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1. Full Text Na + /H + exchanger 1, Na + /Ca2 + exchanger 1 and calmodulin complex regulates interleukin 6-mediated cellular behavior of human hepatocellular carcinoma
by Xu, Jingyu and Ji, Bei and Wen, Guorong and Yang, Yuan and Jin, Hai and Liu, Xuemei and Xie, Rui and Song, Wenfeng and Song, Penghong and Dong, Hui and Tuo, Biguang
Carcinogenesis (New York), ISSN 0143-3334, 10/2015, Volume 37, Issue 3, pp. 290 - 300
Life Sciences & Biomedicine | Oncology | Science & Technology | Immunohistochemistry | Calmodulin - metabolism | Immunoprecipitation | Humans | Male | Blotting, Western | Gene Knockdown Techniques | Sodium-Hydrogen Exchangers - metabolism | Animals | Heterografts | Cation Transport Proteins - metabolism | Mice, Nude | Sodium-Calcium Exchanger - metabolism | Carcinoma, Hepatocellular - pathology | Cell Line, Tumor | Liver Neoplasms - pathology | Mice | Mice, Inbred BALB C | RNA, Small Interfering | Gene Expression Regulation, Neoplastic - physiology | Interleukin-6 - metabolism | Real-Time Polymerase Chain Reaction | Sodium-Hydrogen Exchanger 1 | Carcinoma, Hepatocellular - metabolism | Index Medicus
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2. Full Text The SLC8 gene family of sodium–calcium exchangers (NCX) – Structure, function, and regulation in health and disease
by Khananshvili, Daniel
Molecular aspects of medicine, ISSN 0098-2997, 04/2013, Volume 34, Issue 2-3, pp. 220 - 235
SLC8 | NCX | Regulation | Expression | Splice variants | Isoforms | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Multigene Family - genetics | Vasoconstriction - genetics | Allosteric Regulation - genetics | Mitochondrial Membrane Transport Proteins - metabolism | Cardiovascular Diseases - metabolism | Calcium - metabolism | Humans | Models, Molecular | Sodium-Calcium Exchanger - genetics | Neurodegenerative Diseases - metabolism | Sodium-Calcium Exchanger - physiology | Myocardial Contraction - genetics | Animals | Protein Isoforms - metabolism | Sodium-Calcium Exchanger - metabolism | Homeostasis - physiology | Protein Conformation | Mice | Protein Isoforms - genetics | Animal genetics | Proteins | Hypertension | Genes | Genetic research | Physiological aspects | Diabetes | Index Medicus
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3. Full Text The Pump, the Exchanger, and Endogenous Ouabain: Signaling Mechanisms That Link Salt Retention to Hypertension
by Blaustein, Mordecai P and Zhang, Jin and Chen, Ling and Song, Hong and Raina, Hema and Kinsey, Stephen P and Izuka, Michelle and Iwamoto, Takahiro and Kotlikoff, Michael I and Lingrel, Jerry B and Philipson, Kenneth D and Wier, W Gil and Hamlyn, John M
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 02/2009, Volume 53, Issue 2, Part 2 Suppl, pp. 291 - 298
Cardiology. Vascular system | Biological and medical sciences | Arterial hypertension. Arterial hypotension | Medical sciences | Clinical manifestations. Epidemiology. Investigative techniques. Etiology | Blood and lymphatic vessels | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Sodium-Calcium Exchanger - metabolism | Humans | Signal Transduction - physiology | Sodium Chloride - metabolism | Disease Models, Animal | Hypertension - metabolism | Ouabain - metabolism | Index Medicus | Sodium Pump | Myogenic Tone | Calcium | Sodium | Salt-dependent hypertension | Calcium Exchanger
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4. Full Text Na+ transport in the normal and failing heart — Remember the balance
by Despa, Sanda and Bers, Donald M
Journal of molecular and cellular cardiology, ISSN 0022-2828, 2013, Volume 61, pp. 2 - 10
Cardiovascular | Heart failure | Intracellular Na+ concentration | Na+/H+ exchanger | Na+/Ca2 + exchanger | Na+/K+-ATPase | Myocyte | Na | ATPase | exchanger | H | concentration | Intracellular Na | K | Ca | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cell Biology | Action Potentials | Myocardial Contraction | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Biological Transport | Sodium-Calcium Exchanger - metabolism | Humans | Heart Failure - physiopathology | Myocytes, Cardiac - metabolism | Heart Failure - metabolism | Sodium - metabolism | Voltage-Gated Sodium Channels - metabolism | Index Medicus | heart failure | H+ exchanger | Ca2+ exchanger | myocyte | Na+ | K+-ATPase | intracellular Na+ concentration
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5. Full Text Mechanism of extracellular ion exchange and binding-site occlusion in a sodium/calcium exchanger
by Liao, Jun and Marinelli, Fabrizio and Lee, Changkeun and Huang, Yihe and Faraldo-Gómez, José D and Jiang, Youxing and UChicago, LLC., Argonne, IL (United States)
Nature structural & molecular biology, ISSN 1545-9993, 06/2016, Volume 23, Issue 6, pp. 590 - 599
Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Archaeal Proteins - metabolism | Calcium - metabolism | Sodium-Calcium Exchanger - chemistry | Archaeal Proteins - chemistry | Crystallography, X-Ray | Sodium - metabolism | Strontium - metabolism | Molecular Dynamics Simulation | Sodium-Calcium Exchanger - metabolism | Ion Exchange | Protein Conformation | Methanocaldococcus - metabolism | Molecular Docking Simulation | Binding Sites | Methanocaldococcus - chemistry | Euryarchaeota | Cell interaction | Genetic aspects | Ion exchange | Observations | Health aspects | Sodium channels | Calcium channels | Homeostasis | Ion transport | Properties | Proteins | Membranes | Binding sites | Crystal structure | Index Medicus | X-ray crystallography | INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY | membrane proteins | BASIC BIOLOGICAL SCIENCES | computational biology and bioinformatics
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6. Full Text ORM‐10103, a novel specific inhibitor of the Na+/Ca2+ exchanger, decreases early and delayed afterdepolarizations in the canine heart
by Jost, N and Nagy, N and Corici, C and Kohajda, Z and Horváth, A and Acsai, K and Biliczki, P and Levijoki, J and Pollesello, P and Koskelainen, T and Otsomaa, L and Tóth, A and Papp, J Gy and Varró, A and Virág, L
British journal of pharmacology, ISSN 0007-1188, 10/2013, Volume 170, Issue 4, pp. 768 - 778
EAD | NCX | sodium/calcium exchanger | DAD | ORM‐10103 | ORM-10103 | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Potassium - metabolism | Anti-Arrhythmia Agents - pharmacology | Male | Sodium - metabolism | Action Potentials | Dose-Response Relationship, Drug | Purkinje Fibers - drug effects | Time Factors | Sodium-Calcium Exchanger - metabolism | Female | Papillary Muscles - metabolism | Sodium-Calcium Exchanger - antagonists & inhibitors | Benzopyrans - pharmacology | Guinea Pigs | Purkinje Fibers - metabolism | Animals | Myocytes, Cardiac - drug effects | Calcium Signaling - drug effects | Calcium Channels, L-Type - drug effects | Dogs | Myocytes, Cardiac - metabolism | Heart Ventricles - metabolism | Pyridines - pharmacology | Calcium Channels, L-Type - metabolism | Papillary Muscles - drug effects | Heart Ventricles - drug effects | Index Medicus | Research Paper With | sodium | calcium exchanger
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7. Full Text Increased sodium/calcium exchanger activity enhances beta-adrenergic–mediated increase in heart rate: Whole-heart study in a homozygous sodium/calcium exchanger overexpressor mouse model
by Kaese, Sven, MD and Bögeholz, Nils, MD and Pauls, Paul, MSc and Dechering, Dirk, MD and Olligs, Jan, MD and Kölker, Katharina, VetD and Badawi, Sascha, BS and Frommeyer, Gerrit, MD and Pott, Christian, MD and Eckardt, Lars, MD
Heart rhythm, ISSN 1547-5271, 2017, Volume 14, Issue 8, pp. 1247 - 1253
Cardiovascular | Heart failure | Heart rate | Langendorff-perfused heart | Sodium/calcium exchanger | Sinus node | Mouse | Beta-adrenergic stimulation | Atrioventricular node | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Calcium - metabolism | Myocardial Contraction - physiology | Sinoatrial Node - physiopathology | Adrenergic beta-Agonists - pharmacology | Mice, Transgenic | Heart Failure - metabolism | Heart Failure - drug therapy | Sodium-Calcium Exchanger - drug effects | Myocytes, Cardiac - pathology | Animals | Isoproterenol - pharmacology | Sodium-Calcium Exchanger - biosynthesis | Heart Rate - physiology | Myocytes, Cardiac - metabolism | Sinoatrial Node - metabolism | Mice | Disease Models, Animal | Heart | Heart beat | Analysis | Atrial fibrillation | Genetic engineering | Cardiovascular agents | Index Medicus
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8. Full Text NCLX: The mitochondrial sodium calcium exchanger
by Boyman, Liron and Williams, George S.B and Khananshvili, Daniel and Sekler, Israel and Lederer, W.J
Journal of molecular and cellular cardiology, ISSN 0022-2828, 2013, Volume 59, pp. 205 - 213
Cardiovascular | Sodium/calcium exchange | Mitochondria | Calcium transport | Computational model | NCLX | Cardiac myocytes | Cardiac & Cardiovascular Systems | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cell Biology | Mitochondria - metabolism | Animals | Calcium - metabolism | Sodium-Calcium Exchanger - metabolism | Humans | Computational Biology | Index Medicus | calcium exchange | Sodium
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