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FASEB Journal, ISSN 0892-6638, 03/2006, Volume 20, Issue 3, pp. 542 - 544
It is widely believed that the potencies of nonsteroid anti-inflammatory drugs ( NSAIDs) as inhibitors of cyclooxygenase ( COX) are influenced by protein... 
SITE | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | nonsteroid anti-inflammatory drugs | coxibs | PROSTAGLANDIN H-2 SYNTHASE | CELL BIOLOGY | CYCLO-OXYGENASE-2 | THERAPY | FLUID | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGY | prostaglandins | SELECTIVITY | Organic Chemicals - cerebrospinal fluid | Humans | Naproxen - pharmacology | Synovial Fluid - metabolism | Pyrazoles - cerebrospinal fluid | Sodium Salicylate - pharmacology | Lactones - pharmacology | Aspirin - cerebrospinal fluid | Cell Line - drug effects | Calcium - physiology | Pyrazoles - blood | Organic Chemicals - pharmacology | Dinoprostone - cerebrospinal fluid | Diclofenac - cerebrospinal fluid | Aspirin - pharmacology | Sulfones - cerebrospinal fluid | Aspirin - blood | Thiazines - blood | Sulfonamides - pharmacology | Indomethacin - cerebrospinal fluid | Indomethacin - pharmacology | Cyclooxygenase 1 - drug effects | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - blood | Diclofenac - pharmacology | Thiazoles - blood | Thromboxane A2 - blood | Cerebrospinal Fluid Proteins - pharmacology | Dinoprostone - biosynthesis | Lactones - cerebrospinal fluid | Blood Platelets - enzymology | Cyclooxygenase 2 Inhibitors - cerebrospinal fluid | Sodium Salicylate - cerebrospinal fluid | Sulfones - pharmacology | Blood Proteins - pharmacology | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Naproxen - cerebrospinal fluid | Sodium Salicylate - blood | Thiazines - pharmacology | Cyclooxygenase 2 Inhibitors - blood | Cyclooxygenase Inhibitors - cerebrospinal fluid | Blood Platelets - drug effects | Sulfones - blood | Organic Chemicals - blood | Ionophores - pharmacology | Pyrazoles - pharmacology | Sulfonamides - cerebrospinal fluid | Cyclooxygenase 2 Inhibitors - pharmacology | Thiazoles - cerebrospinal fluid | Celecoxib | Diclofenac - blood | Dinoprostone - blood | Naproxen - blood | Organ Specificity | Calcimycin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Indomethacin - blood | Protein Binding | Thiazines - cerebrospinal fluid | Thiazoles - pharmacology
Journal Article
Brazilian Journal of Medical and Biological Research, ISSN 0100-879X, 1986, Volume 19, Issue 2, pp. 279 - 286
Journal Article
Lung, ISSN 0341-2040, 1987, Volume 165, Issue 3, p. 173
The experiments described here were designed to investigate the possibility that central stimulation of respiration by salicylates may be due to changes in... 
Protons | Animals | Bicarbonates - cerebrospinal fluid | Respiration - drug effects | Dogs | Sodium Salicylate - pharmacology | Acid-Base Equilibrium - drug effects | Cerebrospinal Fluid - drug effects
Journal Article
Archives of Otolaryngology–Head & Neck Surgery, ISSN 0886-4470, 02/1988, Volume 114, Issue 2, pp. 186 - 191
• In four experiments, 54 pigmented rats were used to examine the time course of sodium salicylate uptake in serum, cerebrospinal fluid, and perilymph.... 
Salicylates - blood | Conditioning (Psychology) - drug effects | Rats | Salicylates - cerebrospinal fluid | Sodium Salicylate - pharmacokinetics | Rats, Inbred Strains | Pigmentation | Animals | Salicylic Acid | Perilymph - metabolism | Pentobarbital | Anesthesia | Behavior, Animal - drug effects | Water Deprivation - drug effects
Journal Article
by Liu, X.Y and Li, C.J
Science in China. Series B, Chemistry, life sciences & earth sciences, ISSN 1001-652X, 1989, Volume 32, Issue 10, pp. 1215 - 1223
To further evaluate the causality between endogenous pyrogen (EP)-induced fever and cyclic adenosine-3',5'-monophosphate (cyclic AMP) level, the effects of... 
CHEMISTRY | Cyclic AMP - blood | Rabbits | Cyclic AMP - cerebrospinal fluid | Sodium Salicylate - therapeutic use | Body Temperature - drug effects | Fever - metabolism | Male | Pyrogens | Fever - chemically induced | Sodium Salicylate - pharmacology | Animals | Female | Fever - drug therapy
Journal Article
SCI. SIN, ISSN 0582-236X, 01/1989, Volume 32, Issue 10, pp. 1215 - 1223
To further evaluate the causality between endogenous pyrogen-induced fever and cyclic adenosine-3',5'-monophosphate level, the effects of sodium salicylate on... 
sodium salicylate | cerebrospinal fluid | cyclic AMP
Journal Article
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2016, Volume 11, Issue 4, p. e0153386
This study investigated the effect of systemic salicylate on central auditory and non-auditory structures in mice. Since cochlear hair cells are known to be... 
OUTER HAIR-CELLS | RESONANCE-IMAGING MEMRI | INDUCED TINNITUS | BEHAVIORAL PARADIGM | GUINEA-PIG COCHLEA | ANTI-INFLAMMATORY DRUGS | MULTIDISCIPLINARY SCIENCES | RAT INFERIOR COLLICULUS | PRIMARY AUDITORY-CORTEX | NEURAL ACTIVITY | NOISE-INDUCED HYPERACTIVITY | Amygdala - chemistry | Kanamycin - toxicity | Auditory Cortex - metabolism | Male | Salicylates - chemistry | Cochlea - metabolism | Female | Salicylates - metabolism | Hypothalamus - chemistry | Hearing Loss - chemically induced | Auditory Cortex - drug effects | Amygdala - diagnostic imaging | Hypothalamus - diagnostic imaging | Amygdala - metabolism | Hearing Loss - pathology | Manganese - chemistry | Auditory Threshold | Radiography | Magnetic Resonance Imaging | Animals | Hypothalamus - metabolism | Manganese - metabolism | Cochlea - drug effects | Hearing Loss - diagnostic imaging | Mice | Complications and side effects | Care and treatment | Kanamycin | Research | Salicylates | Health aspects | Risk factors | Hearing loss | Neuroimaging | Brain | Neurosciences | Nuclear magnetic resonance--NMR | Amygdala | Calcium | Noise | Hyperactivity | Hair cells | Otolaryngology | Hypothalamus | Medical schools | Rodents | Tinnitus | Hair | Salicylic acid | Preoptic area | Data processing | Pharmacology | Hearing impairment | Trauma | Studies | Sodium salicylate | Brain research | Hypothalamus (anterior) | Magnetic resonance imaging | Sodium | Auditory system | Cochlea | Potassium | Manganese | Nuclear magnetic resonance | NMR
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, p. e0166973
Neuropeptide Y (NPY)/Agouti-related peptide (AgRP)-expressing neurons in the hypothalamus induce feeding and decrease energy expenditure. With consumption of a... 
DIABETES-MELLITUS | TUMOR-NECROSIS-FACTOR | TARGETED DISRUPTION | ACTIVATED PROTEIN-KINASE | SODIUM-SALICYLATE | FOOD-INTAKE | MULTIDISCIPLINARY SCIENCES | ENDOPLASMIC-RETICULUM STRESS | HYPOTHALAMIC NEURONS | INDUCED INSULIN-RESISTANCE | I-KAPPA-B | Embryo, Mammalian - drug effects | Inflammation - chemically induced | Neurons - pathology | Male | Neuropeptide Y - genetics | Embryo, Mammalian - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Neuropeptide Y - metabolism | Salicylates - pharmacology | Inflammation - metabolism | Palmitates - pharmacology | Female | Neurons - metabolism | Hypothalamus - drug effects | Phosphorylation - drug effects | Neurons - drug effects | Biomarkers - metabolism | Metformin - pharmacology | Cells, Cultured | Hypothalamus - pathology | Agouti-Related Protein - metabolism | Hypoglycemic Agents - pharmacology | Gene Expression Regulation - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Animals | Hypothalamus - metabolism | Embryo, Mammalian - cytology | Agouti-Related Protein - genetics | Mice | Mice, Inbred BALB C | Phosphorylation | Peptides | Gene regulation | Homeostasis | Neuropeptides | Hypothalamus | Kinases | Palmitic acid | High fat diet | Interleukin 6 | Proteins | Signal transduction | Rodents | Tumor necrosis factor-TNF | Physiology | Pretreatment | Drug dosages | Neuropeptide Y | Obesity | NF-κB protein | Salicylic acid | Adenosine | Cytokines | Neurons | Secretion | Diabetes mellitus | Extracellular signal-regulated kinase | Energy expenditure | JNK protein | Inflammation | Tumor necrosis factor-α | Metabolism | Gene expression | Fatty acids | Feeding | Medicine | Sodium salicylate | Sodium | Insulin resistance | Metformin | Diabetes | Endoplasmic reticulum | Endocrinology | Apoptosis
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, p. e0126956
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2012, Volume 7, Issue 10, p. e46969
Sodium salicylate (NaSal), an aspirin metabolite, can cause tinnitus in animals and human subjects. To explore neural mechanisms underlying salicylate-induced... 
PYRAMIDAL NEURONS | LIMBIC SYSTEM | BEHAVIORAL PARADIGM | SODIUM-SALICYLATE | AUDITORY-CORTEX | MULTIDISCIPLINARY SCIENCES | NEURAL ACTIVITY | POSTNATAL-DEVELOPMENT | GABA(B) RECEPTORS | REBOUND DEPOLARIZATION | INFERIOR COLLICULUS | Rats, Wistar | Male | Geniculate Bodies - drug effects | Inferior Colliculi - drug effects | Excitatory Postsynaptic Potentials - drug effects | Geniculate Bodies - physiopathology | Tinnitus - chemically induced | Neurons - physiology | Reflex, Startle - drug effects | Female | Synaptic Transmission - drug effects | Neurons - drug effects | Action Potentials - drug effects | Tinnitus - physiopathology | Membrane Potentials - drug effects | Inferior Colliculi - physiopathology | Acoustic Stimulation | Rats | Receptors, N-Methyl-D-Aspartate - physiology | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Patch-Clamp Techniques | Animals | Receptors, GABA-A - physiology | Neural Inhibition - drug effects | Inhibitory Postsynaptic Potentials - drug effects | Sodium Salicylate - toxicity | Neurons | Aspirin | Tinnitus | Colliculus | Neurosciences | Laboratories | Inferior colliculus | Brain slice preparation | Action potential | Depolarization | Borides | Synaptic transmission | Thalamus | Life sciences | Membrane potential | Cortex (auditory) | Medial geniculate body | Salicylic acid | Magnesium compounds | Variance analysis | Studies | Sodium salicylate | Brain research | Sodium
Journal Article