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1. Full Text Intrarenal dopamine deficiency leads to hypertension and decreased longevity in mice
by Zhang, Ming-Zhi and Yao, Bing and Wang, Suwan and Fan, Xiaofeng and Wu, Guanqing and Yang, Haichun and Yin, Huiyong and Yang, Shilin and Harris, Raymond C
The Journal of clinical investigation, ISSN 0021-9738, 07/2011, Volume 121, Issue 7, pp. 2845 - 2854
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Renin - metabolism | Receptors, Drug - genetics | Sodium-Bicarbonate Symporters - genetics | Sodium-Potassium-Chloride Symporters - metabolism | Sodium-Hydrogen Exchangers - metabolism | Dopamine - deficiency | Dopamine - urine | Aldosterone - metabolism | Kidney - metabolism | Cyclooxygenase 2 - genetics | Sodium-Hydrogen Exchangers - genetics | Aromatic-L-Amino-Acid Decarboxylases - metabolism | Kidney Tubules, Proximal - enzymology | Kidney - physiopathology | Sodium-Potassium-Chloride Symporters - genetics | Kidney - anatomy & histology | Hypertension - physiopathology | Receptors, Drug - metabolism | Sodium-Bicarbonate Symporters - metabolism | Symporters - metabolism | Mice, Knockout | Aquaporin 2 - metabolism | Solute Carrier Family 12, Member 1 | Animals | Solute Carrier Family 12, Member 3 | Symporters - genetics | Cyclooxygenase 2 - metabolism | Mice | Aquaporin 2 - genetics | Longevity - physiology | Aromatic-L-Amino-Acid Decarboxylases - genetics | Sodium-Hydrogen Exchanger 3 | Hypertension | Physiological aspects | Dopamine | Research | Risk factors | Decarboxylases | Index Medicus | Abridged Index Medicus
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2. Full Text The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice
by Leviel, Françoise and Hübner, Christian A and Houillier, Pascal and Morla, Luciana and El Moghrabi, Soumaya and Brideau, Gaëlle and Hatim, Hassan and Parker, Mark D and Kurth, Ingo and Kougioumtzes, Alexandra and Sinning, Anne and Pech, Vladimir and Riemondy, Kent A and Miller, R. Lance and Hummler, Edith and Shull, Gary E and Aronson, Peter S and Doucet, Alain and Wall, Susan M and Chambrey, Régine and Eladari, Dominique
The Journal of clinical investigation, ISSN 0021-9738, 05/2010, Volume 120, Issue 5, pp. 1627 - 1635
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Xenopus | Sodium - chemistry | Oocytes - metabolism | Mice, Inbred C57BL | Mice, Transgenic | Sodium Chloride Symporter Inhibitors - pharmacology | Sodium-Bicarbonate Symporters - metabolism | Mice, Knockout | Kidney Tubules, Collecting - metabolism | Chloride-Bicarbonate Antiporters - metabolism | Kidney - metabolism | Animals | Electrophysiology - methods | Hydrochlorothiazide - pharmacology | Models, Biological | Amiloride - pharmacology | Mice | Index Medicus | Abridged Index Medicus
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3. Full Text MCT1 and MCT4 Expression and Lactate Flux Activity Increase during White and Brown Adipogenesis and Impact Adipocyte Metabolism
by Petersen, Charlotte and Nielsen, Mette D and Andersen, Elise S and Basse, Astrid L and Isidor, Marie S and Markussen, Lasse K and Viuff, Birgitte M and Lambert, Ian H and Hansen, Jacob B and Pedersen, Stine F
Scientific reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 13101 - 13
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Humans | Lactic Acid - metabolism | Sodium-Bicarbonate Symporters - genetics | Adipose Tissue, White - metabolism | Adipocytes - cytology | Isoproterenol | Sodium-Bicarbonate Symporters - metabolism | Symporters - metabolism | Adipogenesis - physiology | Muscle Proteins - genetics | Adipose Tissue, Brown - cytology | Monocarboxylic Acid Transporters - metabolism | Adipose Tissue, White - cytology | Animals | Adipocytes - metabolism | Symporters - genetics | HEK293 Cells | Muscle Proteins - metabolism | Adipose Tissue, Brown - metabolism | Mice | Monocarboxylic Acid Transporters - genetics | Adipogenesis - genetics | Thermogenesis | Adipose tissue | Oxidative metabolism | Homeostasis | Glycolysis | mRNA | Norepinephrine | Lactic acid | Adipocytes | Metabolism | Protein turnover | Adipogenesis | Index Medicus
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4. Full Text Na+, HCO3 --cotransporter NBCn1 increases pHi gradients, filopodia, and migration of smooth muscle cells and promotes arterial remodelling
by Boedtkjer, Ebbe and Bentzon, Jacob F and Dam, Vibeke S and Aalkjaer, Christian
Cardiovascular research, ISSN 0008-6363, 08/2016, Volume 111, Issue 3, pp. 227 - 239
Restenosis | Remodelling | Smooth muscle | Carotid arteries | Blood flow | Muscle, Smooth, Vascular - metabolism | Sodium-Bicarbonate Symporters - antagonists & inhibitors | Sodium-Bicarbonate Symporters - genetics | Myocytes, Smooth Muscle - pathology | Mice, 129 Strain | Sodium - metabolism | Pseudopodia - pathology | RNA, Messenger - metabolism | Pseudopodia - drug effects | Carotid Artery Injuries - genetics | Vascular Remodeling - drug effects | Myocytes, Smooth Muscle - drug effects | Myocytes, Smooth Muscle - metabolism | Carotid Artery Injuries - metabolism | Carotid Artery Injuries - pathology | Disease Models, Animal | Muscle, Smooth, Vascular - drug effects | Carbon Dioxide - metabolism | Signal Transduction | Carotid Artery, Common - metabolism | Tissue Culture Techniques | RNA, Messenger - genetics | Cells, Cultured | Sodium-Bicarbonate Symporters - deficiency | Genotype | Sodium-Bicarbonate Symporters - metabolism | Mice, Knockout | Cell Movement - drug effects | Muscle, Smooth, Vascular - pathology | Phenotype | Animals | Pseudopodia - metabolism | Bicarbonates - metabolism | Carotid Artery, Common - pathology | Cell Proliferation - drug effects | Hydrogen-Ion Concentration | Hypertrophy | Index Medicus
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5. Full Text Mechanisms of CO2/H+ sensitivity of astrocytes
by Turovsky, Egor and Theparambil, Shefeeq M and Kasymov, Vitaliy and Deitmer, Joachim W and Del Arroyo, Ana Gutierrez and Ackland, Gareth L and Corneveaux, Jason J and Allen, April N and Huentelman, Matthew J and Kasparov, Sergey and Marina, Nephtali and Gourine, Alexander V
The Journal of neuroscience, ISSN 0270-6474, 10/2016, Volume 36, Issue 42, pp. 10750 - 10758
Chemosensitivity | Hypercapnia | Breathing | Acidosis | Respiration | Brainstem | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Astrocytes - drug effects | Hydrogen - pharmacology | Sodium-Bicarbonate Symporters - antagonists & inhibitors | Sodium-Bicarbonate Symporters - genetics | Rats | Signal Transduction - genetics | Sodium - metabolism | Exocytosis | Sodium-Bicarbonate Symporters - metabolism | Neuroglia - drug effects | Animals | Signal Transduction - drug effects | Sodium-Calcium Exchanger - metabolism | Adenosine Triphosphate - metabolism | Bicarbonates - metabolism | Neuroglia - metabolism | Sodium-Calcium Exchanger - antagonists & inhibitors | Carbon Dioxide - pharmacology | In Vitro Techniques | Calcium Signaling | Astrocytes - metabolism | Hydrogen-Ion Concentration | Index Medicus | brainstem | respiration | chemosensitivity | breathing | acidosis | hypercapnia
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6. Full Text The SLC4 family of bicarbonate (HCO3-) transporters
by Romero, Michael F and Chen, An-Ping and Parker, Mark D and Boron, Walter F
Molecular aspects of medicine, ISSN 0098-2997, 04/2013, Volume 34, Issue 2-3, pp. 159 - 182
Bicarbonate | Boron | Chloride | Sodium | Exchanger | Carbonate | Cotransporter | SLC4 | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Chloride-Bicarbonate Antiporters - physiology | Multigene Family - genetics | Chloride-Bicarbonate Antiporters - genetics | Humans | Sodium-Bicarbonate Symporters - genetics | Models, Molecular | Sodium-Bicarbonate Symporters - metabolism | Chloride-Bicarbonate Antiporters - metabolism | Erythrocytes - metabolism | Bicarbonates - metabolism | Protein Conformation | Gene Components | Sodium-Bicarbonate Symporters - physiology | Hypertension | Physiological aspects | Universities and colleges | Carbonates | Biomedical engineering | Membrane proteins | Index Medicus | sodium | exchanger | chloride | carbonate | boron | cotransporter
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7. Full Text The Na+/H+ exchanger NHE1, but not the Na+, HCO3- cotransporter NBCn1, regulates motility of MCF7 breast cancer cells expressing constitutively active ErbB2
by Lauritzen, Gitte and Stock, Christian-Martin and Lemaire, Justine and Lund, Stine F and Jensen, Mie Frid and Damsgaard, Britt and Petersen, Katrine Seide and Wiwel, Maria and Rønnov-Jessen, Lone and Schwab, Albrecht and Pedersen, Stine Falsig
Cancer letters, ISSN 0304-3835, 04/2012, Volume 317, Issue 2, pp. 172 - 183
Signaling | Cytoskeleton | Motility | pH-regulation | HER2 | Adhesion | PH-regulation | Life Sciences & Biomedicine | Oncology | Science & Technology | Phosphorylation | Receptor, ErbB-2 - genetics | Sodium-Bicarbonate Symporters - antagonists & inhibitors | Humans | Sodium-Bicarbonate Symporters - genetics | Receptor, ErbB-2 - metabolism | Amiloride - analogs & derivatives | Immunoblotting | Phosphatidylinositol 3-Kinases - metabolism | Cell Movement - genetics | Cell Movement - physiology | Breast Neoplasms - metabolism | Sodium-Hydrogen Exchangers - metabolism | Cation Transport Proteins - metabolism | Cation Transport Proteins - genetics | Cytoskeletal Proteins - metabolism | Female | Sodium-Hydrogen Exchangers - genetics | Benzamides - pharmacology | Membrane Proteins - metabolism | Microfilament Proteins - metabolism | Chromones - pharmacology | Culture Media, Serum-Free - pharmacology | Proto-Oncogene Proteins c-akt - metabolism | Cell Adhesion - genetics | Enzyme Inhibitors - pharmacology | Morpholines - pharmacology | Cell Adhesion - drug effects | Reverse Transcriptase Polymerase Chain Reaction | Sulfonamides - pharmacology | Sodium-Bicarbonate Symporters - metabolism | Integrin beta1 - metabolism | Cell Movement - drug effects | Breast Neoplasms - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Cell Adhesion - physiology | Amiloride - pharmacology | Cell Line, Tumor | Sodium-Hydrogen Exchanger 1 | Proto-Oncogene Proteins c-akt - antagonists & inhibitors | Hydrogen-Ion Concentration | Index Medicus
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8. Physiology, pharmacology and pathophysiology of the ph regulatory transport proteins NHE1 and NBCN1: Similarities, differences, and implications for cancer therapy
by Boedtkjer, E and Bunch, L and Pedersen, S.F
Current pharmaceutical design, ISSN 1381-6128, 2012, Volume 18, Issue 10, pp. 1345 - 1371
SLC4A7 | Bicarbonate | DIDS | EIPA | Cariporide | S0859 | Acidification | Cancer | SLC9A1 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Neoplasms - metabolism | Cation Transport Proteins - antagonists & inhibitors | Sodium-Bicarbonate Symporters - antagonists & inhibitors | Humans | Sodium-Bicarbonate Symporters - genetics | Sodium-Bicarbonate Symporters - metabolism | Sodium-Hydrogen Exchangers - metabolism | Cation Transport Proteins - metabolism | Cation Transport Proteins - genetics | Sodium-Hydrogen Exchangers - genetics | Antineoplastic Agents - pharmacology | Gene Expression Regulation, Neoplastic - physiology | Sodium-Hydrogen Exchanger 1 | Sodium-Hydrogen Exchangers - antagonists & inhibitors
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