4 Voltage-Gated Sodium Channel - genetics | NAV1.2 Voltage-Gated Sodium Channel - genetics | Rats | Sodium Channel Blockers - pharmacology | Membrane Potentials - physiology | Animals | T-Lymphocytes - cytology | NAV1.6 Voltage-Gated Sodium Channel - metabolism | NAV1.7 Voltage-Gated Sodium Channel - metabolism | NAV1.6 Voltage-Gated Sodium Channel - genetics | Sodium Channels - genetics | Primary Cell Culture | Patch-Clamp Techniques - instrumentation | Ion channels | Information management | Drug discovery | T cells | Modules | Electrophysiology | Patching | Lymphocytes T | Boundaries | Assaying | Channels | Step voltage | Immunology | Pain | Lymphocytes | Sodium channels (voltage-gated) | Physiology | Potassium channels (voltage-gated) | Gold | Platforms | Data points | Automation | Cloning | Pharmacology | Sodium | Antigen-presenting cells | Ligands | Mutation | Recording | Potassium | Index Medicus
Journal Article
PloS one, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, pp. e0133037 - e0133037
.... Genetic variation is identified and associated with 30-35% of cases of Brugada Syndrome, with nearly 20-25... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Brugada Syndrome - genetics | Brugada Syndrome - diagnosis | Genetic Testing | Cytoskeletal Proteins - genetics | Humans | Middle Aged | Male | Calsequestrin - genetics | Death, Sudden, Cardiac | Genetic Variation | A Kinase Anchor Proteins - genetics | gamma Catenin | Desmoplakins - genetics | Clinical Decision-Making | Adult | Female | Retrospective Studies | NAV1.5 Voltage-Gated Sodium Channel - genetics | Arrhythmias, Cardiac - genetics | Desmoglein 2 - genetics | Penetrance | Potassium Channels, Inwardly Rectifying - genetics | Sequence Analysis, DNA | Ryanodine Receptor Calcium Release Channel - genetics | Pedigree | Ankyrins - genetics | High-Throughput Nucleotide Sequencing | Cohort Studies | Cardiac arrhythmia | Copy number | Genes | Insertion | Ryanodine receptors | Genetic screening | Gene sequencing | Complexity | Proteins | Defibrillators | Genetic analysis | Electrocardiography | Potassium channels (voltage-gated) | Heart diseases | Ion channels (cyclic nucleotide-gated) | Potassium channels (inwardly-rectifying) | Decision making | Data processing | Genetic diversity | Patients | Coronary artery disease | Substrates | Diseases | Genetic variance | KCNQ1 protein | Mutation | Variation | Index Medicus | Malalties | Heart | Aspectes genètics | Arítmia | Arrhythmia | Cor | Genetic aspects
Journal Article
Nature genetics, ISSN 1546-1718, 03/2009, Volume 41, Issue 4, pp. 399 - 406
Journal Article
PLoS genetics, ISSN 1553-7404, 09/2009, Volume 5, Issue 9, pp. e1000649 - e1000649
Journal Article
Epilepsia (Copenhagen), ISSN 0013-9580, 09/2010, Volume 51, Issue 9, pp. 1650 - 1658
Summary Mutations in a number of genes encoding voltage‐gated sodium channels cause a variety of epilepsy syndromes in humans, including genetic (generalized... 
Genetics | Knockout mice | GEFS | Dravet syndrome |